GEISHA - A Chicken Embryo Gene Expression Database
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CHUK
conserved helix-loop-helix ubiquitous kinase

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolCHUK
Official Full Nameconserved helix-loop-helix ubiquitous kinase
CGNC ID52021
also known asinhibitor of nuclear factor kappa-B kinase subunit alpha|IKK-A|IKK-alpha|NFKBIKA|i kappa-B kinase alpha|ikBKA|ikappaB kinase|nuclear factor NF-kappa-B inhibitor kinase alpha
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001012904
PolypeptideNP_001012922
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.5483
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human1147ENSG00000213341MIM:613630MIM:600664
Mouse12675ENSMUSG00000025199All phenotypic alleles (11):Targeted, knock-out(4) Targeted, other(7) MGI:99484
Xenopus549654, 4445565910007
Zebrafish393287ENSDARG00000011662ZDB-GENE-040426-1069ZFIN:ZDB-GENE-040426-1069
Gene Ontology
Molecular FunctionATP binding, IkappaB kinase activity, protein heterodimerization activity, more...protein homodimerization activity
Biological Processactivation of innate immune response, activation of MAPK activity involved in innate immune response, more...activation of NF-kappaB-inducing kinase activity, cellular response to tumor necrosis factor, innate immune response, MyD88-dependent toll-like receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, toll-like receptor 15 signaling pathway, toll-like receptor 21 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 7 signaling pathway, toll-like receptor signaling pathway
Cellular Componentcytosol, nucleus, plasma membrane
Links to other databases
Entrez Gene423669
Ensembl GeneENSGALG00000003289
KEGGgga:423669
GEISHA IdCHUK.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template Primer5’-ACTGTTCAGAGCCAAGACCG-3’
Reverse cDNA Template Primer5’-AATTAACCCTCACTAAAGGGCTGTGTTGAAGGCACAAGG-3’cDNA Template Length639
Complete cDNA Template Probeshow
ACTGTTCAGAGCCAAGACCGAGTTCTAAAGGAGCTCTTTGGCCATCTCAGCAAGCTCTTGGGCTGTAAGCAGAAGATCA
TTGACTTGCTTCCAAAGATTGAAGTGGCTCTAAATAACATCAAAGAAGCTGATAACTCGGAGATGCAGATGCAAGGCAA
AAGACAAAGGGAGATATGGCATTTGCTGAAAATTGCTTGCACTCAGAGCTCTTCTCGTTCACTGGTAAGCTCCAGCCTA
GAAGGGACAGCCTCAACTCCTGCAGCCACGTGGGTCCCCCAGAGCTCCTCAGAATATGCACCTCACCCTCTTTCATCTA
TGGCAACTCCTGGAGATGGAGAAAACTTTGTTGATGTGATAGAGGAGAACCTGAATTATCTTGATCGCTTTAGCAGTAT
GTTGCAGGAGGCAAGAGAAGAGCAGAATAACAGCTTGACGAACTTCGACTGGAGCTGGCTGAAGTAGGCCCAGGAGCTG
TACTGCTTCCTGCCTGTGTGCAGACAGCTGGCTGCAGCCCCACGCTGTGTGCCCCATCACGTCTTGGTTTGGACATGTG
GATTGCCAAGGCTGCGGGGCCAGCAGCAGATATATGAAACTGGCACTGTTTTACGGACTGTGGCCTCCTTGTGCCTTCA
ACACAGC
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 10
stage 11
Unlabeled
 
13-18
stage 16
stage 18
Head Mesenchyme
Pharyngeal Arches and Clefts
 
19-24
stage 20
stage 22
Foregut
Head Mesenchyme
Leg Mesenchyme
Neural Plate/Tube
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Wing Mesenchyme
 
25-27
stage 27
stage 27
Foregut
Head Mesenchyme
Heart
Leg Mesenchyme
Lung
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Wing Mesenchyme
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.5483

Mouse

EmageMGI:99484
EurexpressMGI:99484
MGI GXDMGI:99484

Frog

Xenbase5910007

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040426-1069
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