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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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ADAM10
ADAM metallopeptidase domain 10

Gene

Official Symbol	ADAM10
Official Full Name	ADAM metallopeptidase domain 10
CGNC ID	3093
also known as	disintegrin and metalloproteinase domain-containing protein 10\|a disintegrin and metalloproteinase domain 10
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204261
Polypeptide	NP_989592

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	43501			FBgn0039688
Human	102			MIM:602192
Mouse	11487	ENSMUSG00000054693	All phenotypic alleles (8):Targeted, knock-out(2) Targeted, other(6)	MGI:109548
Xenopus	733451, 399187			945387
Zebrafish	393392, 566044	ENSDARG00000015502, ENSDARG00000053468	ZDB-GENE-040917-2, ZDB-GENE-071115-1, ZDB-GENE-030131-2297	ZFIN:ZDB-GENE-040917-2, ZFIN:ZDB-GENE-071115-1, ZFIN:ZDB-GENE-030131-2297

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	374113
Ensembl Gene	ENSGALG00000004212
KEGG	gga:374113

Entry 1

GEISHA Id	ADAM10.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	GAAATGATTCGGACTGTGCGAG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTGTCTCCAATGCTGAGGTGGTC	cDNA Template Length	1074
Forward cDNA Template Probe	show `TAGCCTCCTNGCCTGTCTGGCAGTTGAAAAATATATATTTTTTCAATTCTTGAATAAAAGTTTTACTACAGCCATATTT GCCTGCAAGTGAAGAAAATGCAGCAATGAAGAGCACAGGAGGGAGAAAGAATCATGATGCTCTAGGATTTTGTGCCACT AAATTAAAAGTATGCAAGAAAAACATTTTTCTTCTTTTTGAGCTGGAAGATTCACTCATCGTAAAATTCACCATTCCCA CTTGTTTTGAGGGCAAGTCATGCTTTTTTTTTTCCCTCCATTTTTGNNTTAAACNGGGGNCNANGGNTTNTTAGGNTTT TCNTTGGNNGGGGTTTTCCCCTTGGAGGN`

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Unlabeled

7-12

stage 8

stage 9

stage 11

Anterior Intestinal Portal
Blood Islands
Dermomyotome
Ectoderm
Extraembryonic Mesoderm
Forebrain
Foregut
Head Mesenchyme
Heart
Intermediate Mesoderm
Lateral Plate Mesoderm
Neural Plate/Tube
Notochord
Pharynx
Sinus Venosus
Somites
extraembryonic ectoderm
extraembryonic endoderm

13-18

stage 17

Amnion
Dermomyotome
Ear/Otic Placode
Eye
Forebrain
Foregut
Heart
Hindbrain
Leg Mesenchyme
Lung
Midbrain
Notochord
Oral Pharynx
Pharyngeal Arches and Clefts
Spinal Cord
Wing Mesenchyme

19-24

stage 19

stage 22

stage 23

Allantois
Amnion
Dermatome
Dermomyotome
Ear/Otic Placode
Endoderm
Eye
Forebrain
Foregut
Heart
Hindbrain
Hindgut
Leg Mesenchyme
Liver
Lung
Mesonephros
Midbrain
Nephric Ducts
Notochord
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Splanchnic Mesoderm
Widespread Expression
Wing Mesenchyme

25-27

stage 27

Atria
Dermomyotome
Duodenum
Endocardium
Forebrain
Foregut
Gizzard
Heart
Hindbrain
Hindgut
Leg Mesenchyme
Liver
Lung
Mesonephros
Midbrain
Myotome
Outflow Tract
Pharyngeal Arches and Clefts
Proepicardium
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Splanchnic Mesoderm
Widespread Expression
Wing Mesenchyme

Entry 2

GEISHA Id	ADAM10.Yan.2011	Data Source	Publication
Complete cDNA Template Probe	show ATGGATCTAGCGAGGACGATAATCCTGCTGTGCTCCTGGGCGGCGGGCGCCGGAGGCCAGTATGGAAATCCTCTAAATA AATACATTAGACATTATGAAGGATTATCTTACGATGTGGATTTGTTACACCAAAAACACCAGCGTGCCAAAAGAGCAGT ATCGCATGAAGATCAGTTCTTGCGCCTCGACTTTCATGCTCATGGAAGACAATTCAACCTTCGAATGAAGAGAGATACA TCTCTTTTTAGTGAGGACTTTAAAGTAGAAACATCAAACCAAGTAATCGATTATGATACCTCCCATATTTACACTGGAC ACATTTATGGTGAGCAGGGAAGTTTTAGCCATGGGTCTGTTATTGATGGAAGATTTGAAGGATTCATCCAAACTCACAG TGGGACCTTTTATGTTGAGCCAGCAGAGAGATATATTAAGGACAGAACTCTACCGTTCCACTCTGTCATCTATCATGAA GATGATATCAAATATCCTCATAAATATGGACCACAAGGAGGTTGTGCAGATCATTCAGTGTTTGAAAGAATGCAGAAGT ACCAGATGACTGGTATAGAAGAACCAACAACAGAGAAGCCTTCTGAAGAGTCTGACAGCGACGGTCCTCAGCTTTTAAG AAAAAAACGTGCCACTCAAGCTGAAAAAAACACTTGTCAGCTGTATATTCAGACTGATCATCTGTTCTATAAACACTAT GGAACAAGGGAAGCTGTAATTGCACAGATATCCAGCCATGTTAAAGCAATTGACACAATTTACCGCTCAACAGATTTCT CAGGAATCCGTAACATCAGCTTTATGGTGAAGCGAATAAGAATTAACACAACTGTAGATGAGAAGGACCCTTCAAATCC CTTCAGGTTTCCTAACATTGGTGTGGAAAAGTTTCTGGAACTGAACTCAGAACAGAATCATGATGATTATTGTTTGGCC TATGTATTTACGGACCGTGATTTTGATGATGGAGTCCTTGGTCTGGCTTGGGTTGGAGCCCCTTCAGGAAGCTCTGGTG GGATATGTGAAAAGAGCAAACTGTATTCTGATGGTAAGAAGAAGTCTTTGAACACTGGAATCATCACTGTTCAGAACTA TGGCTCTCATGTTCCTCCCAAGGTTTCGCATATCACTTTTGCTCATGAGGTTGGACATAACTTTGGCTCACCTCATGAT TCTGGAATGGAATGCACTCCAGGGGAGTCCAAGAACTTGGGACAGAAAGAAAATGGGAATTACATCATGTATGCAAGAG CTACATCTGGGGACAAACTTAATAACAACAAGTTCTCACTCTGTAGTATTCGAAATATCAGCCAAGTTCTTGAGAAAAA GAGAAATAACTGCTTTGTTGAGTCTGGTCAACCTATCTGTGGTAATGGACTGGTAGAAGAAGGAGAGCAGTGTGATTGT GGATACAGTGATCAGTGTAAAGATGAATGCTGTTACGATGCAAACCAATCAGATGATAAAAAATGCAAGTTAAAACCAG GCAAATCCTGCAGCCCTAGCCAAGGCCCTTGCTGTACTGCGCAATGTAATTTCAAACTGAAGACTGATAAGTGCCGAAA TGATTCGGACTGTGCGAGGGAGGGAATGTGTAATGGTTACAGTGCTCTCTGTCCTGCCTCTCAGCCTAAACAGAACTTC ACAGAATGCAACAGGCGTACACAAGTTTGCATAAAAGGGCAATGTACTGGCTCTATCTGTGAGAAGTACGACTTGGAGG AATGCACATGCGCTAGTTCGGATGGCAAGGATGACAGAGAACTGTGTCATGTCTGCTGCATGAGAAAAATGGACCCGGA TACTTGTGCAAGCACGGGCTCCAGCCGCTGGGAGAAACACTTTGCTCGTAAAACTATTACGTTGCAACCAGGATCTCCT TGTAATGATTTCAGAGGCTACTGTGATGTGTTTATGAGATGTCGGCTGGTAGATGCTGATGGCCCTCTAGCTCGGTTAA AGAAAGCCATTTTTAATCCTGAGCTGTATGAAAATATTGCAGAATGGATCGTGGCTCATTGGTGGGCAGTATTGCTTAT GGGAATTGCCCTGATCATGTTAATGGCTGGTTTCATTAAGATATGCAGTGTTCATACTCCAAGCAGTAATCCAAAGTTG CCTCCTCATAAACCACTTCCAGGCACTTTAAAAAGGAGGAGACCGCCACAAACTGCTCAGCCACCACAGCGACAAAGGC CCCGAGAGAGCTATCAGATGGGACATATGAGACATTGA
Citation	Yan X, Lin J, Rolfs A, Luo J. Differential expression of the ADAMs in developing chicken retina. Dev Growth Differ. 2011 Jun;53(5):726-39.
Copyright	copyright 2011 The Authors
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204261).

Stage

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Location (click to highlight)

Comments (click to highlight)

25-30

stage 27

Retina

31-44

stage 31

stage 35

stage 38

stage 40

stage 42

stage 44

Retina

Entry 3

GEISHA Id	ADAM10.Lin.2010B	Data Source	Publication
Complete cDNA Template Probe	show ATGGATCTAGCGAGGACGATAATCCTGCTGTGCTCCTGGGCGGCGGGCGCCGGAGGCCAGTATGGAAATCCTCTAAATA AATACATTAGACATTATGAAGGATTATCTTACGATGTGGATTTGTTACACCAAAAACACCAGCGTGCCAAAAGAGCAGT ATCGCATGAAGATCAGTTCTTGCGCCTCGACTTTCATGCTCATGGAAGACAATTCAACCTTCGAATGAAGAGAGATACA TCTCTTTTTAGTGAGGACTTTAAAGTAGAAACATCAAACCAAGTAATCGATTATGATACCTCCCATATTTACACTGGAC ACATTTATGGTGAGCAGGGAAGTTTTAGCCATGGGTCTGTTATTGATGGAAGATTTGAAGGATTCATCCAAACTCACAG TGGGACCTTTTATGTTGAGCCAGCAGAGAGATATATTAAGGACAGAACTCTACCGTTCCACTCTGTCATCTATCATGAA GATGATATCAAATATCCTCATAAATATGGACCACAAGGAGGTTGTGCAGATCATTCAGTGTTTGAAAGAATGCAGAAGT ACCAGATGACTGGTATAGAAGAACCAACAACAGAGAAGCCTTCTGAAGAGTCTGACAGCGACGGTCCTCAGCTTTTAAG AAAAAAACGTGCCACTCAAGCTGAAAAAAACACTTGTCAGCTGTATATTCAGACTGATCATCTGTTCTATAAACACTAT GGAACAAGGGAAGCTGTAATTGCACAGATATCCAGCCATGTTAAAGCAATTGACACAATTTACCGCTCAACAGATTTCT CAGGAATCCGTAACATCAGCTTTATGGTGAAGCGAATAAGAATTAACACAACTGTAGATGAGAAGGACCCTTCAAATCC CTTCAGGTTTCCTAACATTGGTGTGGAAAAGTTTCTGGAACTGAACTCAGAACAGAATCATGATGATTATTGTTTGGCC TATGTATTTACGGACCGTGATTTTGATGATGGAGTCCTTGGTCTGGCTTGGGTTGGAGCCCCTTCAGGAAGCTCTGGTG GGATATGTGAAAAGAGCAAACTGTATTCTGATGGTAAGAAGAAGTCTTTGAACACTGGAATCATCACTGTTCAGAACTA TGGCTCTCATGTTCCTCCCAAGGTTTCGCATATCACTTTTGCTCATGAGGTTGGACATAACTTTGGCTCACCTCATGAT TCTGGAATGGAATGCACTCCAGGGGAGTCCAAGAACTTGGGACAGAAAGAAAATGGGAATTACATCATGTATGCAAGAG CTACATCTGGGGACAAACTTAATAACAACAAGTTCTCACTCTGTAGTATTCGAAATATCAGCCAAGTTCTTGAGAAAAA GAGAAATAACTGCTTTGTTGAGTCTGGTCAACCTATCTGTGGTAATGGACTGGTAGAAGAAGGAGAGCAGTGTGATTGT GGATACAGTGATCAGTGTAAAGATGAATGCTGTTACGATGCAAACCAATCAGATGATAAAAAATGCAAGTTAAAACCAG GCAAATCCTGCAGCCCTAGCCAAGGCCCTTGCTGTACTGCGCAATGTAATTTCAAACTGAAGACTGATAAGTGCCGAAA TGATTCGGACTGTGCGAGGGAGGGAATGTGTAATGGTTACAGTGCTCTCTGTCCTGCCTCTCAGCCTAAACAGAACTTC ACAGAATGCAACAGGCGTACACAAGTTTGCATAAAAGGGCAATGTACTGGCTCTATCTGTGAGAAGTACGACTTGGAGG AATGCACATGCGCTAGTTCGGATGGCAAGGATGACAGAGAACTGTGTCATGTCTGCTGCATGAGAAAAATGGACCCGGA TACTTGTGCAAGCACGGGCTCCAGCCGCTGGGAGAAACACTTTGCTCGTAAAACTATTACGTTGCAACCAGGATCTCCT TGTAATGATTTCAGAGGCTACTGTGATGTGTTTATGAGATGTCGGCTGGTAGATGCTGATGGCCCTCTAGCTCGGTTAA AGAAAGCCATTTTTAATCCTGAGCTGTATGAAAATATTGCAGAATGGATCGTGGCTCATTGGTGGGCAGTATTGCTTAT GGGAATTGCCCTGATCATGTTAATGGCTGGTTTCATTAAGATATGCAGTGTTCATACTCCAAGCAGTAATCCAAAGTTG CCTCCTCATAAACCACTTCCAGGCACTTTAAAAAGGAGGAGACCGCCACAAACTGCTCAGCCACCACAGCGACAAAGGC CCCGAGAGAGCTATCAGATGGGACATATGAGACATTGA
Citation	Lin J, Yan X, Markus A, Redies C, Rolfs A, Luo J.Dev Expression of seven members of the ADAM family in developing chicken spinal cord. Dyn. 2010 Apr;239(4):1246-54.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204261.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 20

stage 24

Dermomyotome
Myotome
Sclerotome
Spinal Cord
Spinal Ganglia and Nerves

ep, epithelial cells of the ventricular layer
epithelial cells of the ventricular layer
floor plate
fp, floor plate
lm, lateral motor neuron column
me, meninges

25-30

stage 29

Spinal Cord
Spinal Ganglia and Nerves

ep, epithelial cells of the ventricular layer
lm, lateral motor neuron column
me, meninges

31-37

stage 34

stage 36

stage 37

Sclerotome
Spinal Cord
Spinal Ganglia and Nerves

dh, dorsal horn
ep, epithelial cells of the ventricular layer
lm, lateral motor neuron column
me, meninges
sg, sympathetic ganglion
vr, ventral root

Entry 4

GEISHA Id	ADAM10.Lin.2008	Data Source	Publication
Complete cDNA Template Probe	show ATGGATCTAGCGAGGACGATAATCCTGCTGTGCTCCTGGGCGGCGGGCGCCGGAGGCCAATATGGAAATCCTCTAAATA AATACATTAGACATTATGAAGGATTATCTTATGATGTGGATTTGTTACACCAAAAACACCAGCGTGCCAAAAGAGCAGT ATCGCATGAAGATCAGTTCTTGCGCCTCGACTTTCATGCTCATGGAAGACAATTCAACCTTCGAATGAAGAGAGATACA TCTCTTTTTAGTGAGGACTTTAAATTAGAAACATCAAACCAAGTAATTGATTATGATACCTCCCATATTTACACTGGAC ACATTTATGGTGAGCAGGGAAGTTTTAGCCATGGGTCTGTTATTGATGGAAGATTTGAAGGATTCATCCAAACTCACAG TGGGACCTTTTATGTTGAGCCAGCAGAGAGATATATTAAGGACAGAACTCTACCGTTCCACTCTGTCATCTATCATGAA GATGATATCAAATATCCTCATAAATATGGACCACAAGGAGGTTGTGCAGATCATTCAGTGTTTGAAAGAATGCAGAAGT ACCAGATGACTGGTATAGAAGAACCAACAACAGAGAAGCCTTCTGAAGAGTCTGACAGCGACGGTCCTCAGCTTTTAAG AAAAAAACGTGCCACTCAAGCTGAAAAAAACACTTGTCAGCTGTATATTCAGACTGATCATCTGTTCTATAAACACTAT GGAACAAGGGAAGCTGTAATTGCACAGATATCCAGCCATGTTAAAGCAATTGACACAATTTACCGCTCAACAGATTTCT CAGGAATCCGTAACATCAGCTTTATGGTGAAGCGAATAAGAATTAACACAACTGTAGATGAGAAGGACCCTTCAAATCC CTTCAGGTTTCCTAACATTGGTGTGGAAAAGTTTCTGGAACTGAACTCAGAACAGAATCATGATGATTATTGTTTGGCC TATGTATTTACGGACCGTGATTTTGATGATGGAGTCCTTGGTCTAGCTTGGGTTGGAGCCCCTTCAGGAAGCTCTGGTG GGATATGTGAAAAGAGCAAACTGTATTCTGATGGTAAGAAGAAGTCTTTGAACACTGGAATCATCACTGTTCAGAACTA TGGCTCTCATGTTCCTCCCAAGGTTTCGCATATCACTTTTGCTCATGAGGTTGGACATAACTTTGGCTCACCTCATGAT TCTGGAATGGAATGCACTCCAGGGGAGTCCAAGAACTTGGGACAGAAAGAAAATGGGAATTATATCATGTATGCAAGAG CTACATCTGGGGACAAACTTAATAACAACAAGTTCTCACTCTGTAGTATTCGAAATATCAGCCAAGTTCTTGAGAAAAA GAGAAATAACTGCTTTGTTGAGTCTGGTCAACCTATCTGTGGTAATGGACTGGTAGAAGAAGGAGAGCAGTGTGATTGT GGATACAGTGATCAGTGTAAAGATGAATGCTGTTACGATGCAAACCAATCAGATGATAAAAAATGCAAGTTAAAACCAG GCAAATCCTGCAGCCCTAGCCAAGGCCCTTGCTGTACTGCGCAATGTAATTTCAAACTGAAGACTGATAAGTGCCGAAA TGATTCGGACTGTGCGAGGGAGGGAATGTGTAATGGTTACAGTGCTCTCTGTCCTGCCTCTCAGCCTAAACAGAACTTC ACAGAATGCAACAGGCGTACACAAGTTTGCATAAAAGGGCAATGTACTGGCTCTATCTGTGAGAAGTACGACTTGGAGG AATGCACATGCGCTAGTTCAGATGGCAAGGATGACAGAGAACTGTGTCATGTCTGCTGCATGAGAAAAATGGACCCGGA TACTTGTGCAAGCACGGGCTCCAGCCGCTGGGAGAAACACTTTGCTCGTAAAACTATTACGTTGCAACCAGGATCTCCT TGTAATGATTTCAGAGGCTACTGTGATGTGTTTATGAGATGTCGGCTGGTAGATGCTGATGGCCCTCTAGCTCGGTTAA AGAAAGCAATTTTTAATCCTGAGCTGTATGAAAATATTGCAGAATGGATCGTGGCTCATTGGTGGGCAGTATTGCTTAT GGGAATTGCCCTGATCATGTTAATGGCTGGTTTCATTAAGATATGCAGTGTTCATACTCCAAGCAGTAATCCAAAGTTG CCTCCTCATAAACCACTTCCAGGCACTTTAAAAAGGAGGAGACCGCCACAAACTGCTCAGCCACCACAGCGACAAAGGC CCCGAGAGAGCTATCAGATGGGACATATGAGACATTGA
Citation	Lin J, Luo J, Redies C. Differential expression of five members of the ADAM family in the developing chicken brain. Neuroscience. 2008 Nov 19;157(2):360-75. doi: 10.1016/j.neuroscience.2008.08.053. Epub 2008 Sep 4.
Copyright	Copyright © 2008 IBRO. Published by Elsevier Ltd. All rights reserved.