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Gene Family QuickSearch
Human Disease Gene Search
GLI3 The human orthologue of this gene is associated
Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol GLI3 Official Full Name GLI family zinc finger 3 CGNC ID 9366 also known as GLI3FL, transcriptional activator GLI3|GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)|GLI3 full length protein, GLI3 , GKLF gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Links to other databases
Entry 1 GEISHA Id 42Q Data Source GEISHA ISH Analysis Forward cDNA Template Probe show GAAAACAATGGTTCCTATAGTTTGCAGCAGAACACGGTCCTTGGCAGCGGAGCCAGTAGTTCTTTCGGCATGCAGCCCA
Entry 2 GEISHA Id GLI3.Aglyamova.2007 Data Source Publication Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Citation Aglyamova GV, Agarwala S. Gene expression analysis of the hedgehog signaling cascade in the chick midbrain and spinal cord. Dev Dyn. 2007 May;236(5):1363-73 Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_418866).
Entry 3 GEISHA Id Gli3.vonFrowein.2006 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show TCTGTACCTTATCGTGGGACATTGTTTACTATGGACCCCAGAAATGGTTACATGGATCCTCATTACCATCCACCTCACC
Comments According to the authors, Plasmid templates were used to generate digoxygenin antisense riboprobes: Gli3 (C. Tabin) (Schweitzer et al., 2000). The sequence below came from Schweitzer (Acc# AF303886).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-22 stage 22
Forebrain
Entry 4 GEISHA Id GLI3.Granata.2004 Data Source Publication Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Citation Granata A, Quaderi NA. Asymmetric expression of Gli transcription factors in Hensen's node. Gene Expr Patterns. 2005 Apr;5(4):529-31. Epub 2004 Dec 15. Copyright Reprinted with permission from Elsevier. Copyright © 2004 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_418866).
Entry 5 GEISHA Id GLI3.Agarwala.2005 Data Source Publication Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Citation Agarwala S, Aglyamova GV, Marma AK, Fallon JF, Ragsdale CW. Differential susceptibility of midbrain and spinal cord patterning to floor plate defects in the talpid2 mutant. Dev Biol. 2005 Dec 1;288(1):206-20. Epub 2005 Oct 21. Copyright Copyright © 2005 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_418866).
Entry 6 GEISHA Id Gli3.Liu.2007 Data Source Publication Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Citation Liu G, Moro A, Zhang JJ, Cheng W, Qiu W, Kim PC. The role of Shh transcription activator Gli2 in chick cloacal development. Dev Biol. 2007 Mar 15;303(2):448-60. Epub 2006 Dec 15 Copyright Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # XM_418866.2)
Entry 7 GEISHA Id GLI3.Meyer.2003 Data Source Publication Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Citation Meyer NP, Roelink H. The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord. Dev Biol. 2003 May 15;257(2):343-55. Copyright Copyright © 2003 Elsevier Science (USA). All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_418866).
Entry 8 GEISHA Id GLI-3.Pacifici.2005 Data Source Publication Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Citation Pacifici M, Koyama E, Iwamoto M. Mechanisms of synovial joint and articular cartilage formation: recent advances, but many lingering mysteries. Birth Defects Res C Embryo Today. 2005 Sep;75(3):237-48. Copyright Copyright © 2005 Wiley-Liss, Inc. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #XM_418866).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-36 stage 36
stage 36
stage 36
stage 36
stage 36
Limb Buds
Entry 9 GEISHA Id GLI3.Luo.2006 Data Source Publication Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Citation Luo J, Ju MJ, Redies C. Regionalized cadherin-7 expression by radial glia is regulated by Shh and Pax7 during chicken spinal cord development. Neuroscience. 2006 Nov 3 Copyright © 2006 IBRO. Published by Elsevier Ltd. All rights reserved.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-20 stage 20
stage 20
Spinal Cord
Entry 10 GEISHA Id Gli3.Schweitzer.2000 Data Source Publication Complete cDNA Template Probe show TCTGTACCTTATCGTGGGACATTGTTTACTATGGACCCCAGAAATGGTTACATGGATCCTCATTACCATCCACCTCACC
Citation Schweitzer R, Vogan KJ, Tabin CJ. Similar expression and regulation of Gli2 and Gli3 in the chick limb bud. Mech Dev. 2000 Nov;98(1-2):171-4. Copyright Copyright © 2000 Elsevier Science Ireland Ltd. Comments The complete cDNA template sequence was obtained from the information in the publication as described in Schweitzer et al. 2000.
Entry 11 GEISHA Id GLI3.Singh.2016 Data Source Publication Complete cDNA Template Probe show TCTGTACCTTATCGTGGGACATTGTTTACTATGGACCCCAGAAATGGTTACATGGATCCTCATTACCATCCACCTCACC
Citation Singh PN, Ray A, Azad K, Bandyopadhyay A. A comprehensive mRNA expression analysis of developing chicken articular cartilage. Gene Expr Patterns. 2016 Jan;20(1):22-31. Copyright Copyright © 2015 Elsevier B.V. All rights reserved. Comments The complete cDNA template sequence was obtained from the information from the publication as described in Singh et al. 2016.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 28
Limb Buds 31-38 stage 31
stage 34
stage 36
stage 38
Limb Buds all
Entry 12 GEISHA Id GLI3.Kahane.2013 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show ATGGAGGCGCAGTCCCATAGCTCTACCACGACAGAGAAGAAAAAAGTGGAGAATTCCATTGTGAAATGCTCCAATCGAA
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_001271903.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-17 stage 17
Dermomyotome all
Entry 13 GEISHA Id GLI3.Anderson.2021 Data Source Direct Submission Complete cDNA Template Probe show TCTGTACCTTATCGTGGGACATTGTTTACTATGGACCCCAGAAATGGTTACATGGATCCTCATTACCATCCACCTCACC
Comments Images and probe sequence information provided by Claire Anderson. Probe sequence is associated with GenBank: AF303886, according to the following article: Mech Dev 2000 Nov;98(1-2):171-4. doi: 10.1016/s0925-4773(00)00458-5. Similar expression and regulation of Gli2 and Gli3 in the chick limb bud. R Schweitzer 1, K J Vogan, C J Tabin.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Widespread Expression
Entry 14 GEISHA Id GLI3.Trevers.2023 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show GAGCCAGAGGGCAGCGCTCGGGAGAGAGGTCGGCGGCGGCGGGCGCTCTGCAACATCTGCACAACTCGGAGAGCGGCGG
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI ( NM_001271903).
Mouse Frog Fruit Fly Zebra Finch Zebrafish
