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APCDD1
APC down-regulated 1

Gene

Official Symbol	APCDD1
Official Full Name	APC down-regulated 1
CGNC ID	52884
also known as	Pgo1, cAPCDD1, protein APCDD1\|APCDD1 homologue\|adenomatosis polyposis coli down-regulated 1 protein homolog\|primglo1\|protein primglo1
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.31957

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	147495			MIM:607479
Mouse	494504	ENSMUSG00000071847	All phenotypic alleles (4):Targeted, knock-out(1) Targeted, other(3)	MGI:3513977
Xenopus	448576, 447402			5762129
Zebrafish	100332639		ZDB-GENE-130806-1	ZFIN:ZDB-GENE-130806-1

Gene Ontology

Molecular Function	Wnt-protein binding
Biological Process	astrocyte cell migration, hair follicle development, negative regulation of Wnt signaling pathway, more...Wnt signaling pathway
Cellular Component	integral component of plasma membrane

Links to other databases

GEISHA Id	DRAPC.Quinlan.2009	Data Source	Publication
Complete cDNA Template Probe	show CATGGAGGGCTTTCAAGGAGTCACAGTGTCATCACATGCTGAAACACCTCCACAATGGGGCCCGCATCACTGTGCAAAT GCCTCCCAATATAGAGGGACACTGGGTCTCTACCGGCTGTGAAGTCAGAGCAGGTCCAGAGTTCATCACAAGGTCCTAC AGATTCTATCACAATAATACATTTAAAGCATATCAGTTTTACTATGGTGGCAATCGCTGCACTAACCCTATCTACACAT TAGTTATACGTGGCAAAATTCGTCTCCGCCAAGCATCCTGGATCATCCGAGGGGGTACTGAAGCTGATTATCAGCTGCG CAACATACAGATCATAAGCCACAATGAAGCAGTAGCCAAAAAATTAAGTGAGTTGGTCAACAATACATGTCCTGGATTT ATACCGGAAGATAGTCCCTGGGAGCAGGATGTGAGCTATGATTTGCTCAGAGAAGAGAATGGCTGTGAATGCACCAAGG CTCTGAATTTGCCATGCATGAACTCCAGCTGATCCGGGTGGAGAAGCAATATCTGCATCACAATTTAGATCACCTCGTG GAGGAGCTATTTCTTGGAGACATTCATACTGATGCTACCCAGAGGAGGTACTACCGACCCTCCAGTTACCAGCCTCCTC TTCAAAATGCCAAGAACCATGACCGCACGTGCATTGCATGCAGGATCATCTACCGCTCCGATGAGCACCACCCACCATC CTGCCC
Citation	Quinlan R, Graf M, Mason I, Lumsden A, Kiecker C. Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev. 2009 Sep 4;4:35.
Copyright	Copyright © 2009 Quinlan et al; licensee BioMed Central Ltd. [This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.]
Comments	Authors indicated DRAPC probe came from ChEST357h24. According to NCBI, this is GenBank Acc# BU356566.1.

Stage

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Comments (click to highlight)

19-22

stage 22

GEISHA Id	APCDD1.Anderson.2020	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show GTCACATCTTTCACACTTGTTCTCAGGCATGAAAAACTGCAGAAAGCCCATGAAAGCTCAAGAGTCAGAATGAAAGCCC AGGATGGCCGAGCAGTGCTCCTCCACACACCTGATCATTGCAGGGGAGTTGGACTAAATGGCCTTCAGAGGTCCCTTCC AACTCTCAGGATTCTGTGATTCTATAACTACGTGTCTTGTTCTTACCTCAAAGAAGTGCATTCACATGTGCACTACAGC AGTTAAACCCTTGTTTGTGAAGCACAGGCTTGCAAAGATCTAGGTTTGCCAAGACATGGGGCTACACTACACACAAACA TGACACAGATTGTGCAAACTGTACAAGAAATGCATTTCTTTTTCCTACCATTTAGAGATGGTTGAAAAGGAAGCACTAG AAAAAGACCTTCATAATGCACTGCAAATAATCCAATTCAGGTTTGTTTTGGCTCTGGTACACAATGGCTCTTCTGGTTT ATTTGTATCATCGACTTGAAACATAATTCTGTGATTTAGGTTCCTAGCATCTGCTGCCCCGTCTTTCCTCCTTGGGTCT GTATTTTCCCTTTATTTTGCTGTTAGCCAACAGAAGCCAAGTTGGACAAAGTTATGTCAGCCTTAAGAGCATGTGGTTT ACTTGTCAGTCCCTGTGCTCTGTGAGGGTTCTGCTCGGTTACAGGCGCAGAACTAGGTGCTGAGCTCCCCTGATCTTCC CATTTCATCAGGCACTAAAATTAACCGCCGCACGGCATATGCATTTGTGATACAATATTTTCCATTCATTTTGTTCCTT CGGCCTGGACTCCATGTGCT
Comments	Images Provided by Claire Anderson; Related article:Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.

Stage

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Location (click to highlight)

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7-12

stage 12

GEISHA Id	APCDD1.Anderson.2019	Data Source	Publication
Complete cDNA Template Probe	show GTCACATCTTTCACACTTGTTCTCAGGCATGAAAAACTGCAGAAAGCCCATGAAAGCTCAAGAGTCAGAATGAAAGCCC AGGATGGCCGAGCAGTGCTCCTCCACACACCTGATCATTGCAGGGGAGTTGGACTAAATGGCCTTCAGAGGTCCCTTCC AACTCTCAGGATTCTGTGATTCTATAACTACGTGTCTTGTTCTTACCTCAAAGAAGTGCATTCACATGTGCACTACAGC AGTTAAACCCTTGTTTGTGAAGCACAGGCTTGCAAAGATCTAGGTTTGCCAAGACATGGGGCTACACTACACACAAACA TGACACAGATTGTGCAAACTGTACAAGAAATGCATTTCTTTTTCCTACCATTTAGAGATGGTTGAAAAGGAAGCACTAG AAAAAGACCTTCATAATGCACTGCAAATAATCCAATTCAGGTTTGTTTTGGCTCTGGTACACAATGGCTCTTCTGGTTT ATTTGTATCATCGACTTGAAACATAATTCTGTGATTTAGGTTCCTAGCATCTGCTGCCCCGTCTTTCCTCCTTGGGTCT GTATTTTCCCTTTATTTTGCTGTTAGCCAACAGAAGCCAAGTTGGACAAAGTTATGTCAGCCTTAAGAGCATGTGGTTT ACTTGTCAGTCCCTGTGCTCTGTGAGGGTTCTGCTCGGTTACAGGCGCAGAACTAGGTGCTGAGCTCCCCTGATCTTCC CATTTCATCAGGCACTAAAATTAACCGCCGCACGGCATATGCATTTGTGATACAATATTTTCCATTCATTTTGTTCCTT CGGCCTGGACTCCATGTGCT
Citation	Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Copyright	Copyright © 2019 Elsevier Inc. All rights reserved.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Anderson et al. 2019.