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THBS2
thrombospondin 2
The human orthologue of this gene is associated
with the following human disease:
{Lumbar disc herniation, susceptibility to}
Gene Summary
Expression
Other Species Expression
JBrowse
Gene
Official Symbol
THBS2
Official Full Name
thrombospondin 2
CGNC ID
49928
also known as
thrombospondin-2, thrombospondin-2
gene type
protein-coding
Genomic Map
Ensembl ID not known
NCBI
UCSC
Sequence Information
Genomic
RNA
NM_001001755
Polypeptide
NP_001001755
Gene Expression
In Situ Hybridization
GEISHA
Orthology
Entrez Gene
Ensembl Gene
Genetic Phenotypes
MOD
Fruit Fly
Human
7058
ENSG00000186340
MIM:603932
MIM:188061
Mouse
21826
ENSMUSG00000023885
All phenotypic alleles (
2
):Targeted, knock-out(
1
) Targeted, other(
1
)
MGI:98738
Xenopus
100494997
,
779026
482461
Zebrafish
566325
,
794881
ENSDARG00000073810
,
ENSDARG00000092466
ZDB-GENE-100623-1
,
ZDB-GENE-020708-2
ZFIN:ZDB-GENE-100623-1
,
ZFIN:ZDB-GENE-020708-2
Gene Ontology
Molecular Function
calcium ion binding
,
heparin binding
Biological Process
cell adhesion
,
negative regulation of angiogenesis
Cellular Component
basement membrane
Links to other databases
Entrez Gene
414837
Ensembl Gene
KEGG
gga:414837
GEISHA Id
TSP2.Bandyopadhyay.2008
Data Source
Publication
Complete cDNA Template Probe
show
ATGCTGCAGAGGAGCAGGCTGTTGTGGCTTGCTGTCTTCATAACCCTGTGGGTTTCCTCAGATGCTCAGGATGATGCCA
AAGAAGAGGAGAATACCTTTGATTTACTTCAAATCAGTAACATAAACCGAAAGACAATTGGAGCAAAATTGTTTCGGGG
TCCAGATCCCGCTATCCCAGCATATCGTTTCATTCGGTTTGACCATATACCTCCATTTAAACCAGAGAAGTTAAAAAAG
ATTGTTAAACTCATACGGCAAAATGAGGGCTTTATCCTTTCAGCCACCCTGAGACAGGACAGGCAATCTAGAGGCACTA
TCCTTGCTTTAGAGGGTCCTGGCATCAGTGAGAGGCAGTTTGAGATAATTTCCAATGGCCGAGCCAACACCCTGGACCT
CATTTATTGGGTGGATGGCTTCCAGAACGTGATTTCCCTGGAAGACGTGGACCTTGCTGACTCGCAGTGGAAGAACCTC
ACCGTGCAAGTAACAGGAGAGAACTACAACCTCTATGTTGGCTGTGACCTTATTGACAGCTTCATCCTGGAGGAGCCTT
TCTATGAGCAACTGAAAGCAGAGAACAGCAGAATGTATGTGGCGAAAGGGTCCATTCGGGAGAATCATTTCAGGGGTCT
TTTGCAAAATATTCATTTAATCTTTGATACTTCAATAGAGGATGTTCTACGTAAAAAAGGATGCCAGAGGAGCCAATCA
ACTGAAGTGAACACCATCAATGAGAGCACTGAGATTCTTCACTTGAGCCCTGCTGTCACGACTGAGTATGTAGGTGAAA
AGACAGAGAAGAAGGCTGAGTTCTGTGACCGCTCTTGTGAAGAGCTGGGAACAATGTTCACTGAACTCACTGGCCTGCG
CATTGTGGTGAACAATTTAGCTGATAACCTCCAAAAAGTGTCTGAAGAGAACCAAATAATGTGGGAATTGATTGGCCCT
AACAAAACACTCAAGAACCAATCAGTTTGCTGGCAGGATGGCCGAGTCTTTGCAGATAGTGAAAGCTGGATTGTAGATA
GCTGCACAAAGTGCACCTGCCAGGACTCTAAAATTGTGTGCCATCAAATCACCTGTCCACCAGTTTCTTGTGCTGATCC
GTCCTTTATTGAAGGTGAATGCTGTCCAGTCTGCTCTCACTCTGATGATAGTGAGGAAGGCTGGTCACCCTGGTCAGAC
TGGACAAAGTGCTCAGTTACCTGTGGCTCTGGGACTCAGATGAGAGGAAGGTCTTGTGATGTCACCAGGAGTGCTTGTA
CAGGCCCACACATTCAGACGAGGATGTGCAGCTTCAAGAAATGTGACCATCGCATACGTCAAGATGGTGGTTGGAGTCA
CTGGTCTCCCTGGTCCTCATGTTCAGTTACCTGTGGAGTAGGAAATATCACCCGCATCCGCCTCTGCAATTCCCCTATT
CCCCAGATGGGTGGGAAAAACTGTGTGGGAAATGGACGTGAAACAGAGAAATGTGAGAAGGCCCCGTGCCCAGTGAATG
GCCAGTGGGGTCCTTGGTCTCCATGGTCTGCTTGCACTGTTACCTGTGGAGGAGGAATCCGTGAGAGGTCTCGCCTCTG
TAACAGTCCAGAGCCACAGTATGGAGGAAAGCCATGTGTGGGAGATACCAAGCAACATGATATGTGCAATAAAAGGGAT
TGCCCAATTGATGGTTGTTTGTCAAATCCTTGCTTTCCTGGAGCAGAATGCAACAGTTACCCGGATGGATCGTGGTCAT
GTGGGCCATGCCCAGCAGGTTTCCTTGGCAATGGTACAGTCTGTGAGGATCTTGATGAGTGTATAGCTGTGTCAGATGT
TTGCTTTAAGGTGAATCAGGTCCATCGCTGTGTGAACACAAATCCGGGTTTCCATTGCTTGCCATGTCCTCCGCGTTAT
AAAGGAAGTCAGCCTTACGGAGTAGGGCTGGAAGTTGCCAAGACAGAGAAGCAAGTCTGTGAACCTGAGAATCCATGCA
AAGACAAGACACACAGCTGCCATAAATCTGCAGAGTGCATTTATCTGGGTCATTTCAGTGATCCTATGTACAAATGTGA
ATGTAGGACAGGTTATGCTGGTGATGGACGCATCTGTGGTGAGGATTCAGATTTGGATGGATGGCCAAATAATAACTTG
GTTTGTGCTGCTAATGCTACGTATCACTGTGTGAAGGATAACTGCCCCCTCCTGCCTAACTCTGGCCAAGAAGACTTTG
ATAAAGATGGCAAAGGAGATGCCTGTGATGAGGATGATGACAATGATGGTGTTGAAGATGACAAAGACAATTGCCCTCT
TCTGTTCAATCCTCGTCAGTTTGATTATGACAAAGATGAAGTTGGTGACCGCTGTGATAATTGCCCTTATGTGCACAAC
CCCGCACAGATTGACACAGATAATAATGGGGAGGGTGATTCATGTGCTGTGGATATTGATGGAGATGACATTTTTAATG
AACGAGATAATTGTCCTTACGTTTATAATACAGATCAGAGTGATACAGATGGTGATGGAGTTGGTGATCAGTGTGATAA
CTGTCCGCTAATGCATAATCCAGACCAGACTGATGCAGATAACGATCTTGTTGGTGACCAGTGTGACAACAATGAGGAC
ATAGATGAAGATGGCCACCAGAACAACCAAGATAACTGCCCTTACATCCCCAATGCTAACCAGGCTGACCATGATAAAG
ATGGTAAAGGGGATGCCTGTGATCCTGATGATGACAATGATGGTATTCCAGATGACAGGGACAATTGTCGCCTCAGATA
CAACCCTGAGCAGGAGGACTCTGATGGTGATGGCAGAGGTGATATTTGCAAAGATGACTTTGACGATGACAATGTTCCA
GATATTTTTGATGTATGTCCTGAAAACAATGCCATCAGTGAAACTGATTTCAGAAAGTTCCAGATGGTCCCTCTGGACC
CCAAGGGAACAGCTCAGATTGATCCCAACTGGGTTATTCGCCACCAAGGCAAGGAACTGGTGCAGACTGCCAACTCTGA
TCCTGGAATAGCTGTAGGTTATGATGAGTTCAGCTCTGTTGACTTCAGTGGCACATTCTATGTTAACACAGACCGTGAT
GATGACTATGCTGGCTTTGTTTTTGGCTACCAGTCCAGCAGCCGTTTTTATGTTCTGATGTGGAAGCAGGTCACTCAGA
CCTACTGGGAGGACAAACCCACCAGGGCTTATGGCTATTCTGGTGTGTCACTCAAGGTAGTGAATTCAACAACTGGTAC
TGGGGAACACTTGCGAAATGCTCTTTGGCATACAGGAAACACCCCTGGACAGGTGCGCACTTTATGGCATGATCCTAAG
AACATTGGCTGGAAAGATTATACTGCATACAGGTGGCATTTGATTCACAGGCCTAAAACAGGACTAATAAAAGTTCTAG
TGTATGAAGGGAAGCAAGTCATGGTGGATTCTGGACCAATCTATGATACAACCTTTGCTGGTGGACGATTAGGTCTATT
TGTCTTCTCTCAAGAAATGGTCTATTTCTCTGACCTCAAATATGAATGCAGAGATGCTTGA
Citation
Bandyopadhyay A, Kubilus JK, Crochiere ML, Linsenmayer TF, Tabin CJ. Identification of unique molecular subdomains in the perichondrium and periosteum and their role in regulating gene expression in the underlying chondrocytes. Dev Biol. 2008 Sep 1;321(1):162-74. doi: 10.1016/j.ydbio.2008.06.012. Epub 2008 Jun 16.
Copyright
Copyright © 2013 Elsevier B.V. All rights reserved.
Comments
As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_001001755.1
Stage
Image (click image to view full size)
Location (click to highlight)
Comments (click to highlight)
31-38
stage 36
stage 36
stage 38
stage 38
stage 38
Leg Bones
Mouse
Emage
MGI GXD
MGI:98738
Frog
Xenbase
482461
Fruit Fly
BDGP
Zebra Finch
ZEBrA
Zebrafish
ZFIN
ZDB-GENE-100623-1
,
ZDB-GENE-020708-2
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