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DKK1 Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol DKK1 Official Full Name dickkopf WNT signaling pathway inhibitor 1 CGNC ID 2791 also known as DKK4, dickkopf-related protein 1|dickkopf WNT signaling pathway inhibitor 4|dickkopf homolog 1 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id Dkk1.Chapman.2004 Data Source Publication Complete cDNA Template Probe show CGACGAACGCCCGCGCCCGCCTGGCCGCCCGACGCCAAAGGTGAGGAGGGCGACTTCTGCCTGCGCTCGTCGGACTGCG
Citation Chapman, S, Brown, R, Lees, L, Schoenwolf, G, Lumsden, A. Expression Analysis of Chick Wnt and Frizzled Genes and Selected Inhibitors in Early Chick Patterning. Dev Dyn. 2004 Mar;229(3):668-76. Copyright Wiley-Liss, Inc. 2004 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # AY049017).
Entry 2 Entry 3 GEISHA Id Dkk-1.Manisastry.2006 Data Source Publication Complete cDNA Template Probe show ATGGCGCAACCGAGCCGTCGGGGGGCCCCGAGGGCGAGGGGCGGGGGGAGCCGCGCCCCTTTGATCTCCGCGCATCAAA
Citation Manisastry SM, Han M, Linask KK. Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development. Dev Dyn. 2006 Aug;235(8):2160-74. Copyright Copyright © 2006 Wiley-Liss, Inc. Comments Authors said: "The chick probe for Dkk-1 was provided by Dr. Susan C. Chapman (University of Utah, Salt Lake City, UT)." Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_421563).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 4-6 stage 4
stage 4
Lateral Plate Mesoderm 7-11 stage 11
Unlabeled
Entry 4 GEISHA Id Dkk1.Abe.2006 Data Source Publication Complete cDNA Template Probe show ATGGCGCAACCGAGCCGTCGGGGGGCCCCGAGGGCGAGGGGCGGGGGGAGCCGCGCCCCTTTGATCTCCGCGCATCAAA
Citation Abe Y, Chen W, Huang W, Nishino M, Li YP.
CNBP regulates forebrain formation at organogenesis stage in chick embryos. Dev Biol. 2006 Jul 1;295(1):116-27. Epub 2006 Apr 19. Copyright Reprinted from Developmental Biology, 295, Yoko Abea, Wei Chena, Wei Huangc, Mizuho Nishinod and Yi-Ping Li, CNBP regulates forebrain formation at organogenesis stage in chick embryos, 116-127, Copyright 2006, with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights reserved.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19 stage 19
Forebrain Midbrain Somites
Entry 5 GEISHA Id Dkk1.Chapman.2008 Data Source Direct Submission Complete cDNA Template Probe show CGACGAACGCCCGCGCCCGCCTGGCCGCCCGACGCCAAAGGTGAGGAGGGCGACTTCTGCCTGCGCTCGTCGGACTGCG
Comments Images Provided by Susan Chapman
Entry 6 GEISHA Id DKK1.Foley.2000 Data Source Publication Complete cDNA Template Probe show ATGGCGCAACCGAGCCGTCGGGGGGCCCCGAGGGCGAGGGGCGGGGGGAGCCGCGCCCCTTTGATCTCCGCGCATCAAA
Citation Foley AC, Skromne I, Stern CD. Reconciling different models of forebrain induction and patterning: a dual role for the hypoblast. Development. 2000 Sep;127(17):3839-54.
Copyright Printed in Great Britain © The Company of Biologists Limited 2000 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_421563).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) X-XIV stage XII
Hypoblast 1-3 stage 2
Hypoblast 4 stage 4
stage 4
Hypoblast
Entry 7 GEISHA Id DKK1.Geetha-Loganathan.2009 Data Source Publication Complete cDNA Template Probe show ATGGCGCAACCGAGCCGTCGGGGGGCCCCGAGGGCGAGGGGCGGGGGGAGCCGCGCCCCTTTGATCTCCGCGCATCAAA
Citation Geetha-Loganathan, P, Nimmagadda, S, Antoni, L, Fu, K, Whiting, C, Francis-West, P and Richman, J. Expression of WNT signalling pathway genes during chicken craniofacial development. DEVELOPMENTAL DYNAMICS
Volume 238, Issue 5, May 2009, Pages: 11501165. Copyright Dev. Dyn Copyright © 2009 John Wiley & Sons, Inc. All Rights Reserved. Comments Authors indicated the probe could be found in another publication (see text). As this information was insufficient to determine the precise probe, we've included NCBI acc# XM_421563 for this gene.
Entry 8 GEISHA Id DKK1.Sienknecht.2009 Data Source Publication Complete cDNA Template Probe show CCGCCGGCCGCCACCCGGCAGCCCTTCCCCTGCTCCGAGGACGAGGACTGCGGCCCCGACGAATTCTGCGGAGGGGCGG
Citation Sienknecht UJ, Fekete DM. Mapping of Wnt, frizzled, and Wnt inhibitor gene expression domains in the avian otic primordium. J Comp Neurol. 2009 Dec 20;517(6):751-64. Copyright Copyright © (2002 Wiley-Liss); This material is used by permission of Wiley-Liss, Inc., a subsidiary of John Wiley & Sons, Inc. Comments Authors gave NCBI acc# in the paper
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 16
stage 16
Ear/Otic Placode 19-23 stage 20
stage 20
stage 23
stage 23
Ear/Otic Placode
Entry 9 GEISHA Id DKK1.Anderson.2020 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show GAACAGCGGCACAGCCCCCCGGGGCCCTTTGAAATCCCATCCCTCCTCCCCGAAGGGCGGGCGCAGGAGGCAGCCCCCC
Comments Images provided by Claire Anderson. As insufficient information was provided to verify sequence used to synthesize probe, the sequence was obtained from NCBI (accession number XM_015278709.2).
Entry 10 GEISHA Id DKK1.Lee.2020 Data Source Publication Complete cDNA Template Probe show GAACAGCGGCACAGCCCCCCGGGGCCCTTTGAAATCCCATCCCTCCTCCCCGAAGGGCGGGCGCAGGAGGCAGCCCCCC
Citation Hyung Chul Lee, Hui-Chun Lu, Mark Turmaine, Nidia M. M. Oliveira, Youwen Yang† , Irene De Almeida and Claudio D. Stern. Molecular anatomy of the pre-primitive streak chick embryo Open Biol. null. 10.1098/rsob.190299. Copyright Copyright © 2020 The Authors. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_015278709.2). DKK1 also known as DKK4 in NCBI.
Mouse Frog Fruit Fly Zebra Finch Zebrafish
