GEISHA 2.0

NCBI Nucleotide Hit

Ensembl Genome Map contig view

Complete Sequence

Stage

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Location (click to highlight)

Comments (click to highlight)

1-3

stage 3

Area Pellucida

Hypoblast

4-6

stage 4

stage 6

7-12

stage 7

stage 10

stage 11

13-16

stage 14

stage 16

Probe 2

GEISHA Id HEX.Bertocchini.2008

NCBI Ensembl

Gene Name HHEX HHEX_CHICK

Aliases PROBOX, HHEX, hematopoietically expressed homeobox, Official

Gene Description hematopoietically expressed homeobox Homeobox protein PRH (Hematopoietically-expressed homeobox). [Source:Uniprot/SWISSPROT;Acc:Q05502]

Gene Ontology

NCBI Nucleotide Hit

Ensembl Genome Map contig view

Citation Federica Bertocchini, Claudio D Stern (2008). A differential screen for genes expressed in the extraembryonic endodermal layer of pre-primitive streak stage chick embryos reveals expression of Apolipoprotein A1 in hypoblast, endoblast and endoderm. Gene Expression Patterns, Volume 8, Issues 7-8, September 2008, Pages 477-480, ISSN 1567-133X, DOI: 10.1016/j.gep.2008.07.001.

Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205252).

Complete Sequence

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

stage 1

Hypoblast

Stage XIV EG&K

Probe 3

GEISHA Id Hex.Chapman.2002

NCBI Ensembl

Gene Name HHEX HHEX_CHICK

Aliases PROBOX, HHEX, hematopoietically expressed homeobox, Official

Gene Description hematopoietically expressed homeobox Homeobox protein PRH (Hematopoietically-expressed homeobox). [Source:Uniprot/SWISSPROT;Acc:Q05502]

Gene Ontology

NCBI Nucleotide Hit

Ensembl Genome Map contig view

Citation Chapman SC, Schubert FR, Schoenwolf GC, Lumsden A. Analysis of spatial and temporal gene expression patterns in blastula and gastrula stage chick embryos. Dev Biol. 2002 May 1;245(1):187-99.

Complete Sequence

Chordin expression in the notochord shown in red.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

1-3

stage 1

stage 3

4-6

stage 4

stage 5

stage 6

Prechordal Plate

Probe 4

GEISHA Id	Hex.Chapman.2008
	NCBI	Ensembl
Gene Name		HHEX_CHICK
Gene Description		Homeobox protein PRH (Hematopoietically-expressed homeobox). [Source:Uniprot/SWISSPROT;Acc:Q05502]
Gene Ontology		show GO:0001889 liver development IEA GO:0003677 DNA binding IEA GO:0003700 transcription factor activity IEA GO:0005515 protein binding IEA GO:0005634 nucleus IEA GO:0006355 regulation of transcription, DNA-dependent IEA GO:0007275 multicellular organismal development IEA GO:0009887 organ morphogenesis IEA GO:0030878 thyroid gland development IEA GO:0030900 forebrain development IEA GO:0035050 embryonic heart tube development IEA GO:0042127 regulation of cell proliferation IEA GO:0043565 sequence-specific DNA binding IEA GO:0045449 regulation of transcription IEA
Ensembl Genome Map	contig view
Comments	Images Provided by Susan Chapman. Insufficient information provided to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_205252).
Complete Sequence	show GCGGCGGCGGTGGCAGCAGCCGGCGGCCGCGCTCGGGGCCGCTCTCCGAGGGGCGGCCGGGCCGCGGGGGGCCGGGGAG CCGCGCCATGCAGTATCAGGCGCCGGGCGCGGCTCCGGCGGCGGCCCTGGGCGTCGGCGTCCCTCTGTACGCGCCCACG CCGCTGCTGCAGCCCGCGCACCCCACGCCCTTCTACATCGAGGACATCCTGGGCCGCGGCCCCGCCGCCGCGCCGGCCC CCCACTCCCTGCCCGCCCCGCCGCCGCCGACGCTGCCGTCGCCCAACTCCTCCTTCACCAGCCTGGTGGCCCCGTACCG GACCCCCGTCTACGAGCCGACCCCCATCCACCCGGCCTTCTCTCACCACCTCGCCGCCACCTACGGCACCGGCGCTTAC GCCGGGCCCCTCTACTCCTTTCCCCGCGCCGTCGGCGACTACACGCACGCACTGATCCGCCAGGACCCCCTGGGAAAGC CGCTGCTGTGGAGCCCCTTCATCCAGCGGCCGCTGCATAAGAGGAAGGGTGGGCAGGTGCGCTTCTCCAACGAGCAGAC CATCGAGCTGGAGAAGAAGTTCGAGACGCAGAAATACCTCTCCCCGCCCGAGAGGAAGCGCCTGGCCAAGCTGCTGCAG CTCAGCGAGCGCCAGGTCAAAACGTGGTTCCAGAACCGCAGAGCCAAATGGAGGCGACTGAAGCAGGAGAACCCCCAGG CCACCAAAAAGGAGGAGGCGGAAGGCACCGGCGATCACGGCGACCCTCGGTCGGAGGGCAGCCCCAGCCCCGCGGGGGG GGGCGAGGCCGAGCCGCAGGACAGCCCTTCGGCCGCCTCGCAGGAGGACCCCGAGTCCGACGTCTCCGACGACTCCGAC CAGGAGGTGGACATCGAGGGCGACAAAGGCTTCTACAGCGCCACACGCTGACGGCCCGCGGGCACGGAGCCGAGCTCGG CTTGCGCTGTCCCGGGACTGCGGGAAGGAGGATTTTATGACGGGAGAGGACCTTCACCATTCCGCCGAAAGACAAAGAA GCACGAACGGACTCGTTCTGTAATAATCTGAGAAAGAAAAGATATTCGTTCTGCAAACGGTCCGTTTTTTTTTGGCAGA TCTCTGATTTGATTGTAGGGACTGATCGGTGGTTTGTATTTACTGTGTAAGATCTGTGTGTATGTTGATTGGTGCTCTG ACCGGGACACAGCGCTGTGCCCATCTCCGGCTGCTGGAACCCCCCTCTTCCCCAGCTCGTGTAGTGGGGGAGCACTGAG GGCACCACCGTGCCTTTGTGTGTGCGAACGAATCTGCTTTAAATGGAGTAATTTAAGTGTCCTTCGCAGGCAGAGAAAT GTATTCTGTGCCATAGAGAGGGATTGGAGCATCCCGAGAGTGCCTTACCCCACCCAGGACCTGCAGCTGCATCCCCCGG AAGGATCCCCCCTCACCGGGCAGAGGCTGTGGGCACGTTCCGTTTTGCTCTTGATGGAGTGAAATGTCCCTCATCGCAT TTTGGAGGATTTTGCCCCACAATCTGTGTGGTTCCATTTGCAGGGAAAAAAAAAAACAAAACAAAAACAAAAACCAAAC ACAGCAACAAACCAACCCAGGCTATTTTTTTCCTTGACAAATCTGTCGTGCTGTCCCCCAGATTTCCCATTTCAGAAGG AAATGAGGGGCTGATAGGGCACTGCGAGGCGCAGTGTGACAGCGGGCACCCGTGCCTGGCGTGTCCCTCTCTGCTCGTG TACATAGCAGTTTGCCTTAAAAGTCTTTGCGGTTTTATACCTCACATTGTTCATATTTTGTACATATTGGTTTAAAAGA AAAAAAAAAAAAGGAATCAAAAACTGGT

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

1-3

stage 1

stage 2

stage 3

4-6

stage 4

stage 5

7-12

stage 8

stage 9

stage 11

stage 12

Liver precursor endoderm

13-14

stage 14

Probe 5

GEISHA Id HEX.Foley.2000

NCBI Ensembl

Gene Name HHEX HHEX_CHICK

Aliases PROBOX, HHEX, hematopoietically expressed homeobox, Official

Gene Description hematopoietically expressed homeobox Homeobox protein PRH (Hematopoietically-expressed homeobox). [Source:Uniprot/SWISSPROT;Acc:Q05502]

Gene Ontology

NCBI Nucleotide Hit

Ensembl Genome Map contig view

Citation Foley AC, Skromne I, Stern CD. Reconciling different models of forebrain induction and patterning: a dual role for the hypoblast. Development. 2000 Sep;127(17):3839-54.

Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205252).

Complete Sequence

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

1-3

stage 1

stage 2

stage 4

Probe 6

GEISHA Id HEX.Ishii.2007

NCBI Ensembl

Gene Name HHEX HHEX_CHICK

Aliases PROBOX, HHEX, hematopoietically expressed homeobox, Official

Gene Description hematopoietically expressed homeobox Homeobox protein PRH (Hematopoietically-expressed homeobox). [Source:Uniprot/SWISSPROT;Acc:Q05502]

Gene Ontology

NCBI Nucleotide Hit

Ensembl Genome Map contig view

Citation Ishii Y, Langberg JD, Hurtado R, Lee S, Mikawa T. Induction of proepicardial marker gene expression by the liver bud. Development. 2007 Oct;134(20):3627-37. Epub 2007 Sep 12.

Copyright Published by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Permission granted by T. Mikawa.

Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205252).

Complete Sequence

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 11

stage 12

13-16

stage 14

stage 16

Probe 7

GEISHA Id Hex.Klewer.2006

NCBI Ensembl

Gene Name HHEX HHEX_CHICK

Aliases PROBOX, HHEX, hematopoietically expressed homeobox, Official

Gene Description hematopoietically expressed homeobox Homeobox protein PRH (Hematopoietically-expressed homeobox). [Source:Uniprot/SWISSPROT;Acc:Q05502]

Gene Ontology

NCBI Nucleotide Hit

Ensembl Genome Map contig view

Citation Klewer SE, Yatskievych T, Pogreba K, Stevens MV, Antin PB, Camenisch TD. Has2 expression in heart forming regions is independent of BMP signaling. Gene Expr Patterns. 2006 Jun;6(5):462-70. Epub 2006 Feb 3.

Comments According to authors , "... Hex (full-length, a the gift of G.H. Goodwin, Institute of Cancer Research, London (Zhang et al., 2004)). " As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205252)

Complete Sequence

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

stage 7

Blood Islands

Lateral Plate Mesoderm

Cardiac crescent

Probe 8

GEISHA Id Hex.Yanai.2005

NCBI Ensembl

Gene Name HHEX HHEX_CHICK

Aliases PROBOX, HHEX, hematopoietically expressed homeobox, Official

Gene Description hematopoietically expressed homeobox Homeobox protein PRH (Hematopoietically-expressed homeobox). [Source:Uniprot/SWISSPROT;Acc:Q05502]

Gene Ontology

NCBI Nucleotide Hit

Ensembl Genome Map contig view

Citation Yanai M, Tatsumi N, Endo F, Yokouchi Y. Analysis of gene expression patterns in the developing chick liver. Dev Dyn. 2005 Jul;233(3):1116-22.

Complete Sequence

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 12

Endoderm

Head Process

13-18

stage 17

Thyroid

19-24

stage 22

25-30

stage 25

Endoderm

31-42

stage 36

stage 39

stage 42

Endoderm