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Human Disease Gene Search
SIX1 The human orthologue of this gene is associated
Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol SIX1 Official Full Name SIX homeobox 1 CGNC ID 54357 also known as homeobox protein SIX1|sine oculis homeobox homolog 1 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id SIX1.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer GGAGAACACGGAGAACAACAACG Reverse cDNA Template Primer AATTAACCCTCACTAAAGGGAGGCAGACAGAGAGAGACGC cDNA Template Length 944 Forward cDNA Template Probe show CCCANNCCCCNCCNNNCCCCCCCGCCCTCTCCCTTCATTTTATTTCTGCTGCTGTAATTCCCCCTCACTTGAACTCAAA
Entry 2 GEISHA Id Six1.Barembaum.2007 Data Source Publication Complete cDNA Template Probe show GCCGAGCATCCCCCGCTCCGCCGCCGCGGCCGCCTCCGCGCCTCCCCGCTCTGGGGACGGGACCGGGCCCGGGGCTCTC
Citation Barembaum M, Bronner-Fraser M. Spalt4 mediates invagination and otic placode gene expression in cranial ectoderm. Development. 2007 Nov;134(21):3805-14. Copyright Published by The Company of Biologists 2007 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001044685).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 4-6 stage 5
stage 5
Ectoderm 13 stage 13
Ear/Otic Placcode
Entry 3 GEISHA Id SIX1.Sato.2012 Data Source Publication Complete cDNA Template Probe show GCCGAGCATCCCCCGCTCCGCCGCCGCGGCCGCCTCCGCGCCTCCCCGCTCTGGGGACGGGACCGGGCCCGGGGCTCTC
Citation Sato S, Ikeda K, Shioi G, Nakao K, Yajima H, Kawakami K.
Regulation of Six1 expression by evolutionarily conserved enhancers in tetrapods. Dev Biol. 2012 Aug 1;368(1):95-108. doi: 10.1016/j.ydbio.2012.05.023. Epub 2012 May 30.
Copyright Copyright © 2012 Elsevier Inc. Comments The sequence below was obtained from NCBI (acc # AB199734.1) using the information provided in the publication as described in Sato et al.
Entry 4 GEISHA Id SIX1.Litsiou.2005 Data Source Publication Complete cDNA Template Probe show GCCGAGCATCCCCCGCTCCGCCGCCGCGGCCGCCTCCGCGCCTCCCCGCTCTGGGGACGGGACCGGGCCCGGGGCTCTC
Citation Litsiou A, Hanson S, Streit A. A balance of FGF, BMP and WNT signalling positions the future placode territory in the head. Development. 2005 Sep;132(18):4051-62. Epub 2005 Aug 10 Copyright Authors hold the copyright. Published by the Company of Biologists Ltd. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_001044685.1
Entry 5 GEISHA Id SIX1.Anderson.2019 Data Source Publication Complete cDNA Template Probe show AAAGTTCCCCCCGGCGCTCCGCCGAGCATCCCCCGCTCCGCCGCCGCGGCCGCCTCCGCGCCTCCCCGCTCTGGGGACG
Citation Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5. Copyright Copyright © 2019 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001044685 ).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Heart
Mouse Frog Fruit Fly Zebra Finch Zebrafish
