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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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ACTB
actin, beta

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	ACTB
Official Full Name	actin, beta
CGNC ID	49855
also known as	Bact, actin, actin, cytoplasmic 1\|Bact; actin\|beta-actin\|cytoplasmic 1
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205518
Polypeptide	NP_990849
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.48207

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	41885			FBgn0000047
Human	60	ENSG00000075624	MIM:607371	MIM:102630
Mouse	11461	ENSMUSG00000029580	All phenotypic alleles (12):Targeted, knock-out(2) Targeted, other(10)	MGI:87904
Xenopus	407952, 398459			490882
Zebrafish	57934, 57935	ENSDARG00000037746, ENSDARG00000037870	ZDB-GENE-000329-1, ZDB-GENE-000329-3	ZFIN:ZDB-GENE-000329-1, ZFIN:ZDB-GENE-000329-3

Gene Ontology

Molecular Function	ATP binding, kinesin binding, nitric-oxide synthase binding, Tat protein binding
Biological Process
Cellular Component	cytoplasm, cytoskeleton, extracellular vesicular exosome, MLL5-L complex, more...

Links to other databases

Entrez Gene	396526
Ensembl Gene	ENSGALG00000009621
KEGG	gga:396526

Entry 1

GEISHA Id	ACTBcyto.Ruzicka.1988	Data Source	Publication
Complete cDNA Template Probe	show GGAACAACNNGGCCGCCTCGCGCCGCCCGCCCCGGCTCTGACTGACCGCGTTACTCCCACAGCCAGCCATGGATGATGA TATTGCTGCGCTCGTTGTTGACAATGGCTCCGGTATGTGCAAGGCCGGTTTCGCCGGGGACGATGCCCCCCGTGCTGTG TTCCCATCTATCGTGGGTCGCCCCAGACATCAGGGTGTGATGGTTGGTATGGGCCAGAAAGACAGCTACGTTGGTGATG AAGCCCAGAGCAAAAGAGGTATCCTGACCCTGAAGTACCCCATTGAACACGGTATTGTCACCAACTGGGATGATATGGA GAAGATCTGGCACCACACTTTCTACAATGAGCTGAGAGTAGCCCCTGAGGAGCACCCTGTGCTGCTCACAGAGGCTCCC CTGAACCCCAAAGCCAACAGAGAGAAGATGACACAGATCATGTTTGAGACCTTCAACACCCCAGCCATGTATGTAGCCA TCCAGGCTGTGCTGTCCCTGTATGCCTCTGGTCGTACCACTGGTATTGTGATGGACTCTGGTGATGGTGTTACCCACAC TGTGCCCATCTATGAAGGCTACGCCCTCCCCCATGCCATCCTCCGTCTGGATCTGGCTGGCCGTGACCTGACGGACTAC CTCATGAAGATCCTGACAGAGAGAGGCTACAGCTTCACCACCACAGCCGAGAGAGAAATTGTGCGTGACATCAAGGAGA AGCTGTGCTACGTCGCACTGGATTTCGAGCAGGAGATGGCCACAGCTGCCTCTAGCTCTTCCCTGGAGAAGAGCTATGA ACTCCCTGATGGTCAGGTCATCACCATTGGCAATGAGAGGTTCAGGTGCCCCGAGGCCCTCTTCCAGCCATCTTTCTTG GGTATGGAGTCCTGTGGTATCCATGAAACTACCTTCAACTCCATCATGAAGTGTGATGTGGATATCCGTAAGGATCTGT ATGCCAACACAGTGCTGTCTGGTGGTACCACAATGTACCCTGGCATTGCTGACAGGATGCAGAAGGAGATCACAGCCCT GGCACCTAGCACAATGAAAATCAAGATCATTGCCCCACCTGAGCGCAAGTACTCTGTCTGGATTGGAGGCTCTATCCTG GCCTCCCTGTCCACCTTCCAGCAGATGTGGATCAGCAAGCAGGAGTACGATGAATCCGGACCCTCCATTGTCCACCGCA AATGCTTCTAAACCGGACTGTTACCAACACCCACACCCCTGTGATGAAACAAAACCCATAAATGCGCATAAAACAAGAC GAGATTGGCATGGCTTTATTTGTTTTTTCTTTTGGCGCTTGACTCAGGATTAAAAAACTGGAATGGTGAAGGTGTCAGC AGCAGTCTTAAAATGAAACATGTTGGAGCGAACGCCCCCAAAGTTCTACAATGCATCTGAGGACTTTGATTGTACATTT GTTTCTTTTTTAATAGTCATTCCAAATATTGTTATAATGCATTGTTACAGGAAGTTACTCGCCTCTGTGAAGGCAACAG CCCAGCTGGGAGGAGCCGGTACCAATTACTGGTGTTAGATGATAATTGCTTGTCTGTAAATTATGTAACCCAACAAGTG TCTTTTTGTATCTTCCGCCTTAAAAACAAAACACACTTGATCCTTTTTGGTTTGTCAAGCAAGCGGGCTGTGTTCCCCA GTGATAGATGTGAATGAAGGCTTTACAGTCCCCCACAGTCTAGGAGTAAAGTGCCAGTATGTGGGGGAGGGAGGGGG
Citation	Ruzicka DL, Schwartz RJ. Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation. J Cell Biol. 1988 Dec;107(6 Pt 2):2575-86.
Copyright	© The Rockefeller University Press,
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_205518.1 ).

Stage

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4-6

stage 5

Ubiquitous

7-12

stage 10

stage 13

Ubiquitous

Entry 2

GEISHA Id	ACTB.Lin.2012B	Data Source	Publication
Complete cDNA Template Probe	show CGCCCCGGCTCTGACTGACCGCGTTACTCCCACAGCCAGCCATGGATGATGATATTGCTGCGCTCGTTGTTGACAATGG CTCCGGTATGTGCAAGGCCGGTTTCGCCGGGGACGATGCCCCCCGTGCTGTGTTCCCATCTATCGTGGGTCGCCCCAGA CATCAGGGTGTGATGGTTGGTATGGGCCAGAAAGACAGCTACGTTGGTGATGAAGCCCAGAGCAAAAGAGGTATCCTGA CCCTGAAGTACCCCATTGAACACGGTATTGTCACCAACTGGGATGATATGGAGAAGATCTGGCACCACACTTTCTACAA TGAGCTGAGAGTAGCCCCTGAGGAGCACCCTGTGCTGCTCACAGAGGCTCCCCTGAACCCCAAAGCCAACAGAGAGAAG ATGACACAGATCATGTTTGAGACCTTCAACACCCCAGCCATGTATGTAGCCATCCAGGCTGTGCTGTCCCTGTATGCCT CTGGTCGTACCACTGGTATTGTGATGGACTCTGGTGATGGTGTTACCCACACTGTGCCCATCTATGAAGGCTACGCCCT CCCCCATGCCATCCTCCGTCTGGATCTGGCTGGCCGTGACCTGACGGACTACCTCATGAAGATCCTGACAGAGAGAGGC TACAGCTTCACCACCACAGCCGAGAGAGAAATTGTGCGTGACATCAAGGAGAAGCTGTGCTACGTCGCACTGGATTTCG AGCAGGAGATGGCCACAGCTGCCTCTAGCTCTTCCCTGGAGAAGAGCTATGAACTCCCTGATGGTCAGGTCATCACCAT TGGCAATGAGAGGTTCAGGTGCCCCGAGG
Citation	Lin J, Redies C. Histological evidence: housekeeping genes beta-actin and GAPDH are of limited value for normalization of gene expression. Dev Genes Evol. 2012
Copyright	© Springer-Verlag Berlin Heidelberg 2012
Comments	The cDNA template used to generate the probe was obtained by PCR as described in Lin et al. ACTB (NCBI accession number: NM_205518); the forward primer for ACTB was 5'-CGCCCCGGCTCTGACTGACC-3' and the reverse primer was 5'-CCTCGGGGCACCTGAACCTCTC-3' (expected length 819 bp).