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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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ADAM12
ADAM metallopeptidase domain 12

Gene

Official Symbol	ADAM12
Official Full Name	ADAM metallopeptidase domain 12
CGNC ID	9663
also known as	disintegrin and metalloproteinase domain-containing protein 12\|ADAM metallopeptidase domain 12 (meltrin alpha)\|ADAM12 short isoform\|disintegrin and metalloprotease 12
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001142850
Polypeptide	NP_001136322
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.31031

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	3772109			FBgn0265140
Human	8038	ENSG00000148848		MIM:602714
Mouse	11489	ENSMUSG00000054555	All phenotypic alleles (1):Targeted, knock-out(1)	MGI:105378
Xenopus	677729			982138
Zebrafish	563275	ENSDARG00000079068	ZDB-GENE-070809-1	ZFIN:ZDB-GENE-070809-1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	425843
Ensembl Gene	ENSGALG00000012740
KEGG	gga:425843

Entry 1

GEISHA Id	ADAM12.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	GCAAAGCATCTACTGACAAAGGGG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTTGGTTCCTGACAGCACGAGAC	cDNA Template Length	805
Forward cDNA Template Probe	show GGCAGGTCATCCCCCAGATACACGTGGGTGCCACGACACAGGATCTTCCCACCGTTCCTGAAGCGGGATATTGGTTTCT ATGGAAACAGCATTGGTACCAATTACAGGTCGATTGGCTCCTCCTTGACACTGAATTTTTCCACATTTAGCATCTCTGG GCTCACACTTGGCGAAGGAGCTCTTGGAGTCTTTGCCACAGTTGCCGTATGGATCACCTGCAGAGTTGACTCTCTCAAA GCAGATCCCAGGAGCAGGTTTGGCACCCTGGCCCCAGAGGGTGATGCACTGCTGCTCGTGGGTCTGGCAGATGCCGTTG TAGCAGTAGCCGTCCACCCCGTGGCACGCGTGCCCGTCGTGCAGGTACACATTAGCTGGGCAGTGAGGGCTGGCTCCAG TGCAAAACTCTGGCAGATCACAGGAATTGCTCGACTCTCTGCAAGAAATCCCCGCTGGTTTTAACTTGCAGTCTTCGCA GCAAAGTCCGTGTGCACACACTGCTCCTGGCCTCAAAGTGCAGGTAGTTGCGTTGCAGCACCGGTTTGTACATTCATCG GGCTCCCCACAGTCGCACTCCTCTCCATCTTCCACGTAGCCNTTCCCACACTTCTGTCCACCAAAGGACTCCTTGACTT CAGGCAAGTTAAACAGACACATTCCCACTCCTTTCTCCAGGCTGTTTTCCAGGTCCTTTCTACTGCAGCTGCTGAACAC CATGGGAAATGGATAGCCTGTANAAGGATTCATGATGCAGCCCCCTTTGTCAGTA

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 5

Early Mesoderm
Epiblast
Primitive Streak

7-12

stage 8

stage 9

stage 12

Amnion
Anterior Intestinal Portal
Anterior Neuropore
Heart Tube
Lateral Plate Mesoderm
Neural Crest
Neural Plate/Tube
Sinus Venosus
extraembryonic endoderm

13-18

stage 17

Amnion
Aorta
Head Mesenchyme
Heart
Liver
Midbrain
Notochord
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm

19-24

stage 20

stage 24

Aorta
Atria
Eye
Foregut
Heart
Liver
Lung
Mesonephros
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Sinus Venosus
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Ventricles

dorsal mesentery, genital ridge

25-26

stage 25

stage 26

Atria
Cardinal Veins
Forebrain
Foregut
Gizzard
Head Mesenchyme
Heart
Hindbrain
Hindgut
Leg Mesenchyme
Lung
Mesonephros
Midbrain
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Ventricles
Wing Mesenchyme

Entry 2

GEISHA Id	ADAM12.Lewis.2004	Data Source	Publication
Complete cDNA Template Probe	show TTCGGCACGAGATGAAAGTTTGTCTCCCTCAGTCCGGGTTAAGATGTCAAAGCGTCTCCGTGCGGAGCGGCAGCGCTCC CCGGCTCCGCGTCCCTCCGTGCTGCTGCTGATCCTCAGCGCAATGCTCCTCGCATCACCCCGAGCGGGAGGTCAGAATG TGGACAACAAGTTGGAGTCCTTGAGACAGCAGATGCTGAAGGACCAGTCAAAAGATTATGAGATAACAGTTCCCTTCCT TTTGAATGGAGAACAGTGGAGACCAGCAAACAGCATTTATTCCAAGGACCACCCATCCCTGCTGCAGTTGGTGGTACAA GTTGAAGGGGAACGTCTGGTCATCCACCTGGAGAGAAACGAGGGCCTGTTAGCCAGCAGCTTCACAGAAACACATTATT TGAAGGATGGGACTGATGTGGTTCTCTCACGCAATTACACGGGTCACTGCTATTACCACGGCAATGTACGAGGGTACCC CAGTTCATCAGTCAGTCTCAATACCTGCTCGGGACTCAAGGGAATTATTATGCTTGGAAACAAAAACTACGTTCTGGAG CCGATAGAAAGGGCTACAAGTGAACACAAGATCTACCGAGCGGAGAACTTGGAAATAATTCCAGGGTCTTGTGGCCACC AGCTGGACATCTCTGCCATGAGGGCTGCTGATGCATCACACCGCTCTCAAGCTGGCAGGTACAAGAGGGAGACTCTGAA GACGACAAAGTATGTGGAGCTTGTTATTGTGGCGGATAATCGTGAGTTTCAGAGGCAAGGCAAGGATGTGGAAAAAATT AAGCAGAGGCTGATAGAAATTGCAAACTATGTCGATAAGTTCTATAGGCCGCTAAACATTCGAGTAGCCCTGGTGGGAG TGGAGGTGTGGAACGACATGGATAAGTGCTCTATTTCTCAAGACCCTTTCACCAGCCTCCATGAGTCTCTGGACTGGAG AAAGCTAAAACTACTACCTCGCAAACCCCATGACAATGCACAGCTAATAAGCGGGGTGTACTTCCAGGGGACAACCATT GGCATGGCTCCCATCATGAGCATGTGCACTGCAGAGCAGTCTGGAGGGGTCGTCATGGATCATTCAGAAAACCCTCTTG GTGCAGCAGTCACCCTGGCTCATGAGCTGGGCCACAACTTTGGGATGAATCACGATACGTTGGAGAGGGGCTGCAACTG CAAAGCATCTACTGACAAAGGGGGTTGCATCATGAATCCTTCTACGGGCTATCCGTTTCCCATGGTGTTCAGCAGCTGC AGTAGAAAGGACCTGGAAAACAGCCTGGAGAAAGGAGTGGGGATGTGTCTGTTTAACTTGCCTGAAGTCAAGGAGTCCT TTGGTGGACAGAAGTGTCGGGAATTGGCTACCGTGGAAGATGGAGAGGAGTGCGACTGGGGGAGCCCTGATGAATGTAC AAACCGGTGCTGCAATGCAACTACCTGCACTTTGAGGCCAGGAGCAGTGTGTGCACATGGACTGTGCTGCGAAGACTGC AAGTTAAAACCAGCGGGGATTTCTTGTAGAGAGTCGAGCAATTCCTGCGACCTGCCAGAGTTCTGCACCGGAGCCAGCC CTCACTGCCCAGCTAATGTCTACCTGCACGACGGGCACGCGTGCCATGGAGTGGATGGCTACTGCTACAACGGCATCTG CCAGACCCACGAGCAGCAGTGCATCACCCTCTGGGGCCAGGGTGCCAAACCTGCTCCTGGGATCTGCTTTGAGAGAGTC AATTCTGCAGGTGATCCATATGGCAACTGTGGCAAAGACTCCAAGAGCAGCTTTGCCAAGTGTGAGCCCAGAGATGCTA AATGTGGCAAAATTCAGTGTCAAGGAGGTGCCAATCGACCCGTAATTGGTACCAATGCTGTTTCCATTGAAACCAATAT CCCTCTTCAGGAAGGTGGCAAGATCCTGTGTCGTGGCACCCACGTGTACCTGGGGGATGACATGCCTGACCCTGGTCTC GTGCTGTCAGGAACCAAGTGTGAGGATGGAAAAATTTGCCTTAATCGCCGGTGCCAGAATACAAGTGTTTTTGGTGTGC ATAAGTGTGCAACAAAGTGCCATGGACGTGGAGTTTGCAACAACAAAAAGAACTGTCACTGTGAGGCTGACTGGGCTCC CCCATACTGCGACAAGCCGGGCTTTGGTGGCAGCGTGGACAGTGGGCCCATCAGGCAAGCAGATAATAAGAGTTTAACT GTAGGAGTGTTGATCACCATTCTGTGCCTTACCTTTGCTGGGTCAGTCATGTATCTGAAAAGGAAGACTCTCATGAGAC TGCTGTTTACAAGTAAGAAGACGACAATAGAGAAATTAAGGTCTGTGAGCCCAGCGAGATCTTCTAGATCATCTAAGCC CAATCACATTCGTACAGCATCTCTCAGTAAAAACCTCATCATGAAGCCACAAAATACAAACATGCAAAAAAGAGACGGC CCAAGGCGCCCGCTGCCCTATCAGATTGTTGACATCAGTGACCCAGTGAAGACCGACCATGTGCCACAGCCAAAGACCC CACATCGTGTCCTGCCGCCCCTTCCCCAGCCACCCTGCCACCAAGCTGGGCCTGAAAGCGCTTCCTGCAACCCCACGCT CAGGCTGTCCCAGGAAAACCACAAGCCAAGCCCTCCTCGGAAGCCTCTACCAGCAGATCCCCTGAACAAAGCTCGTTAT AACACGCATGTGCTCTCCAGGCTTGGACTCACAAAAGCGCCGCCTCACGTTGCTCCTGCAAGACCAGCTCCCAAGCATC CACCGCCGGTACCCAGGTCCAGCAATGCAGCTGCTGATGTGAAATGATGAGGAAATCGGACAGCTTTATTATAAAAAGT GAAGACAGAAGTTTGCACTATCTTTCAACTCCAGCTGGAGTTCATTTTTATGACAATACTTAGACTTTTTAATGTTTAA AACAGCATTATTTTTTAAGAGTTCTGAGCTACTGCCTTTTGGTGCTGTGCTGTGCTATGGTGCTCTGTATACTTGCTCA GGTACTTGTAAATTATTAATTTATGTTGAATATTTATTACAGTGCAGTGCACTGTAGTAGATATTTTTACCATAGCTGA GTTTTCCTAAAAAGGAAGCCTTTTTTTGTAATATTTCAGTGAACTTGAATAATTCTGCTCTATCGGTCCTATAGAGGGT GTTTAGTTTCCATCTATAAGGAATGCTGATACTCATGGATAAATCACACACGTGGAAAATTCAATCTCAGTAGGTCATA GCAAACTCTTGACTACACGTGTCAGGGGAAAGCAGCTGGAACATGGTGAAACGCCTGATATCTGCACCCAGCGGTACTC ACCAAAGTGTCTCTCAGTGTTAGCAGTTGTACTGTAATCTCATTTTTCATGTTACTGTTTGAAATCGTTGAGAAATCTG TGCTGAAAGAGGCGTCTGTCTTTTTGGACAGTTCTCTTCATGAAGAAGTACTGTACATATCTCTCATAACTGTGTTTTT GACCTCATTTTCCTCAGACACAACATGACTAGCACATACCGATGCAGATATCAGGCCTTCCAGTGTCATTACCTTTTTG ATTACTTAATTCAACCTATGCCATGTAAGGTAGTACCATCTCACTATGTTGCATACCTGTACCACTTAGACTGAAGCCA CACTACATGTAAGGGGTGGGGGGATGCCAAGCATGACAAAGAATTAACGTGTTTCTTTAAAACTCAACTATTATACTTA GTTTCTTTTGCCTCATCGCTCTGCTTATCAACTGATTTTTCCGATCTACTACTGTTATGTATTTAACTTCTTAAAATGT TGCTCTGGGTTTCTTAACTTTGAAATCAAAATACGTATTTTAGAACATTGCCTTTGGTTTGCTTAAGACATGGAGACAG AATTTCATCTCTTTGGTACCTTTCTCAGTAGCACTGCTGAACACCGTTGTTTCACATATGCTGTAATAGAAACAACTTA CAAATACCAGTTGGAACAGAGGAGGAAGAAGGTCTTACCTTACACTTACTAGTTCACTCATTGCCTGGCAGTTGTTTTG TTTTTTTAAGCAAAAATAAAAGCATTAATAGAAACTTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Citation	Lewis SL, Farlie PG, Newgreen DF. Isolation and embryonic expression of avian ADAM 12 and ADAM 19. Gene Expr Patterns. 2004 Nov;5(1):75-9.
Copyright	Reprinted with permission from Elsevier. Copyright © 2004 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AF456466).The sequence is from Quail.

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Head Mesenchyme
Limb Buds
Neural Crest
Tail
Wing Mesenchyme

Quail

25-26

stage 26

Aorta
Neural Plate/Tube
Spinal Ganglia and Nerves
Splanchnic Mesoderm
Trunk Mesenchyme

Dorsal Root Ganglia
Mixed Nerve
Pericardial Cavity
Quail
Trigeminal Ganglia
Ventral Motor Roots
Visceral Mesenchyme

Entry 3

GEISHA Id	ADAM12.Yan.2011	Data Source	Publication
Complete cDNA Template Probe	show ATGTCAAAGCGTCTCCTTGCGGAGCGGCAGCGCTCCCCCGCTCCGCGCCCCTCCGTGCTGCTGCTGAGCCTCAGCGCGC TGCTCCTAGCATCACCCCGAGCGCGAGGTCAGAATGTGGACAGCAAGTTGGAGTCCTTGAGACAGCAGATGCTGAAGGA CCAGTCAAAAGATTATGAGATAACAGTTCCCCTCCTTTTGAATGGAGAACAGTGGAGACCAGCAAACAGCATTTATTCC AAGAACCACCCGTCCCTGCTGCAGTTGGTGGTACAAGCTGAAGGGGAACGTCTGGTCATCCACCTGGAGAGGAACGAGG GCCTGCTAGCCAGCAGCTTCACAGAAACACATTATTTGAAGGATGGTACTGATGTGGTTCTCTCACGCAATTACACGGG TCACTGCTATTACCACGGCAATGTACGAGGGTACCCCAGTTCGTCAGTCAGTCTCAGTACCTGCTCTGGACTCAGGGGA ATTATTGTGTTTGAAAACAAAAGCTACATTCTGGAGCCGTTAGAAGGTGCTACAAGTGAACACAAGATCTACCGAGCAG AGAACTTGGAAATAATTCCAGGGTCGTGTGGCCACCAGCTGGACATCTCTGCCACGAGGGCTGCTGACCCATCGCACCG CTCTCAAGGCGGCAGGTACAAGAGGGAGACTCTGAAGACGACAAAGTATGTGGAGCTTGTTATTGTGGCGGATAATCGT GAGTTTCAGAGACAAGGCAAGGATGTGGAAAAAATTAAGCAGAGGCTGATAGAAATTGCAAACTATGTCGATAAGTTCT ATAGGCCGCTGAATATTCGAGTAGCCCTGGTTGGAGTGGAAGTGTGGAACGACATGGATAAGTGCTCTATCTCTCAAGA CCCTTTCACCAGCCTCCATGAGTTTCTGGACTGGAGAAAGCTAAAATTACTACCTCGTAAACCCCATGACAACGCACAG CTAATAAGCGGGGTGTACTTCCAGGGGACAACCATTGGCATGGCGCCCATCATGAGCATGTGCACTGCAGAGCAGTCTG GAGGGGTCGTCATGGATCATTCAGAAAACCCTCTTGGTGCAGCCGTCACCCTGGCTCATGAGCTGGGCCACAACTTCGG GATGAATCATGATACGTTGGAGAGGGGCTGCAACTGCAAAGCATCTACTGACAAAGGGGGCTGCATCATGAATCCTTCT ACAGGCTATCCATTTCCCATGGTGTTCAGCAGCTGCAGTAGAAAGGACCTGGAAAACAGCCTGGAGAAAGGAGTGGGAA TGTGTCTGTTTAACTTGCCTGAAGTCAAGGAGTCCTTTGGTGGACAGAAGTGTGGGAACGGCTACGTGGAAGATGGAGA GGAGTGCGACTGTGGGGAGCCCGATGAATGTACAAACCGGTGCTGCAACGCAACTACCTGCACTTTGAGGCCAGGAGCA GTGTGTGCACACGGACTTTGCTGCGAAGACTGCAAGTTAAAACCAGCGGGGATTTCTTGCAGAGAGTCGAGCAATTCCT GTGATCTGCCAGAGTTTTGCACTGGAGCCAGCCCTCACTGCCCAGCTAATGTGTACCTGCACGACGGGCACGCGTGCCA CGGGGTGGACGGCTACTGCTACAACGGCATCTGCCAGACCCACGAGCAGCAGTGCATCACCCTCTGGGGCCAGGGTGCC AAACCTGCTCCTGGGATCTGCTTTGAGAGAGTCAACTCTGCAGGTGATCCATACGGCAACTGTGGCAAAGACTCCAAAA GCTCCTTCGCCAAGTGTGAGCCCAGAGATGCTAAATGTGGAAAAATTCAGTGTCAAGGAGGAGCCAATCGACCTGTAAT TGGTACCAATGCTGTTTCCATAGAAACCAATATCCCACTTCAGGAAGGTGGGAAGATCCTGTGTCGTGGCACCCACGTG TATCTGGGGGATGACATGCCTGACCCTGGTCTCGTGCTGTCAGGAACCAAGTGTGAAGATGGAAAGATTTGCCTTAATC GCCGGTGCCAGAATACAAGTGTTTTTGGTGTGCATAAGTGTGCAACAAAGTGCCATGGACGTGGAGTTTGCAACAACAA AAAGAACTGTCACTGTGAGGCTGACTGGGCCCCCCCATACTGTGACAAGCCGGGCTTTGGTGGCAGCGTGGACAGCGGG CCCATCAGGCAAGCAGATAATAAGAGTTTAACCGTAGGAGTGTTGATCACCATTCTGTGCCTTACCTTTGCTGGGTCAG TCATGTATCTAAAAAGGAAGACTCTCATGAGATTGCTGTTTACAAGTAAGAAGACGACGATAGAGAAATTAAGGTCTGT GAGCCCAGCGAGATCTTCTAGATCATCTAAGCTCAATCACGTTCGTACCACATCTCTCAGTAAAAATCTCATGATGAAG CCACAAAATGCAAACGTGCAAAAAAGAGACGGCCCGAGGCGCCCGCTGCCCTATCAGATCGTTGACATCAGTGACCCGG TGAAGACACACCATGTGCCACAGCTGAAGACCCCACAGCGTGTCCTGCCACCCCTTCCTCAGCCGCCCTGCCACCAAGC TGGCCCTGAAAGGCCCCTTCCTGCTAACCCCACTCTCAGGCTCCCCCAGGAAAACCACAAGCCAAGCCCTCCTCGGAAG CCTCTACCAGCAGATCCCCTGAACAAAACTCGTTATAACAGTGCGTGCACCCCAGGGCTTGGACACACAAAAGCGCTGC CTCACATTGCTCCTGCAAGACCTGCTCCCAAGCATCCACCACCAGTACCCAGGTCCAGCAATGCTACTGCTGATGTGAA ATGA
Citation	Yan X, Lin J, Rolfs A, Luo J. Differential expression of the ADAMs in developing chicken retina. Dev Growth Differ. 2011 Jun;53(5):726-39.
Copyright	copyright 2011 The Authors
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_001142850).

Stage

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Location (click to highlight)

Comments (click to highlight)

25-30

stage 27

Retina

31-44

stage 31

stage 35

stage 38

stage 40

stage 42

stage 44

Retina
Unlabeled

Entry 4

GEISHA Id	ADAM12.Lin.2010	Data Source	Publication
Complete cDNA Template Probe	show ATGTCAAAGCGTCTCCTTGCGGAGCGGCAGCGCTCCCCCGCTCCGCGCCCCTCCGTGCTGCTGCTGAGCCTCAGCGCGC TGCTCCTAGCATCACCCCGAGCGCGAGGTCAGAATGTGGACAGCAAGTTGGAGTCCTTGAGACAGCAGATGCTGAAGGA CCAGTCAAAAGATTATGAGATAACAGTTCCCCTCCTTTTGAATGGAGAACAGTGGAGACCAGCAAACAGCATTTATTCC AAGAACCACCCGTCCCTGCTGCAGTTGGTGGTACAAGCTGAAGGGGAACGTCTGGTCATCCACCTGGAGAGGAACGAGG GCCTGCTAGCCAGCAGCTTCACAGAAACACATTATTTGAAGGATGGTACTGATGTGGTTCTCTCACGCAATTACACGGG TCACTGCTATTACCACGGCAATGTACGAGGGTACCCCAGTTCGTCAGTCAGTCTCAGTACCTGCTCTGGACTCAGGGGA ATTATTGTGTTTGAAAACAAAAGCTACATTCTGGAGCCGTTAGAAGGTGCTACAAGTGAACACAAGATCTACCGAGCAG AGAACTTGGAAATAATTCCAGGGTCGTGTGGCCACCAGCTGGACATCTCTGCCACGAGGGCTGCTGACCCATCGCACCG CTCTCAAGGCGGCAGGTACAAGAGGGAGACTCTGAAGACGACAAAGTATGTGGAGCTTGTTATTGTGGCGGATAATCGT GAGTTTCAGAGACAAGGCAAGGATGTGGAAAAAATTAAGCAGAGGCTGATAGAAATTGCAAACTATGTCGATAAGTTCT ATAGGCCGCTGAATATTCGAGTAGCCCTGGTTGGAGTGGAAGTGTGGAACGACATGGATAAGTGCTCTATCTCTCAAGA CCCTTTCACCAGCCTCCATGAGTTTCTGGACTGGAGAAAGCTAAAATTACTACCTCGTAAACCCCATGACAACGCACAG CTAATAAGCGGGGTGTACTTCCAGGGGACAACCATTGGCATGGCGCCCATCATGAGCATGTGCACTGCAGAGCAGTCTG GAGGGGTCGTCATGGATCATTCAGAAAACCCTCTTGGTGCAGCCGTCACCCTGGCTCATGAGCTGGGCCACAACTTCGG GATGAATCATGATACGTTGGAGAGGGGCTGCAACTGCAAAGCATCTACTGACAAAGGGGGCTGCATCATGAATCCTTCT ACAGGCTATCCATTTCCCATGGTGTTCAGCAGCTGCAGTAGAAAGGACCTGGAAAACAGCCTGGAGAAAGGAGTGGGAA TGTGTCTGTTTAACTTGCCTGAAGTCAAGGAGTCCTTTGGTGGACAGAAGTGTGGGAACGGCTACGTGGAAGATGGAGA GGAGTGCGACTGTGGGGAGCCCGATGAATGTACAAACCGGTGCTGCAACGCAACTACCTGCACTTTGAGGCCAGGAGCA GTGTGTGCACACGGACTTTGCTGCGAAGACTGCAAGTTAAAACCAGCGGGGATTTCTTGCAGAGAGTCGAGCAATTCCT GTGATCTGCCAGAGTTTTGCACTGGAGCCAGCCCTCACTGCCCAGCTAATGTGTACCTGCACGACGGGCACGCGTGCCA CGGGGTGGACGGCTACTGCTACAACGGCATCTGCCAGACCCACGAGCAGCAGTGCATCACCCTCTGGGGCCAGGGTGCC AAACCTGCTCCTGGGATCTGCTTTGAGAGAGTCAACTCTGCAGGTGATCCATACGGCAACTGTGGCAAAGACTCCAAAA GCTCCTTCGCCAAGTGTGAGCCCAGAGATGCTAAATGTGGAAAAATTCAGTGTCAAGGAGGAGCCAATCGACCTGTAAT TGGTACCAATGCTGTTTCCATAGAAACCAATATCCCACTTCAGGAAGGTGGGAAGATCCTGTGTCGTGGCACCCACGTG TATCTGGGGGATGACATGCCTGACCCTGGTCTCGTGCTGTCAGGAACCAAGTGTGAAGATGGAAAGATTTGCCTTAATC GCCGGTGCCAGAATACAAGTGTTTTTGGTGTGCATAAGTGTGCAACAAAGTGCCATGGACGTGGAGTTTGCAACAACAA AAAGAACTGTCACTGTGAGGCTGACTGGGCCCCCCCATACTGTGACAAGCCGGGCTTTGGTGGCAGCGTGGACAGCGGG CCCATCAGGCAAGCAGATAATAAGAGTTTAACCGTAGGAGTGTTGATCACCATTCTGTGCCTTACCTTTGCTGGGTCAG TCATGTATCTAAAAAGGAAGACTCTCATGAGATTGCTGTTTACAAGTAAGAAGACGACGATAGAGAAATTAAGGTCTGT GAGCCCAGCGAGATCTTCTAGATCATCTAAGCTCAATCACGTTCGTACCACATCTCTCAGTAAAAATCTCATGATGAAG CCACAAAATGCAAACGTGCAAAAAAGAGACGGCCCGAGGCGCCCGCTGCCCTATCAGATCGTTGACATCAGTGACCCGG TGAAGACACACCATGTGCCACAGCTGAAGACCCCACAGCGTGTCCTGCCACCCCTTCCTCAGCCGCCCTGCCACCAAGC TGGCCCTGAAAGGCCCCTTCCTGCTAACCCCACTCTCAGGCTCCCCCAGGAAAACCACAAGCCAAGCCCTCCTCGGAAG CCTCTACCAGCAGATCCCCTGAACAAAACTCGTTATAACAGTGCGTGCACCCCAGGGCTTGGACACACAAAAGCGCTGC CTCACATTGCTCCTGCAAGACCTGCTCCCAAGCATCCACCACCAGTACCCAGGTCCAGCAATGCTACTGCTGATGTGAA ATGA
Citation	Lin J, Luo J, Redies C. Molecular characterization and expression analysis of ADAM12 during chicken embryonic development. Dev Growth Differ. 2010 Dec;52(9):757-69.
Copyright	© 2010 The Authors. Journal compilation © 2010 Japanese Society of Developmental Biologists.
Comments	The cDNA template used to generate the probe was obtained by PCR as described in the paper. AM12-ORF-R: 5′-ATGTCAAA-GCGTCTCCTTGCG-3′ and AM12-ORF-L: 5′-ATCAT-TTCACATCAGCAGTAGC-3′. As the second primer could not be identified, the sequence shown is NM_001142850.1.

Stage

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Location (click to highlight)

Comments (click to highlight)

7-12

stage 10

stage 12

Diencephalon
Eye
Head Mesenchyme
Heart Tube
Tail

13-18

stage 17

Eye
Heart
Splanchnic Mesoderm
Trunk Mesenchyme

19-24

stage 19

stage 24

Allantois
Aorta
Cranial Nerve
Cranial PNS
Eye
Head Mesenchyme
Heart
Spinal Ganglia and Nerves
Tail

25-30

stage 27

stage 29

Aorta
Cranial Nerve
Esophagus
Eye
Heart
Leg
Lung
Mesonephros
Myotome
Spinal Cord
Spinal Ganglia and Nerves
Splanchnic Mesoderm
Ventricles

aortic arches
roof plate

31-38

stage 34

stage 35

stage 36

stage 37

stage 38

Dermis
Ectoderm
Feathers/Scutae
Gizzard
Intermediate Mesoderm
Leg
Leg Bones
Leg Muscles
Lung
Mesonephros
Myotome
Sclerotome
Somatic Mesoderm
Splanchnic Mesoderm
Surface Ectoderm
Wing

cartilage
cells around the oviduct
fe, femur
skeletal muscle
skeletal muscle cells

Entry 5

GEISHA Id	ADAM12.Lin.2010B	Data Source	Publication
Complete cDNA Template Probe	show ATGTCAAAGCGTCTCCTTGCGGAGCGGCAGCGCTCCCCCGCTCCGCGCCCCTCCGTGCTGCTGCTGAGCCTCAGCGCGC TGCTCCTAGCATCACCCCGAGCGCGAGGTCAGAATGTGGACAGCAAGTTGGAGTCCTTGAGACAGCAGATGCTGAAGGA CCAGTCAAAAGATTATGAGATAACAGTTCCCCTCCTTTTGAATGGAGAACAGTGGAGACCAGCAAACAGCATTTATTCC AAGAACCACCCGTCCCTGCTGCAGTTGGTGGTACAAGCTGAAGGGGAACGTCTGGTCATCCACCTGGAGAGGAACGAGG GCCTGCTAGCCAGCAGCTTCACAGAAACACATTATTTGAAGGATGGTACTGATGTGGTTCTCTCACGCAATTACACGGG TCACTGCTATTACCACGGCAATGTACGAGGGTACCCCAGTTCGTCAGTCAGTCTCAGTACCTGCTCTGGACTCAGGGGA ATTATTGTGTTTGAAAACAAAAGCTACATTCTGGAGCCGTTAGAAGGTGCTACAAGTGAACACAAGATCTACCGAGCAG AGAACTTGGAAATAATTCCAGGGTCGTGTGGCCACCAGCTGGACATCTCTGCCACGAGGGCTGCTGACCCATCGCACCG CTCTCAAGGCGGCAGGTACAAGAGGGAGACTCTGAAGACGACAAAGTATGTGGAGCTTGTTATTGTGGCGGATAATCGT GAGTTTCAGAGACAAGGCAAGGATGTGGAAAAAATTAAGCAGAGGCTGATAGAAATTGCAAACTATGTCGATAAGTTCT ATAGGCCGCTGAATATTCGAGTAGCCCTGGTTGGAGTGGAAGTGTGGAACGACATGGATAAGTGCTCTATCTCTCAAGA CCCTTTCACCAGCCTCCATGAGTTTCTGGACTGGAGAAAGCTAAAATTACTACCTCGTAAACCCCATGACAACGCACAG CTAATAAGCGGGGTGTACTTCCAGGGGACAACCATTGGCATGGCGCCCATCATGAGCATGTGCACTGCAGAGCAGTCTG GAGGGGTCGTCATGGATCATTCAGAAAACCCTCTTGGTGCAGCCGTCACCCTGGCTCATGAGCTGGGCCACAACTTCGG GATGAATCATGATACGTTGGAGAGGGGCTGCAACTGCAAAGCATCTACTGACAAAGGGGGCTGCATCATGAATCCTTCT ACAGGCTATCCATTTCCCATGGTGTTCAGCAGCTGCAGTAGAAAGGACCTGGAAAACAGCCTGGAGAAAGGAGTGGGAA TGTGTCTGTTTAACTTGCCTGAAGTCAAGGAGTCCTTTGGTGGACAGAAGTGTGGGAACGGCTACGTGGAAGATGGAGA GGAGTGCGACTGTGGGGAGCCCGATGAATGTACAAACCGGTGCTGCAACGCAACTACCTGCACTTTGAGGCCAGGAGCA GTGTGTGCACACGGACTTTGCTGCGAAGACTGCAAGTTAAAACCAGCGGGGATTTCTTGCAGAGAGTCGAGCAATTCCT GTGATCTGCCAGAGTTTTGCACTGGAGCCAGCCCTCACTGCCCAGCTAATGTGTACCTGCACGACGGGCACGCGTGCCA CGGGGTGGACGGCTACTGCTACAACGGCATCTGCCAGACCCACGAGCAGCAGTGCATCACCCTCTGGGGCCAGGGTGCC AAACCTGCTCCTGGGATCTGCTTTGAGAGAGTCAACTCTGCAGGTGATCCATACGGCAACTGTGGCAAAGACTCCAAAA GCTCCTTCGCCAAGTGTGAGCCCAGAGATGCTAAATGTGGAAAAATTCAGTGTCAAGGAGGAGCCAATCGACCTGTAAT TGGTACCAATGCTGTTTCCATAGAAACCAATATCCCACTTCAGGAAGGTGGGAAGATCCTGTGTCGTGGCACCCACGTG TATCTGGGGGATGACATGCCTGACCCTGGTCTCGTGCTGTCAGGAACCAAGTGTGAAGATGGAAAGATTTGCCTTAATC GCCGGTGCCAGAATACAAGTGTTTTTGGTGTGCATAAGTGTGCAACAAAGTGCCATGGACGTGGAGTTTGCAACAACAA AAAGAACTGTCACTGTGAGGCTGACTGGGCCCCCCCATACTGTGACAAGCCGGGCTTTGGTGGCAGCGTGGACAGCGGG CCCATCAGGCAAGCAGATAATAAGAGTTTAACCGTAGGAGTGTTGATCACCATTCTGTGCCTTACCTTTGCTGGGTCAG TCATGTATCTAAAAAGGAAGACTCTCATGAGATTGCTGTTTACAAGTAAGAAGACGACGATAGAGAAATTAAGGTCTGT GAGCCCAGCGAGATCTTCTAGATCATCTAAGCTCAATCACGTTCGTACCACATCTCTCAGTAAAAATCTCATGATGAAG CCACAAAATGCAAACGTGCAAAAAAGAGACGGCCCGAGGCGCCCGCTGCCCTATCAGATCGTTGACATCAGTGACCCGG TGAAGACACACCATGTGCCACAGCTGAAGACCCCACAGCGTGTCCTGCCACCCCTTCCTCAGCCGCCCTGCCACCAAGC TGGCCCTGAAAGGCCCCTTCCTGCTAACCCCACTCTCAGGCTCCCCCAGGAAAACCACAAGCCAAGCCCTCCTCGGAAG CCTCTACCAGCAGATCCCCTGAACAAAACTCGTTATAACAGTGCGTGCACCCCAGGGCTTGGACACACAAAAGCGCTGC CTCACATTGCTCCTGCAAGACCTGCTCCCAAGCATCCACCACCAGTACCCAGGTCCAGCAATGCTACTGCTGATGTGAA ATGA
Citation	Lin J, Yan X, Markus A, Redies C, Rolfs A, Luo J.Dev Expression of seven members of the ADAM family in developing chicken spinal cord. Dyn. 2010 Apr;239(4):1246-54.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_001142850).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 20

stage 24

Dermomyotome
Spinal Cord
Spinal Ganglia and Nerves
Surface Ectoderm

de, epidermis
vr, ventral root

25-30

stage 29

Dermomyotome
Myotome
Sclerotome
Spinal Cord
Spinal Ganglia and Nerves

me, meninges
rp, roof plate

31-37

stage 34

stage 36

stage 37

Sclerotome
Spinal Cord
Unlabeled
Vertebrae

me, meninges
rp, roof plate
vr, ventral root

Entry 6

GEISHA Id	ADAM12.Alev.2010	Data Source	Publication
Complete cDNA Template Probe	show TCTCTCACGCAATTACACGGGTCACTGCTATTACCACGGCAATGTACGAGGGTACCCCAGTTCGTCAGTCAGTCTCAGT ACCTGCTCTGGACTCAGGGGAATTATTGTGTTTGAAAACAAAAGCTACATTCTGGAGCCGTTAGAAGGTGCTACAAGTG AACACAAGATCTACCGAGCAGAGAACTTGGAAATAATTCCAGGGTCGTGTGGCCACCAGCTGGACATCTCTGCCACGAG GGCTGCTGACCCATCGCACCGCTCTCAAGGCGGCAGGTACAAGAGGGAGACTCTGAAGACGACAAAGTATGTGGAGCTT GTTATTGTGGCGGATAATCGTGAGTTTCAGAGACAAGGCAAGGATGTGGAAAAAATTAAGCAGAGGCTGATAGAAATTG CAAACTATGTCGATAAGTTCTATAGGCCGCTGAATATTCGAGTAGCCCTGGTTGGAGTGGAAGTGTGGAACGACATGGA TAAGTGCTCTATCTCTCAAGACCCTTTCACCAGC
Citation	Alev C, Wu Y, Kasukawa T, Jakt LM, Ueda HR, Sheng G. Transcriptomic landscape of the primitive streak. Development. 2010 Sep 1;137(17):2863-74. Epub 2010 Jul 28.
Copyright	Published by The Company of Biologists 2010. This material is protected by a copyright retained by the authors. Permission granted by Dr. G Sheng.
Comments	The probe for ADAM12 was amplified by PCR using the following primers: 5′-TCTCTCACGCAATTACACGG-3′ and 5′-GCTGGTGAAAGGGTCTTGAG -3′.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

stage 4

Neural Plate/Tube

Entry 7

GEISHA Id	ADAM12.Lin.2008	Data Source	Publication
Complete cDNA Template Probe	show ATGTCAAAGCGTCTCCTTGCGGAGCGGCAGCGCTCCCCCGCTCCGCGCCCCTCCGTGCTGCTGCTGAGCCTCAGCGCGC TGCTCCTAGCATCACCCCGAGCGCGAGGTCAGAATGTGGACAGCAAGTTGGAGTCCTTGAGACAGCAGATGCTGAAGGA CCAGTCAAAAGATTATGAGATAACAGTTCCCCTCCTTTTGAATGGAGAACAGTGGAGACCAGCAAACAGCATTTATTCC AAGAACCACCCGTCCCTGCTGCAGTTGGTGGTACAAGCTGAAGGGGAACGTCTGGTCATCCACCTGGAGAGGAACGAGG GCCTGCTAGCCAGCAGCTTCACAGAAACACATTATTTGAAGGATGGTACTGATGTGGTTCTCTCACGCAATTACACGGG TCACTGCTATTACCACGGCAATGTACGAGGGTACCCCAGTTCGTCAGTCAGTCTCAGTACCTGCTCTGGACTCAGGGGA ATTATTGTGTTTGAAAACAAAAGCTACATTCTGGAGCCGTTAGAAGGTGCTACAAGTGAACACAAGATCTACCGAGCAG AGAACTTGGAAATAATTCCAGGGTCGTGTGGCCACCAGCTGGACATCTCTGCCACGAGGGCTGCTGACCCATCGCACCG CTCTCAAGGCGGCAGGTACAAGAGGGAGACTCTGAAGACGACAAAGTATGTGGAGCTTGTTATTGTGGCGGATAATCGT GAGTTTCAGAGACAAGGCAAGGATGTGGAAAAAATTAAGCAGAGGCTGATAGAAATTGCAAACTATGTCGATAAGTTCT ATAGGCCGCTGAATATTCGAGTAGCCCTGGTTGGAGTGGAAGTGTGGAACGACATGGATAAGTGCTCTATCTCTCAAGA CCCTTTCACCAGCCTCCATGAGTTTCTGGACTGGAGAAAGCTAAAATTACTACCTCGTAAACCCCATGACAACGCACAG CTAATAAGCGGGGTGTACTTCCAGGGGACAACCATTGGCATGGCGCCCATCATGAGCATGTGCACTGCAGAGCAGTCTG GAGGGGTCGTCATGGATCATTCAGAAAACCCTCTTGGTGCAGCCGTCACCCTGGCTCATGAGCTGGGCCACAACTTCGG GATGAATCATGATACGTTGGAGAGGGGCTGCAACTGCAAAGCATCTACTGACAAAGGGGGCTGCATCATGAATCCTTCT ACAGGCTATCCATTTCCCATGGTGTTCAGCAGCTGCAGTAGAAAGGACCTGGAAAACAGCCTGGAGAAAGGAGTGGGAA TGTGTCTGTTTAACTTGCCTGAAGTCAAGGAGTCCTTTGGTGGACAGAAGTGTGGGAACGGCTACGTGGAAGATGGAGA GGAGTGCGACTGTGGGGAGCCCGATGAATGTACAAACCGGTGCTGCAACGCAACTACCTGCACTTTGAGGCCAGGAGCA GTGTGTGCACACGGACTTTGCTGCGAAGACTGCAAGTTAAAACCAGCGGGGATTTCTTGCAGAGAGTCGAGCAATTCCT GTGATCTGCCAGAGTTTTGCACTGGAGCCAGCCCTCACTGCCCAGCTAATGTGTACCTGCACGACGGGCACGCGTGCCA CGGGGTGGACGGCTACTGCTACAACGGCATCTGCCAGACCCACGAGCAGCAGTGCATCACCCTCTGGGGCCAGGGTGCC AAACCTGCTCCTGGGATCTGCTTTGAGAGAGTCAACTCTGCAGGTGATCCATACGGCAACTGTGGCAAAGACTCCAAGA GCTCCTTCGCCAAGTGTGAGCCCAGAGATGCTAAATGTGGAAAAATTCAGTGTCAAGGAGGAGCCAATCGACCTGTAAT TGGTACCAATGCTGTTTCCATAGAAACCAATATCCCACTTCAGGAAGGTGGGAAGATCCTGTGTCGTGGCACCCACGTG TATCTGGGGGATGACATGCCTGACCCTGGTCTCGTGCTGTCAGGAACCAAGTGTGAAGATGGAAAGATTTGCCTTAATC GCCGGTGCCAGAATACAAGTGTTTTTGGTGTGCATAAGTGTGCAACAAAGTGCCATGGACGTGGAGTTTGCAACAACAA AAAGAACTGTCACTGTGAGGCTGACTGGGCCCCCCCATACTGTGACAAGCCGGGCTTTGGTGGCAGCGTGGACAGCGGG CCCATCAGGCAAGCAGATAATAAGAGTTTAACCGTAGGAGTGTTGATCACCATTCTGTGCCTTACCTTTGCTGGGTCAG TCATGTATCTAAAAAGGAAGACTCTCATGAGATTGCTGTTTACAAGTAAGAAGACGACGATAGAGAAATTAAGGTCTGT GAGCCCAGCGAGATCTTCTAGATCATCTAAGCTCAATCACGTTCGTACCACATCTCTCAGTAAAAATCTCATGATGAAG CCACAAAATGCAAACGTGCAAAAAAGAGACGGCCCGAGGCGCCCGCTGCCCTATCAGATCGTTGACATCAGTGACCCGG TGAAGACACACCATGTGCCACAGCTGAAGACCCCACAGCGTGTCCTGCCACCCCTTCCTCAGCCGCCCTGCCACCAAGC TGGCCCTGAAAGGCCCCTTCCTGCTAACCCCACTCTCAGGCTCCCCCAGGAAAACCACAAGCCAAGCCCTCCTCGGAAG CCTCTACCAGCAGATCCCCTGAACAAAACTCGTTATAACAGTGCGTGCACCCCAGGGCTTGGACACACAAAAGCGCTGC CTCACATTGCTCCTGCAAGACCTGCTCCCAAGCATCCACCACCAGTACCCAGGTCCAGCAATGCTACTGCTGATGTGAA ATGAT
Citation	Lin J, Luo J, Redies C. Differential expression of five members of the ADAM family in the developing chicken brain. Neuroscience. 2008 Nov 19;157(2):360-75. doi: 10.1016/j.neuroscience.2008.08.053. Epub 2008 Sep 4.
Copyright	Copyright © 2008 IBRO. Published by Elsevier Ltd. All rights reserved.