GEISHA - A Chicken Embryo Gene Expression Database
Browse By
- Anatomical Location
- Stage
- Gene Name
- GEISHA ID
- Multiple Parameters
Search
- Quick Search
Data Class
Enter Text:
go
- Gene Family QuickSearch
Transcription Factors
Growth Factors
Receptors
MicroRNAs
- Human Disease Gene Search
Documents
- Downloads
- Protocols
- About GEISHA
- Contact Us
Resources
- Transgenic Birds
- Model Organism Databases
- Gene Expression Databases
- Genomic Resources
- Anatomical Atlases
- Chicken Stage Series
_

PDX1
pancreatic and duodenal homeobox 1

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolPDX1
Official Full Namepancreatic and duodenal homeobox 1
CGNC ID15657
also known aspancreas/duodenum homeobox protein 1, Insulin promoter factor 1 (IPF-1), Islet/duodenum homeobox-1 (IDX-1), Insulin upstream factor 1 (IUF-1), (Glucose-sensitive factor) (GSF). , Pancreas/duodenum homeobox protein 1 (PDX-1), Somatostatin- transactivating factor 1 (STF-1)
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
Gallus-Browse
Sequence Information
Genomic
RNAXM_001234635
PolypeptideXP_001234636
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST Profile
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human3651ENSG00000139515MIM:125853MIM:600733
Mouse18609All phenotypic alleles (11):Targeted, knock-out(3) Targeted, other(8) MGI:102851
Xenopus100490648, 100337610483330
Zebrafish30721ENSDARG00000002779ZDB-GENE-990415-122ZFIN:ZDB-GENE-990415-122
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene771348
Ensembl Gene
KEGGgga:771348

Entry 1

GEISHA IdPDX1.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerTACGAGGTGCCCCCCATCAG
Reverse cDNA Template PrimerAATTAACCCTCACTAAAGCGTCCCCCGCTTTTTGTCcDNA Template Length435
Forward cDNA Template Probeshow
GGGTTGCATTGATCGCATCTTCATTCTCGNCGGTTCGGAACAGATCTTGATGTGTCTCTCGGTCAGGCCTTCAAGAGGG
CACAGCTCCCCCGCCTCGGTCGGGAGATGTCCTTGAGTGAAGAGAAACTCCTTCTCCAGCTCCAGCAGCTGAGCCCTCG
TGTAGGCCGTCCGCGTCCTCTTGTTCTCCTCCGGCTCCACCACGTAGGAACCCCCTGCCCACTGCCCCTTCCAGGCGTG
CGACTTGGTGGACTTCATCCAGGCGAAAGGCACCTGCACCCGAGGCTCCTCCATCGCCCCCGGGTCCGCCCCGTCGGGG
AAAGGCACAACGTCCTGTTGGGGGGGAGGGAGGTGAGGGTGGTGATGTTGGTGGTGATGTACGTGGGAGAAACCGGCGT
CTTCGCTGATGGGGGGGGCTCAATAAAATCGCTCTGATTATCCTGTTACATTAAACCCGATTGCATCTTACTGTGTGCC
TGCTCCATGCCAGATATCTCTTGTGGGTCAAATGACTGCGTAGTCCGATCTACGGTAACCAACCTCCACATTGCTTCAG
GCATGATGGATACTTTCTATATAGGACCCACGTGCGATCTCCCGAGATGCCTGCCATGCCACTTATGCACATTAAGACC
TAGTCCCGTCCGGTTTCCGTGACTGCATTGAACACATGTTCTCCTGGTTCTCCCGTCGCGGCCATACACGATATCATCG
GTTCACTACTCATGATCTTCTTCTATGATCTCCCCAAGATCCGTCCTTAATCAAAAGATCCGGCCGGTCCTTCCCTGAC
GTCTTTAATTAAGACGTAATCTGTGCTAACCCATTGGACTGACCTGCCCCGATAATACACCGACTATCCTCTTCCGCTG
AATCCGTTCGAAAATATTCTTCTGCCATCCCTCCTGGATCAATACCGGTTTTCCCCCCAATTAGACTTCCATCTGTGGA
CAAAAATTATTGGTGGCCGGTTTTCGACATTTCCAACATTTCTCATTCCTTTCAAAATCTTTGCTTCCGCCAAATGGTT
GTGACTCGTTCCCTGTCCTTTTTGTCCTAAATAACATTTTTCCCCCCAGTTTATACCCCGGACCAAAGGGATTTTTTTC
TCCTGTAAACTTATTCTTTCACCCCCTTGAATTCCTGCTAAACGACTTTTGGCCCTTTTTAAGTCCAACTCTTTAAAGT
TTTTTCTTTCAGTCCGGGAGGAGGTTCCCCCCGGCCGGGGGTAATTCCCCCTCTAGATCCTTCGAATACCCCCTTTTGG
GATTTACAGTTCACCAAAGATGGTTAAACTTTACGCGAGGGTTTGTTTTCAAATCTTGTTAAGTTGCCCAATTGAAATA
CTTCCTTTCTTTTTAAGTTTCCTTTTGAAATTCTTATTCCTTTTATAATATTCAGTTCTCCCAGCCGATTTTTTTTAAT
TTTTGACATTTCTCTCCTTCTTTTTGANGTGATGCCCCACCCCACCCGCCTTAGAGCATAGACCATATTACTTCTCGAT
CTCCTATACA
CommentsNo specific expression detected at or before stage 5.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 6
Neural Plate/Tube
Primitive Streak
Low level expression.
7-12
stage 7
stage 9
stage 9
stage 11
stage 11
stage 11
stage 11
stage 12
stage 12
stage 12
Amnion
Anterior Intestinal Portal
Anterior Neuropore
Blood Islands
Dermomyotome
Ectoderm
Endoderm
Extraembryonic Mesoderm
Forebrain
Foregut
Head Mesenchyme
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Notochord
Primitive Streak
Somites
extraembryonic endoderm
 
13-18
stage 16
stage 18
Endoderm
Neural Plate/Tube
Pancreas
 
19-24
stage 22
stage 23
Gut
Pancreas
 
25
stage 25
Gut
Pancreas
 

Entry 2

GEISHA IdPDX1.Pedersen.2005Data SourcePublication
Complete cDNA Template Probeshow
ATGAACACCGAGGAGCAGTACTACGCCTCCGCGCAGCTCTACAAGGAGCCGTGCGCCTTTCAGAGAGCGCAGGATTACA
GCCCCAGCCCCCCCGCCTGCCTCTACGTGGGCCGGCAGCAGCAGGCTCCGTACCCCGGCTCTCTGGGGGCGCTGGAGCA
GGGCAGCCCGTCGGACATCTCGCCCTACGAGGTGCCCCCCATCAGCGAGGATGCCGGGGTCTCCCACCTGCATCACCAC
CACCATCACCACCCTCACCTCCCTCCCCCCCACCAGGACGCTCTGCCTTTCGCCGACGGGGCGGACCCGGGGGCGATGG
AGGAGCCTCGGGTGCAGGTGCCTTTCGCCTGGATGAAGTCCACCAAGTCGCACGCCTGGAAGGGGCAGTGGGCAGGGGG
TTCCTACGTGGTGGAGCCGGAGGAGAACAAGAGGACGCGGACGGCCTACACGAGGGCTCAGCTGCTGGAGCTGGAGAAG
GAGTTTCTCTTCAACAAGTACATCTCCCGACCGAGGCGGGTGGAGCTGGCCGTCATGTTAAACCTGACCGAGAGACACA
TCAAGATCTGGTTCCAGAACCGACGGATGAAATGGAAGAAAGAAGAAGACAAAAAGCGGGGGACGGCCAACAGCGCTGA
TCCCGAGCAGGACTGCGTCGTGTCCTCCGGGAAGCTGCAGGGCAAAGAGGATCTGCAGCCGTGA
CitationPedersen JK, Nelson SB, Jorgensen MC, Henseleit KD, Fujitani Y, Wright CV, Sander M, Serup P; Beta Cell Biology Consortium. Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol. 2005 Dec 15;288(2):487-501.
CopyrightCopyright © 2005 Elsevier Inc. All rights reserved.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_001234635).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 10
stage 11
Endoderm
Pancreas
Chicken embryos with antisense probes recognizing Nkx6.1, Nkx6.2, Nkx6.3, Nkx2.2, and Pdx1.
Prospective Pancreatic Endoderm
13-17
stage 15
stage 15
stage 17
Endoderm
Pancreas
Chicken embryos with antisense probes recognizing Nkx6.1, Nkx6.2, Nkx6.3, Nkx2.2, and Pdx1.
Pancreatic Buds
Pancreatic Primordia

Entry 3

GEISHA IdPDX1.Kumar.2003Data SourcePublication
Complete cDNA Template Probeshow
ATGAACACCGAGGAGCAGTACTACGCCTCCGCGCAGCTCTACAAGGAGCCGTGCGCCTTTCAGAGAGCGCAGGATTACA
GCCCCAGCCCCCCCGCCTGCCTCTACGTGGGCCGGCAGCAGCAGGCTCCGTACCCCGGCTCTCTGGGGGCGCTGGAGCA
GGGCAGCCCGTCGGACATCTCGCCCTACGAGGTGCCCCCCATCAGCGAGGATGCCGGGGTCTCCCACCTGCATCACCAC
CACCATCACCACCCTCACCTCCCTCCCCCCCACCAGGACGCTCTGCCTTTCGCCGACGGGGCGGACCCGGGGGCGATGG
AGGAGCCTCGGGTGCAGGTGCCTTTCGCCTGGATGAAGTCCACCAAGTCGCACGCCTGGAAGGGGCAGTGGGCAGGGGG
TTCCTACGTGGTGGAGCCGGAGGAGAACAAGAGGACGCGGACGGCCTACACGAGGGCTCAGCTGCTGGAGCTGGAGAAG
GAGTTTCTCTTCAACAAGTACATCTCCCGACCGAGGCGGGTGGAGCTGGCCGTCATGTTAAACCTGACCGAGAGACACA
TCAAGATCTGGTTCCAGAACCGACGGATGAAATGGAAGAAAGAAGAAGACAAAAAGCGGGGGACGGCCAACAGCGCTGA
TCCCGAGCAGGACTGCGTCGTGTCCTCCGGGAAGCTGCAGGGCAAAGAGGATCTGCAGCCGTGA
CitationKumar M, Jordan N, Melton D, Grapin-Botton A. Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate. Dev Biol. 2003 Jul 1;259(1):109-22.
CopyrightCopyright © 2003 Elsevier Science (USA). All rights reserved.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_001234635).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-23
stage 23
stage 23
Duodenum
Pancreas
 

Mouse

EmageMGI:102851
EurexpressMGI:102851
MGI GXDMGI:102851

Frog

Xenbase483330

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-990415-122
Home | Contact
     
© 2008 Arizona Board of Regents
This website is hosted by the Biotechnology Computing Facility at the University of Arizona