GEISHA - A Chicken Embryo Gene Expression Database
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TGFBR1
transforming growth factor beta receptor 1

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolTGFBR1
Official Full Nametransforming growth factor beta receptor 1
CGNC ID9575
also known asChALK5, TGF-beta receptor type-1|Activin like receptor kinase 5|transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204246
PolypeptideNP_989577
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.143
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly35900FBgn0011300
Human7046ENSG00000106799MIM:609192MIM:190181
Mouse21812ENSMUSG00000007613All phenotypic alleles (8):Targeted, knock-out(3) Targeted, other(4) Gene trapped(1) MGI:98728
Xenopus548715, 399295478586
Zebrafish792928, 560578ENSDARG00000042259, ENSDARG00000017494ZDB-GENE-091027-1, ZDB-GENE-051120-75ZFIN:ZDB-GENE-091027-1, ZFIN:ZDB-GENE-051120-75
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene374094
Ensembl GeneENSGALG00000012617
KEGGgga:374094

Entry 1

GEISHA IdTGFBR1.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerTATGGCGTTACGGGGCAC TC
Reverse cDNA Template PrimerAATTAACCCTCACTAAAGGTGTTCGTGATAATCTGACACCAACCcDNA Template Length855
Complete cDNA Template Probeshow
TTTTTTAAAAGCTGCGGCCGCAGAATATTATGGCGTTACGGGGCACTGGCGGCTCCGGGCCCTGCTGCGCCTGCTGGTA
GCCGCGGTCCTGCTGCCCAGGGCGGCCGCATTACAATGTTACTGCCATCTATGCACAAAGGACAACTTTACCTGTTGTG
ACAGATGGGCTTTGTTTTACCTCTGTAACACGGACTGCAGATAGAGTCATACGCAATAGCATGTGTATAGCAGAAATTG
ATCTGATTCCTCGAGACAGGCCATTTATTTGTGCACCATCCTTCAGAGATGGAGTTACTACTTTGCCTCATTGCTGTGA
CAGAGACCACTGCAATAAAATAGAACTTCCAATTCCAACACCAGGTCCTACTCCAGGAAGACCAGCTTCTAGTCTAGGA
CCTGTGGAACTGGCAGCTGTTATTGCTGGACCTGTCTGCTTTGTCTGCATTTCATTGATGCTGATTCTGTATCTTTGTC
ATAACCGTACTGTAATTCATCATCGTGTGCCAAGTGAAGAAGATCCTTCATTGGATCGTCCCTTTATATCTGAAGGAAC
TACTTTGAAGGATTTAATTTATGATATGACAACTTCAGGCTCTGGATCAGGTTTACCTTTACTTGTGCAAAGAACAATT
GCACGAACTATAGTACTCCAAGAAAGTATTGGTAAGGGTCGCTTTGGAGAAGTATGGAGGGGGAAATGGAGAGGAGAAG
AAGTTGCTGTGAAGATCTTCTCTTCAAGAGAAGAGCGCTCATGGTTTCGAGAGGCAGAAATTTATCAAACCAGTTATGC
TACGACATGAAAAACATTGCTTGGATTCATAGCTGCGGACAACCAAAACAATGGTACCATGGACGCAGGTGTTGGTGTC
AGATTATCACGAACACCTTTAGTGAGGGTTATTTTTAAAAC
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
1-3
stage 3
stage 3
Area Pellucida
Primitive Streak
 
4-6
stage 5
Area Opaca
Area Pellucida
 
7-12
stage 9
stage 10
stage 12
Area Pellucida
Blood Vessels
Heart Tube
Lateral Plate Mesoderm
Neural Plate/Tube
Somites
 
13-18
stage 15
stage 17
stage 18
Ubiquitous Embryonic
 
19-24
stage 19
  
25
stage 25
Widespread Expression
 

Entry 2

GEISHA IdALK5.Desgrosellier.2005Data SourcePublication
Complete cDNA Template Probeshow
CATCTATGCACAAAGGACAACTTTACCTGTGTGACAGATGGGCTTTGTTTTACCTCTGTAACACGGACTGCAGATAGAG
TCATACGCAATAGCATGTGTATAGCAGAAATTGATCTGATTCCTCGAGACAGGCCATTTATTTGTGCACCATCCTTCAG
AGATGGAGTTACTACTTTGCCTCATTGCTGTGACAGAGACCACTGCAATAAAATAGAACTTCCAATTCCAACACCAGGT
CCTACTCCAGGAAGACCAGCTTCTAGTCTAGGACCTGTGGAACTGGCA
CitationDesgrosellier JS, Mundell NA, McDonnell MA, Moses HL, Barnett JV. (2005) Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. Dev Biol. 2005 Apr 1;280(1):201-10.
CopyrightCopyright © 2005 Elsevier Inc. All rights reserved.
CommentsAccording to the authors, "Probes were as follows: ... chicken ALK5 (GenBank Accession # D14460; nt 184–468)." The sequence below was obtained from NCBI using the information provided.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 14
Aorta
Endocardium
Neural Plate/Tube
Ventricles
 
19
stage 19
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.143

Mouse

EmageMGI:98728
EurexpressMGI:98728
MGI GXDMGI:98728

Frog

Xenbase478586

Fruit Fly

BDGPFBgn0011300

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-091027-1, ZDB-GENE-051120-75
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