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TARDBP
TAR DNA binding protein

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	TARDBP
Official Full Name	TAR DNA binding protein
CGNC ID	2099
also known as	TAR DNA-binding protein 43\|TDP-43, TAR DNA binding protein, TARDBP
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	37781			FBgn0025790
Human	23435		MIM:612069	MIM:605078
Mouse	230908	ENSMUSG00000041459	All phenotypic alleles (6):Targeted, knock-out(3) Targeted, other(2) Gene trapped(1)	MGI:2387629
Xenopus	394651, 380329			974452
Zebrafish	325052	ENSDARG00000040031	ZDB-GENE-030131-3777	ZFIN:ZDB-GENE-030131-3777

Gene Ontology

Molecular Function	DNA binding, RNA binding, nucleotide binding
Biological Process	RNA splicing, mRNA processing, regulation of transcription, DNA-templated, transcription, DNA-templated
Cellular Component	nucleus

Links to other databases

GEISHA Id	ChEST412l6	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show CTCATACTGACTCTTTGGTGGGAAATCAAATTTTTCTAACGCGTGTTCATCTCATTTCAAATGTGTATGGAAGAAGCAC TTCATTGAAAGCAGTGCTGTAAATATTCTGCCTTAGGAATACTTCTGTCTACATGCTTTCTCATCCAAGAATACTTCAT CACACTGCACATGCTGCGTCTTAGACGGTGGGTGTTCCATTTTTATCCGCTACTCTTTATTTCATGGAGTCGTATCAAC GCTATGAACGCAAGGCTGTGAGATGGAACCAGAAGGCTGTTTGAACTTTTGAAACCTTGTGTGGGATTGATGGTGGTGC CGAGGCATGAGAGGGCTGGTATGAGCGAGAAAAAAGAGAGCGCATGCGGAGACCTGGTGGTGCATTATGGGATTTTATT TTACTTGGCGAGATGTCTCTCAATCCTGTGGCTTTGGTGAGAGAGTGTGCAGAGCGCAATGATAGCAAATAAAGTACGA GTGTTTATTGCATTCAAAGGACATCCATACGTGGAAGACTTTAAGTGGGTTTTATACCTAGTTAATCAATTAGCTGAAT GTGTTTATGTGAAAAGAATATTTGTATTTTTTTTCCCTTATGTCAACTGCTGTGAATGCTGTATGGTGTGTGTTGTTTT TTTTTTTCTGTTAATGATCTGTAAGTGTGGCAATGTGAATTGAAGATGGTGGGGTTTGCGATGAGACCATTGGGCTTGT GATGTGCTTTGCAGTAGCTCTTGCAGCGCATCACTGGTGAGCTCAGTGTGCCTCTTGAGGGTGGAAGCTCTGCTGTGTA AGATACCATAAGAATGCTGTTTGCTGCAGTTCCGTGTTTGGATGCTTTTTATAAGATTTGTCACTGTAGGAAATCTTAA ATAAAACTGATTCGT
Comments	No specific expression detected at stage 12, widespread at stage 15 and 18.