GEISHA - A Chicken Embryo Gene Expression Database
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ACTA2
actin, alpha 2, smooth muscle, aorta

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolACTA2
Official Full Nameactin, alpha 2, smooth muscle, aorta
CGNC ID52051
also known asasma, actin, aortic smooth muscle|alpha-actin, Smooth muscle gamma actin, Alpha- actin-3, actin, gamma-enteric smooth muscle, gamma-enteric smooth muscle actin, αSMA
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001031229
PolypeptideNP_001026400
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.4530
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human59ENSG00000107796MIM:611788MIM:102620
Mouse
Xenopus496696, 431847493936
Zebrafish322509ENSDARG00000045180ZDB-GENE-030131-1229ZFIN:ZDB-GENE-030131-1229
Gene Ontology
Molecular FunctionATP binding
Biological Process
Cellular Componentcytoplasm, cytoskeleton
Links to other databases
Entrez Gene423787
Ensembl Gene
KEGGgga:423787

Entry 1

GEISHA IdSm.musclealphaactin.Colas.2000Data SourcePublication
Complete cDNA Template Probeshow
ATGTGTGAGGAGGAGGACAGCACTGCCCTTGTTTGTGACAATGGCTCAGGGCTCTGTAAAGCTGGCTTTGCCGGGGATG
ATGCTCCAAGAGCAGTTTTCCCTTCCATCGTGGGTCGTCCCAGGCACCAGGGTGTGATGGTTGGTATGGGTCAAAAAGA
CAGCTATGTAGGTGATGAGGCTCAAAGCAAGAGAGGAATCCTGACCTTGAAATACCCCATAGAACATGGCATCATTACC
AACTGGGATGACATGGAGAAGATCTGGCATCACTCCTTCTATAATGAGCTCCGTGTTGCACCTGAGGAGCACCCAACTC
TGCTGACTGAAGCACCACTGAATCCCAAAGCCAATCGAGAGAAAATGACCCAGATTATGTTTGAGACTTTCAATGTGCC
AGCCATGTATGTAGCTATTCAAGCTGTTCTGTCCCTGTATGCTTCTGGGCGTACTACAGGGATT
CitationColas JF, Lawson A, Schoenwolf GC. Evidence that translation of smooth muscle alpha-actin mRNA is delayed in the chick promyocardium until fusion of the bilateral heart-forming regions. Dev Dyn. 2000 Jun;218(2):316-30.
CopyrightCopyright © 2000 Wiley-Liss, Inc.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 5
stage 6
Heart
Lateral Plate Mesoderm
cardiogenic mesoderm
cardiogenic mesoderm.
7-12
stage 7
stage 7
stage 8
stage 8
stage 9
stage 9
stage 10
stage 11
Anterior Intestinal Portal
Heart
Heart Tube
Lateral Plate Mesoderm
Mesoderm, early
Myocardium
Somatopleure
Splanchnic Mesoderm
Ventricles
bilateral cardiogenic plates
lateral extraembryonic mesoderm
pr, promyocardium
sp, splanchnic mesoderm
splanchnic cardiac mesoderm (=) promyocardium
13-15
stage 15
Blood Vessels
Heart
Heart Tube
 

Entry 2

GEISHA IdUsmaar.Lopez-Sanchez.2009Data SourcePublication
Complete cDNA Template Probeshow
ATGTGTGAGGAGGAGGACAGCACTGCCCTTGTTTGTGACAATGGCTCAGGGCTCTGTAAAGCTGGCTTTGCCGGGGATG
ATGCTCCAAGAGCAGTTTTCCCTTCCATCGTGGGTCGTCCCAGGCACCAGGGTGTGATGGTTGGTATGGGTCAAAAAGA
CAGCTATGTAGGTGATGAGGCTCAAAGCAAGAGAGGAATCCTGACCTTGAAATACCCCATAGAACATGGCATCATTACC
AACTGGGATGACATGGAGAAGATCTGGCATCACTCCTTCTATAATGAGCTCCGTGTTGCACCTGAGGAGCACCCAACTC
TGCTGACTGAAGCACCACTGAATCCCAAAGCCAATCGAGAGAAAATGACCCAGATTATGTTTGAGACTTTCAATGTGCC
AGCCATGTATGTAGCTATTCAAGCTGTTCTGTCCCTGTATGCTTCTGGGCGTACTACAGGGATTGTGCTTGACTCTGGG
GATGGTGTCACCCACAACGTGCCCATTTATGAAGGCTACGCTTTGCCACATGCCATCATGCGTCTGGACCTGG
CitationLopez-Sanchez C, Garcia-Masa N, Gañan CM, Garcia-Martinez V. Movement and commitment of primitive streak precardiac cells during cardiogenesis. Int J Dev Biol. 2009;53(8-10):1445-55.
CopyrightReprinted from Int. J. Dev. Biol. Copyright (2009), with permission from UBC Press. All rights reserved.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_001031229.1; first 547 nt)
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-8
stage 8
Heart
Splanchnic Mesoderm
 

Entry 3

GEISHA IdαSMA.LeGuen.2009Data SourcePublication
Complete cDNA Template Probeshow
ATGTGTGAGGAGGAGGACAGCACTGCCCTTGTTTGTGACAATGGCTCAGGGCTCTGTAAAGCTGGCTTTGCCGGGGATG
ATGCTCCAAGAGCAGTTTTCCCTTCCATCGTGGGTCGTCCCAGGCACCAGGGTGTGATGGTTGGTATGGGTCAAAAAGA
CAGCTATGTAGGTGATGAGGCTCAAAGCAAGAGAGGAATCCTGACCTTGAAATACCCCATAGAACATGGCATCATTACC
AACTGGGATGACATGGAGAAGATCTGGCATCACTCCTTCTATAATGAGCTCCGTGTTGCACCTGAGGAGCACCCAACTC
TGCTGACTGAAGCACCACTGAATCCCAAAGCCAATCGAGAGAAAATGACCCAGATTATGTTTGAGACTTTCAATGTGCC
AGCCATGTATGTAGCTATTCAAGCTGTTCTGTCCCTGTATGCTTCTGGGCGTACTACAGGGATTGTGCTTGACTCTGGG
GATGGTGTCACCCACAACGTGCCCATTTATGAAGGCTACGCTTTGCCACATGCCATCATGCGTCTGGACCTGGCTGGCC
GTGACCTGACAGACTACCTCATGAAGATCCTGAGCGAACGTGGCTACTCCTTTGTGACCACTGCGGAGCGTGAAATTGT
CCGTGACATCAAGGAGAAACTGTGTTATGTGGCCCTGGACTTTGAAAACGAGATGGCCACTGCTGCCTCTTCCTCCTCT
CTGGAAAAAAGCTATGAGCTTCCTGATGGCCAGGTCATCACCATTGGAAATGAACGGTTCCGCTGCCCAGAGACTCTCT
TCCAGCCATCTTTCATTGGCATGGAGTCCGCTGGCATTCATGAAACCACTTACAACAGCATCATGAAGTGTGACATAGA
CATCAGAAAGGATCTTTATGCCAACAATGTGCTTTCTGGAGGCACTACAATGTACCCAGGCATTGCAGACAGAATGCAA
AAGGAAATAACTGCTCTAGCTCCCAGCACCATGAAGATCAAGATCATTGCTCCTCCTGAACGTAAGTACTCCGTCTGGA
TTGGAGGCTCTATTCTTGCCTCCCTCTCCACCTTCCAGCAGATGTGGATCAGCAAACAGGAATATGATGAGGCTGGCCC
ATCCATCGTTCACCGCAAATGCTTTTAA
CitationLe Guen L, Notarnicola C, de Santa Barbara P. Intermuscular tendons are essential for the development of vertebrate stomach. Development. 2009 Mar;136(5):791-801.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_001031229.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-35
stage 35
stage 35
Splanchnic Mesoderm
Stomach
smooth muscle cells (SMC)

Entry 4

GEISHA IdACTAsmooth.Ruzicka.1988Data SourcePublication
Complete cDNA Template Probeshow
ATGTGTGAGGAGGAGGACAGCACTGCCCTTGTTTGTGACAATGGCTCAGGGCTCTGTAAAGCTGGCTTTGCCGGGGATG
ATGCTCCAAGAGCAGTTTTCCCTTCCATCGTGGGTCGTCCCAGGCACCAGGGTGTGATGGTTGGTATGGGTCAAAAAGA
CAGCTATGTAGGTGATGAGGCTCAAAGCAAGAGAGGAATCCTGACCTTGAAATACCCCATAGAACATGGCATCATTACC
AACTGGGATGACATGGAGAAGATCTGGCATCACTCCTTCTATAATGAGCTCCGTGTTGCACCTGAGGAGCACCCAACTC
TGCTGACTGAAGCACCACTGAATCCCAAAGCCAATCGAGAGAAAATGACCCAGATTATGTTTGAGACTTTCAATGTGCC
AGCCATGTATGTAGCTATTCAAGCTGTTCTGTCCCTGTATGCTTCTGGGCGTACTACAGGGATTGTGCTTGACTCTGGG
GATGGTGTCACCCACAACGTGCCCATTTATGAAGGCTACGCTTTGCCACATGCCATCATGCGTCTGGACCTGGCTGGCC
GTGACCTGACAGACTACCTCATGAAGATCCTGAGCGAACGTGGCTACTCCTTTGTGACCACTGCGGAGCGTGAAATTGT
CCGTGACATCAAGGAGAAACTGTGTTATGTGGCCCTGGACTTTGAAAACGAGATGGCCACTGCTGCCTCTTCCTCCTCT
CTGGAAAAAAGCTATGAGCTTCCTGATGGCCAGGTCATCACCATTGGAAATGAACGGTTCCGCTGCCCAGAGACTCTCT
TCCAGCCATCTTTCATTGGCATGGAGTCCGCTGGCATTCATGAAACCACTTACAACAGCATCATGAAGTGTGACATAGA
CATCAGAAAGGATCTTTATGCCAACAATGTGCTTTCTGGAGGCACTACAATGTACCCAGGCATTGCAGACAGAATGCAA
AAGGAAATAACTGCTCTAGCTCCCAGCACCATGAAGATCAAGATCATTGCTCCTCCTGAACGTAAGTACTCCGTCTGGA
TTGGAGGCTCTATTCTTGCCTCCCTCTCCACCTTCCAGCAGATGTGGATCAGCAAACAGGAATATGATGAGGCTGGCCC
ATCCATCGTTCACCGCAAATGCTTTTAA
CitationRuzicka DL, Schwartz RJ. Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation. J Cell Biol. 1988 Dec;107(6 Pt 2):2575-86.
Copyright© The Rockefeller University Press,
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_001031229.1 ).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 8
stage 8
stage 10
stage 10
Heart Tube
Unlabeled
 
13-18
stage 13
stage 13
stage 14
stage 14
Outflow Tract
 
25-29
stage 29
Blood Vessels
 

Entry 5

GEISHA IdACTA2.Rada.2012Data SourcePublication
Complete cDNA Template Probeshow
ATGTGTGAGGAGGAGGACAGCACTGCCCTTGTTTGTGACAATGGCTCAGGGCTCTGTAAAGCTGGCTTTGCCGGGGATG
ATGCTCCAAGAGCAGTTTTCCCTTCCATCGTGGGTCGTCCCAGGCACCAGGGTGTGATGGTTGGTATGGGTCAAAAAGA
CAGCTATGTAGGTGATGAGGCTCAAAGCAAGAGAGGAATCCTGACCTTGAAATACCCCATAGAACATGGCATCATTACC
AACTGGGATGACATGGAGAAGATCTGGCATCACTCCTTCTATAATGAGCTCCGTGTTGCACCTGAGGAGCACCCAACTC
TGCTGACTGAAGCACCACTGAATCCCAAAGCCAATCGAGAGAAAATGACCCAGATTATGTTTGAGACTTTCAATGTGCC
AGCCATGTATGTAGCTATTCAAGCTGTTCTGTCCCTGTATGCTTCTGGGCGTACTACAGGGATTGTGCTTGACTCTGGG
GATGGTGTCACCCACAACGTGCCCATTTATGAAGGCTACGCTTTGCCACATGCCATCATGCGTCTGGACCTGGCTGGCC
GTGACCTGACAGACTACCTCATGAAGATCCTGAGCGAACGTGGCTACTCCTTTGTGACCACTGCGGAGCGTGAAATTGT
CCGTGACATCAAGGAGAAACTGTGTTATGTGGCCCTGGACTTTGAAAACGAGATGGCCACTGCTGCCTCTTCCTCCTCT
CTGGAAAAAAGCTATGAGCTTCCTGATGGCCAGGTCATCACCATTGGAAATGAACGGTTCCGCTGCCCAGAGACTCTCT
TCCAGCCATCTTTCATTGGCATGGAGTCCGCTGGCATTCATGAAACCACTTACAACAGCATCATGAAGTGTGACATAGA
CATCAGAAAGGATCTTTATGCCAACAATGTGCTTTCTGGAGGCACTACAATGTACCCAGGCATTGCAGACAGAATGCAA
AAGGAAATAACTGCTCTAGCTCCCAGCACCATGAAGATCAAGATCATTGCTCCTCCTGAACGTAAGTACTCCGTCTGGA
TTGGAGGCTCTATTCTTGCCTCCCTCTCCACCTTCCAGCAGATGTGGATCAGCAAACAGGAATATGATGAGGCTGGCCC
ATCCATCGTTCACCGCAAATGCTTTTAA
CitationRada JA, Hollaway LR, Lam W, Li N, Napoli JL. Identification of RALDH2 as a visually regulated retinoic acid synthesizing enzyme in the chick choroid. Invest Ophthalmol Vis Sci. 2012 Mar 26;53(3):1649-62.
CopyrightCopyright © Association for Research in Vision and Ophthalmology
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_001031229.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-44
stage 44
stage 44
stage 44
stage 44
stage 44
stage 44
stage 44
Eye
+44 post-hatch chick
contralateral control eye

Entry 6

GEISHA IdACTA2.Anderson.2020Data SourceDirect Submission
Complete cDNA Template Probeshow
CTACAATGTACCCGGGCATTGCAGACAGAATGCAAAAGGAAATAACTGCTCTAGCTCCCAGCACCATGAAGATCAAGAT
CATTGCTCCTCCTGAACGTAAGTACTCCGTCTGGATTGGAGGCTCTATTCTTGCCTCCCTCTCCACCTTCCAGCAGATG
TGGATCAGCAAACAGGAATATGATGAGGCTGGCCCATCCATCGTTCACCGCAAATGCTTTTAAATCGCTTTATACTTCT
ATGTCTTTTTAGCATATTACTGTGAATGTATTCAGGAAAATACATTCTTAAAATTTCATTCCATAAATCTTTCATCGTA
ATGGCTGGTTAATTGGATACGGTGTATTTTTTGGAATAAATTTTAAATATGCAAATGAAATTGCTGCTCCTAGTTTAGA
GATGCAGTTGTGGAGTTGCCATTACAGCTGGTGCGAAGCTCCATCTCGTGGCGTAAATTTGCTACTGCGCTGTGGGCGT
AGAAGTGGTACCTGTTGTCCAGTGGTATCAACTCCAGAAAACGCTCAGCTCCCAGCCTGCACGGTGCCAGCGTTCAGCC
TCGGTATGCATTTCAGTCTGCAAGCAGAACTAGTCATGGTGTTCCCAAAGTTCTGGGCAGCAGCAGAGGGGCACAGCAT
CTGCTTGGTACCAGGAGGAGCACGTGCACTCTGCTTTGCATCTGCTCTATCCAGAAATATTATCTGTCCACATCACTTC
TCAGTTCACAGCTACCATGCTGGAAAAGGCACTTCTTATACCCTACGGCCCAGAAGTGTACGATGCTTTCTATATCTTT
TCATGGTTGTTTTCTTTT
CommentsImages Provided by Claire Anderson. Related article: Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5. (PMID: 31283921)
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 12
stage 12
stage 12
Amnion
Atria
Blood Vessels
Endoderm
Extraembryonic Blood Vessels
Lateral Plate Mesoderm
Myocardium
Outflow Tract
Sinus Venosus
Somites
Ventricles
extraembryonic endoderm
extraembryonic mesoderm
 

Entry 7

GEISHA IdACTA2.Anderson.2019Data SourcePublication
Complete cDNA Template Probeshow
CTACAATGTACCCGGGCATTGCAGACAGAATGCAAAAGGAAATAACTGCTCTAGCTCCCAGCACCATGAAGATCAAGAT
CATTGCTCCTCCTGAACGTAAGTACTCCGTCTGGATTGGAGGCTCTATTCTTGCCTCCCTCTCCACCTTCCAGCAGATG
TGGATCAGCAAACAGGAATATGATGAGGCTGGCCCATCCATCGTTCACCGCAAATGCTTTTAAATCGCTTTATACTTCT
ATGTCTTTTTAGCATATTACTGTGAATGTATTCAGGAAAATACATTCTTAAAATTTCATTCCATAAATCTTTCATCGTA
ATGGCTGGTTAATTGGATACGGTGTATTTTTTGGAATAAATTTTAAATATGCAAATGAAATTGCTGCTCCTAGTTTAGA
GATGCAGTTGTGGAGTTGCCATTACAGCTGGTGCGAAGCTCCATCTCGTGGCGTAAATTTGCTACTGCGCTGTGGGCGT
AGAAGTGGTACCTGTTGTCCAGTGGTATCAACTCCAGAAAACGCTCAGCTCCCAGCCTGCACGGTGCCAGCGTTCAGCC
TCGGTATGCATTTCAGTCTGCAAGCAGAACTAGTCATGGTGTTCCCAAAGTTCTGGGCAGCAGCAGAGGGGCACAGCAT
CTGCTTGGTACCAGGAGGAGCACGTGCACTCTGCTTTGCATCTGCTCTATCCAGAAATATTATCTGTCCACATCACTTC
TCAGTTCACAGCTACCATGCTTGGAAAAAGGCACTTCTTATACCCTAACGGCCAGAAGTGTACGATGCTTTTCTATATC
TTTCATGGTAGTTACTTTTGCTTTGTTGCCTATTAAAATAAAACTCTCCTTCTGG
CitationAnderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
CopyrightCopyright © 2019 Elsevier Inc. All rights reserved.
CommentsThe complete cDNA template sequence was obtained from the information from the publication as described in Anderson et al. 2019.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 12
Outflow Tract
 
all
 
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.4530

Mouse

Emage
Eurexpress
MGI GXD

Frog

Xenbase493936

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030131-1229
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