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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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SERPINE2
serpin family E member 2

Gene

Official Symbol	SERPINE2
Official Full Name	serpin family E member 2
CGNC ID	3824
also known as	glia-derived nexin\|plasminogen activator inhibitor type 1, member 2\|serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2\|serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2, Glia-derived nexin precursor (GDN) , Protease nexin I, PN-1, Protease inhibitor 7
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001083920
Polypeptide	NP_001077389
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4105

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	5270	ENSG00000135919		MIM:177010
Mouse	20720	ENSMUSG00000026249	All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2)	MGI:101780
Xenopus	394528, 446824			947566
Zebrafish	393153	ENSDARG00000029353	ZDB-GENE-040426-848	ZFIN:ZDB-GENE-040426-848

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	424805
Ensembl Gene	ENSGALG00000005135
KEGG	gga:424805

Entry 1

GEISHA Id	ChEST716m2	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show CTCTAGATCGCGACTGGAGATTATATTTTTTATTTATTGGCCGTTCATAATGCAGTTTATATTTTTTTTCCATTGTACA AAAACAAATATAAAATTTAAATCCAATAAAAAGTGTATACTAACAACCGATCAGTGACGAATTTACAATACATTAATAA AGGACAACGACGATGTGTATCTAACATCACATTAGGTTTTAAAACTCTCAGTGATACATGCACTATAAAAAATAAAAAC TGCTGAGAACTTTTAATCTAACACTACCAAGAACACCCAGGTATCAAAATACTCAAGAACCATAAGATAATCTTGATGG GGGTATCTACAAATTACACCTTTTCCACACCCAAAAAGAAACCAACATTAAAATAAATGTTTAACATTCTCTGTTAAAA TCCTCTCACAAAAGCCATACGTAAAATTCTTAGTAGATACAGAAAAAGCTCAAAAGTTTGTTAGCATGGGTAACCATTC AGTAATTCACACAATCTTTTAAACATTTCAAAGGCATACTGTAATTTTCCATCTGTATTTTTCCCCAAAAAGCCAGAAC TACGTTGACTCCCATTTCAAAACCTAGTCAGTGGTTAACACTAGCTCTTGAGTGAAGTCAGAGTAGCATACAAAATATT GAACAGAACAGGGGTGTGGCACATGAGTCTGTTTACTTCTTGAAGAAAGTCTTCCACATTCAACGTTTGTTTATTTGTC CCATAAACAAGATTGTACCTGTAGGATTGTGCCCGATGATGAATACAAATGGTCTGTCTACTATGAAC
Comments	No specific expression detected for stages 6-21.

Stage

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Location (click to highlight)

Comments (click to highlight)

stage 4

Primitive Streak

Entry 2

GEISHA Id	SERPINE2.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	5’-AAAGGACCCTCTGAAAGCCC-3’
Reverse cDNA Template Primer	5’-AATTAACCCTCACTAAAGGACATTAAGACAGGACAACGCG-3’	cDNA Template Length	822
Complete cDNA Template Probe	show AAAGGACCCTCTGAAAGCCCTTGGTATTACAGATATGTTTGATGAGTCAAAATCAAACTTTGCAAAAATAACAAGAACA GAAGGTCTACACGTATCTCATGTTTTGCAGAAGACGAAAATTGAAGTTAGTGAAGATGGAACCAAAGCTTCTGCAGCAA CAACTGCGATTTTAATAGCCAGATCATCCCCTCCTTGGTTCATAGTAGACAGACCATTTGTATTCTTCATCCGGCACAA TCCTACAGGTACAATCTTGTTTATGGGACAAATAAACAAACCTTGAATGTGGAAGACTTTCTTCAAGAAGTAAACAGAC TCATGTGCCACACCCCTGTTCTGTTCAATATTTTGTATGCTACTCTGACTTCACTCAAGAGCTAGTGTTAACCACTGAC TAGGTTTTGAAATGGGAGTCAACGTAGTTCTGGCTTTTTGGGGAAAAATACAGATGGAAAACTACAGTATGCCTTTGAA ATGTCTAAAAGATTCTCTGAACTACTGAATGGTTACCCATGCTAACAAACTTTTGAGCTTTTTCTGTATCTACTAAGAA TTTTACGTATGGCTTTTGTGAGAGGATTTTAACAGAGAATGTTAAACATTTCTATTAATGTTGGTTTCTTCTTGTGTGT GGAAAAGGTCTAATTTGTAGATACCCCCATCAAGATTACTTCTGGTTCTTGAGTATCTTGATACCTGGGTGTTCTTGGT AGAGATAGATTAAAAGTTCTAGCAGTTTTTATTTTATATAGTGCATGTATCACTGAGAGTTTTAAAACTAATGTGATGT TAGATACACATCGCGTTGTCCTGTCTTAATGT

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 5

Early Mesoderm
Epiblast
Hensen's Node
Primitive Streak

7-12

stage 8

stage 10

stage 12

Area Opaca
Blood Islands
Eye
Forebrain
Head Mesenchyme
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Crest
Neural Plate/Tube
Notochord
Sinus Venosus
Somites
Ventricles

13-18

stage 16

Foregut
Head Mesenchyme
Leg Mesenchyme
Neural Plate/Tube
Notochord
Outflow Tract
Pharyngeal Arches and Clefts
Sinus Venosus
Somites
Tail
Ventricles
Widespread Expression
Wing Mesenchyme

19-24

stage 19

stage 22

stage 23

Foregut
Head Mesenchyme
Hindbrain
Leg Mesenchyme
Liver
Lung
Mesonephros
Neural Plate/Tube
Pharyngeal Arches and Clefts
Sclerotome
Widespread Expression
Wing Mesenchyme

stage 25

Blood Vessels
Foregut
Head Mesenchyme
Leg Mesenchyme
Lung
Notochord
Pharyngeal Arches and Clefts
Sclerotome
Sinus Venosus
Spinal Cord
Ventricles
Wing Mesenchyme

Entry 3

GEISHA Id	Pn-1.Rodríguez-Niedenführ.2003	Data Source	Publication
Complete cDNA Template Probe	show CGGGCGGCCGCGGCGGGAGCGGGGCCGAGAGCTGCGAGGGAGGTTATTTCCAACCAGAAACCATGAACTGGCACTTCTC GCTTCTCTTTCTTCTTGGGACTTTAGCATCTGTGTGTTCCCAGTTCAATTTTTATCCTCTGGAGGAGCTTAGCTCTGAT GTTGGAATCCAAGTCTTCAATCAGATAGTGAAAGCTAAGCCTCAGGACAATGTAGTAGTTTCTCCTCATGGGATTGCAT CAGTGTTGGGGGTGTTACAGCTGGGTGCTGATGGCAAGACAAAGAAGCAGCTGACAACTATGATGAGATATAGTGTAAA TGGAGCAGAAAACCCTCCAAGAGCAGCTGGAAGCAAGGAGGAGAGCCAGCATCATGAGACCAGCCAGCTCTCCCCGGAC CACCAGCAAGTGCTCCGTGGACCACCAGTGGTCCACAGAATACAGTTTGAGAACCTCTGTTATGGAGTTGGTAAAGCGT TAAAGAAGATAAACAGGCTCATAGTCTCAAAAAAGAATAAAGACATTGTTACAATTGCTAATGCAGTATTTGCAAAGAG TGGCTTTAAAATGGAAGTGCCTTTTGTTACAAGGAACAAAGAGGTGTTTCAGTGCAGTGTCAAGAGCGTGGACTTTGAG GACCCAAATACAGCCTGTGATTCCATCAACCAGTGGGTGAAAAATGAAACAAGGGGTATGATTGATCAAGTTGTAGCTC CAGATGATATTGACAGTTTAACCAGACTGGTTCTAGTAAATGCTGTGTATTTCAAGGGCTTGTGGAAATCACGATTTCG ACCTGAAAACACAAAGAAACGGCCATTTTATGGAGCTGATGGGAAGACCTACCAAGTTCCCATGTTGTCCCAGTTATCA ATCTTCCGCTGTGGTACTACAAGTACTCCAAATGAGCTGTGGTATAACATAATTGAATTGCCATACCATGGAGAAATGA TAAGCATGTTGATTGCTTTGCCTACGGAGAACACAACACCGCTCTCTGCTATCATTCCACACATCAGCACAAAGACAAT AGGAAGCTGGATGACAACCATGGTAGCCAAAAGAGTGCAGGTTATTTTGCCCAAATTTACAGCAGTAGCAGAAACAGAC TTAAAGGACCCTCTGAAAGCCCTTGGTATTACAGATATGTTTGATGAGTCAAAATCAAACTTTGCAAAAATAACAAGAA CAGAAGGTCTACACGTATCTCATGTTTTGCAGAAGACGAAAATTGAAGTTAGTGAAGATGGAACCAAAGCTTCTGCAGC AACAACTGCGATTTTAATAGCCAGATCATCCCCTCCTTGGTTCATAGTAGACAGACCATTTGTATTCTTCATCCGGCAC AATCCTACAGGTACAATCTTGTTTATGGGACAAATAAACAAACCTTGAATGTGGAAGACTTTCTTCAAGAAGTAAACAG ACTCATGTGCCACACCCCTGTTCTGTTCAATATTTTGTATGCTACTCTGACTTCACTCAAGAGCTAGTGTTAACCACTG ACTAGGTTTTGAAATGGGAGTCAACGTAGTTCTGGCTTTTTGGGGAAAAATACAGATGGAAAACTACAGTATGCCTTTG AAATGTCTAAAAGATTCTCTGAACTACTGAATGGTTACCCATGCTAACAAACTTTTGAGCTTTTTCTGTATCTACTAAG AATTTTACGTATGGCTTTTGTGAGAGGATTTTAACAGAGAATGTTAAACATTTCTATTAATGTTGGTTTCTTCTTGTGT GTGGAAAAGGTCTAATTTGTAGATACCCCCATCAAGATTACTTCTGGTTCTTGAGTATCTTGATACCTGGGTGTTCTTG GTAGAGATAGATTAAAAGTTCTAGCAGTTTTTATTTTATATAGTGCATGTATCACTGAGAGTTTTAAAACTAATGTGAT GTTAGATACACATCGCGTTGTCCTGTCTTAATGTAATGTAAACTTGTCATTGCTAGGTTGCTAGTATACACTTTCTATT GGATTTAAATTTTATATTTGTTTTTGTACAAAGGAAAAAAAATAAAACTGCATTATGAACAGTC
Citation	Rodríguez-Niedenführ M, Pröls F, Christ B. Temporal and spatial protease nexin 1 expression during chick development. Gene Expr Patterns. 2003 Oct;3(5):611-4.
Copyright	Reprinted from Gene Expression Patterns, Volume 3, Issue 5, M. Rodríguez-Niedenführ, F. Pröls and B. Christ, Temporal and spatial protease nexin 1 expression during chick development, Pages 611-614, Copyright 2003, with permission from Elsevier. Copyright © 2003 Elsevier B.V. All rights reserved.
Comments	According to the authors: The original 1392 bp clone was used as template. Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_001083920).