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PROX1 Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol PROX1 Official Full Name prospero homeobox 1 CGNC ID 7438 also known as prospero homeobox protein 1|PROX-1|homeobox prospero-like protein PROX1|prospero-related homeobox 1 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function DNA binding Biological Process cardiac muscle cell development , dorsal spinal cord development , heart development , more... hepatocyte differentiation , kidney development , lens development in camera-type eye , lens fiber cell morphogenesis , liver development , lymph vessel development , lymphangiogenesis , neural tube development , olfactory placode formation , otic placode formation , pancreas development , regulation of transcription, DNA-templated , retina morphogenesis in camera-type eye , transcription, DNA-templated Cellular Component cytoplasm , nucleus
Links to other databases
Entry 1 GEISHA Id ChEST49e24 Data Source GEISHA ISH Analysis Forward cDNA Template Probe show CTTTGCACGGAGGTCCCAGGATTCTTGAGCTGAGCCCAGCTGACAAGCTTTTGAAGATGGCACAATAACAGTCCAGTGA
Entry 2 GEISHA Id Prox1.Yanai.2005 Data Source Publication Complete cDNA Template Probe show GGTCCCAGGATTCTTGAGCTGAGCCCAGCTGACAAGCTTTTGAAGATGGCACAATAACAGTCCAGTGATGCCTGACCAT
Citation Yanai M, Tatsumi N, Endo F, Yokouchi Y. Analysis of gene expression patterns in the developing chick liver. Dev Dyn. 2005 Jul;233(3):1116-22. Copyright Wiley-Liss, Inc. 2005
Entry 3 GEISHA Id Prox1.Wilting.2006 Data Source Publication Complete cDNA Template Probe show CACAACTTCCACACGGCCAACCAGCGCCTGCAGTGCTTTGGGGACGTCATCATTCCAAACCCCCTCGACACCTTCAGCA
Citation Wilting J, Aref Y, Huang R, Tomarev SI, Schweigerer L, Christ B, Valasek P, Papoutsi M. Dual origin of avian lymphatics. Dev Biol. 2006 Apr 1;292(1):165-73. Epub 2006 Feb 2. Copyright "Reprinted from Developmental Biology, 292, Jörg Wilting, Yama Aref, Ruijin Huang, Stanislav I. Tomarev, Lothar Schweigerer, Bodo Christ, Petr Valasek and Maria Papoutsi, Dual Origin of Avian Lymphatics, 165-173, Copyright (2006), with permission from Elsevier".
Copyright © (2006) Elsevier B.V. All rights reserved. Comments For the detection of cProx1 mRNA, a chick probe was used that has been described by Tomarev et al., 1996. The 1880-bp probe was cloned into pBluescript SK- and corresponded to positions 14423322 of the coding region of the Prox1 gene. Linearization was performed with EcoRI (T3) and SacI (T7) for the preparation of sense and anti-sense probes, respectively.
Entry 4 GEISHA Id PROX1.Kurose.2004 Data Source Publication Complete cDNA Template Probe show TGATGCCTGACCATGACAGCACAGCCCTCTTAAGCAGGCAAACCAAGAGAAGAAGAGTTGACATTGGAGTGAAAAGGAC
Citation Kurose H, Bito T, Adachi T, Shimizu M, Noji S, Ohuchi H. Expression of Fibroblast growth factor 19 (Fgf19) during chicken embryogenesis and eye development, compared with Fgf15 expression in the mouse. Gene Expr Patterns. 2004 Oct;4(6):687-93. Copyright Reprinted with permission from Elsevier. Copyright © 2004 Elsevier B.V. All rights reserved. Comments The PCR primers, predicted size of the amplified product, and the GenBank Accession number for Prox1 (U46563) was given in the publication and used to obtain the sequence below.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-35 stage 35
stage 35
Retina
Entry 5 GEISHA Id PROX1.BeleckyAdams.1997 Data Source Publication Complete cDNA Template Probe show GGTCCCAGGATTCTTGAGCTGAGCCCAGCTGACAAGCTTTTGAAGATGGCACAATAACAGTCCAGTGATGCCTGACCAT
Citation Belecky-Adams T, Tomarev S, Li HS, Ploder L, McInnes RR, Sundin O, Adler R. Pax-6, Prox 1, and Chx10 homeobox gene expression correlates with phenotypic fate of retinal precursor cells. Invest Ophthalmol Vis Sci. 1997 Jun;38(7):1293-303. Copyright Copyright Association for Research in Vision and Ophthalmology
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 26
stage 26
Retina 31-44 stage 41
stage 41
stage 44
stage 44
Retina
Entry 6 GEISHA Id PROX1.Reza.2002 Data Source Publication Complete cDNA Template Probe show GGTCCCAGGATTCTTGAGCTGAGCCCAGCTGACAAGCTTTTGAAGATGGCACAATAACAGTCCAGTGATGCCTGACCAT
Citation Reza HM, Ogino H, Yasuda K. L-Maf, a downstream target of Pax6, is essential for chick lens development. Mech Dev. 2002 Aug;116(1-2):61-73. Copyright Copyright © 2002 Elsevier Science Ireland Ltd. All rights reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_001005616.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-17 stage 17
stage 17
Eye
Entry 7 GEISHA Id PROX.Larsen.2001 Data Source Publication Complete cDNA Template Probe show GGTCCCAGGATTCTTGAGCTGAGCCCAGCTGACAAGCTTTTGAAGATGGCACAATAACAGTCCAGTGATGCCTGACCAT
Citation Larsen CW, Zeltser LM, Lumsden A. Boundary formation and compartition in the avian diencephalon. J Neurosci. 2001 Jul 1;21(13):4699-711. Copyright Copyright © 2012 by the Society for Neuroscience
Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_001005616.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-26 stage 26
stage 26
Diencephalon
Entry 8 Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 18
Retina 19-24 stage 20
stage 22
stage 24
Retina 25-30 stage 26
stage 29
Retina 31-44 stage 32
stage 35
stage 35
stage 38
stage 41
stage 44
Retina all
Entry 9 Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-36 stage 31
stage 33
stage 34
stage 34
stage 36
Eye Unlabeled all
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