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EFNB2 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol EFNB2 Official Full Name ephrin B2 CGNC ID 49409 also known as ephrin-B2, ephrin-B2 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id EphrinB2.UAlinear Data Source GEISHA ISH Analysis Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Entry 2 GEISHA Id EphrinB2.Baker.2003 Data Source Publication Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Baker RK, Antin PB. Ephs and ephrins during early stages of chick embryogenesis Dev Dyn. 2003 Sep;228(1):128-42. Copyright 2003 Wiley-Liss, Inc.
Entry 3 GEISHA Id ephrin-B2.Mühleisen.2006 Data Source Publication Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Mühleisen TW, Agoston Z, Schulte D. Retroviral misexpression of cVax disturbs retinal ganglion cell axon fasciculation and intraretinal pathfinding in vivo and guidance of nasal ganglion cell axons in vivo. Dev Biol. 2006 Sep 1;297(1):59-73. Copyright Reprinted from Developmental Biology, Volume 297, Thomas W. Mühleisen, Zsuzsa Agoston and Dorothea Schulte, Retroviral misexpression of cVax disturbs retinal ganglion cell axon fasciculation and intaretinal pathfinding in vivo and guidance of nasal ganglion cell axons in vitro, Pages 56-73, Copyright 2006, with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights reserved. Comments According to the authors, "The cDNA clones used to generate in situ probes for EphA3, EphA4, ephrin-A5, ephrin-A2, EphB2, EphB3, ephrin-B1, ephrin-B2 or RCS, which recognizes a viral core protein, were described elsewhere (Schulte et al., 1999) or were gifts from J. Flanagan, C. Cepko (Harvard Medical School, Boston), or E. Pasquale (The Burnham Institute, La Jolla, California; Holash and Pasquale, 1995 and Cheng et al., 1995). As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204824)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 15
Eye Retina 19-20 stage 20
stage 20
Eye Retina
Entry 4 GEISHA Id EPHRIN-B2.Peters.2002 Data Source Publication Reverse cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Peters MA, Cepko CL (2002). The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments. Dev Biol. 2002 Nov 1;251(1):59-73. Copyright "Reprinted from Developmental Biology, 251(1), Peters MA, Cepko CL, The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments, 59-73, Copyright (2002), with permission from Elsevier". Copyright © ( 2002) Elsevier B.V. All rights reserved. Comments According to authors , "Probes for Pax2,
Bmp4, Tbx5, SOHo, ephrin-B1, ephrin-B2, EphB1-B3, ALDH3/ALDH6, and ALDH1 were prepared as described (Refs)." As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204824).
Entry 5 GEISHA Id EphrinB2.Davey.2007 Data Source Publication Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Davey MG, James J, Paton IR, Burt DW, Tickle C. Analysis of talpid3 and wild-type chicken embryos reveals roles fro Hedgehog signalling in development of the limb bud vasculature. Dev Biol. 2007 Jan 1;301(1):155-65. Copyright Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_204824.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25 stage 25
Arteries
Entry 6 GEISHA Id Ephrin-B2.Marin.2001 Data Source Publication Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Marín O, Blanco MJ, Nieto MA (2001). Differential expression of Eph receptors and ephrins correlates with the formation of topographic projections in primary and secondary visual circuits of the embryonic chick forebrain. Dev Biol. 2001 Jun 15;234(2):289-303. Copyright Copyright © 2001 Academic Press. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204824).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-35 stage 35
stage 35
Telencephalon
Entry 7 GEISHA Id EFNB2.Hardy.2011 Data Source Publication Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Hardy KM, Yatskievych TA, Konieczka J, Bobbs AS, Antin PB. FGF signalling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting E-cadherin expression. BMC Dev Biol. 2011 Mar 21;11:20.
Copyright © 2011 Hardy et al; licensee BioMed Central Ltd. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204824).
Entry 8 GEISHA Id EPHRINB2.Watanabe.2009 Data Source Publication Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Watanabe T, Sato Y, Saito D, Tadokoro R, Takahashi Y. EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation. Proc Natl Acad Sci U S A. 2009 May 5; 106(18): 74677472. Copyright Copyright 2009 national Academy of Sciences USA Comments The probe was amplified by PCR using the following primers:
5′-ATGGCAGCGCGGCGGCGCGACG-3′ and 5′-CTAGTAAATGTTTGCTGGACTCTGAGG-3′ and was extracted from NCBI Acc#NM_204824.1.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Paraxial Mesoderm
Entry 9 GEISHA Id EPHRINB2.Mellott.2008 Data Source Publication Complete cDNA Template Probe show ATGGCAGCGCGGCGGCGCGACGCCTCCGCCTGCAAGTACTGCTGGGGAGCCCTCATGGTTTTATGGAGAACTGCGCTGG
Citation Mellott DO, and Burke RD. Divergent roles for Eph and Ephrin in Avian Cranial Neural Crest. BMC Developmental Biology 2008, 8:56. Copyright © 2008 Mellott and Burke; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204824.1.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-14 stage 13
stage 14
stage 14
Head Mesenchyme Hindbrain
Entry 10 GEISHA Id EFNB2.Anderson.2020 Data Source Direct Submission Complete cDNA Template Probe show AATTCAGCCCTAATCTCTGGGGCCTGGAATTTCAGAAGAACAAAGATTATTACGTCATATCAACATCAAATGTGTCTTT
Comments Images and probe sequence provided by Claire Anderson.
Data from NCBI Unigene EST ProfileGga.357
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