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Human Disease Gene Search
ALX4 The human orthologue of this gene is associated
Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol ALX4 Official Full Name ALX homeobox 4 CGNC ID 48987 also known as homeobox protein aristaless-like 4|aristaless-like homeobox 4, ALX4
gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id Alx4.Bothe.2006 Data Source Publication Complete cDNA Template Probe show ATGAATGCTGATACTTGTGTTTCTTATTGTGATCCGGCTGCCATGGATTCCTACTACAACGCAGCCTCCCAGGGCGCAG
Citation Bothe I, Dietrich S. The molecular setup of the avian head mesoderm and its implication for craniofacial myogenesis. Dev Dyn. 2006 Oct;235(10):2845-60. Copyright Copyright © 2006 Wiley-Liss, Inc. Comments Insufficient information provided to verify exact probe sequence. Sequence obtained from NCBI (NM_204162).
Entry 2 GEISHA Id Alx4.Ahmed.2006 Data Source Publication Complete cDNA Template Probe show ATGAATGCTGATACTTGTGTTTCTTATTGTGATCCGGCTGCCATGGATTCCTACTACAACGCAGCCTCCCAGGGCGCAG
Citation Ahmed MU, Cheng L, Dietrich S. Establishment of the epaxial-hypaxial boundary in the avian myotome. Dev Dyn. 2006 Jul;235(7):1884-94. Copyright Copyright © 2006 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence was obtained from NCBI (NM_204162).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 20
stage 22
stage 24
Dermatome Myotome 25 stage 25
Dermatome Myotome
Entry 3 GEISHA Id ALX4.Bothe.2007 Data Source Publication Complete cDNA Template Probe show ATGAATGCTGATACTTGTGTTTCTTATTGTGATCCGGCTGCCATGGATTCCTACTACAACGCAGCCTCCCAGGGCGCAG
Citation Bothe I, Ahmed MU, Winterbottom FL, von Scheven G, Dietrich S. Extrinsic versus intrinsic cues in avian paraxial mesoderm patterning and differentiation. Dev Dyn. 2007 Sep;236(9):2397-409. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204162).
Entry 4 GEISHA Id Alx4.Cheng.2004 Data Source Publication Complete cDNA Template Probe show ATGAATGCTGATACTTGTGTTTCTTATTGTGATCCGGCTGCCATGGATTCCTACTACAACGCAGCCTCCCAGGGCGCAG
Citation Cheng L, Alvares LE, Ahmed MU, El-Hanfy AS, Dietrich S. The epaxial-hypaxial subdivision of the avian somite. Dev Biol. 2004 Oct 15;274(2):348-69. Copyright Reprinted from Developmental Biology, Volume 274, Issue 2, Louise Cheng, Lúcia E. Alvares, Mohi U. Ahmend, Amira S. El-Hanfy, and Susanne Dietrich, The epaxial-hypaxial subdivision of the avian somite, Pages 348-369, Copyright 2004, with permission from Elsevier.
Copyright © 2004 Elsevier B.V. All rights reserved. Comments Authors indicate the probe is from Takahashi et al., 1998, who said: A plasmid containing chick Alx-4 was genbank Acc #AF092538 linearized with BamHI (no internal site).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 7
Dermomyotome 19-20 stage 20
Entry 5 GEISHA Id ALX4.Bothe.2011 Data Source Publication Complete cDNA Template Probe show ATGAATGCTGATACTTGTGTTTCTTATTGTGATCCGGCTGCCATGGATTCCTACTACAACGCAGCCTCCCAGGGCGCAG
Citation Bothe I, Tenin G, Oseni A, Dietrich S., Dynamic control of head mesoderm patterning., Development. 2011 Jul;138(13):2807-21. Copyright Permission from the authors and the Company of Biologists Ltd. Copyright held by the authors. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204162).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
stage 10
stage 10
stage 10
Head Mesenchyme Neural Plate/Tube
Entry 6 GEISHA Id ALX4.McGonnell.2011 Data Source Publication Complete cDNA Template Probe show ATGAATGCTGATACTTGTGTTTCTTATTGTGATCCGGCTGCCATGGATTCCTACTACAACGCAGCCTCCCAGGGCGCAG
Citation McGonnell IM, Graham A, Richardson J, Fish JL, Depew MJ, Dee CT, Holland PW, Takahashi T.. Evolution of the Alx homeobox gene family: parallel retention and independent loss of the vertebrate Alx3 gene. Evol Dev. 2011 July; 13(4): 343351. Copyright Copyright © 2011 Wiley Periodicals, Inc.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-23 stage 23
stage 23
Data from NCBI Unigene EST ProfileGga.934
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