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TFAP2A
transcription factor AP-2 alpha

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolTFAP2A
Official Full Nametranscription factor AP-2 alpha
CGNC ID9685
also known asTFAP2, transcription factor AP-2-alpha|AP-2 transcription factor|transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)|transcription factor AP2, AP-2 transcription factor, TFAP2a, transcription factor AP-2 alpha
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205094
PolypeptideNP_990425
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.2351
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly40398FBgn0261953
Human7020ENSG00000137203MIM:113620MIM:107580
Mouse21418ENSMUSG00000021359All phenotypic alleles (7):Chemically induced(1) Targeted, knock-out(2) Targeted, other(4) MGI:104671
Xenopus395064, 503683, 394344481200
Zebrafish140618ENSDARG00000059279ZDB-GENE-011212-6ZFIN:ZDB-GENE-011212-6
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene395982
Ensembl Gene
KEGGgga:395982

Entry 1

GEISHA IdAp2.Chapman.2008Data SourceDirect Submission
Complete cDNA Template Probeshow
CGAGGCTCAGCGCACAGCGGCTCTGCACAGTCCGCCGCGCTCCGCAGCACCGCGCCGGGGGGATCGGACCCTCTCCCGC
CGACCCATGAAAATGCTCTGGAAGCTGACGGATAACATCAAGTACGAGGAGTGCGAGGAGCGCCACGACAGTGCCAGCA
ACGGGACGGCGCGGCTGCCCCAGCTGGGGGCCGTGGGGCAGTCCCCGTATAGCAGCGCCCCGCCGCTCTCGCACACCCC
CAACGCCGACTTCCAGCCGCCCTACTTCCCCCCCCCGTACCAGCCCATCTACCCCCAGTCTCAGGACCCCTACTCCCAC
GTCAACGACCCCTACAGCCTCAACTCCCTGCACACCCAGCCGCAGCCCCAGCACCCGGCGTGGCCGGGCCAGAGGCAGA
GCCAGGAGCCGAGCTTGCTGCACGCGCACCGGGGGCTGCCCCACCAGCTGGGGGGGTTGGACCCCCGCCGCGACTACCG
GCGGCACGACGACCTGCTGCACGGCCCGCACGGGCTGGGAGCGGGGCTGGCCGACCTGCCGCTGCACTCCATCCCTCAC
GCCATCGAGGACGTGCCGCACGTAGACGACCCCGGCATCAACATCCCGGACCAGACCGTCATTAAGAAAGGCCCCGTGT
CCCTCTCCAAGTCTAACAACAACGCCGTCTCCTCCATCCCCATCAACAAGGACGCGCTCTTCGGCGGGGTGGTGAACCC
CAACGAGGTCTTCTGCTCGGTGCCGGGCCGCCTCTCGCTGCTCAGCTCCACCTCCAAGTACAAGGTCACGGTGGCGGAA
GTGCAGCGACGCCTCTCGCCGCCCGAGTGCCTCAACGCCTCCCTGCTGGGCGGAGTGCTGAGGAGGGCAAAGTCCAAAA
ATGGCGGGAGGTCCCTCCGAGAGAAGCTGGACAAGATAGGGTTGAACCTGCCGGCCGGGAGGCGCAAAGCTGCTAATGT
CACCTTGCTCACCTCGCTGGTGGAGGGGGAAGCAGTGCATCTAGCTAGAGATTTTGGGTACGTTTGTGAGACAGAATTT
CCTGCCAAAGCAGTAGCTGAATTTCTCAACCGACAACATTCCGATCCAAACGAGCAAGTCACAAGAAAAAACATGCTTC
TAGCTACAAAACAGATCTGTAAAGAGTTCACCGACCTGCTGGCTCAGGACCGATCTCCCCTGGGGAACTCGCGGCCCAA
CCCCATTTTGGAGCCGGGCATCCAGAGCTGCCTGACCCACTTCAACCTCATCTCGCACGGCTTCGGGAGCCCGGCGGTA
TGCGCTGCCGTCACCGCCCTGCAGAACTATCTCACCGAGGCGCTCAAGGCCATGGACAAAATGTACCTCAGCAACAACC
CCAACAGCCACACAGACAACAGCACCAAAAGCAGCGACAAAGAGGAGAAGCACCGAAAGTGAGGATTCCCCCCCACTCC
TCTCCCTTCCCCCCCTCGCAGCCCATCAGTCCATTCACTCTCCCTCCTCCCTCTGCCCTGCACCCAGCACCCCAGGCTA
CGGCAACAGAATGAGCATCCTTCTGCCAATCCTGTTCTCTGACTCTGCGAGACCGCTCTGCCCTCATCCCCGCGACCCC
CTTCCCTGGCATCCACATCTTCATTTGCTCCCACTTTTAACTCGTTCCCCCTCTCCCGCTGCACCATCGTTTTGCTACC
CCAGTTTGGAGCCTAAGAGAACAGAAAACAGGGGGACGGAGCCAGCAAAAAGTAAAAGTTCTGTCTTGAGTTTGTGAAC
TTTTTTTTTTAAATAAAACAAAAGGAGGAAAAAAAAAAACAAAACAAAACGAAAAAAAAAAACAAAAGGACTTTTTTTT
TCTAAAAATATATTAAAAAACCTAAAAAAAAAAAAAAAAAA
CommentsImages Provided by Susan Chapman
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4
stage 4
Area Opaca
Area Pellucida
Extraembryonic
 

Entry 2

GEISHA IdAP-2α.Khudyakov.2009Data SourcePublication
Complete cDNA Template Probeshow
ACCAGACCGTCATTAAGAAAGGCCCCGTGTCCCTCTCCAAGTCTAACAACAACGCCGTCTCCTCCATCCCCATCAACAA
GGACGCGCTCTTCGGCGGGGTGGTGAACCCCAACGAGGTCTTCTGCTCGGTGCCGGGCCGCCTCTCGCTGCTCAGCTCC
ACCTCCAAGTACAAGGTCACGGTGGCGGAAGTGCAGCGACGCCTCTCGCCGCCCGAGTGCCTCAACGCCTCCCTGCTGG
GCGGAGTGCTGAGGAGGGCAAAGTCCAAAAATGGCGGGAGGTCCCTCCGAGAGAAGCTGGACAAGATAGGGTTGAACCT
GCCGGCCGGGAGGCGCAAAGCTGCTAATGTCACCTTGCTCACCTCGCTGGTGGAGGGGGAAGCAGTGCATCTAGCTAGA
GATTTTGGGTACGTTTGTGAGACAGAATTTCCTGCCAAAGCAGTAGCTGAATTTCTCAACCGACAACATTCCGATCCAA
ACGAGCAAGTCACAAGAAAAAACATGCTTCTAGCTACAAAACAGATCTGTAAAGAGTTCACCGACCTGCTGGCTCAGGA
CCGATCTCCCCTGGGGAACTCGCGGCCCAACCCCATTTTGGAGCCGGGCATCCAGAGCTGCCTGACCCACTTCAACCTC
ATCTCGCACGGCTTCGGGAGCCCGGCGGTATGCGCTGCCGTCACCGCCCTGCAGAACTATCTCACCGAGGCGCTCAAGG
CCATGGACAAAATGTACCTCAGCAACAACCCCAAACAGCCACACAGACAACAGCACCAAAAGCAGCGACAAAGAGGAAA
AGCACCGAAG
CitationKhudyakov J, Bronner-Fraser M. Comprehensive spatiotemporal analysis of early chick neural crest network genes. Dev Dyn. 2009 Mar;238(3):716-23.
CopyrightPublished Online: 22 Feb 2009 Copyright © 2009 Wiley-Liss, Inc.
CommentsThe sequence below was obtained from NCBI (BU230321) using the information provided in the publication.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 4
stage 4
stage 4
stage 5
stage 6
Ectoderm
Non-neural Ectoderm
Preplacodal Region
7-10
stage 7
stage 7
stage 8
stage 9
stage 10
stage 10
Ectoderm
Neural Crest
Neural Plate/Tube
Non-neural Ectoderm
Non-neural Ectoderm

Entry 3

GEISHA IdAP2alpha.Blentic.2008Data SourcePublication
Complete cDNA Template Probeshow
CGAGGCTCAGCGCACAGCGGCTCTGCACAGTCCGCCGCGCTCCGCAGCACCGCGCCGGGGGGATCGGACCCTCTCCCGC
CGACCCATGAAAATGCTCTGGAAGCTGACGGATAACATCAAGTACGAGGAGTGCGAGGAGCGCCACGACAGTGCCAGCA
ACGGGACGGCGCGGCTGCCCCAGCTGGGGGCCGTGGGGCAGTCCCCGTATAGCAGCGCCCCGCCGCTCTCGCACACCCC
CAACGCCGACTTCCAGCCGCCCTACTTCCCCCCCCCGTACCAGCCCATCTACCCCCAGTCTCAGGACCCCTACTCCCAC
GTCAACGACCCCTACAGCCTCAACTCCCTGCACACCCAGCCGCAGCCCCAGCACCCGGCGTGGCCGGGCCAGAGGCAGA
GCCAGGAGCCGAGCTTGCTGCACGCGCACCGGGGGCTGCCCCACCAGCTGGGGGGGTTGGACCCCCGCCGCGACTACCG
GCGGCACGACGACCTGCTGCACGGCCCGCACGGGCTGGGAGCGGGGCTGGCCGACCTGCCGCTGCACTCCATCCCTCAC
GCCATCGAGGACGTGCCGCACGTAGACGACCCCGGCATCAACATCCCGGACCAGACCGTCATTAAGAAAGGCCCCGTGT
CCCTCTCCAAGTCTAACAACAACGCCGTCTCCTCCATCCCCATCAACAAGGACGCGCTCTTCGGCGGGGTGGTGAACCC
CAACGAGGTCTTCTGCTCGGTGCCGGGCCGCCTCTCGCTGCTCAGCTCCACCTCCAAGTACAAGGTCACGGTGGCGGAA
GTGCAGCGACGCCTCTCGCCGCCCGAGTGCCTCAACGCCTCCCTGCTGGGCGGAGTGCTGAGGAGGGCAAAGTCCAAAA
ATGGCGGGAGGTCCCTCCGAGAGAAGCTGGACAAGATAGGGTTGAACCTGCCGGCCGGGAGGCGCAAAGCTGCTAATGT
CACCTTGCTCACCTCGCTGGTGGAGGGGGAAGCAGTGCATCTAGCTAGAGATTTTGGGTACGTTTGTGAGACAGAATTT
CCTGCCAAAGCAGTAGCTGAATTTCTCAACCGACAACATTCCGATCCAAACGAGCAAGTCACAAGAAAAAACATGCTTC
TAGCTACAAAACAGATCTGTAAAGAGTTCACCGACCTGCTGGCTCAGGACCGATCTCCCCTGGGGAACTCGCGGCCCAA
CCCCATTTTGGAGCCGGGCATCCAGAGCTGCCTGACCCACTTCAACCTCATCTCGCACGGCTTCGGGAGCCCGGCGGTA
TGCGCTGCCGTCACCGCCCTGCAGAACTATCTCACCGAGGCGCTCAAGGCCATGGACAAAATGTACCTCAGCAACAACC
CCAACAGCCACACAGACAACAGCACCAAAAGCAGCGACAAAGAGGAGAAGCACCGAAAGTGAGGATTCCCCCCCACTCC
TCTCCCTTCCCCCCCTCGCAGCCCATCAGTCCATTCACTCTCCCTCCTCCCTCTGCCCTGCACCCAGCACCCCAGGCTA
CGGCAACAGAATGAGCATCCTTCTGCCAATCCTGTTCTCTGACTCTGCGAGACCGCTCTGCCCTCATCCCCGCGACCCC
CTTCCCTGGCATCCACATCTTCATTTGCTCCCACTTTTAACTCGTTCCCCCTCTCCCGCTGCACCATCGTTTTGCTACC
CCAGTTTGGAGCCTAAGAGAACAGAAAACAGGGGGACGGAGCCAGCAAAAAGTAAAAGTTCTGTCTTGAGTTTGTGAAC
TTTTTTTTTTAAATAAAACAAAAGGAGGAAAAAAAAAAACAAAACAAAACGAAAAAAAAAAACAAAAGGACTTTTTTTT
TCTAAAAATATATTAAAAAACCTAAAAAAAAAAAAAAAAAA
CitationBlentic A, Tandon P, Payton S, Walshe J, Carney T, Kelsh RN, Mason I, Graham A. The emergence of ectomesenchyme. Dev Dyn. 2008 Mar;237(3):592-601.
CopyrightCopyright © 2008 John Wiley & Sons, Inc. All Rights Reserved.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_205094)
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 15
Neural Crest
Pharyngeal Arches and Clefts
 
19
stage 19
Neural Crest
Pharyngeal Arches and Clefts
 

Entry 4

GEISHA IdTFAP2A.Trevers.2023Data SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
ACCAGACCGTCATTAAGAAAGGCCCCGTGTCCCTCTCCAAGTCTAACAACAACGCCGTCTCCTCCATCCCCATCAACAA
GGACGCGCTCTTCGGCGGGGTGGTGAACCCCAACGAGGTCTTCTGCTCGGTGCCGGGCCGCCTCTCGCTGCTCAGCTCC
ACCTCCAAGTACAAGGTCACGGTGGCGGAAGTGCAGCGACGCCTCTCGCCGCCCGAGTGCCTCAACGCCTCCCTGCTGG
GCGGAGTGCTGAGGAGGGCAAAGTCCAAAAATGGCGGGAGGTCCCTCCGAGAGAAGCTGGACAAGATAGGGTTGAACCT
GCCGGCCGGGAGGCGCAAAGCTGCTAATGTCACCTTGCTCACCTCGCTGGTGGAGGGGGAAGCAGTGCATCTAGCTAGA
GATTTTGGGTACGTTTGTGAGACAGAATTTCCTGCCAAAGCAGTAGCTGAATTTCTCAACCGACAACATTCCGATCCAA
ACGAGCAAGTCACAAGAAAAAACATGCTTCTAGCTACAAAACAGATCTGTAAAGAGTTCACCGACCTGCTGGCTCAGGA
CCGATCTCCCCTGGGGAACTCGCGGCCCAACCCCATTTTGGAGCCGGGCATCCAGAGCTGCCTGACCCACTTCAACCTC
ATCTCGCACGGCTTCGGGAGCCCGGCGGTATGCGCTGCCGTCACCGCCCTGCAGAACTATCTCACCGAGGCGCTCAAGG
CCATGGACAAAATGTACCTCAGCAACAACCCCAAACAGCCACACAGACAACAGCACCAAAAGCAGCGACAAAGAGGAAA
AGCACCGAAG
CommentsThe complete cDNA template sequence was obtained from the information from the publication as described in Trevers et al. 2023.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
X-XIV
stage XII
Area Opaca
area opaca (strongest anteriorly)
1-3
stage 3
Area Opaca
area opaca
4-6
stage 5
Ectoderm
Headfold
Heart
heart mesoderm / lateral ectoderm lying half way between neural plate border and area pellucida border (prospective epidermis?) / head fold / excluded from midline and neural plate
7
stage 7
Head Mesenchyme
Neural Crest
Neural Plate/Tube
Trunk Mesenchyme
anterior neural plate / neural crest / epidermis of head / (epidermis of trunk?)
all
 
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.2351

Mouse

EmageMGI:104671
EurexpressMGI:104671
MGI GXDMGI:104671

Frog

Xenbase481200

Fruit Fly

BDGPFBgn0261953

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-011212-6
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