GEISHA - A Chicken Embryo Gene Expression Database
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SUFU
SUFU negative regulator of hedgehog signaling

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolSUFU
Official Full NameSUFU negative regulator of hedgehog signaling
CGNC ID6132
also known assuppressor of fused homolog, SUFU, suppressor of fused homolog
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204264
PolypeptideNP_989595
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.2771
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly41565FBgn0005355
Human51684ENSG00000107882MIM:155255MIM:607035
Mouse24069ENSMUSG00000025231All phenotypic alleles (8):Targeted, knock-out(2) Targeted, other(5) Gene trapped(1) MGI:1345643
Xenopus100170148, 444442479288
Zebrafish100001615ZDB-GENE-030131-6223ZFIN:ZDB-GENE-030131-6223
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene374118
Ensembl GeneENSGALG00000008096
KEGGgga:374118

Entry 1

GEISHA IdSUFU.Aglyamova.2007Data SourcePublication
Complete cDNA Template Probeshow
ATGGAAGGCACGCGGCCTGGCGGGGCTGCCCCCGCGGGCGGGGCGGGCTCCGGCTCGGGCTCGGGCTCCAGCTCCTTCC
CGTCCCTCTTCCCGCCGGGCCTTCACGGAATCTACGGCGAGTGCCGCCGCCTCTACCCCGAGCAGCCCAACCCGCTGCA
GGTCACCGCCATCCTCAAGTACTGGTTGGGGGGACCCGATCCTCTGGACTACGTTAGCATGTACAGAAACATAGGGAAC
CCAGCGCTGAATGTTCCTGAGCACTGGCACTATGTCAGTTTTGGGTTAAGTGACTTGTATGGAGACAACAGAGTACATG
AGTTTACGGGAACAGATGGACCAAGTGGTTTTGGATTTGAGTTGACATTTCGACTAAAGAGAGAAACGGGGGAGTCAGC
TCCACCTACCTGGCCAGCAGAGTTAATGCAAGGCTTAGCAAGATATGTCTTCCAGTCAGAAAACACCTTCTGCAGCGGT
GACCATGTGTCATGGCACAGCCCTTTGGACAACAGTGAGTCCAGAATCCAGCATATGTTGCTGACAGAAGACCCTCAGA
TGCAGCCTGTGCAGACTCCTTTTGGGGTTGTTACTTTCCTACAGATTGTTGGGGTTTGCACTGAGGAACTGCATGCAGC
TCAGCAATGGAACGGGCAAGGAATCTTGGAGCTGCTTCGGACTGTCCCAGTAGCTGGAGGCCCTTGGCTGATAACAGAC
ATGCGAAGAGGAGAAACAATATTTGAAATTGACCCGCATCTGCAAGAGAGAGTCGACAAAGGGATTGAGACAGATGGCT
CAAACCTAAGTGGAGTGAGTGCCAAATGTGCCTGGGATGATCTCAGCCGGCCCCCTGAGGATGACGAAGACAGCAGGAG
CATTTGCATCGGAACCCAGCCGCGGCGGCTCTCCGGGAAAGATACGGAGCAAATCAGGGAGACTTTGCGAAGAGGGCTG
GAGATTAACAGCAAACCTGTTCTACCTCCAATAAATGCACAAAGACAGAATGGGTTGAACCATGACCGAGCACCAAGCC
GGAAGGACAGTTTAGAAAGCGAGAGCTCAGCAGCTATCATTCCTCATGAGCTAATCCGCACGAGACAGCTGGAAAGCGT
ACACCTGAAGTTTAACCAGGAGTCTGGAGCGCTGATTCCCCTCTGCCTAAGGGGAAGGCTCTTACATGGACGGCACTTT
ACATATAAAAGTATTACAGGGGACACAGCAATCACGTTTGTATCAACGGGAGTAGAAGGAGCATTTGCTACAGAGGAGC
ACCCCTATGCAGCACATGGACCTTGGTTACAAATCCTATTGACTGAAGAGTTCGTAGAGAGAATGCTGGAAGATTTAGA
AGATCTGAATTCTCCAGAGGAATTTAAACTTCCAAAGGAGTACAGCTGGCCTGAAAAGAAACTGAAAGTCTCCATCTTG
CCAGATGCTGTGTTCGACAACCCGCTGCATTAG
CitationAglyamova GV, Agarwala S. Gene expression analysis of the hedgehog signaling cascade in the chick midbrain and spinal cord. Dev Dyn. 2007 May;236(5):1363-73
CopyrightCopyright © 2007 Wiley-Liss, Inc.
CommentsAccording to the authors, "Digoxigenin- or FL-conjugated antisense riboprobes were prepared from chick cDNAs." As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (NM_204264).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 5
Hensen's Node
Neural Plate/Tube
Primitive Streak
 
7-12
stage 8
stage 10
Isthmus/MHB
Midbrain
Neural Plate/Tube
 
13-18
stage 15
Midbrain
Neural Plate/Tube
rostral Floor Plate
25-26
stage 26
Midbrain
Neural Plate/Tube
Tectum

Entry 2

GEISHA IdSUFU.Agarwala.2005Data SourcePublication
Complete cDNA Template Probeshow
ATGGAAGGCACGCGGCCTGGCGGGGCTGCCCCCGCGGGCGGGGCGGGCTCCGGCTCGGGCTCGGGCTCCAGCTCCTTCC
CGTCCCTCTTCCCGCCGGGCCTTCACGGAATCTACGGCGAGTGCCGCCGCCTCTACCCCGAGCAGCCCAACCCGCTGCA
GGTCACCGCCATCCTCAAGTACTGGTTGGGGGGACCCGATCCTCTGGACTACGTTAGCATGTACAGAAACATAGGGAAC
CCAGCGCTGAATGTTCCTGAGCACTGGCACTATGTCAGTTTTGGGTTAAGTGACTTGTATGGAGACAACAGAGTACATG
AGTTTACGGGAACAGATGGACCAAGTGGTTTTGGATTTGAGTTGACATTTCGACTAAAGAGAGAAACGGGGGAGTCAGC
TCCACCTACCTGGCCAGCAGAGTTAATGCAAGGCTTAGCAAGATATGTCTTCCAGTCAGAAAACACCTTCTGCAGCGGT
GACCATGTGTCATGGCACAGCCCTTTGGACAACAGTGAGTCCAGAATCCAGCATATGTTGCTGACAGAAGACCCTCAGA
TGCAGCCTGTGCAGACTCCTTTTGGGGTTGTTACTTTCCTACAGATTGTTGGGGTTTGCACTGAGGAACTGCATGCAGC
TCAGCAATGGAACGGGCAAGGAATCTTGGAGCTGCTTCGGACTGTCCCAGTAGCTGGAGGCCCTTGGCTGATAACAGAC
ATGCGAAGAGGAGAAACAATATTTGAAATTGACCCGCATCTGCAAGAGAGAGTCGACAAAGGGATTGAGACAGATGGCT
CAAACCTAAGTGGAGTGAGTGCCAAATGTGCCTGGGATGATCTCAGCCGGCCCCCTGAGGATGACGAAGACAGCAGGAG
CATTTGCATCGGAACCCAGCCGCGGCGGCTCTCCGGGAAAGATACGGAGCAAATCAGGGAGACTTTGCGAAGAGGGCTG
GAGATTAACAGCAAACCTGTTCTACCTCCAATAAATGCACAAAGACAGAATGGGTTGAACCATGACCGAGCACCAAGCC
GGAAGGACAGTTTAGAAAGCGAGAGCTCAGCAGCTATCATTCCTCATGAGCTAATCCGCACGAGACAGCTGGAAAGCGT
ACACCTGAAGTTTAACCAGGAGTCTGGAGCGCTGATTCCCCTCTGCCTAAGGGGAAGGCTCTTACATGGACGGCACTTT
ACATATAAAAGTATTACAGGGGACACAGCAATCACGTTTGTATCAACGGGAGTAGAAGGAGCATTTGCTACAGAGGAGC
ACCCCTATGCAGCACATGGACCTTGGTTACAAATCCTATTGACTGAAGAGTTCGTAGAGAGAATGCTGGAAGATTTAGA
AGATCTGAATTCTCCAGAGGAATTTAAACTTCCAAAGGAGTACAGCTGGCCTGAAAAGAAACTGAAAGTCTCCATCTTG
CCAGATGCTGTGTTCGACAACCCGCTGCATTAG
CitationAgarwala S, Aglyamova GV, Marma AK, Fallon JF, Ragsdale CW. Differential susceptibility of midbrain and spinal cord patterning to floor plate defects in the talpid2 mutant. Dev Biol. 2005 Dec 1;288(1):206-20. Epub 2005 Oct 21.
CopyrightCopyright © 2005 Elsevier Inc. All rights reserved.
CommentsAccording to the authors, "Digoxigenin (DIG)- and fluorescein-labeled riboprobes were synthesized from chick cDNA plasmids..." As information provided was insufficient to verify exact sequence used to synthesize probe,the sequence below was obtained from NCBI (NM_204264).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-26
stage 26
Midbrain
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.2771

Mouse

EmageMGI:1345643
EurexpressMGI:1345643
MGI GXDMGI:1345643

Frog

Xenbase479288

Fruit Fly

BDGPFBgn0005355

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030131-6223
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