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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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FGF9
fibroblast growth factor 9

The human orthologue of this gene is associated
with the following human disease:

Multiple synostoses syndrome 3

Gene

Official Symbol	FGF9
Official Full Name	fibroblast growth factor 9
CGNC ID	49145
also known as	fibroblast growth factor 9\|fibroblast growth factor 9 (glia-activating factor)\|glia-activating factor
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204399
Polypeptide	NP_989730

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	2254	ENSG00000102678	MIM:612961	MIM:600921
Mouse	14180		All phenotypic alleles (7):Spontaneous(1) Targeted, knock-out(2) Targeted, other(4)	MGI:104723
Xenopus	100217327, 378562			484465
Zebrafish			ZDB-GENE-070424-238	ZFIN:ZDB-GENE-070424-238

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	378917
Ensembl Gene
KEGG	gga:378917

Entry 1

GEISHA Id	FGF9.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TTATAAAAGCTTGCGGCCGCAGAATATGGTCAGCATCCGAGGAGTAGACAG
Reverse cDNA Template Primer	GCTCTAGAAATTAACCCTCACTAAAGGGCTAATCAATAAGAACCCACCGC	cDNA Template Length	394
Complete cDNA Template Probe	show `GGGCCTGGTCAGCATCCGAGGAGTAGACAGCGGACTCTACCTTGGAATGAATGAGAAAGGGGAGCTCTACGGCTCGGAA AAATTAACCCAGGAGTGTGTATTCAGAGAGCAGTTTGAAGAAAACTGGTATAACACATATTCATCAAATCTATATAAAC ACGTGGACACTGGAAGACGATACTACGTGGCGTTAAATAAAGATGGAACTCCAAGAGAAGGGACTAGGACTAAACGGCA TCAAAAATTTACACATTTTTTACCTAGACCAGTGGACCCTGAGAAAGTACCTGAACTATATAAGGATATTTTAAGCCAA AGTTGACAAAGACAATTCCTTCACTTGAGCCCTTAAAAAGTAACCACTATAAAGGTTTCATGCGGTGGGTTCTTATTGA TTAGCTGTGT`
Comments	No specific expression detected prior to stage 12.

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Unlabeled

7-12

stage 7

stage 9

stage 12

Anterior Neuropore
Oral Pharynx
Unlabeled

Staining observed in neural tube may be due to trapping.

13-18

stage 13

stage 17

Forebrain
Leg AER
Oral Pharynx
Wing AER

19-24

stage 20

stage 21

Leg AER
Wing AER

stage 25

Eye
Leg AER
Lung
Nasal Placode/Nerve
Pharyngeal Arches and Clefts
Somites
Spinal Ganglia and Nerves
Wing AER

Entry 2

GEISHA Id	FGF9.Yoshioka.2005	Data Source	Publication
Complete cDNA Template Probe	show ATGGCTCCTCTCGGGGAGGTTGGGAACTATTTCGGTGTGCAGGACGCGGTGCCCTTTGGGAACGTGCCCGCGCTGCCGG CGGACAGCCCGGTTTTGCTCAGTGACCACCTGGGCCAGGCTGAGGCAGGTGGGCTGCCCAGGGGCCCCGCGGTCACGGA CTTGGACCATTTAAAGGGGATCCTCAGGAGGAGGCAGCTCTACTGCAGGACTGGATTTCATTTAGAAATCTTCCCCAAT GGTACTATCCAGGGCACCAGGCAAGACCACAGCCGATTCGGTATACTGGAGTTCATCAGTATAGCAGTGGGCCTGGTCA GCATCCGAGGAGTAGACAGCGGACTCTACCTTGGAATGAATGAGAAAGGGGAGCTCTACGGCTCGGAAAAATTAACCCA GGAGTGTGTATTCAGAGAGCAGTTTGAAGAAAACTGGTATAACACATATTCATCAAATCTATATAAACACGTGGACACT GGAAGACGATACTACGTGGCGTTAAATAAAGATGGAACTCCAAGAGAAGGGACTAGGACTAAACGGCATCAAAAATTTA CACATTTTTTACCTAGACCAGTGGACCCTGAGAAAGTACCTGAACTATATAAGGATATTTTAAGCCAAAGTTGACAAAG ACAATTCCTTCACTTGAGCCCTTAAAAAGTAACCACTATAAAGGTTTCATGCGGTGGGTTCTTATTGATTAGCTGTGTC ATCACATCAGCTCCACTGTTGCCAAACTTTGTCGCATGCATAATGTATGATGGAGGCTTGGATGGAACATGCTGATTTT GTTCTGCACTTAAAGGTTTGTCCTCCTGG
Citation	Yoshioka H, Ishimaru Y, Sugiyama N, Tsunekawa N, Noce T, Kasahara M, Morohashi K (2005). Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos. Dev Biol. 2005 Apr 1;280(1):150-61.
Copyright	Copyright © 2005 Elsevier Inc. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AB108842). Accession given in paper.

Stage

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Location (click to highlight)

Comments (click to highlight)

19-24

stage 21

Gonad
Trunk Mesenchyme

Comma-shaped Body
Gonadal Primordium
Mesonephric Mesenchyme
Nephrogenous Mesenchyme

25-30

stage 30

Gonad

Female chick embryos
Male chick embryo
Mesonephros

Entry 3

GEISHA Id	FGF9.Havens.2006	Data Source	Publication
Complete cDNA Template Probe	show ATGGCTCCTCTCGGGGAGGTTGGGAACTATTTCGGTGTGCAGGACGCGGTGCCCTTTGGGAACGTGCCCGCGCTGCCGG CGGACAGCCCGGTTTTGCTCAGTGACCACCTGGGCCAGGCTGAGGCAGGTGGGCTGCCCAGGGGCCCCGCGGTCACGGA CTTGGACCATTTAAAGGGGATCCTCAGGAGGAGGCAGCTCTACTGCAGGACTGGATTTCATTTAGAAATCTTCCCCAAT GGTACTATCCAGGGCACCAGGCAAGACCACAGCCGATTCGGTATACTGGAGTTCATCAGTATAGCAGTGGGCCTGGTCA GCATCCGAGGAGTAGACAGCGGACTCTACCTTGGAATGAATGAGAAAGGGGAGCTCTACGGCTCGGAAAAATTAACCCA GGAGTGTGTATTCAGAGAGCAGTTTGAAGAAAACTGGTATAACACATATTCATCAAATCTATATAAACACGTGGACACT GGAAGACGATACTACGTGGCGTTAAATAAAGATGGAACTCCAAGAGAAGGGACTAGGACTAAACGGCATCAAAAATTTA CACATTTTTTACCTAGACCAGTGGACCCTGAGAAAGTACCTGAACTATATAAGGATATTTTAAGCCAAAGTTGACAAAG ACAATTCCTTCACTTGAGCCCTTAAAAAGTAACCACTATAAAGGTTTCATGCGGTGGGTTCTTATTGATTAGCTGTGTC ATCACATCAGCTCCACTGTTGCCAAACTTTGTCGCATGCATAATGTATGATGGAGGCTTGGATGGAACATGCTGATTTT GTTCTGCACTTAAAGGTTTGTCCTCCTGG
Citation	Havens BA, Rodgers B, Mina M. Tissue-specific expression of Fgfr2b and Fgfr2c isoforms, Fgf10 and Fgf9 in the developing chick mandible. Arch Oral Biol. 2006 Feb;51(2):134-45. Epub 2005 Aug 18.
Copyright	Copyright © 2005 Elsevier Ltd. All rights reserved.
Comments	The complete cDNA template sequence was obtained from the information provided in the publication as described in Havens et al. 2006.