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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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POU4F3
POU class 4 homeobox 3

The human orthologue of this gene is associated
with the following human disease:

Deafness, autosomal dominant 15

Gene

Official Symbol	POU4F3
Official Full Name	POU class 4 homeobox 3
CGNC ID	49360
also known as	BRN-3, BRN-3BRN3, BRN3, brain-specific homeobox/POU domain protein 3\|POU domain, class 4, transcription factor 3\|brain-3
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204759
Polypeptide	NP_990090

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	5459	ENSG00000091010	MIM:602459	MIM:602460
Mouse	18998		All phenotypic alleles (6):Spontaneous(1) Targeted, knock-out(4) Targeted, other(1)	MGI:102523
Xenopus	100498313			853640
Zebrafish	30534	ENSDARG00000006206	ZDB-GENE-990415-24	ZFIN:ZDB-GENE-990415-24

Gene Ontology

Molecular Function	sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity
Biological Process	transcription, DNA-templated
Cellular Component	nucleus

Links to other databases

Entrez Gene	395521
Ensembl Gene
KEGG	gga:395521

Entry 1

GEISHA Id	Brn-3.Artinger.1998	Data Source	Publication
Complete cDNA Template Probe	show ATGATGTCCATGAACAGCAAGCAGGCTTTCAGCATGCACCCCATCCTGCACGAGCCCAAGTACCCCCACCTGCACACCA GCTCCGAAGCCATCCGCAGAGCCTGCCTGCCCGCCCCCCAGATCCAGGGTAACATTTTTGCGGGCTTTGATGAGACCTT GCTACGGGGCGCCGAGGCTCTGGCCGCTGTGGATATAGTATCGCAGAAAACCCATCCGTTCAAGCCGGATGCCACCTAC CACACCATGAGCAGCGTGTCCTGCACTCCTACCTCGTCCTCTGTGCACCTGCACCACCCGTCCGTGCTGACCACCCACC ACCCCCACCACCACCACCATCAGCCCGCGCAGGGCCTGGAGGGAGAGCTCCTGGACCACCTCAACTCTGCCCTCCCCCT GGGAGGGGTGCCGGGTCCCGACGTGGGCTCCACGCCGTCCCACCCTCATTCCCACATGTCGGCCATTAACCACATGGCC CACCACTCCCAACCTATGAACATGTCCCACCCCCACGGCCTGGCGTCCCACGCCGTCATCTCGGGCCCCGAGACAGAGA CGGACCCACGGGAGCTGGAGTCCTTCGCCGAGCGCTTCAAGCAGCGGAGGATCAAGCTGGGGGTCACCCAGGCAGATGT TGGATCTGCGTTGGCCAACCTGAAGATCCCGGGGGTGGGCTGCCTTAGCCAAAGCACAATCTGTAGGTTCGAGTCTCTC ACCTTGTCCCACAACAACATGGTGGCCCTCAAACCCATTTTAGAAGCCTGGCTGGAGGAGGCCGAGCGGGCCCAGAGGG AGAAAATGACCAAACCGGAGATCTACACGGGAGGTGACAAGAAACGCAAGCGCACCTCCATCGCTGCTCCCGAAAAGCG CTCGCTGGAGGCTTACTTTGCCGTGCAGCCACGGCCCTCCTCGGAGAAAATCGCCGCCATCGCCGAGAAGTTAGACTTG AAGAAGAACGTGGTGAGGGTCTGGTTTTGCAATCAGAGACAGAAGCAGAAAAGGATGAAATTTTCTGCCACTTACTGAA GATGGGGCTGGGAAGGCGGCGGGGGCAGTGCCTGGCTCTCCGGCTGACGTGGCCCCCGGCCCCCCCCCCAGCCAATATT CCCCCCAGAACTGGGCAGGGTTTGGGTTGATTTTTTTTGTTTGTTTTGTTTTGTGC
Citation	Artinger KB, Fedtsova N, Rhee JM, Bronner-Fraser M, Turner E. Placodal origin of Brn-3-expressing cranial sensory neurons. J Neurobiol. 1998 Sep 15
Copyright	Journal of Neurobiology. Copyright © 1998 Wiley Periodicals, Inc., A Wiley Company.
Comments	A POU class transcription factor. Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_204759).

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 15

stage 17

Cranial Ganglion

19-22

stage 21

stage 22

Cranial Ganglion
Midbrain
Spinal Ganglia and Nerves

Dorsal Root Ganglia
Tectum

Entry 2

GEISHA Id	BRN3A.Thompson.2010	Data Source	Publication
Complete cDNA Template Probe	show `GGTGACCCAGGCCGACGTGGGCTCGGCGCTGGCCAACCTGAAGATCCCGGGCGTGGGCTCGCTCAGCCAGAGCACCATC TGCCGCTTCGAGTCGCTGACGCTGTCGCACAACAACATGATCGCCCTCAAGCCCATCCTGCAGGCCTGGCTGGAGGAGG CCGAGGGGGCCCAGCGGGAAAAAATGAACAAGCCCGAGCTCTTCAACGGGGGCGAGAAGAAACGCAAGCGGACTTCCAT CGCCGCCCCGGAGAAGCGCTCCCTGGAGGCGTACTTCGCCGTCCAGCCCCGGCCCTCCTCCGAGAAGATCGCTGCCATC GCCGAGAAATTGGACCTCAAAAAGAACGTGGTGC`
Citation	Thompson H, Blentic A, Watson S, Begbie J, Graham A. The formation of the superior and jugular ganglia: insights into the generation of sensory neurons by the neural crest. Dev Dyn. 2010 Feb;239(2):439-45.
Copyright	Copyright © 2010 John Wiley & Sons, Inc. All Rights Reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #U77642).

Stage

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Location (click to highlight)

Comments (click to highlight)

25-26

stage 26

Spinal Ganglia and Nerves

Entry 3

GEISHA Id	BRN3A/POU4F1.Agarwala.2002	Data Source	Publication
Complete cDNA Template Probe	show `GGTGACCCAGGCCGACGTGGGCTCGGCGCTGGCCAACCTGAAGATCCCGGGCGTGGGCTCGCTCAGCCAGAGCACCATC TGCCGCTTCGAGTCGCTGACGCTGTCGCACAACAACATGATCGCCCTCAAGCCCATCCTGCAGGCCTGGCTGGAGGAGG CCGAGGGGGCCCAGCGGGAAAAAATGAACAAGCCCGAGCTCTTCAACGGGGGCGAGAAGAAACGCAAGCGGACTTCCAT CGCCGCCCCGGAGAAGCGCTCCCTGGAGGCGTACTTCGCCGTCCAGCCCCGGCCCTCCTCCGAGAAGATCGCTGCCATC GCCGAGAAATTGGACCTCAAAAAGAACGTGGTGC`
Citation	Agarwala S, Ragsdale CW. A role for midbrain arcs in nucleogenesis. Development. 2002 Dec;129(24):5779-88.
Copyright	Published by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Permission granted by Dr. Ragsdale.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #U77642.1).