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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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WNT7B
Wnt family member 7B

Gene

Official Symbol	WNT7B
Official Full Name	Wnt family member 7B
CGNC ID	10609
also known as	protein Wnt-7b\|wingless-type MMTV integration site family, member 7B, WNT7B , wingless-type MMTV integration site family, member 7B
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_001037274
Polypeptide	NP_001032351

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	35975			FBgn0004360
Human	7477	ENSG00000188064		MIM:601967
Mouse	22422	ENSMUSG00000022382	All phenotypic alleles (8):Targeted, knock-out(3) Targeted, other(5)	MGI:98962
Xenopus	100145124, 399364			481935
Zebrafish	100148840, 563427	ENSDARG00000071107, ENSDARG00000022858	ZDB-GENE-081006-1, ZDB-GENE-041210-178	ZFIN:ZDB-GENE-081006-1, ZFIN:ZDB-GENE-041210-178

Gene Ontology

Molecular Function	frizzled binding
Biological Process	Wnt signaling pathway, cell fate commitment, lens fiber cell development, neuron differentiation, more...positive regulation of JNK cascade
Cellular Component	extracellular space, proteinaceous extracellular matrix

Links to other databases

Entrez Gene	427937
Ensembl Gene	ENSGALG00000014235
KEGG	gga:427937

Entry 1

GEISHA Id	Wnt7b.vonFrowein.2006	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show GACTGGGATTTAAGCGACACGATCGATTCGACTTTTTGTGCAATTTTTATGGCTCAGTCCATTCCCTAGATCATGCACA GAAACTTTCGGAAGTGGATTTTCTACGTGTTTTTATGCTTTGGAGTCATCTATGTCAAATTAGGAGCTTTGTCATCTGT GGTGGCTTTAGGAGCTAATATCATCTGCAACAAAATCCCAGGCTTGGCCCCTCGGCAGCGAGCAATCTGCCAGAGCCGC CCTGATGCCATCATTGTGATTGGAGAAGGGGCACAAATGGGAATCAATGAGTGCCAGTACCAGTTTCGGTATGGGAGGT GGAACTGCTCTGCGCTGGGAGAGAAAACAGTTTTTGGACAAGAGCTTCGAGTAGGAAGCAGGGAAGCTGCCTTCACGTA TGCCATTACTGCTGCCGGGGTTGCACATGCTGTCACGGCCGCCTGCAGCCAGGGCAACCTCAGCAATTGTGGCTGTGAC CGAGAGAAACAGGGCTACTACAACCAGGAGGAGGGCTGGAAGTGGGGAGGCTGCTCTGCGGATATCAGATACGGCATTG AGTTCTCCCGGAGGTTTGTTGATGCCCGAGAAATCAAAAAGAATGCACGAAGGCTGATGAACTTGCACAACAATGAGGC TGGAAGAAAGGTGCTTGAAGAGAGAATGAAACTGGAGTGCAAGTGTCACGGAGTTTCAGGTTCCTGTACAACCAAGACC TGCTGGACCACACTTCCTAAATTCAGAGAGATCGGATATATTTTGAAAGAGAAATACAATGCTGCAGTGCAGGTGGAGG TGGTACGAGCCAGTAGACTAAGGCAGCCAACTTTCCTGAAGATCAAGCAGATCAAGAGTTACCAGAAACCAATGGAAAC AGATTTAGTGTACATCGAAAAGTCACCAAACTACTGCGAGGAAGATGCTTCCACAGGAAGTGTTGGCACCCAGGGACGA CTCTGTAACCGCACCTCTCCCAATGCGGATGGGTGTGACATGATGTGCTGTGGAAGAGGTTACAACACACACCAGTACA CCAAGGTGTGGCAGTGCAACTGCAAATTCCACTGGTGCTGTTTTGTGAAGTGCAACACTTGTAGCGAGCGGACAGAGGT GTTCACCTGCAAATAACGGCGTCGTGCA
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_001037274).

Stage

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Location (click to highlight)

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19-24

stage 22

Forebrain

25-28

stage 28

Forebrain

choroid plexus

Entry 2

GEISHA Id	Wnt7b.Chapman.2008	Data Source	Direct Submission
Complete cDNA Template Probe	show GACTGGGATTTAAGCGACACGATCGATTCGACTTTTTGTGCAATTTTTATGGCTCAGTCCATTCCCTAGATCATGCACA GAAACTTTCGGAAGTGGATTTTCTACGTGTTTTTATGCTTTGGAGTCATCTATGTCAAATTAGGAGCTTTGTCATCTGT GGTGGCTTTAGGAGCTAATATCATCTGCAACAAAATCCCAGGCTTGGCCCCTCGGCAGCGAGCAATCTGCCAGAGCCGC CCTGATGCCATCATTGTGATTGGAGAAGGGGCACAAATGGGAATCAATGAGTGCCAGTACCAGTTTCGGTATGGGAGGT GGAACTGCTCTGCGCTGGGAGAGAAAACAGTTTTTGGACAAGAGCTTCGAGTAGGAAGCAGGGAAGCTGCCTTCACGTA TGCCATTACTGCTGCCGGGGTTGCACATGCTGTCACGGCCGCCTGCAGCCAGGGCAACCTCAGCAATTGTGGCTGTGAC CGAGAGAAACAGGGCTACTACAACCAGGAGGAGGGCTGGAAGTGGGGAGGCTGCTCTGCGGATATCAGATACGGCATTG AGTTCTCCCGGAGGTTTGTTGATGCCCGAGAAATCAAAAAGAATGCACGAAGGCTGATGAACTTGCACAACAATGAGGC TGGAAGAAAGGTGCTTGAAGAGAGAATGAAACTGGAGTGCAAGTGTCACGGAGTTTCAGGTTCCTGTACAACCAAGACC TGCTGGACCACACTTCCTAAATTCAGAGAGATCGGATATATTTTGAAAGAGAAATACAATGCTGCAGTGCAGGTGGAGG TGGTACGAGCCAGTAGACTAAGGCAGCCAACTTTCCTGAAGATCAAGCAGATCAAGAGTTACCAGAAACCAATGGAAAC AGATTTAGTGTACATCGAAAAGTCACCAAACTACTGCGAGGAAGATGCTTCCACAGGAAGTGTTGGCACCCAGGGACGA CTCTGTAACCGCACCTCTCCCAATGCGGATGGGTGTGACATGATGTGCTGTGGAAGAGGTTACAACACACACCAGTACA CCAAGGTGTGGCAGTGCAACTGCAAATTCCACTGGTGCTGTTTTGTGAAGTGCAACACTTGTAGCGAGCGGACAGAGGT GTTCACCTGCAAATAACGGCGTCGTGCA
Comments	Insufficient information provided to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_001037274.1). Images Provided by Susan Chapman.

Stage

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Location (click to highlight)

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7-10

stage 7

stage 8

stage 9

stage 10

Forebrain
Hindbrain
Midbrain
Neural Plate/Tube
Paraxial Mesoderm

Entry 3

GEISHA Id	Wnt7b.McBride.2003	Data Source	Publication
Complete cDNA Template Probe	show GACTGGGATTTAAGCGACACGATCGATTCGACTTTTTGTGCAATTTTTATGGCTCAGTCCATTCCCTAGATCATGCACA GAAACTTTCGGAAGTGGATTTTCTACGTGTTTTTATGCTTTGGAGTCATCTATGTCAAATTAGGAGCTTTGTCATCTGT GGTGGCTTTAGGAGCTAATATCATCTGCAACAAAATCCCAGGCTTGGCCCCTCGGCAGCGAGCAATCTGCCAGAGCCGC CCTGATGCCATCATTGTGATTGGAGAAGGGGCACAAATGGGAATCAATGAGTGCCAGTACCAGTTTCGGTATGGGAGGT GGAACTGCTCTGCGCTGGGAGAGAAAACAGTTTTTGGACAAGAGCTTCGAGTAGGAAGCAGGGAAGCTGCCTTCACGTA TGCCATTACTGCTGCCGGGGTTGCACATGCTGTCACGGCCGCCTGCAGCCAGGGCAACCTCAGCAATTGTGGCTGTGAC CGAGAGAAACAGGGCTACTACAACCAGGAGGAGGGCTGGAAGTGGGGAGGCTGCTCTGCGGATATCAGATACGGCATTG AGTTCTCCCGGAGGTTTGTTGATGCCCGAGAAATCAAAAAGAATGCACGAAGGCTGATGAACTTGCACAACAATGAGGC TGGAAGAAAGGTGCTTGAAGAGAGAATGAAACTGGAGTGCAAGTGTCACGGAGTTTCAGGTTCCTGTACAACCAAGACC TGCTGGACCACACTTCCTAAATTCAGAGAGATCGGATATATTTTGAAAGAGAAATACAATGCTGCAGTGCAGGTGGAGG TGGTACGAGCCAGTAGACTAAGGCAGCCAACTTTCCTGAAGATCAAGCAGATCAAGAGTTACCAGAAACCAATGGAAAC AGATTTAGTGTACATCGAAAAGTCACCAAACTACTGCGAGGAAGATGCTTCCACAGGAAGTGTTGGCACCCAGGGACGA CTCTGTAACCGCACCTCTCCCAATGCGGATGGGTGTGACATGATGTGCTGTGGAAGAGGTTACAACACACACCAGTACA CCAAGGTGTGGCAGTGCAACTGCAAATTCCACTGGTGCTGTTTTGTGAAGTGCAACACTTGTAGCGAGCGGACAGAGGT GTTCACCTGCAAATAACGGCGTCGTGCA
Citation	McBride HJ, Fatke B, Fraser SE. Wnt signaling components in the chicken intestinal tract. Dev Biol. 2003 Apr 1;256(1):18-33.
Copyright	With permission from Elsevier Copyright © 2003 Elsevier B.V. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_001037274.1).

Stage

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Location (click to highlight)

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25-28

stage 26

stage 28

Hindgut
Midgut

Entry 4

GEISHA Id	Wnt7A.Quinlan.2009	Data Source	Publication
Complete cDNA Template Probe	show `GAGTTTCAGGTTCCTGTACAACCAAGACCTGCTGGACCACACTTCCTAAATTCAGAGAGATCGGATATATTTTGAAAGA GAAATACAATGCTGCAGTGCAGGTGGAGGTGGTACGAGCCAGTAGACTAAGGCAGCCAACTTTCCTGAAGATCAAGCAG ATCAAGAGTTACCAGAAACCAATGGAAACAGATTTAGTGTACATCGAAAAGTCACCAAACTACTGCGAGGAAGATGCTT CCACAGGAAGTGTTGGCACCCAGGGACGACTCTGTAACCGCACCTCTCCCAATGCGGATGGGTGTGACATGATGTGCTG TGGAAGAGGTTACAACACACACCAGTACACCAAGGTGTGGCAGTGCAACTGCAA`
Citation	Quinlan R, Graf M, Mason I, Lumsden A, Kiecker C. Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev. 2009 Sep 4;4:35.
Copyright	Copyright © 2009 Quinlan et al; licensee BioMed Central Ltd. [This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.]
Comments	Authors indicate the probes is associated with Accession # AAB35504. This is a peptide sequence. The partner cDNA sequence is posted from NM_001171593.

Stage

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Location (click to highlight)

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13-18

stage 13

stage 16

Midbrain

stage 19

Midbrain

Entry 5

GEISHA Id	Wnt7B.Quinlan.2009	Data Source	Publication
Complete cDNA Template Probe	show `GAGTTTCAGGTTCCTGTACAACCAAGACCTGCTGGACCACACTTCCTAAATTCAGAGAGATCGGATATATTTTGAAAGA GAAATACAATGCTGCAGTGCAGGTGGAGGTGGTACGAGCCAGTAGACTAAGGCAGCCAACTTTCCTGAAGATCAAGCAG ATCAAGAGTTACCAGAAACCAATGGAAACAGATTTAGTGTACATCGAAAAGTCACCAAACTACTGCGAGGAAGATGCTT CCACAGGAAGTGTTGGCACCCAGGGACGACTCTGTAACCGCACCTCTCCCAATGCGGATGGGTGTGACATGATGTGCTG TGGAAGAGGTTACAACACACACCAGTACACCAAGGTGTGGCAGTGCAACTGCAAA`
Citation	Quinlan R, Graf M, Mason I, Lumsden A, Kiecker C. Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev. 2009 Sep 4;4:35.
Copyright	Copyright © 2009 Quinlan et al; licensee BioMed Central Ltd. [This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.]
Comments	Authors indicated that the probe was from another reference (NCBI acc. # AAB35504.1). The sequence shown is the coding sequence for that peptide extracted from NCBI Acc.#NM_001037274.1.

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 13

stage 15

Forebrain
Midbrain

19-20

stage 20

Forebrain
Midbrain

Entry 6

GEISHA Id	WNT7B.Sienknecht.2009	Data Source	Publication
Complete cDNA Template Probe	show GACTGGGATTTAAGCGACACGATCGATTCGACTTTTTGTGCAATTTTTATGGCTCAGTCCATTCCCTAGATCATGCACA GAAACTTTCGGAAGTGGATTTTCTACGTGTTTTTATGCTTTGGAGTCATCTATGTCAAATTAGGAGCTTTGTCATCTGT GGTGGCTTTAGGAGCTAATATCATCTGCAACAAAATCCCAGGCTTGGCCCCTCGGCAGCGAGCAATCTGCCAGAGCCGC CCTGATGCCATCATTGTGATTGGAGAAGGGGCACAAATGGGAATCAATGAGTGCCAGTACCAGTTTCGGTATGGGAGGT GGAACTGCTCTGCGCTGGGAGAGAAAACAGTTTTTGGACAAGAGCTTCGAGTAGGAAGCAGGGAAGCTGCCTTCACGTA TGCCATTACTGCTGCCGGGGTTGCACATGCTGTCACGGCCGCCTGCAGCCAGGGCAACCTCAGCAATTGTGGCTGTGAC CGAGAGAAACAGGGCTACTACAACCAGGAGGAGGGCTGGAAGTGGGGAGGCTGCTCTGCGGATATCAGATACGGCATTG AGTTCTCCCGGAGGTTTGTTGATGCCCGAGAAATCAAAAAGAATGCACGAAGGCTGATGAACTTGCACAACAATGAGGC TGGAAGAAAGGTGCTTGAAGAGAGAATGAAACTGGAGTGCAAGTGTCACGGAGTTTCAGGTTCCTGTACAACCAAGACC TGCTGGACCACACTTCCTAAATTCAGAGAGATCGGATATATTTTGAAAGAGAAATACAATGCTGCAGTGCAGGTGGAGG TGGTACGAGCCAGTAGACTAAGGCAGCCAACTTTCCTGAAGATCAAGCAGATCAAGAGTTACCAGAAACCAATGGAAAC AGATTTAGTGTACATCGAAAAGTCACCAAACTACTGCGAGGAAGATGCTTCCACAGGAAGTGTTGGCACCCAGGGACGA CTCTGTAACCGCACCTCTCCCAATGCGGATGGGTGTGACATGATGTGCTGTGGAAGAGGTTACAACACACACCAGTACA CCAAGGTGTGGCAGTGCAACTGCAAATTCCACTGGTGCTGTTTTGTGAAGTGCAACACTTGTAGCGAGCGGACAGAGGT GTTCACCTGCAAATAACGGCGTCGTGCA
Citation	Sienknecht UJ, Fekete DM. Mapping of Wnt, frizzled, and Wnt inhibitor gene expression domains in the avian otic primordium. J Comp Neurol. 2009 Dec 20;517(6):751-64.
Copyright	Copyright © (2002 Wiley-Liss); This material is used by permission of Wiley-Liss, Inc., a subsidiary of John Wiley & Sons, Inc.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_001037274.1 ).

Stage

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Location (click to highlight)

Comments (click to highlight)

stage 13

Ear/Otic Placode

HH stage 13+

Entry 7

GEISHA Id	Wnt7b.Garda.2002	Data Source	Publication
Complete cDNA Template Probe	show GACTGGGATTTAAGCGACACGATCGATTCGACTTTTTGTGCAATTTTTATGGCTCAGTCCATTCCCTAGATCATGCACA GAAACTTTCGGAAGTGGATTTTCTACGTGTTTTTATGCTTTGGAGTCATCTATGTCAAATTAGGAGCTTTGTCATCTGT GGTGGCTTTAGGAGCTAATATCATCTGCAACAAAATCCCAGGCTTGGCCCCTCGGCAGCGAGCAATCTGCCAGAGCCGC CCTGATGCCATCATTGTGATTGGAGAAGGGGCACAAATGGGAATCAATGAGTGCCAGTACCAGTTTCGGTATGGGAGGT GGAACTGCTCTGCGCTGGGAGAGAAAACAGTTTTTGGACAAGAGCTTCGAGTAGGAAGCAGGGAAGCTGCCTTCACGTA TGCCATTACTGCTGCCGGGGTTGCACATGCTGTCACGGCCGCCTGCAGCCAGGGCAACCTCAGCAATTGTGGCTGTGAC CGAGAGAAACAGGGCTACTACAACCAGGAGGAGGGCTGGAAGTGGGGAGGCTGCTCTGCGGATATCAGATACGGCATTG AGTTCTCCCGGAGGTTTGTTGATGCCCGAGAAATCAAAAAGAATGCACGAAGGCTGATGAACTTGCACAACAATGAGGC TGGAAGAAAGGTGCTTGAAGAGAGAATGAAACTGGAGTGCAAGTGTCACGGAGTTTCAGGTTCCTGTACAACCAAGACC TGCTGGACCACACTTCCTAAATTCAGAGAGATCGGATATATTTTGAAAGAGAAATACAATGCTGCAGTGCAGGTGGAGG TGGTACGAGCCAGTAGACTAAGGCAGCCAACTTTCCTGAAGATCAAGCAGATCAAGAGTTACCAGAAACCAATGGAAAC AGATTTAGTGTACATCGAAAAGTCACCAAACTACTGCGAGGAAGATGCTTCCACAGGAAGTGTTGGCACCCAGGGACGA CTCTGTAACCGCACCTCTCCCAATGCGGATGGGTGTGACATGATGTGCTGTGGAAGAGGTTACAACACACACCAGTACA CCAAGGTGTGGCAGTGCAACTGCAAATTCCACTGGTGCTGTTTTGTGAAGTGCAACACTTGTAGCGAGCGGACAGAGGT GTTCACCTGCAAATAACGGCGTCGTGCA
Citation	Garda AL, Puelles L, Rubenstein JL, Medina L. Expression patterns of Wnt8b and Wnt7b in the chicken embryonic brain suggest a correlation with forebrain patterning centers and morphogenesis. Neuroscience. 2002;113(3):689-98.
Copyright	Copyright © 2002 IBRO. Published by Elsevier Ltd.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_001037274.1).