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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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CDKN1B
cyclin dependent kinase inhibitor 1B

Gene

Official Symbol	CDKN1B
Official Full Name	cyclin dependent kinase inhibitor 1B
CGNC ID
also known as	cyclin-dependent kinase inhibitor 1B\|cyclin-dependent kinase inhibitor 1B (p27, Kip1)
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204256
Polypeptide	NP_989587

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	1027	ENSG00000111276		MIM:600778
Mouse	12576	ENSMUSG00000003031		MGI:104565
Xenopus	492306			6492273
Zebrafish	368329, 402862	ENSDARG00000054271	ZDB-GENE-030521-13, ZDB-GENE-040812-3	ZFIN:ZDB-GENE-030521-13, ZFIN:ZDB-GENE-040812-3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	374106
Ensembl Gene	ENSGALG00000022980
KEGG	gga:374106

Entry 1

GEISHA Id	CDKN1B.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	5'-TTCAGTGGAGCAAACACCCAAG-3'
Reverse cDNA Template Primer	5'-AATTAACCCTCACTAAAGGTGGAGATTCGGAACAAGTGCC-3'	cDNA Template Length	741
Complete cDNA Template Probe	show TTCAGTGGAGCAAACACCCAAGAAATCGAGCCCGAGACGACATCAAACGTAAACTCCCTAAGGCGGAGGACTCGCGTTT CCTTGCTCATCGGGGGGCGGTGAAGCCAGGAAGATATAAAGTTGTAGTAGAGATGAATACATATCGTCGGTCTCCATGG GATGGGGACCCTGTGCAAGCACTGAAAAACAACGACAGCAAAACAAAAAAAAAAGCAGACAATAACACTAAAAGTTTAG ACACTCTTAAAAGACCTGCCTCTAAAAGCATCGGATGTAGCATTGTGCAATTAGGTGTTTCCTTATTTGCTTCATTGTA CTACCTGTGTATATAGTTTTTACCTTATGTAGCACATAAACGTTTTGGGAGGGGGGGGAGTGGAAGAGGGCGACCGATG GAAACTTGCTTTCGCCATCTAGCAAGCAAAGAAATGAAGAGAAGCAGTGTAGGCTCTTTATTCCTTAAAGATGTATTGT CCCTTTAAGTGGGTCCCCTGTGTTTTTATTTTTTCCTCGCAACACGGTGGTAGCGCTGCTCGCAGCAGATGCCTGCAGG CCGCCGTCAGAGCCCTCTTCGCTGTGCTGGGCTGAAGGGGTGGGAGGTGGGGTGATCCCCCCACCTCAGATCCCTATAG GAAATTGGAATGCCTCTAGTCTCACAAATTCACCCCATTTGCTACATCGCCGGAGTTGTTATTTTTATTTTTGGAAAGG AATCCGGAGGGCACTTGTTCCGAATCTCCA

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Unlabeled

7-12

stage 8

stage 9

stage 11

Blood Islands
Forebrain
Hindbrain
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Sinus Venosus
Somites
Unlabeled
Ventricles
extraembryonic mesoderm

13-18

stage 13

stage 16

stage 18

Amnion
Blood Islands
Dermomyotome
Eye
Forebrain
Foregut
Head Mesenchyme
Heart
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Leg Mesenchyme
Liver
Lung
Midbrain
Myotome
Neural Plate/Tube
Notochord
Outflow Tract
Pharyngeal Arches and Clefts
Proepicardium
Sclerotome
Sinus Venosus
Somatic Mesoderm
Somites
Tail
Ventricles
Wing Mesenchyme
extraembryonic mesoderm

19-24

stage 20

stage 21

Eye
Forebrain
Foregut
Head Mesenchyme
Hindbrain
Leg Mesenchyme
Lung
Midbrain
Myotome
Neural Plate/Tube
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Sinus Venosus
Ventricles
Wing Mesenchyme

25-26

stage 26

Forebrain
Foregut
Head Mesenchyme
Hindbrain
Lateral Plate Mesoderm
Leg Mesenchyme
Liver
Lung
Mesonephros
Midbrain
Myotome
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Sinus Venosus
Spinal Cord
Ventricles
Widespread Expression
Wing Mesenchyme

Entry 2

GEISHA Id	p27kip1.Pickering.2019	Data Source	Publication
Complete cDNA Template Probe	show GCGCCGACGGGGCGGTGCCGGCCGCCGTAACCAATGGCTCGGCTCCGCTGTTTAAATAGACTCGTCCTGTCAATCATTT TCTCCTTCGTCAACCTCCCTTCAATCGCCATATTGGGCAACTGAGAAAAGGGCTCGTCTCGCCTTGTTTTTTTTCCCTC TCCGCCCGTACGACGTGGCCGTGGGGAGAGCGGCGGGGCCGTGCGGACAGCGGCGGGGCCGTGCGGATAGCAGCGCGAG GCCGCCCCCGGGGCCGCGGAGGGCAGCGCCGCTCCCCGCTCGGCTGCTCCCCTCCGGAGCCGCCCGGGCTGCCCGGCGG CGGCTGTCGGGGTTCGGCCGGCCCGGCGCTTATGCAATTGCGCGCTGCCGCCTCTCCTCCGCGGGCCGAGGCGGGGCCG CAGAGAGGGGGCCGTACGGAGAGAGACCGCGGAGGAGAACCTGCGAGCGGCCGCGGGTAAGAAGCGGAGAGGAAGAGCG GGGAGAGCCGCGAGAAAACCCACCGCCATCGGTGACGGCAGAAAGGGAGGGGGAGATGTCAAACGTCCGCATTTCTAAT GGGAGCCCTACCCTGGAGCGCATGGAGGCGCGGCAGTCGGAGTACCCGAAGCCGTCGGCCTGCAGGAACCTCTTCGGGC CGGTAAACCACGAAGAGTTAAACAGGGACTTGAAGAAGCACCGCAAGGAAATGGAAGAGGCATGCCAGAGGAAGTGGAA TTTCGATTTCCAGAACCACAAGCCGCTGGAAGGCAGGTACGAGTGGCAAGCCGTGGAGAAGGGGAGCTCGCCCGACTTC TACTTCAGGCAGCCGAGGCTATCCAAAGCCGTCTGCAAGTCCGCCGGCCGTCAGAGCCTGGATGTAAACGGGAATTGCC AAACCGCGATTTGCGCCGCTTCTCAGGGAATCTCAGAGGACACTCACTGTGTAGGCCGAAAGACTGATGTTGCTGGCAG TCAGACGGACTTTGCAGAGCAGTGCGCCGGGCAGAGGAAAAGACCCGCCGCCGACGATTCCTCTCCTCAAAATAAAAGA GCCAACACAACAGAAGAGGAGGTTTCAGAAGACTCCCCCAGTGCCAGTTCAGTGGAGCAAACACCCAAGAAATCGAGCC CGAGACGACATCAAACGTAAACTCCCTAAGGCGGAGGACTCGCGTTTCCTTGCTCATCGGGGGGCGGTGAAGCCAGGAA GATATAAAGTTGTAGTAGAGATGAATACATATCGTCGGTCTCCATGGGATGGGGACCCTGTGCAAGCACTGAAAAACAA CGACAGCAAAACAAAAAAAAAAGCAGACAATAACACTAAAAGTTTAGACACTCTTAAAAGACCTGCCTCTAAAAGCATC GGATGTAGCATTGTGCAATTAGGTGTTTCCTTATTTGCTTCATTGTACTACCTGTGTATATAGTTTTTACCTTATGTAG CACATAAACGTTTTGGGAGGGGGGGGAGTGGAAGAGGGCGACCGATGGAAACTTGCTTTCGCCATCTAGCAAGCAAAGA AATGAAGAGAAGCAGTGTAGGCTCTTTATTCCTTAAAGATGTATTGTCCCTTTAAGTGGGTCCCCTGTGTTTTTATTTT TTCCTCGCAACACGGTGGTAGCGCTGCTCGCAGCAGATGCCTGCAGGCCGCCGTCAGAGCCCTCTTCGCTGTGCTGGGC TGAAGGGGTGGGAGGTGGGGTGATCCCCCCACCTCAGATCCCTATAGGAAATTGGAATGCCTCTAGTCTCACAAATTCA CCCCATTTGCTACATCGCCGGAGTTGTTATTTTTATTTTTGGAAAGGAATCCGGAGGGCACTTGTTCCGAATCTCCAAT GTTGCTGTTTTCTGACCAGGCCCACATCCTTTCGTCCTTGTGTGAGGGAAAGGGATACTACATCTTTAAACAGTATTTC TACATTGCCTGTGTACCTGTATGTAAAAATAAAAAGTTTGAAGTGTAAAAAAAAAAAAAAAA
Citation	Pickering J, Chinnaiya K, Towers M. An autoregulatory cell cycle timer integrates growth and specification in chick wing digit development. Elife. 2019 Sep 23;8. pii: e47625. DOI: 10.7554/eLife.47625.
Copyright	Copyright © 2019, Pickering et al.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_204256.2).

Stage

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Location (click to highlight)

Comments (click to highlight)

19-24

stage 21

stage 22

Somites
Spinal Cord
ZPA

25-27

stage 25

stage 27

Somites
Wing Mesenchyme
ZPA

all

Entry 3

GEISHA Id	p27.Olivera-Martinez.2014	Data Source	Publication
Complete cDNA Template Probe	show GCGCCGACGGGGCGGTGCCGGCCGCCGTAACCAATGGCTCGGCTCCGCTGTTTAAATAGACTCGTCCTGTCAATCATTT TCTCCTTCGTCAACCTCCCTTCAATCGCCATATTGGGCAACTGAGAAAAGGGCTCGTCTCGCCTTGTTTTTTTTCCCTC TCCGCCCGTACGACGTGGCCGTGGGGAGAGCGGCGGGGCCGTGCGGACAGCGGCGGGGCCGTGCGGATAGCAGCGCGAG GCCGCCCCCGGGGCCGCGGAGGGCAGCGCCGCTCCCCGCTCGGCTGCTCCCCTCCGGAGCCGCCCGGGCTGCCCGGCGG CGGCTGTCGGGGTTCGGCCGGCCCGGCGCTTATGCAATTGCGCGCTGCCGCCTCTCCTCCGCGGGCCGAGGCGGGGCCG CAGAGAGGGGGCCGTACGGAGAGAGACCGCGGAGGAGAACCTGCGAGCGGCCGCGGGTAAGAAGCGGAGAGGAAGAGCG GGGAGAGCCGCGAGAAAACCCACCGCCATCGGTGACGGCAGAAAGGGAGGGGGAGATGTCAAACGTCCGCATTTCTAAT GGGAGCCCTACCCTGGAGCGCATGGAGGCGCGGCAGTCGGAGTACCCGAAGCCGTCGGCCTGCAGGAACCTCTTCGGGC CGGTAAACCACGAAGAGTTAAACAGGGACTTGAAGAAGCACCGCAAGGAAATGGAAGAGGCATGCCAGAGGAAGTGGAA TTTCGATTTCCAGAACCACAAGCCGCTGGAAGGCAGGTACGAGTGGCAAGCCGTGGAGAAGGGGAGCTCGCCCGACTTC TACTTCAGGCAGCCGAGGCTATCCAAAGCCGTCTGCAAGTCCGCCGGCCGTCAGAGCCTGGATGTAAACGGGAATTGCC AAACCGCGATTTGCGCCGCTTCTCAGGGAATCTCAGAGGACACTCACTGTGTAGGCCGAAAGACTGATGTTGCTGGCAG TCAGACGGACTTTGCAGAGCAGTGCGCCGGGCAGAGGAAAAGACCCGCCGCCGACGATTCCTCTCCTCAAAATAAAAGA GCCAACACAACAGAAGAGGAGGTTTCAGAAGACTCCCCCAGTGCCAGTTCAGTGGAGCAAACACCCAAGAAATCGAGCC CGAGACGACATCAAACGTAAACTCCCTAAGGCGGAGGACTCGCGTTTCCTTGCTCATCGGGGGGCGGTGAAGCCAGGAA GATATAAAGTTGTAGTAGAGATGAATACATATCGTCGGTCTCCATGGGATGGGGACCCTGTGCAAGCACTGAAAAACAA CGACAGCAAAACAAAAAAAAAAGCAGACAATAACACTAAAAGTTTAGACACTCTTAAAAGACCTGCCTCTAAAAGCATC GGATGTAGCATTGTGCAATTAGGTGTTTCCTTATTTGCTTCATTGTACTACCTGTGTATATAGTTTTTACCTTATGTAG CACATAAACGTTTTGGGAGGGGGGGGAGTGGAAGAGGGCGACCGATGGAAACTTGCTTTCGCCATCTAGCAAGCAAAGA AATGAAGAGAAGCAGTGTAGGCTCTTTATTCCTTAAAGATGTATTGTCCCTTTAAGTGGGTCCCCTGTGTTTTTATTTT TTCCTCGCAACACGGTGGTAGCGCTGCTCGCAGCAGATGCCTGCAGGCCGCCGTCAGAGCCCTCTTCGCTGTGCTGGGC TGAAGGGGTGGGAGGTGGGGTGATCCCCCCACCTCAGATCCCTATAGGAAATTGGAATGCCTCTAGTCTCACAAATTCA CCCCATTTGCTACATCGCCGGAGTTGTTATTTTTATTTTTGGAAAGGAATCCGGAGGGCACTTGTTCCGAATCTCCAAT GTTGCTGTTTTCTGACCAGGCCCACATCCTTTCGTCCTTGTGTGAGGGAAAGGGATACTACATCTTTAAACAGTATTTC TACATTGCCTGTGTACCTGTATGTAAAAATAAAAAGTTTGAAGTGTAAAAAAAAAAAAAAAA
Citation	Isabel Olivera-Martinez, Nick Schurch, Roman A Li, Junfang Song, Pamela A Halley, Raman M Das, Dave W Burt, Geoffrey J Barton, Kate G Storey. Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo. Development 2014 Aug;141(16):3266-76. Epub 2014 Jul 25. DOI: 10.1242/dev.112623.
Copyright	Copyright © 2014. Published by The Company of Biologists Ltd.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_204256.2).