GEISHA - A Chicken Embryo Gene Expression Database
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POU4F3
POU class 4 homeobox 3

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolPOU4F3
Official Full NamePOU class 4 homeobox 3
CGNC ID49360
also known asBRN-3, BRN-3BRN3, BRN3, brain-specific homeobox/POU domain protein 3|POU domain, class 4, transcription factor 3|brain-3
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204759
PolypeptideNP_990090
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.282
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human5459ENSG00000091010MIM:602459MIM:602460
Mouse18998All phenotypic alleles (6):Spontaneous(1) Targeted, knock-out(4) Targeted, other(1) MGI:102523
Xenopus100498313853640
Zebrafish30534ENSDARG00000006206ZDB-GENE-990415-24ZFIN:ZDB-GENE-990415-24
Gene Ontology
Molecular Functionsequence-specific DNA binding, sequence-specific DNA binding transcription factor activity
Biological Processtranscription, DNA-templated
Cellular Componentnucleus
Links to other databases
Entrez Gene395521
Ensembl Gene
KEGGgga:395521

Entry 1

GEISHA IdBrn-3.Artinger.1998Data SourcePublication
Complete cDNA Template Probeshow
ATGATGTCCATGAACAGCAAGCAGGCTTTCAGCATGCACCCCATCCTGCACGAGCCCAAGTACCCCCACCTGCACACCA
GCTCCGAAGCCATCCGCAGAGCCTGCCTGCCCGCCCCCCAGATCCAGGGTAACATTTTTGCGGGCTTTGATGAGACCTT
GCTACGGGGCGCCGAGGCTCTGGCCGCTGTGGATATAGTATCGCAGAAAACCCATCCGTTCAAGCCGGATGCCACCTAC
CACACCATGAGCAGCGTGTCCTGCACTCCTACCTCGTCCTCTGTGCACCTGCACCACCCGTCCGTGCTGACCACCCACC
ACCCCCACCACCACCACCATCAGCCCGCGCAGGGCCTGGAGGGAGAGCTCCTGGACCACCTCAACTCTGCCCTCCCCCT
GGGAGGGGTGCCGGGTCCCGACGTGGGCTCCACGCCGTCCCACCCTCATTCCCACATGTCGGCCATTAACCACATGGCC
CACCACTCCCAACCTATGAACATGTCCCACCCCCACGGCCTGGCGTCCCACGCCGTCATCTCGGGCCCCGAGACAGAGA
CGGACCCACGGGAGCTGGAGTCCTTCGCCGAGCGCTTCAAGCAGCGGAGGATCAAGCTGGGGGTCACCCAGGCAGATGT
TGGATCTGCGTTGGCCAACCTGAAGATCCCGGGGGTGGGCTGCCTTAGCCAAAGCACAATCTGTAGGTTCGAGTCTCTC
ACCTTGTCCCACAACAACATGGTGGCCCTCAAACCCATTTTAGAAGCCTGGCTGGAGGAGGCCGAGCGGGCCCAGAGGG
AGAAAATGACCAAACCGGAGATCTACACGGGAGGTGACAAGAAACGCAAGCGCACCTCCATCGCTGCTCCCGAAAAGCG
CTCGCTGGAGGCTTACTTTGCCGTGCAGCCACGGCCCTCCTCGGAGAAAATCGCCGCCATCGCCGAGAAGTTAGACTTG
AAGAAGAACGTGGTGAGGGTCTGGTTTTGCAATCAGAGACAGAAGCAGAAAAGGATGAAATTTTCTGCCACTTACTGAA
GATGGGGCTGGGAAGGCGGCGGGGGCAGTGCCTGGCTCTCCGGCTGACGTGGCCCCCGGCCCCCCCCCCAGCCAATATT
CCCCCCAGAACTGGGCAGGGTTTGGGTTGATTTTTTTTGTTTGTTTTGTTTTGTGC
CitationArtinger KB, Fedtsova N, Rhee JM, Bronner-Fraser M, Turner E. Placodal origin of Brn-3-expressing cranial sensory neurons. J Neurobiol. 1998 Sep 15
CopyrightJournal of Neurobiology. Copyright © 1998 Wiley Periodicals, Inc., A Wiley Company.
CommentsA POU class transcription factor. Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_204759).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 15
stage 17
Cranial Ganglion
 
19-22
stage 21
stage 22
Cranial Ganglion
Midbrain
Spinal Ganglia and Nerves
Dorsal Root Ganglia
Tectum

Entry 2

GEISHA IdBRN3A.Thompson.2010Data SourcePublication
Complete cDNA Template Probeshow
GGTGACCCAGGCCGACGTGGGCTCGGCGCTGGCCAACCTGAAGATCCCGGGCGTGGGCTCGCTCAGCCAGAGCACCATC
TGCCGCTTCGAGTCGCTGACGCTGTCGCACAACAACATGATCGCCCTCAAGCCCATCCTGCAGGCCTGGCTGGAGGAGG
CCGAGGGGGCCCAGCGGGAAAAAATGAACAAGCCCGAGCTCTTCAACGGGGGCGAGAAGAAACGCAAGCGGACTTCCAT
CGCCGCCCCGGAGAAGCGCTCCCTGGAGGCGTACTTCGCCGTCCAGCCCCGGCCCTCCTCCGAGAAGATCGCTGCCATC
GCCGAGAAATTGGACCTCAAAAAGAACGTGGTGC
CitationThompson H, Blentic A, Watson S, Begbie J, Graham A. The formation of the superior and jugular ganglia: insights into the generation of sensory neurons by the neural crest. Dev Dyn. 2010 Feb;239(2):439-45.
CopyrightCopyright © 2010 John Wiley & Sons, Inc. All Rights Reserved.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #U77642).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-26
stage 26
stage 26
Spinal Ganglia and Nerves
 

Entry 3

GEISHA IdBRN3A/POU4F1.Agarwala.2002Data SourcePublication
Complete cDNA Template Probeshow
GGTGACCCAGGCCGACGTGGGCTCGGCGCTGGCCAACCTGAAGATCCCGGGCGTGGGCTCGCTCAGCCAGAGCACCATC
TGCCGCTTCGAGTCGCTGACGCTGTCGCACAACAACATGATCGCCCTCAAGCCCATCCTGCAGGCCTGGCTGGAGGAGG
CCGAGGGGGCCCAGCGGGAAAAAATGAACAAGCCCGAGCTCTTCAACGGGGGCGAGAAGAAACGCAAGCGGACTTCCAT
CGCCGCCCCGGAGAAGCGCTCCCTGGAGGCGTACTTCGCCGTCCAGCCCCGGCCCTCCTCCGAGAAGATCGCTGCCATC
GCCGAGAAATTGGACCTCAAAAAGAACGTGGTGC
CitationAgarwala S, Ragsdale CW. A role for midbrain arcs in nucleogenesis. Development. 2002 Dec;129(24):5779-88.
CopyrightPublished by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Permission granted by Dr. Ragsdale.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #U77642.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
1-3
stage 1
  
25-26
stage 26
stage 26
Midbrain
anatomy?
anatomy?
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.282

Mouse

EmageMGI:102523
EurexpressMGI:102523
MGI GXDMGI:102523

Frog

Xenbase853640

Fruit Fly

BDGP

Zebra Finch

ZEBrAPOU4F3

Zebrafish

ZFINZDB-GENE-990415-24
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