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Human Disease Gene Search
CDH5 Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol CDH5 Official Full Name cadherin 5 CGNC ID 3922 also known as cadherin-5, cadherin-5|cadherin 5, type 2 (vascular endothelium)|cadherin 5, type 2, VE-cadherin (vascular endothelium)|cadherin 5, type 2, VE-cadherin (vascular epithelium), VE-Cadherin
, cadherin 5, type 2, vascular endothelium cadherin gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Links to other databases
Entry 1 GEISHA Id CDH5.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer GCTATGATGTGTCCGTGCTCAAC Reverse cDNA Template Primer ATTAACCCTCACTAAAGGCCTTCTTTCCTCTGCTGGGTAAG cDNA Template Length 869 Forward cDNA Template Probe show CATAAGCGCGCAGNTATCAATAAAGATGGTTACTGTCAGGGCCAGGCAGGCTGGAGATGCAGGAGGTTATAAAAACATT
Entry 2 GEISHA Id Cadherin-5 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show GACTTTTCTGTTTGTTCTTCTTTTTCTATGTACTGCTTAATGTTATGGGACACCGCTGAACTTAGTTTGCCTCATTTGG
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 4-6 stage 6
7-11 stage 8
stage 10
stage 11
Blood Islands Blood Vessels
Entry 3 GEISHA Id VE-Cadherin.Bollerot.2005 Data Source Publication Complete cDNA Template Probe show CAATGGATCTGTCCCAGAAATGTCACGATTAGGAACCTCAGTTACCAAAGTGACAGCTGAAGATGCCGATGACCCAACA
Citation Bollerot K, Romero S, Dunon D, Jaffredo T. Core binding factor in the early avian embryo: cloning of Cbfbeta and combinatorial expression patterns with Runx1. Gene Expr Patterns. 2005 Dec;6(1):29-39. Epub 2005 Jul 19. Copyright Copyright © 2005 Elsevier B.V. All rights reserved. Comments According to the authors, "The VE-cadherin probe was obtained from the clone pgp1n.pk007.4 (Delaware Biotechnology Institute). After a PCR amplification using the following primers: 5'-CAATGGATCTGTCCCAGAAA-3′ (forward) and 5'-GTCAGTAGCTGAAATCCTGA-3' (reverse), the insert encompassing 1050 bp was subcloned into pCR-II. Sense and antisense RNA probes were synthetised using r-UTP-Digoxygenin (Roche)." The sequence below was obtained from NCBI (NM_204227) using the given primers.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 18
stage 18
stage 18
Cranial Ganglia Hindbrain
Entry 4 GEISHA Id VE-Cadherin.Jaffredo.2005 Data Source Publication Complete cDNA Template Probe show GACTTTTCTGTTTGTTCTTCTTTTTCTATGTACTGCTTAATGTTATGGGACACCGCTGAACTTAGTTTGCCTCATTTGG
Citation Jaffredo T, Bollerot K, Sugiyama D, Gautier R, Drevon C (2005). Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells.
Int J Dev Biol. 2005;49(2-3):269-77. Copyright "Reprinted from Int. J. Dev. Biol., 49,Jaffredo T, Bollerot K, Sugiyama D, Gautier R, Drevon C , Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells, 269-77, Copyright (2005), with permission from Copyright © 2005 UBC Press". All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_204227).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 18
Aorta 31-44 stage 44
Aorta Blood
Entry 5 GEISHA Id CDH5.Moran.2012 Data Source Publication Complete cDNA Template Probe show GACTTTTCTGTTTGTTCTTCTTTTTCTATGTACTGCTTAATGTTATGGGACACCGCTGAACTTAGTTTGCCTCATTTGG
Citation Moran CM, Myers CT, Lewis CM, Krieg PA. Hedgehog regulates angiogenesis of intersegmental vessels through the VEGF signaling pathway. Dev Dyn. 2012 Jun;241(6):1034-42. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI ( NM_204227.1).
Entry 6 GEISHA Id VECADHERIN.Li.2013 Data Source Publication Complete cDNA Template Probe show GACTTTTCTGTTTGTTCTTCTTTTTCTATGTACTGCTTAATGTTATGGGACACCGCTGAACTTAGTTTGCCTCATTTGG
Citation Li Y, Wang XY, Wu T, Chuai M, Lee KK, Wang LJ, Yang X. PTEN is involved in modulation of vasculogenesis in early chick embryos. Biol Open. 2013 June 15; 2(6): 587595. Published online 2013 May 9. Copyright Copyright held by the authors. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204227.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 1-3 stage 3
stage 3
stage 3
Blood Islands Neural Plate/Tube
Mouse Frog Fruit Fly Zebra Finch Zebrafish
