GEISHA - A Chicken Embryo Gene Expression Database
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CTSB
cathepsin B

Gene
Official SymbolCTSB
Official Full Namecathepsin B
CGNC ID12486
also known ascathepsin B|cathepsin B1, Cathepsin B precursor , Cathepsin B1, Cathepsin B light chain; Cathepsin B heavy chain
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Sequence Information
Genomic
RNANM_205371
PolypeptideNP_990702
Gene Expression
In Situ HybridizationGEISHA
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly32341FBgn0030521
Human1508ENSG00000164733MIM:116810
Mouse13030ENSMUSG00000021939All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2) MGI:88561
Xenopus394833, 3792571000504
Zebrafish406645, 569298ENSDARG00000055120ZDB-GENE-040426-2650, ZDB-GENE-070323-1ZFIN:ZDB-GENE-040426-2650, ZFIN:ZDB-GENE-070323-1
Gene Ontology
Molecular Functioncysteine-type endopeptidase activity
Biological Processproteolysis, regulation of catalytic activity
Cellular Componentlysosome
Links to other databases
Entrez Gene396329
Ensembl GeneENSGALG00000016666
KEGGgga:396329
GEISHA IdCathepsinB.Zuzarte-Luis.2007aData SourcePublication
Complete cDNA Template Probeshow
ACTGACATGAGCTATGTGAAGAAGCTCTGTGGCACTTTCCTGGGTGGACCCAAGGCTCCTGAAAGGGTAGATTTTGCTG
AGGATATGGATTTGCCGGATACCTTTGACACGCGGAAGCAATGGCCAAATTGCCCCACCATCAGCGAGATCAGAGACCA
GGGCTCCTGTGGCTCTTGCTGGGCTTTTGGTGCTGTGGAAGCGATTTCGGACAGAATCTGTGTTCACACCAACGCCAAG
GTGAGCGTGGAGGTGTCGGCGGAGGATTTGCTGTCATGCTGTGGCTTCGAGTGCGGCATGGGGTGCAATGGTGGTTATC
CTTCTGGTGCATGGAGGTACTGGACAGAGAGGGGCCTCGTGTCTGGGGGTCTCTATGACTCCCATGTGGGCTGCCGGGC
CTACACCATCCCACCCTGTGAGCACCACGTCAATGGCTCCCGGCCACCTTGCACTGGGGAGGGAGGAGAAACCCCCAGG
TGCAGCCGGCACTGTGAACCTGGCTACTCGCCTTCCTACAAGGAGGACAAGCACTACGGCATCACATCCTAC
CitationZuzarte-Luis V, Montero JA, Kawakami Y, Izpisua-Belmonte JC, Hurle JM. Lysosomal cathepsins in embryonic programmed cell death. Dev Biol. 2007 Jan 1;301(1):205-17. Epub 2006 Aug 12.
Copyright2006 Elsevier Inc. All rights reserved.
CommentsAuthors said: For in situ hybridization, antisense probes for cathepsin D, B, and L (Zuzarte-Luis et al.,[2007]), for cCatB—fwd: 5′-ACT GAC ATG AGC TAT GTG AAG-3′ and rev: 5′-GTA GGA TGT GAT GCC GTA GT-3. The probe shown was excerpted from Acc# NM_205371 using these primers.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 30
Leg
 
31-32
stage 32
stage 32
Leg
 

Mouse

EmageMGI:88561
MGI GXDMGI:88561

Frog

Xenbase1000504

Fruit Fly

BDGPFBgn0030521

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040426-2650, ZDB-GENE-070323-1
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