GEISHA - A Chicken Embryo Gene Expression Database
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NF1
neurofibromin 1

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolNF1
Official Full Nameneurofibromin 1
CGNC ID49643
also known asneurofibromin
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Sequence Information
Genomic
RNAXM_003642416
PolypeptideXP_003642464
Gene Expression
In Situ HybridizationGEISHA
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly43149FBgn0015269
Human4763ENSG00000196712MIM:607785MIM:613113
Mouse18015ENSMUSG00000020716All phenotypic alleles (7):Targeted, knock-out(4) Targeted, other(3) MGI:97306
Xenopus100493879488023
Zebrafish564518, 326708ENSDARG00000004184, ENSDARG00000012982ZDB-GENE-091111-4, ZDB-GENE-030131-4907ZFIN:ZDB-GENE-091111-4, ZFIN:ZDB-GENE-030131-4907
Gene Ontology
Molecular FunctionRas GTPase activator activity
Biological Processnegative regulation of fibroblast proliferation
Cellular Component
Links to other databases
Entrez Gene396085
Ensembl GeneENSGALG00000005660
KEGGgga:396085
GEISHA IdNF1.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template Primer5’-CACTGGGTGCTACAGACGTT-3’
Reverse cDNA Template Primer5’-AATTAACCCTCACTAAAGGGCAAAACAAGAAGGGCTGGG-3’cDNA Template Length849
Complete cDNA Template Probeshow
CACTGGGTGCTACAGACGTTACCTGCACGGACTGAAGATGCGCAGAGCGTTGGACCTCAGAGGTGAATGGGCATTCTGA
CAAAGGCCTGCCATCCAGGTGCTCATTGTAGGGCTAAGCAAATCTACTGCTAGAAAACAGATAAACTTCCTAGATTGAG
ATCTGTTGTATGTTAGAAGTTAACAACAGTGAATGGCTTTAGAAGGGAAAAAAAGGTATATCCACTGTATGAAAAAAAT
AAAATCCTCTAGTGCAATGTTATCAGTGGCTTTCAGTAAATCAAACTCCACAGCTAAATTATTAGAGAATGGTACAATT
ATAAGTGTTCAGATTTTATTGATATAGCACATAATTCACGTGTATCCACACAGTAACAATGTAACATTTATGTAAATAA
AAATGCCTTTATTGTATTGATTCATAAAATAACAATTCTTCTAATTTGTTTACAGTCCTGGAAGAACTATGAACACAAG
CTTAATATGCAAATAGTTTGCCAAAACAAGAGGAAGATGTAGAATTAGCGGTCTTGAAATAGAATCATTGGAAAATACA
AAAAGTTGTGCAATTAACCATATTGTTTTATTCTTGATTGTGTAGGAGCTGCAGTAGAAACATGATTCCTGAACTGTGA
GATCTATGGAAGGGTTACAAGGCTAGACCTAAATTAAGGAATAGAGCAGTGACTTTTGCCATGTTTTTAAGCTGCTATG
CATTTGTAATTTTGGGAGTCACTGATTTAAAAACCTTTCTCATCTCATACATCAAATTGCTAATAGCCACCTTGGTATC
GCTGTCGGTTTGCACCTGATTATACTGAACCAAGCTGTTCCCAGCCCTTCTTGTTTTGC
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 7
stage 10
stage 11
Forebrain
Head Mesenchyme
Hindbrain
Midbrain
Neural Plate/Tube
Unlabeled
 
13-18
stage 16
stage 18
Ear/Otic Placode
Foregut
Head Mesenchyme
Heart
Leg Mesenchyme
Lung
Neural Plate/Tube
Notochord
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Tail
Widespread Expression
Wing Mesenchyme
 
19-24
stage 23
stage 23
Foregut
Head Mesenchyme
Leg Mesenchyme
Liver
Lung
Neural Plate/Tube
Pharyngeal Arches and Clefts
Sclerotome
Wing Mesenchyme
 
25
stage 25
stage 25
Foregut
Head Mesenchyme
Leg Mesenchyme
Liver
Lung
Pharyngeal Arches and Clefts
Sclerotome
Spinal Cord
Wing Mesenchyme
 

Mouse

EmageMGI:97306
MGI GXDMGI:97306

Frog

Xenbase488023

Fruit Fly

BDGPFBgn0015269

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-091111-4, ZDB-GENE-030131-4907
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