GEISHA - A Chicken Embryo Gene Expression Database
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ALK
ALK receptor tyrosine kinase

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolALK
Official Full NameALK receptor tyrosine kinase
CGNC ID6869
also known asALK tyrosine kinase receptor|anaplastic lymphoma kinase (Ki-1)|anaplastic lymphoma receptor tyrosine kinase
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
Sequence Information
Genomic
RNAXM_419364
PolypeptideXP_419364
Gene Expression
In Situ HybridizationGEISHA
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human238ENSG00000171094MIM:256700MIM:105590
Mouse11682ENSMUSG00000055471All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2) MGI:103305
Xenopus100495071490261
Zebrafish563509ZDB-GENE-031027-1ZFIN:ZDB-GENE-031027-1
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene421297
Ensembl Gene
KEGGgga:421297

Entry 1

GEISHA IdALK.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerCCTTTCTTCTCCCATAGAGGACGAC
Reverse cDNA Template PrimerAATTAACCCTCACTAAAGGCGCTGGTCATTACAGTGCTTGCcDNA Template Length844
Forward cDNA Template Probeshow
GCTGGTGCTTNGTTGGTGTCAAGGGATCAGTGCATAATCTGCTACTGAAGGAAAACGGTTGTACTCCAGGCTCCCAATT
CGCCATGGAGAAGCACGGGACGCTGCTGAGCCCTCCATCCAGCCACAGTCCCCTTCTTCAAACGAACAGTAAAAGCCAG
AGGGAAGTTTTCTGCACATTGCTCCCTCGTCCTCTCCTTCAGTGCAGTCTCTGATGAAGTCACACGCCTGGCCCAGCCT
GATTGATGTGCCATTCCAGCAGCTGAAGGAACCTTCCAGAGCCATTTTTGAGACAGAAGCAGCTCCTGTAGTGCAGTTC
TTCATTGCAAAGGAATCCACAGCTGCTATGCTCTTGTTCCCTTTAGCAATGTACTCCAATGAGATCCGAAATGGTTTCT
CTCTATGTCCAACTCTTCTTTGAAGCAGCTCCCATCCACGTTTTTCTGGATTCTGCTCTGTCAAAATTTCACTGCTGCT
GCCGTCAATAGGAAGGATCCGAACAATATATTCTCCACTTTGCTGGAAAAACTTATAAACAGCCACTTGAACTACGCAT
TGGTCACTGCTGCTTCTCAGCCAAGGGCTCAGGATGACAGGGCTCTCAGACGCATTAAGGAACAGGAAAGAACCTTTTG
GTGTATTCTCAGAGTGATCTCTCTCTGGTCCACCCGGGATGTTCANCTGTGAAATATCCTCTGCACTCACTCTCANCCA
GGCTTTGTTGGGGCTTTCCTGATCTTTCNAGGAAAAGGAATATTCCANCTCACAAGGAGTCTCAAANTTGCAATCAAAT
ATATGTCNTCCTCTATGG
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
Unlabeled
 
7-12
stage 10
stage 10
stage 10
stage 10
stage 10
stage 11
stage 11
stage 11
Amnion
Anterior Intestinal Portal
Ear/Otic Placode
Ectoderm
Hindbrain
Neural Crest
Neural Plate/Tube
Notochord
Pharynx
Splanchnic Mesoderm
 
13-18
stage 16
Amnion
Neural Plate/Tube
 
19-24
stage 22
stage 22
stage 22
stage 22
Spinal Ganglia and Nerves
 
25
stage 25
Spinal Ganglia and Nerves
 

Entry 2

GEISHA IdALK.Hurley.2006Data SourcePublication
Complete cDNA Template Probeshow
ACTGGCTGTTCACAACATGTGGTGCTAGCGGAGCCTATGGCCCCACACAGAGCCAATGCAATGATGCCTACAGGAACTC
CAACCTCAGTGTGATCGTTGGAGCTGAGGGGATTCTCCAAGGTATTCAAATCTGGAGAGTACCAGCAACCAACACGTAC
AGCATCTCAGGTTATGGAGCTGCTGGTGGGAAAGGAGGGAAGAACACCATGGTGAGATCCCACGGCGTGTCTGTACTGG
GCATTTTTGACCTCCAGAAGGATGATACGTTATATATCTTGGTGGGACAGCAAGGAGAAGATGCTTGCCCTAGTACTAA
TGACGTTATACAGAAAGTCTGCATTGGAGAGAACAACGTGATTGAAGAGGAGATACGTGTGAACAGAAGTGTCAATGAA
TGGGCAGGAGGAGGTGGAGGCGGGGGAGGTGCAACTTATATATTTAAGATGGAGAATGGAGAACCGGTCCCCCTGATAA
TTGCAGCAGGAGGTGGTGGCAGGGCCTACAGGGCCAAAACAGACACATTTCATCCAGAAAGGCTGGAGAATGATTCCTC
TGTTCCAGGGCTGAATGGAAATTCAGGAGCTGCAGGTGGTGGAGGTGGCTGGAATGATAACACTTCCTTCCTGTGGTCA
GGAAAATCCTTGCTGGAAGGTGCTACTGGAGGAAGATC
CitationHurley SP, Clary DO, Copie V, Lefcort F. Anaplastic lymphoma kinase is dynamically expressed on subsets of motor neurons and in the peripheral nervous system. J Comp Neurol. 2006 Mar 10;495(2):202-12.
CopyrightCopyright 2006 Wiley-Liss, Inc.
CommentsThe cDNA template used to generate the probe was obtained by PCR as described in Hurley et al.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 19
stage 19
stage 19
stage 22
stage 22
stage 23
stage 23
stage 23
stage 23
stage 23
stage 23
stage 23
stage 23
stage 24
stage 24
stage 24
stage 24
stage 24
Spinal Cord
Spinal Ganglia and Nerves
double labeled
25-30
stage 25
stage 25
stage 25
stage 25
stage 25
Spinal Cord
Spinal Ganglia and Nerves
 
31-44
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 35
stage 39
stage 39
stage 39
stage 39
stage 39
stage 39
stage 44
stage 44
Leg Muscles
Myotome
Spinal Cord
Spinal Ganglia and Nerves
Trunk Mesenchyme
caudofemoralis (C; arrowheads)
fibularis longus (D; black arrowhead)
iliotibialis cranialis (A; arrowhead)
iliotibialis lateralis (B; arrowhead)
intercostals (E; arrowheads)

Entry 3

GEISHA IdALK.Apostolova.2007Data SourcePublication
Complete cDNA Template Probeshow
ATACAGAGCCAGCTACTATCGGAAGGGAGGGTGTGCGATGCTGCCTGTCAAATGGATGCCTCCCGAGGCTTTCATGGAA
GGGATATTTACATCAAAAACAGACACATGGTCCTTTGGCGTATTGCTGTG
CitationApostolova G, Dorn R, Ka S, Hallböök F, Lundeberg J, Liser K, Hakim V, Brodski C, Michaelidis TM, Dechant G. Neurotransmitter phenotype-specific expression changes in developing sympathetic neurons. Mol Cell Neurosci. 2007 Jul;35(3):397-408. Epub 2007 Apr 1.
CopyrightCopyright © 2007 Elsevier Inc. All rights reserved.
CommentsThe probe was amplified by PCR using the following primers: 5'-ATA CAG AGC CAG CTA CTA TCG G-3' and 5'-CAC AGC AAT ACG CCA AAG GAC-3' and was extracted from NCBI Acc# XM_004940187.1.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-44
stage 44
stage 44
Spinal Ganglia and Nerves
 

Entry 4

GEISHA IdALK.Cui.2019Data SourcePublication
Complete cDNA Template Probeshow
ACTGGCTGTTCACAACATGTGGTGCTAGCGGAGCCTATGGCCCCACACAGAGCCAATGCAATGATGCCTACAGGAACTC
CAACCTCAGTGTGATCGTTGGAGCTGAGGGGATTCTCCAAGGTATTCAAATCTGGAGAGTACCAGCAACCAACACGTAC
AGCATCTCAGGTTATGGAGCTGCTGGTGGGAAAGGAGGGAAGAACACCATGGTGAGATCCCACGGCGTGTCTGTACTGG
GCATTTTTGACCTCCAGAAGGATGATACGTTATATATCTTGGTGGGACAGCAAGGAGAAGATGCTTGCCCTAGTACTAA
TGACGTTATACAGAAAGTCTGCATTGGAGAGAACAACGTGATTGAAGAGGAGATACGTGTGAACAGAAGTGTCAATGAA
TGGGCAGGAGGAGGTGGAGGCGGGGGAGGTGCAACTTATATATTTAAGATGGAGAATGGAGAACCGGTCCCCCTGATAA
TTGCAGCAGGAGGTGGTGGCAGGGCCTACAGGGCCAAAACAGACACATTTCATCCAGAAAGGCTGGAGAATGATTCCTC
TGTTCCAGGGCTGAATGGAAATTCAGGAGCTGCAGGTGGTGGAGGTGGCTGGAATGATAACACTTCCTTCCTGTGGTCA
GGAAAATCCTTGCTGGAAGGTGCTACTGGAGGAAGATC
CitationCui R, Lwigale P. Expression of the heparin-binding growth factors Midkine and pleiotrophin during ocular development. Gene Expr Patterns. 2019 Jun;32:28-37. Epub 2019 Feb 27. DOI: 10.1016/j.gep.2019.02.001.
CopyrightCopyright © 2019 Elsevier B.V. 
CommentsThe complete cDNA template sequence was obtained from the information provided in the publication as described in Cui et al. 2019.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31
stage 31
Retina
 
all
 
  

Mouse

EmageMGI:103305
MGI GXDMGI:103305

Frog

Xenbase490261

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-031027-1
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