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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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ACTA1
actin, alpha 1, skeletal muscle

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	ACTA1
Official Full Name	actin, alpha 1, skeletal muscle
CGNC ID	8420
also known as	actin, alpha skeletal muscle\|a-actin\|alpha-actin-1, Alpha-actin-1, Actin, alpha skeletal muscle
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_001031063
Polypeptide	NP_001026234

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	58	ENSG00000143632	MIM:102610	MIM:102610
Mouse	11459	ENSMUSG00000031972	All phenotypic alleles (1):Targeted, knock-out(1)	MGI:87902
Xenopus	448346, 432314, 394698, 379752			491937, 480346
Zebrafish	407658, 550445	ENSDARG00000055618, ENSDARG00000036371	ZDB-GENE-030131-55, ZDB-GENE-050417-267	ZFIN:ZDB-GENE-030131-55, ZFIN:ZDB-GENE-050417-267

Gene Ontology

Molecular Function	ATP binding
Biological Process	skeletal muscle fiber development, skeletal muscle thin filament assembly
Cellular Component	actin filament, extracellular vesicular exosome, stress fiber, striated muscle thin filament

Links to other databases

Entrez Gene	421534
Ensembl Gene	ENSGALG00000011086
KEGG	gga:421534

Entry 1

GEISHA Id	ACTA1.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	GAACACGGCATCATCACAAACTG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGATCTGCTGGAAGGTGGACAGGGAG	cDNA Template Length	851
Forward cDNA Template Probe	show AAGAAGGAACCACCGAATCCAGNACAGAGTACTTGCGCTCAGGGTGGGGCAATGATCTTGATCTTCATTGGTGCTGGGG GCCAGGGCTGTGATCTCCTTTTGCATGCGGTCAGCAATACCTGGGTACATGGTGGTACCCCCAGACATGACGTTGTTGG CATACAGGTCCTTCCTGATGTCAATGTCGCATTTCATGATGCTGTTGTAAGTTGTCTCATGGATCCCAGCGGACTCCAT ACCAATGAAGGAAGGCTGGAANAGGGTTTCTGGGCANCGGAAACGCTCATTGCCGATGGTGATGACCTGCCCATCAGGC AGCTCATAGCTCTTCTCCAGGGAGGAGGAGGAGGCAGCGGTGGCCATCTCGTTCTCAAAGTCCAGAGCCACATAGCACA GCTTCTCCTTGATGTCACGGACAATCTCACGTTCAGCTGTGGTGACAAAGGAATAGCCACGCTCAGTCAGGATCTTCAT CAGGTAGTCAGTGAGGTCGCGGCCAGCCAGATCCAAGCGCATGATGGCATGGGGCAGGGCATACCCTTCATAGATGGGG ACGTTGTGTGTCACACCATCGCCGGAGTCCAGCACAATACCGGTGGTACGGCCAGAGGCATACAGGGACAGCACAGCCT GGATGGCCACGTACATGGCGGGCACNTTAAAGGTCTCAAACATGATTTGGGTCATCTTTTCACGGTTAGCTTTGGGATT AAGGGGGGCCTCANTGANCAGGGTGGGGTGCTCCTCAGGGGCCACACGCANCTCATTGTAAAAGGTGTGGTGCCAAATC TTCTCCATGTCGTCCCAGTTTGTGATGAGCCCNTGTTCAA

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 5

Area Opaca
Early Endoderm
Early Mesoderm
Ectoderm
Endoderm
Extraembryonic Mesoderm
Lateral Plate Mesoderm
Neural Plate/Tube
Primitive Streak

7-12

stage 8

stage 9

stage 11

Amnion
Blood Vessels
Ectoderm
Endoderm
Extraembryonic
Extraembryonic Blood Vessels
Extraembryonic Mesoderm
Forebrain
Heart
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Notochord
Primitive Streak
Somites
Ubiquitous

13-18

stage 14

stage 17

stage 18

Ectoderm
Endoderm
Extraembryonic Blood Vessels
Heart
Lateral Plate Mesoderm
Sclerotome
Somites
Spinal Cord
Ubiquitous

Entry 2

GEISHA Id	ACTA1.Bertola.2008	Data Source	Publication
Complete cDNA Template Probe	show ATGTGTGACGAGGACGAGACCACCGCGCTCGTGTGCGACAACGGCTCCGGCCTAGTGAAGGCTGGCTTCGCCGGGGATG ACGCCCCCAGGGCCGTGTTCCCTTCCATCGTGGGCCGGCCCCGCCACCAAGGTGTCATGGTGGGTATGGGTCAGAAGGA CTCCTACGTAGGAGATGAAGCTCAGAGCAAGAGAGGTATCCTCACCCTGAAGTACCCCATTGAACACGGCATCATCACA AACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCCCCTGAGGAGCACCCCACCC TGCTCACTGAGGCCCCCCTTAATCCCAAAGCTAACCGTGAAAAGATGACCCAAATCATGTTTGAGACCTTTAACGTGCC CGCCATGTACGTGGCCATCCAAGCTGTGCTGTCCCTGTATGCCTCTGGCCGTACCACCGGTATTGTGCTGGACTCCGGC GATGGTGTGACACACAACGTCCCCATCTATGAAGGGTATGCCCTGCCCCATGCCATCATGCGCTTGGATCTGGCTGGCC GCGACCTCACTGACTACCTGATGAAGATCCTGACTGAGCGTGGCTATTCCTTTGTCACCACAGCTGAACGTGAGATTGT CCGTGACATCAAGGAGAAGCTGTGCTATGTGGCTCTGGACTTTGAGAACGAGATGGCCACCGCTGCCTCCTCCTCCTCC TTGGAGAAGAGCTATGAGCTGCCTGATGGGCAGGTCATCACCATCGGCAATGAGCGTTTCCGCTGCCCAGAAACCCTCT TCCAGCCTTCCTTCATTGGTATGGAGTCCGCTGGGATCCATGAGACAACTTACAACAGCATCATGAAATGCGACATTGA CATCAGGAAGGACCTGTATGCCAACAACGTCATGTCTGGGGGTACCACCATGTACCCAGGTATTGCTGACCGCATGCAA AAGGAGATCACAGCCCTGGCCCCCAGCACAATGAAGATCAAGATCATTGCCCCACCTGAGCGCAAGTACTCTGTCTGGA TCGGTGGCTCCATCTTGGCCTCCCTGTCCACCTTCCAGCAGATGTGGATCACAAAGCAGGAGTATGATGAAGCCGGCCC ATCCATTGTCCACCGTAAATGCTTCTAA
Citation	Bertola LD, Ott EB, Griepsma S, Vonk FJ, Bagowski Developmental expression of the alpha-skeletal actin gene. CP.BMC Evol Biol. 2008 Jun 2;8:166.
Copyright	© 2008 Bertola et al; licensee BioMed Central Ltd.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_001031063).

Stage

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Location (click to highlight)

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19-24

stage 20

Heart
Lens
Limb Buds
Mesencephalon
Metencephalon
Pharyngeal Arches and Clefts
Somites

stage 25

Ear/Otic Placode
Heart
Limb Buds
Pharyngeal Arches and Clefts
Somites

Entry 3

GEISHA Id	ACTAskel.Ruzicka.1988	Data Source	Publication
Complete cDNA Template Probe	show ATGTGTGACGAGGACGAGACCACCGCGCTCGTGTGCGACAACGGCTCCGGCCTAGTGAAGGCTGGCTTCGCCGGGGATG ACGCCCCCAGGGCCGTGTTCCCTTCCATCGTGGGCCGGCCCCGCCACCAAGGTGTCATGGTGGGTATGGGTCAGAAGGA CTCCTACGTAGGAGATGAAGCTCAGAGCAAGAGAGGTATCCTCACCCTGAAGTACCCCATTGAACACGGCATCATCACA AACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCCCCTGAGGAGCACCCCACCC TGCTCACTGAGGCCCCCCTTAATCCCAAAGCTAACCGTGAAAAGATGACCCAAATCATGTTTGAGACCTTTAACGTGCC CGCCATGTACGTGGCCATCCAAGCTGTGCTGTCCCTGTATGCCTCTGGCCGTACCACCGGTATTGTGCTGGACTCCGGC GATGGTGTGACACACAACGTCCCCATCTATGAAGGGTATGCCCTGCCCCATGCCATCATGCGCTTGGATCTGGCTGGCC GCGACCTCACTGACTACCTGATGAAGATCCTGACTGAGCGTGGCTATTCCTTTGTCACCACAGCTGAACGTGAGATTGT CCGTGACATCAAGGAGAAGCTGTGCTATGTGGCTCTGGACTTTGAGAACGAGATGGCCACCGCTGCCTCCTCCTCCTCC TTGGAGAAGAGCTATGAGCTGCCTGATGGGCAGGTCATCACCATCGGCAATGAGCGTTTCCGCTGCCCAGAAACCCTCT TCCAGCCTTCCTTCATTGGTATGGAGTCCGCTGGGATCCATGAGACAACTTACAACAGCATCATGAAATGCGACATTGA CATCAGGAAGGACCTGTATGCCAACAACGTCATGTCTGGGGGTACCACCATGTACCCAGGTATTGCTGACCGCATGCAA AAGGAGATCACAGCCCTGGCCCCCAGCACAATGAAGATCAAGATCATTGCCCCACCTGAGCGCAAGTACTCTGTCTGGA TCGGTGGCTCCATCTTGGCCTCCCTGTCCACCTTCCAGCAGATGTGGATCACAAAGCAGGAGTATGATGAAGCCGGCCC ATCCATTGTCCACCGTAAATGCTTCTAA
Citation	Ruzicka DL, Schwartz RJ. Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation. J Cell Biol. 1988 Dec;107(6 Pt 2):2575-86.
Copyright	© The Rockefeller University Press,
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_001031063.1).