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Human Disease Gene Search
CTSD The human orthologue of this gene is associated
Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol CTSD Official Full Name cathepsin D CGNC ID 4989 also known as cathepsin D|cathepsin D (lysosomal aspartyl peptidase)|cathepsin D (lysosomal aspartyl protease)|prepro-cathepsin D, prepro-CD, Cathepsin D precursor , Cathepsin D light chain; Cathepsin D heavy chain gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Links to other databases
Entry 1 GEISHA Id CTSD.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer 5’-CATCTTGGGCATGGCATTCC-3’ Reverse cDNA Template Primer 5’-AATTAACCCTCACTAAAGGGGCGCTTAGACACATTTGGC-3’ cDNA Template Length 648 Complete cDNA Template Probe show CATCTTGGGCATGGCATTCCCAAGAATCTCTGTGGACAAGGTCACACCTTTCTTTGATAATGTCATGCAGCAGAAGCTG
Entry 2 GEISHA Id CathepsinD.Zuzarte-Luis.2007b Data Source Publication Complete cDNA Template Probe show TTCTGCGCTTCTGCTTTAGGGGGTGTAGTGCGTTGTAAGCGTTCCGCCGCTATGGCGCCCCGCGGCCTTCTCGTCCTGC
Citation Zuzarte-Luis V, Montero JA, Torre-Perez N, Garcia-Porrero JA, Hurle JM. Cathepsin D gene expression outlines the areas of physiological cell death during embryonic development. Dev Dyn. 2007 Mar;236(3):880-5. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Authors said: For in situ hybridization, antisense probes for cathepsin D, B, and L (Zuzarte-Luis et al.,[2007]), where they said:cCatDfwd: 5′-TTC TGC GCT TCT GCT TTA GGG-3′ and rev: 5′-TGA GTG GGT TTC TAA TCC TGA-3. The sequences presented was excerpted from the full length using these sequences.
Entry 3 GEISHA Id CTSD.Gammill.2002 Data Source Publication Complete cDNA Template Probe show GGGGCCCCGTCAGCTGACGCTCCGTGCCGGGCCTGAGGCCGCCGCTACAAAAGCGGGGTGGCAGGCGAGGCGGGTTCTG
Citation Gammill LS, Bronner-Fraser M. Genomic analysis of neural crest induction. Development. 2002 Dec;129(24):5731-41. Copyright Published by The Company of Biologists 2002. This material is protected by a copyright retained by the authors. Permission granted by Dr. Bronner-Fraser.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
Neural Crest
Entry 4 GEISHA Id CathepsinD.Zuzarte-Luis.2007a Data Source GEISHA ISH Analysis Complete cDNA Template Probe show TTCTGCGCTTCTGCTTTAGGGGGTGTAGTGCGTTGTAAGCGTTCCGCCGCTATGGCGCCCCGCGGCCTTCTCGTCCTGC
Comments Authors indicated probes were derived using these primers:for cCatDfwd: 5′-TTC TGC GCT TCT GCT TTA GGG-3′ and rev: 5′-TGA GTG GGT TTC TAA TCC TGA-3′ probe was extracted from NCBI acc# NM_205177.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 21
Leg 31-33 stage 31
stage 32
stage 32
stage 33
stage 33
Leg
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