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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
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SOSTDC1
sclerostin domain containing 1

Gene

Official Symbol	SOSTDC1
Official Full Name	sclerostin domain containing 1
CGNC ID	8208
also known as	WISE, sclerostin domain-containing protein 1\|context-dependent activator and inhibitor of Wnt signalling protein Wise\|wnt-signaling modulator
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204373
Polypeptide	NP_989704

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	25928	ENSG00000171243		MIM:609675
Mouse	66042	ENSMUSG00000036169	All phenotypic alleles (8):Spontaneous(1) Targeted, knock-out(3) Targeted, other(4)	MGI:1913292
Xenopus	100101775, 386733, 398708			478255
Zebrafish	100332581, 550261, 564783	ENSDARG00000068892, ENSDARG00000056021	ZDB-GENE-050417-64, ZDB-GENE-060503-653	ZFIN:ZDB-GENE-050417-64, ZFIN:ZDB-GENE-060503-653

Gene Ontology

Molecular Function
Biological Process	Wnt signaling pathway
Cellular Component	extracellular space

Links to other databases

Entrez Gene	378800
Ensembl Gene
KEGG	gga:378800

Entry 1

GEISHA Id	WISE.Shigetani.2007	Data Source	Publication
Complete cDNA Template Probe	show CACAACTTTACACCTGAATGAATGCCAAGCCTCTCCGAATATAAAAAGGAAACCTTGAAGAGCAATTTCAGAGTTAGCG AGAACGAGCAGAAGAAAAACATTTCATCCGGCTCCGTCAGACAGAGACCAAACCAATCATGCTTCTCTCCGCCATTCAC TTCTACGGCTTACTCCTAGCTTGCACCTTCACGAGAAGCTACTCGGCTTTCAAGAACGATGCCACTGAGATACTTTATT CCCACGTCGTTAAACCTGCCCCTGCGAGCCCGAGCAGCAACAGCACGTTGAACCAAGCCAGGAACGGAGGGAGGCACTA CGCCGGCACGGGCTCCGACCGTAACAATCGCGTTCAAGTTGGCTGCCGGGAACTGCGATCTACCAAGTACATCTCAGAC GGCCAGTGCACCAGCATCAATCCCCTGAAGGAGCTGGTGTGTGCTGGCGAATGCCTCCCCTTGCCGCTCCTGCCCAACT GGATTGGAGGAGGTTATGGAACCAAGTACTGGAGCAGACGGAGCTCGCAAGAGTGGAGATGTGTCAATGACAAAACTCG CACCCAGAGGATCCAGCTGCAGTGCCAGGATGGAAGTATAAGAACCTACAAAATAACTGTGGTCACGGCCTGCAAGTGC AAGCGATACACCAGGCAGCACAACGAGTCCAGCCACAACTTTGAGGGAACCTCTCAAGCAAAGCCTGTCCAGCATCACA AAGAGAGAAAAAGAGCCAGTAAATCCAGCAAACATAGTACAAGTTAGAAGTCAGACGTCCTCTCCTCTCCTGCTCCTCC TGCCAAAACTGAACTCACCTGTAACCATTTGCTTTACAGTTCTGACTGCTTAAAGACAAGTCTGCCATTGCTTTGTTCT CAGATGATACTGCACGCTTATTGTTTTGACCAAAATCAAAAGGGGCATTCTCAGCATATGGACCTTTTTGGGTGACTGT CCAAAAGCTCAAGATGGGCAGTAACACAAGCCTTCTAAACCCTCACTTCAAAGTTTTACATTCCCTCCAGCCACGGAGG CAAAGAAAAGTTGCCATGAATATTCACGGAAGTCTGTTTTGTAAAATGGTGCTTTGTTGTGTGTCTTCACGAGAACAGT TTATTATCACTCCTATCGCCTTCTCTATCGATGTTTTATGAACTTCTGACAACAGCTTACAAATGCAACACCAACTATC TGCTTTCAGATTCATTCTAAGAAAAGAATGCCTTGCATGCTGATCTTTCCCCTCAGTATACCAAAAATGAAAATATGCA TGGCAGCAATCCAAAAGTAACGCGGAACAAACTATTTATTTGTTGTTGTAATTATTTAATGAGCTTTTGTATTATTTTT GTTTAAAAGTGTGCAATCAAAAGACAGATATGACTTCCTTTCCAATTCATTGGTTTCTTTTTTTTTTTGTACAAAAATA AACACTGCTAA
Citation	Shigetani Y, Itasaki N. Expression of Wise in chick embryos. Dev Dyn. 2007 Aug;236(8):2277-84.
Copyright	© British Crown copyright 2007/DERApublished with permission of the Controller of Her Majesty's Stationery Office.
Comments	Insufficient information in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI acc #NM_204373.

Stage

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7-9

stage 9

Surface Ectoderm

Entry 2

GEISHA Id	SOSTDC1.Mou.2011	Data Source	Publication
Complete cDNA Template Probe	show CACAACTTTACACCTGAATGAATGCCAAGCCTCTCCGAATATAAAAAGGAAACCTTGAAGAGCAATTTCAGAGTTAGCG AGAACGAGCAGAAGAAAAACATTTCATCCGGCTCCGTCAGACAGAGACCAAACCAATCATGCTTCTCTCCGCCATTCAC TTCTACGGCTTACTCCTAGCTTGCACCTTCACGAGAAGCTACTCGGCTTTCAAGAACGATGCCACTGAGATACTTTATT CCCACGTCGTTAAACCTGCCCCTGCGAGCCCGAGCAGCAACAGCACGTTGAACCAAGCCAGGAACGGAGGGAGGCACTA CGCCGGCACGGGCTCCGACCGTAACAATCGCGTTCAAGTTGGCTGCCGGGAACTGCGATCTACCAAGTACATCTCAGAC GGCCAGTGCACCAGCATCAATCCCCTGAAGGAGCTGGTGTGTGCTGGCGAATGCCTCCCCTTGCCGCTCCTGCCCAACT GGATTGGAGGAGGTTATGGAACCAAGTACTGGAGCAGACGGAGCTCGCAAGAGTGGAGATGTGTCAATGACAAAACTCG CACCCAGAGGATCCAGCTGCAGTGCCAGGATGGAAGTATAAGAACCTACAAAATAACTGTGGTCACGGCCTGCAAGTGC AAGCGATACACCAGGCAGCACAACGAGTCCAGCCACAACTTTGAGGGAACCTCTCAAGCAAAGCCTGTCCAGCATCACA AAGAGAGAAAAAGAGCCAGTAAATCCAGCAAACATAGTACAAGTTAGAAGTCAGACGTCCTCTCCTCTCCTGCTCCTCC TGCCAAAACTGAACTCACCTGTAACCATTTGCTTTACAGTTCTGACTGCTTAAAGACAAGTCTGCCATTGCTTTGTTCT CAGATGATACTGCACGCTTATTGTTTTGACCAAAATCAAAAGGGGCATTCTCAGCATATGGACCTTTTTGGGTGACTGT CCAAAAGCTCAAGATGGGCAGTAACACAAGCCTTCTAAACCCTCACTTCAAAGTTTTACATTCCCTCCAGCCACGGAGG CAAAGAAAAGTTGCCATGAATATTCACGGAAGTCTGTTTTGTAAAATGGTGCTTTGTTGTGTGTCTTCACGAGAACAGT TTATTATCACTCCTATCGCCTTCTCTATCGATGTTTTATGAACTTCTGACAACAGCTTACAAATGCAACACCAACTATC TGCTTTCAGATTCATTCTAAGAAAAGAATGCCTTGCATGCTGATCTTTCCCCTCAGTATACCAAAAATGAAAATATGCA TGGCAGCAATCCAAAAGTAACGCGGAACAAACTATTTATTTGTTGTTGTAATTATTTAATGAGCTTTTGTATTATTTTT GTTTAAAAGTGTGCAATCAAAAGACAGATATGACTTCCTTTCCAATTCATTGGTTTCTTTTTTTTTTTGTACAAAAATA AACACTGCTAA
Citation	Mou C, Pitel F, Gourichon D, Vignoles F, Tzika A, Tato P, Yu L, Burt DW, Bed'hom B, Tixier-Boichard M, Painter KJ, Headon DJ. Cryptic patterning of avian skin confers a developmental facility for loss of neck feathering. PLoS Biol. 2011 Mar;9(3):e1001028. Epub 2011 Mar 15.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204373.1).