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CYP26A1 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol CYP26A1 Official Full Name cytochrome P450 family 26 subfamily A member 1 CGNC ID 5082 also known as CYP26A, cytochrome P450 26A1|cytochrome P450, family 26, subfamily A, polypeptide 1|retinoic acid-degrading enzyme CYP26, Retinoic acid-degrading enzyme CYP26, Cytochrome P450 26A1 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Links to other databases
Entry 1 GEISHA Id Cyp26A1.Reijntjes.2004 Data Source Publication Complete cDNA Template Probe show ATGGGCTTCTCCGCTCTGGTCGCCAGCGCCCTGTGCACCTTCCTGCTGCCCCTGCTGCTCTTCCTGGCCGCCGTCCGGC
Citation Reijntjes S, Gale E, Maden M. Generating gradients of retinoic acid in the chick embryo: Cyp26C1 expression and a comparative analysis of the Cyp26 enzymes. Dev Dyn. 2004 Jul;230(3):509-17. Copyright Wiley-Liss, Inc. 2004 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_001001129).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 4-6
stage 6
stage 6
Neural Plate/Tube
Entry 2 GEISHA Id Cyp26A1.Maden.2007 Data Source Publication Complete cDNA Template Probe show ATGGGCTTCTCCGCTCTGGTCGCCAGCGCCCTGTGCACCTTCCTGCTGCCCCTGCTGCTCTTCCTGGCCGCCGTCCGGC
Citation Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A. (2007). Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo. Int J Dev Biol. 2007;51(3):191-200. Copyright "Reprinted from Int. J. Dev. Biol., 51, Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A, Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo, 191-200, Copyright (2007), with permission from Copyright © 2007 UBC Press". All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_001001129). Images are quail, but sequence and map shown are chick.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 18
Eye 31-44 stage 44
Eye Nasal Placcode/Nerve
Entry 3 GEISHA Id Cyp26A1.Albazerchi.2007 Data Source Publication Complete cDNA Template Probe show ATGGGCTTCTCCGCTCTGGTCGCCAGCGCCCTGTGCACCTTCCTGCTGCCCCTGCTGCTCTTCCTGGCCGCCGTCCGGC
Citation Albazerchi A, Stern CD. A role for the hypoblast (AVE) in the initiation of neural induction, independent of its ability to position the primitive streak. Dev Biol. 2007 Jan 15;301(2):489-503. Copyright Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_001001129.1).
Normal expression in the embryo proper plus induced expression to the right where the graft (*) has been placed.
Entry 4 GEISHA Id Cyp26.Rodriguez-Guzman.2007 Data Source Publication Complete cDNA Template Probe show TACGGCTTCATCTACAAGACTCACCTCTTTGGGCGGCCCACTGTGCGGGTGATGGGCGCTGAGAATGTGCGGCACATCC
Citation Rodriguez-Guzman m, Montero JA, Santesterban E, Gañan Y, Macias D, Hurle JM. Tendon-muscle crosstalk controls muscle bellies morphogenesis, which is mediated by cell death and retinoic acid signaling. Dev Biol. 2007 Feb 1;302(1):267-80. Copyright Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. Comments The authors said the probe was created by PCR using these primers: 5′-TACGGCTTCATCTACAAGACG-3′ and 5′-AATCTTGCAGGGAGATTGTCC-3 for retinoic acid hydrolase or cytochrome P450 family 26b type A1 (CYP26A1). The sequence here was extracted from NM_001001129.1 using these primer sequences.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-32 stage 32
Leg Mesenchyme
Entry 5 GEISHA Id Cyp26A1.Blentic.2003 Data Source Publication Complete cDNA Template Probe show ATGGGCTTCTCCGCTCTGGTCGCCAGCGCCCTGTGCACCTTCCTGCTGCCCCTGCTGCTCTTCCTGGCCGCCGTCCGGC
Citation Blentic A, Gale E, Maden M. Retinoic acid signalling centres in the avian embryo identified by sites of expression of synthesising and catabolising enzymes. Dev Dyn. 2003 May;227(1):114-27. Copyright Copyright © 2003 John Wiley & Sons, Inc. All Rights Reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_001001129).
Entry 6 GEISHA Id CYP26A1.Bayha.2009 Data Source Publication Complete cDNA Template Probe show ATGGGCTTCTCCGCTCTGGTCGCCAGCGCCCTGTGCACCTTCCTGCTGCCCCTGCTGCTCTTCCTGGCCGCCGTCCGGC
Citation Bayha E, Jørgensen MC, Serup P, Grapin-Botton A. Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis. PLoS One. 2009 Jun 10;4(6):e5845. Copyright http://creativecommons.org/licenses/by/2.5/ Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_001001129)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 4-6 stage 4
stage 4
stage 4
Epiblast 7-10 stage 10
stage 10
Endoderm
Entry 7 GEISHA Id CYP26A1.Tenin.2010 Data Source Publication Complete cDNA Template Probe show GTGCCTCCCGGCGGCCGGCTCCGTGCCGCCGCGACGGGGCACGTCTCCGCCTGGGCGCTGCCGGTCCCCGAGGAGCGCG
Citation Tenin G, Wright D, Ferjentsik Z, Bone R, McGrew MJ, Maroto M. The chick somitogenesis oscillator is arrested before all paraxial mesoderm is segmented into somites. BMC Dev Biol. 2010 Feb 25;10:24. Copyright authors retain copyright of their article, and grant any third party the right to use reproduce and disseminate the article, subject to the terms of BMC Developmental Biology copyright and license agreement Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NC_006093.3
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 20
stage 21
stage 22
stage 23
stage 24
Tail
Entry 8 GEISHA Id CYP26A1.Wilson.2007 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show ATGGGCTTCTCCGCTCTGGTCGCCAGCGCCCTGTGCACCTTCCTGCTGCCCCTGCTGCTCTTCCTGGCCGCCGTCCGGC
Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_001001129
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 21
Hindbrain Rhombomeres 25-30 stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
stage 29
Hindbrain Midbrain 31-34 stage 34
stage 34
Midbrain
Entry 9 GEISHA Id CYP26A1.Reijntjes.2010 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show GCCTCTCCAACCTTCACAACGGGCAGCACAAACACCGCAAAAAGGTGATCATGCAGGCCTTCTCCCGGGATGCCCTGCA
Citation Reijntjes S, Francis-West P, Mankoo BS. Retinoic acid is both necessary for and inhibits myogenic commitment and differentiation in the chick limb. Int J Dev Biol. 2010;54(1):125-34 Copyright © 2009 UBC Press Comments The complete cDNA template sequence was obtained from the information provided in the publication as described in Reijntjes et al. 2010.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 25
Wing AER 31-44 stage 44
Data from NCBI Unigene EST ProfileGga.331
Mouse Frog Fruit Fly Zebra Finch Zebrafish
