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PCNA
proliferating cell nuclear antigen

Gene

Official Symbol	PCNA
Official Full Name	proliferating cell nuclear antigen
CGNC ID	92
also known as	proliferating cell nuclear antigen
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4036

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	37290			FBgn0005655
Human	5111	ENSG00000132646		MIM:176740
Mouse	18538	ENSMUSG00000027342	All phenotypic alleles (5):Targeted, knock-out(1) Targeted, other(4)	MGI:97503
Xenopus	493302, 394328			972521
Zebrafish	30678	ENSDARG00000054155	ZDB-GENE-000210-8	ZFIN:ZDB-GENE-000210-8

Gene Ontology

Molecular Function	DNA polymerase processivity factor activity, MutLalpha complex binding, more...
Biological Process	DNA repair, DNA replication, mismatch repair, positive regulation of deoxyribonuclease activity, more...
Cellular Component	PCNA complex, PCNA-p21 complex, cytoplasm, microtubule cytoskeleton, nuclear replication fork, nucleoplasm

Links to other databases

GEISHA Id	PCNA.Tao.2002	Data Source	Publication
Complete cDNA Template Probe	show GATGTTTGAGGCGCGGCTTGTGCAGGGCTCGGTGCTCAAGCGGGTGCTGGAGGCCCTGAAGGACCTCATCACTGAGGCG TGCTGGGACCTGGGTTCGGGCGGCATCAGCCTGCAGAGCATGGACTCCTCGCACGTCTCCCTGGTGCAGCTCACGCTGC GCTCTGAGGGCTTCGACACCTACCGCTGCGACCGCAACATCGCCATGGGCGTCAACCTAAACAGCATGTCTAAAATACT GAAGTGTGCTGGAAATGAAGACATCATAACACTCAGAGCAGAAGACAATGCGGATACGTTGGCTCTAGTGTTTGAAGCA CCAAATCAGGAAAAGGTTTCTGATTATGAGATGAAGCTTATGGACCTCGATGTGGAGCAGCTTGGAATTCCAGAACAAG AATACAGTTGTGTAGTGAAAATGCCTTCTGCTGAATTTGCACGCATTTGTAGAGACCTCAGCCACATTGGTGATGCTGT TGTCATCTCCTGTGCAAAAGACGGTGTGAAATTTTCAGCTAATGGAGAGTTAGGAAATGGAAACATCAAGCTGTCACAG ACCAGTAATGTGGACAAAGAGGAAGAAGCTGTTACAATAGAAATGAATGAGCCAGTCCAGCTGACTTTTGCTCTGAGGT ATTTGAACTTTTTTACCAAAGCCACCCCCCTGTCACCTACAGTAACACTCAGCATGTCTGCAGATGTTCCTCTCGTTGT GGAGTACAAGATTGCTGATATGGGACACTTAAAATACTACCTGGCTCCAAAGATTGAAGACCAGCAGGAAGGCTCTTAA CTGCACTGGGACTGAGG
Citation	Tao H, Yoshimoto Y, Yoshioka H, Nohno T, Noji S, Ohuchi H. FGF10 is a mesenchymally derived stimulator for epidermal development in the chick embryonic skin. Mech Dev. 2002 Aug;116(1-2):39-49.
Copyright	Copyright © 2012 Elsevier B.V. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204170.2

Stage

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stage 1

GEISHA Id	PCNA.Zhang.2006	Data Source	Publication
Complete cDNA Template Probe	show GATGTTTGAGGCGCGGCTTGTGCAGGGCTCGGTGCTCAAGCGGGTGCTGGAGGCCCTGAAGGACCTCATCACTGAGGCG TGCTGGGACCTGGGTTCGGGCGGCATCAGCCTGCAGAGCATGGACTCCTCGCACGTCTCCCTGGTGCAGCTCACGCTGC GCTCTGAGGGCTTCGACACCTACCGCTGCGACCGCAACATCGCCATGGGCGTCAACCTAAACAGCATGTCTAAAATACT GAAGTGTGCTGGAAATGAAGACATCATAACACTCAGAGCAGAAGACAATGCGGATACGTTGGCTCTAGTGTTTGAAGCA CCAAATCAGGAAAAGGTTTCTGATTATGAGATGAAGCTTATGGACCTCGATGTGGAGCAGCTTGGAATTCCAGAACAAG AATACAGTTGTGTAGTGAAAATGCCTTCTGCTGAATTTGCACGCATTTGTAGAGACCTCAGCCACATTGGTGATGCTGT TGTCATCTCCTGTGCAAAAGACGGTGTGAAATTTTCAGCTAATGGAGAGTTAGGAAATGGAAACATCAAGCTGTCACAG ACCAGTAATGTGGACAAAGAGGAAGAAGCTGTTACAATAGAAATGAATGAGCCAGTCCAGCTGACTTTTGCTCTGAGGT ATTTGAACTTTTTTACCAAAGCCACCCCCCTGTCACCTACAGTAACACTCAGCATGTCTGCAGATGTTCCTCTCGTTGT GGAGTACAAGATTGCTGATATGGGACACTTAAAATACTACCTGGCTCCAAAGATTGAAGACCAGCAGGAAGGCTCTTAA CTGCACTGGGACTGAGG
Citation	Zhang X, Dai F, Weise C, Yusuf F, Bonafede A, Morosan-Puopolo G, Rehimi R, Wang J, Brand-Saberi B. Expression of the avian gene cNOC2 encoding nucleolar complex associated protein 2 during embryonic development. 2006 Nov;211(6):649-57
Copyright	© Springer-Verlag 2006
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_204170.2).