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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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EMX2
empty spiracles homeobox 2

The human orthologue of this gene is associated
with the following human disease:

Schizencephaly

Gene

Official Symbol	EMX2
Official Full Name	empty spiracles homeobox 2
CGNC ID	7069
also known as	homeobox protein EMX2\|empty spiracles homolog 2, Homeobox protein EMX2 , Empty spiracles homolog 2, Empty spiracles- like protein 2
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	XM_421783
Polypeptide	XP_421783
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.50588

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	41697			FBgn0000576
Human	2018	ENSG00000170370	MIM:269160	MIM:600035
Mouse	13797	ENSMUSG00000043969	All phenotypic alleles (8):Chemically induced(2) Targeted, knock-out(2) Targeted, other(4)	MGI:95388
Xenopus	100038069, 444481			481027
Zebrafish	100334611, 30537	ENSDARG00000039701	ZDB-GENE-990415-54	ZFIN:ZDB-GENE-990415-54

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	423923
Ensembl Gene	ENSGALG00000009302
KEGG	gga:423923

Entry 1

GEISHA Id	Emx2.vonFrowein.2006	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show GCGGGGCACCGCGTTACACCCAGTCACTCCCCGCTGCAAACTTCCCCGGATCGCCTCCTCCCGCGCACCGCAGAGCCAC GCACAGATTTGCCGGGGGACGCCCGCCGCCGCCGCACCATGTTTCAGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTC GCTGGTGGCCAAAGACAGCCCCTTGCCCGCGTCTCGCTCCGAGGATCCCATCCGCCCGGCGGCTCTCAGCTATGCCAAT TCCAGCCCGATGAACCCTTTTCTCAACGGCTTCCACTCCACCGGCAGGGGGGTCTACTCCAACCCGGACTTGGTCTTTG CGGAGGCCGTCTCCCACCCGCCGAACCCGGCCGTGCCCGTGCACCCCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCC GCTGCCCGCCTCGCACTCCACGCACCCGCTCTTCGCTTCGCAGCAAAGGGATCCCTCCACCTTCTACCCGTGGCTAATA CACCGCTACCGGTATCTGGGCCACAGGTTCCAAGGGAACGAGACCAGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGG CCAGGAAACCCAAACGGATCCGTACAGCTTTCTCCCCGTCCCAATTACTGAGACTGGAACATGCCTTTGAGAAGAACCA TTATGTGGTGGGAGCGGAGAGAAAGCAGCTGGCACACAGCCTCAGCCTCACGGAAACTCAGGTAAAAGTATGGTTTCAG AACAGAAGGACAAAGTTCAAGCGGCAAAAGTTGGAAGAGGAAGGTTCGGACTCACAACAGAAGAAAAAAGGGACTCATC ACATTAACCGGTGGAGAATCGCCACCAAACAAGCCAGTCCAGAAGAAATCGACGTCACGTCGGACGATTAAAAACTGGC ACTTTGGGACTTTTCAAGCCAGCCAACGCATCGAGAGAAAGTGTTAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGG AAGGGACACGGAGAGCTTCATCCAAACGCGATTCCCGTCTGGAGGGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTG CGGAGCGCGGCGCTGCCGGCGCGGCCCTGGCACGGGGATCTGCCGGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTG ACTGACTGACTGACTGACAGGTGTTCCGTTTCTCGCAGTCCACTTTTAAAA
Comments	Plasmid templates were used to generate digoxygenin antisense riboprobes, Emx1, Emx2 (E. Bell) (Bell et al., 2001). Sequence below is from Bell.

Stage

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Location (click to highlight)

Comments (click to highlight)

19-22

stage 22

Forebrain

Entry 2

GEISHA Id	EMX2.Bell.2001	Data Source	Publication
Complete cDNA Template Probe	show ACATCCATGGATTGTCTTTGGACTTAGGGAGGGAGGGGGGGGCGGGGGGGGGCGACCGCCTTTTCCTCGCAGGAGGGAA ACTTCTCCCAGCAACTTTCCGCGTGTGTGTGTGTGTGTGCGCGGCGCGCGTGTCTCCCTTTTGGGTACCGCCGGCTGCC GCTGCCTCCTTCCCTCCGGCCCCCGTCTATTTATGTGTGTATCTATCCCTCCTCAAGTCACTCCCCGCTGCAAACTTCC CCGGATCGCCTCCTCCCGCGCACCGCAGAGCCACGCACAGATTTGCCGGGGGACGCCCGCCGCCGCCGCACCATGTTTC AGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTCGCTGGTGGCCAAAGACAGCCCCTTGCCCGCGTCTCGCTCCGAGGA TCCCATCCGCCCGGCGGCTCTCAGCTATGCCAATTCCAGCCCGATGAACCCTTTTCTCAACGGCTTCCACTCCACCGGC AGGGGGGTCTACTCCAACCCGGACTTGGTCTTTGCGGAGGCCGTCTCCCACCCGCCGAACCCGGCCGTGCCCGTGCACC CCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCCGCTGCCCGCCTCGCACTCCACGCACCCGCTCTTCGCTTCGCAGCA AAGGGATCCCTCCACCTTCTACCCGTGGCTAATACACCGCTACCGGTATCTGGGCCACAGGTTCCAAGGGAACGAGACC AGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGGCCAGGAAACCCAAACGGATCCGTACAGCTTTCTCCCCGTCCCAAT TACTGAGACTGGAACATGCCTTTGAGAAGAACCATTATGTGGTGGGAGCGGAGAGAAAGCAGCTGGCACACAGCCTCAG CCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACAGAAGGACAAAGTTCAAGCGGCAAAAGTTGGAAGAGGAAGGT TCGGACTCACAACAGAAGAAAAAAGGGACTCATCACATTAACCGGTGGAGAATCGCCACCAAACAAGCCAGTCCAGAAG AAATCGACGTCACGTCGGACGATTAAAAAACTGGCACTTTGGGACTTTTCAAGCCAGCCAACGCATCGAGAGAAAGTGT TAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGGAAGGGACACGGAGAGCTTCATCCAAACGCGATTCCCGTCTGGAG GGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTGCGGAGCGCGGCGCTGCCGGCGCGGCCCTGGCACGGGGATCTGCC GGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTGACTGACTGACTGACTGACAGGTATTCCGTTTCTCGCAGTCCACT TTTAAAAACATAACGTC
Citation	Bell E, Ensini M, Gulisano M, Lumsden A. Dynamic domains of gene expression in the early avian forebrain. Dev Biol. 2001 Aug 1;236(1):76-88.
Copyright	Copyright © 2001 Academic Press All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_421783).

Stage

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Location (click to highlight)

Comments (click to highlight)

7-12

stage 8

stage 9

stage 11

stage 12

Forebrain
Telencephalon

Dorsal Telencephalon
Prosencephalon

13-18

stage 13

Telencephalon

Dorsal Telencephalon
Expression patterns of qin, Emx1, Emx2, and Pax6 along the A-P axis of the prosencephalon during early development.

19-20

stage 19

stage 20

Telencephalon

Dorsal Telencephalon
Dorsal Telencephalon (pallium)
Expression of Emx2, Emx1, and qin at HH17 and HH19.
Expression of dorsal-expressed genes, Emx1, Emx2, Pax6 in relation to a ventral-expressed gene, Dlx2.

Entry 3

GEISHA Id	EMX2.Agarwala.2002	Data Source	Publication
Complete cDNA Template Probe	show ACATCCATGGATTGTCTTTGGACTTAGGGAGGGAGGGGGGGGCGGGGGGGGGCGACCGCCTTTTCCTCGCAGGAGGGAA ACTTCTCCCAGCAACTTTCCGCGTGTGTGTGTGTGTGTGCGCGGCGCGCGTGTCTCCCTTTTGGGTACCGCCGGCTGCC GCTGCCTCCTTCCCTCCGGCCCCCGTCTATTTATGTGTGTATCTATCCCTCCTCAAGTCACTCCCCGCTGCAAACTTCC CCGGATCGCCTCCTCCCGCGCACCGCAGAGCCACGCACAGATTTGCCGGGGGACGCCCGCCGCCGCCGCACCATGTTTC AGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTCGCTGGTGGCCAAAGACAGCCCCTTGCCCGCGTCTCGCTCCGAGGA TCCCATCCGCCCGGCGGCTCTCAGCTATGCCAATTCCAGCCCGATGAACCCTTTTCTCAACGGCTTCCACTCCACCGGC AGGGGGGTCTACTCCAACCCGGACTTGGTCTTTGCGGAGGCCGTCTCCCACCCGCCGAACCCGGCCGTGCCCGTGCACC CCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCCGCTGCCCGCCTCGCACTCCACGCACCCGCTCTTCGCTTCGCAGCA AAGGGATCCCTCCACCTTCTACCCGTGGCTAATACACCGCTACCGGTATCTGGGCCACAGGTTCCAAGGGAACGAGACC AGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGGCCAGGAAACCCAAACGGATCCGTACAGCTTTCTCCCCGTCCCAAT TACTGAGACTGGAACATGCCTTTGAGAAGAACCATTATGTGGTGGGAGCGGAGAGAAAGCAGCTGGCACACAGCCTCAG CCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACAGAAGGACAAAGTTCAAGCGGCAAAAGTTGGAAGAGGAAGGT TCGGACTCACAACAGAAGAAAAAAGGGACTCATCACATTAACCGGTGGAGAATCGCCACCAAACAAGCCAGTCCAGAAG AAATCGACGTCACGTCGGACGATTAAAAAACTGGCACTTTGGGACTTTTCAAGCCAGCCAACGCATCGAGAGAAAGTGT TAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGGAAGGGACACGGAGAGCTTCATCCAAACGCGATTCCCGTCTGGAG GGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTGCGGAGCGCGGCGCTGCCGGCGCGGCCCTGGCACGGGGATCTGCC GGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTGACTGACTGACTGACTGACAGGTATTCCGTTTCTCGCAGTCCACT TTTAAAAACATAACGTC
Citation	Agarwala S, Ragsdale CW. A role for midbrain arcs in nucleogenesis. Development. 2002 Dec;129(24):5779-88.
Copyright	Published by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Permission granted by Dr. Ragsdale.
Comments	XM_421783.2

Stage

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Location (click to highlight)

Comments (click to highlight)

25-26

stage 26

Midbrain

double label
double labeled
normal on left

Entry 4

GEISHA Id	EMX2.Halilagic.2007	Data Source	Publication
Complete cDNA Template Probe	show ACATCCATGGATTGTCTTTGGACTTAGGGAGGGAGGGGGGGGCGGGGGGGGGCGACCGCCTTTTCCTCGCAGGAGGGAA ACTTCTCCCAGCAACTTTCCGCGTGTGTGTGTGTGTGTGCGCGGCGCGCGTGTCTCCCTTTTGGGTACCGCCGGCTGCC GCTGCCTCCTTCCCTCCGGCCCCCGTCTATTTATGTGTGTATCTATCCCTCCTCAAGTCACTCCCCGCTGCAAACTTCC CCGGATCGCCTCCTCCCGCGCACCGCAGAGCCACGCACAGATTTGCCGGGGGACGCCCGCCGCCGCCGCACCATGTTTC AGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTCGCTGGTGGCCAAAGACAGCCCCTTGCCCGCGTCTCGCTCCGAGGA TCCCATCCGCCCGGCGGCTCTCAGCTATGCCAATTCCAGCCCGATGAACCCTTTTCTCAACGGCTTCCACTCCACCGGC AGGGGGGTCTACTCCAACCCGGACTTGGTCTTTGCGGAGGCCGTCTCCCACCCGCCGAACCCGGCCGTGCCCGTGCACC CCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCCGCTGCCCGCCTCGCACTCCACGCACCCGCTCTTCGCTTCGCAGCA AAGGGATCCCTCCACCTTCTACCCGTGGCTAATACACCGCTACCGGTATCTGGGCCACAGGTTCCAAGGGAACGAGACC AGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGGCCAGGAAACCCAAACGGATCCGTACAGCTTTCTCCCCGTCCCAAT TACTGAGACTGGAACATGCCTTTGAGAAGAACCATTATGTGGTGGGAGCGGAGAGAAAGCAGCTGGCACACAGCCTCAG CCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACAGAAGGACAAAGTTCAAGCGGCAAAAGTTGGAAGAGGAAGGT TCGGACTCACAACAGAAGAAAAAAGGGACTCATCACATTAACCGGTGGAGAATCGCCACCAAACAAGCCAGTCCAGAAG AAATCGACGTCACGTCGGACGATTAAAAAACTGGCACTTTGGGACTTTTCAAGCCAGCCAACGCATCGAGAGAAAGTGT TAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGGAAGGGACACGGAGAGCTTCATCCAAACGCGATTCCCGTCTGGAG GGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTGCGGAGCGCGGCGCTGCCGGCGCGGCCCTGGCACGGGGATCTGCC GGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTGACTGACTGACTGACTGACAGGTATTCCGTTTCTCGCAGTCCACT TTTAAAAACATAACGTC
Citation	Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M. Retinoids control anterior and dorsal properties in the developing forebrain. Dev Bio 2007 Mar 1;303(1):244-58
Copyright	Reprinted with permission from Elsevier. Copyright © 2007 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # XM_421783.2). Images are quail, but sequence and map shown are chick.

Stage

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Location (click to highlight)

Comments (click to highlight)

stage 19

Eye
Telencephalon

Entry 5

GEISHA Id	EMX2.Schubert.2005	Data Source	Publication
Complete cDNA Template Probe	show ACATCCATGGATTGTCTTTGGACTTAGGGAGGGAGGGGGGGGCGGGGGGGGGCGACCGCCTTTTCCTCGCAGGAGGGAA ACTTCTCCCAGCAACTTTCCGCGTGTGTGTGTGTGTGTGCGCGGCGCGCGTGTCTCCCTTTTGGGTACCGCCGGCTGCC GCTGCCTCCTTCCCTCCGGCCCCCGTCTATTTATGTGTGTATCTATCCCTCCTCAAGTCACTCCCCGCTGCAAACTTCC CCGGATCGCCTCCTCCCGCGCACCGCAGAGCCACGCACAGATTTGCCGGGGGACGCCCGCCGCCGCCGCACCATGTTTC AGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTCGCTGGTGGCCAAAGACAGCCCCTTGCCCGCGTCTCGCTCCGAGGA TCCCATCCGCCCGGCGGCTCTCAGCTATGCCAATTCCAGCCCGATGAACCCTTTTCTCAACGGCTTCCACTCCACCGGC AGGGGGGTCTACTCCAACCCGGACTTGGTCTTTGCGGAGGCCGTCTCCCACCCGCCGAACCCGGCCGTGCCCGTGCACC CCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCCGCTGCCCGCCTCGCACTCCACGCACCCGCTCTTCGCTTCGCAGCA AAGGGATCCCTCCACCTTCTACCCGTGGCTAATACACCGCTACCGGTATCTGGGCCACAGGTTCCAAGGGAACGAGACC AGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGGCCAGGAAACCCAAACGGATCCGTACAGCTTTCTCCCCGTCCCAAT TACTGAGACTGGAACATGCCTTTGAGAAGAACCATTATGTGGTGGGAGCGGAGAGAAAGCAGCTGGCACACAGCCTCAG CCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACAGAAGGACAAAGTTCAAGCGGCAAAAGTTGGAAGAGGAAGGT TCGGACTCACAACAGAAGAAAAAAGGGACTCATCACATTAACCGGTGGAGAATCGCCACCAAACAAGCCAGTCCAGAAG AAATCGACGTCACGTCGGACGATTAAAAAACTGGCACTTTGGGACTTTTCAAGCCAGCCAACGCATCGAGAGAAAGTGT TAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGGAAGGGACACGGAGAGCTTCATCCAAACGCGATTCCCGTCTGGAG GGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTGCGGAGCGCGGCGCTGCCGGCGCGGCCCTGGCACGGGGATCTGCC GGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTGACTGACTGACTGACTGACAGGTATTCCGTTTCTCGCAGTCCACT TTTAAAAACATAACGTC
Citation	Schubert FR, Lumsden A. Transcriptional control of early tract formation in the embryonic chick midbrain. Development. 2005 Apr;132(8):1785-93. Epub 2005 Mar 16.
Copyright	copyright 2005 by the authors. Published by the Company of Biologists Ltd.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #XM_421783.2 ).

Stage

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Location (click to highlight)

Comments (click to highlight)

19-24

stage 20

Midbrain
Pharyngeal Arches and Clefts

stage 25

Midbrain

Entry 6

GEISHA Id	EMX2.Frowein.2002	Data Source	Publication
Complete cDNA Template Probe	show ACATCCATGGATTGTCTTTGGACTTAGGGAGGGAGGGGGGGGCGGGGGGGGGCGACCGCCTTTTCCTCGCAGGAGGGAA ACTTCTCCCAGCAACTTTCCGCGTGTGTGTGTGTGTGTGCGCGGCGCGCGTGTCTCCCTTTTGGGTACCGCCGGCTGCC GCTGCCTCCTTCCCTCCGGCCCCCGTCTATTTATGTGTGTATCTATCCCTCCTCAAGTCACTCCCCGCTGCAAACTTCC CCGGATCGCCTCCTCCCGCGCACCGCAGAGCCACGCACAGATTTGCCGGGGGACGCCCGCCGCCGCCGCACCATGTTTC AGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTCGCTGGTGGCCAAAGACAGCCCCTTGCCCGCGTCTCGCTCCGAGGA TCCCATCCGCCCGGCGGCTCTCAGCTATGCCAATTCCAGCCCGATGAACCCTTTTCTCAACGGCTTCCACTCCACCGGC AGGGGGGTCTACTCCAACCCGGACTTGGTCTTTGCGGAGGCCGTCTCCCACCCGCCGAACCCGGCCGTGCCCGTGCACC CCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCCGCTGCCCGCCTCGCACTCCACGCACCCGCTCTTCGCTTCGCAGCA AAGGGATCCCTCCACCTTCTACCCGTGGCTAATACACCGCTACCGGTATCTGGGCCACAGGTTCCAAGGGAACGAGACC AGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGGCCAGGAAACCCAAACGGATCCGTACAGCTTTCTCCCCGTCCCAAT TACTGAGACTGGAACATGCCTTTGAGAAGAACCATTATGTGGTGGGAGCGGAGAGAAAGCAGCTGGCACACAGCCTCAG CCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACAGAAGGACAAAGTTCAAGCGGCAAAAGTTGGAAGAGGAAGGT TCGGACTCACAACAGAAGAAAAAAGGGACTCATCACATTAACCGGTGGAGAATCGCCACCAAACAAGCCAGTCCAGAAG AAATCGACGTCACGTCGGACGATTAAAAAACTGGCACTTTGGGACTTTTCAAGCCAGCCAACGCATCGAGAGAAAGTGT TAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGGAAGGGACACGGAGAGCTTCATCCAAACGCGATTCCCGTCTGGAG GGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTGCGGAGCGCGGCGCTGCCGGCGCGGCCCTGGCACGGGGATCTGCC GGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTGACTGACTGACTGACTGACAGGTATTCCGTTTCTCGCAGTCCACT TTTAAAAACATAACGTC
Citation	Frowein J, Campbell K, Götz M. Expression of Ngn1, Ngn2, Cash1, Gsh2 and Sfrp1 in the developing chick telencephalon. Mech Dev. 2002 Jan;110(1-2):249-52.
Copyright	Copyright © 2002 Elsevier Science Ireland Ltd. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI XM_421783.2

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

31-32

stage 32

Telencephalon

Entry 7

GEISHA Id	EMX2.Manning.2007	Data Source	Publication
Complete cDNA Template Probe	show GGGCGGTGGAACGCGGACCGACCCGGAGCGAAGCGAGAGGGGGGCAACCGCGCAGGGACCGCGGGGCACCGCGTTACAC CCAGTCACTCCCCGCTGCAAACTTCCCCGGATCGCCTCCTCCCGCGCACCGCAGAGCCACGCACAGATTTGCCGGGGGA CGCCCGCCGCCGCCGCACCATGTTTCAGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTCGCTGGTGGCCAAAGACAGC CCCTTGCCCGCGTCTCGCTCCGAGGATCCCATCCGCCCGGCGGCTCTCAGCTATGCCAATTCCAGCCCGATGAACCCTT TTCTCAACGGCTTCCACTCCACCGGCAGGGGGGTCTACTCCAACCCGGACTTGGTCTTTGCGGAGGCCGTCTCCCACCC GCCGAACCCGGCCGTGCCCGTGCACCCCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCCGCTGCCCGCCTCGCACTCC ACGCACCCGCTCTTCGCTTCGCAGCAAAGGGATCCCTCCACCTTCTACCCGTGGCTAATACACCGCTACCGGTATCTGG GCCACAGGTTCCAAGGGAACGAGACCAGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGGCCAGGAAACCCAAACGGAT CCGTACAGCTTTCTCCCCGTCCCAATTACTGAGACTGGAACATGCCTTTGAGAAGAACCATTATGTGGTGGGAGCGGAG AGAAAGCAGCTGGCACACAGCCTCAGCCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACAGAAGGACAAAGTTCA AGCGGCAAAAGTTGGAAGAGGAAGGTTCGGACTCACAACAGAAGAAAAAAGGGACTCATCACATTAACCGGTGGAGAAT CGCCACCAAACAAGCCAGTCCAGAAGAAATCGACGTCACGTCGGACGATTAAAAAACTGGCACTTTGGGACTTTTCAAG CCAGCCAACGCATCGAGAGAAAGTGTTAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGGAAGGGACACGGAGAGCTT CATCCAAACGCGATTCCCGTCTGGAGGGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTGCGGAGCGCGGCGCTGCCG GCGCGGCCCTGGCACGGGGATCTGCCGGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTGACTGACTGACTGACTGAC AGGTATTCCGTTTCTCGCAGTCCACTTTTAAAAACATAACGTCAAAAAAAAAAAAAAAAAAAAAA
Citation	Manning L, Ohyama K, Saeger B, Hatano O, Wilson SA, Logan M, Placzek M. Regional morphogenesis in the hypothalamus: a BMP-Tbx2 pathway coordinates fate and proliferation through Shh downregulation. Dev Cell. 2006 Dec;11(6):873-85.
Copyright	Copyright © 2006 Elsevier Inc. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI XM_421783.3

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 15

stage 18

Hypothalamus

double labeled

Entry 8

GEISHA Id	EMX2.Malashichev.2005	Data Source	Publication
Complete cDNA Template Probe	show GGGCGGTGGAACGCGGACCGACCCGGAGCGAAGCGAGAGGGGGGCAACCGCGCAGGGACCGCGGGGCACCGCGTTACAC CCAGTCACTCCCCGCTGCAAACTTCCCCGGATCGCCTCCTCCCGCGCACCGCAGAGCCACGCACAGATTTGCCGGGGGA CGCCCGCCGCCGCCGCACCATGTTTCAGCCCGCGCCCAAGCGCTGTTTCACCATCGAGTCGCTGGTGGCCAAAGACAGC CCCTTGCCCGCGTCTCGCTCCGAGGATCCCATCCGCCCGGCGGCTCTCAGCTATGCCAATTCCAGCCCGATGAACCCTT TTCTCAACGGCTTCCACTCCACCGGCAGGGGGGTCTACTCCAACCCGGACTTGGTCTTTGCGGAGGCCGTCTCCCACCC GCCGAACCCGGCCGTGCCCGTGCACCCCGTGCCCCCTCCCCACGCCCTGGCCGCCCATCCGCTGCCCGCCTCGCACTCC ACGCACCCGCTCTTCGCTTCGCAGCAAAGGGATCCCTCCACCTTCTACCCGTGGCTAATACACCGCTACCGGTATCTGG GCCACAGGTTCCAAGGGAACGAGACCAGCCCGGAGAGCTTCCTCCTGCACAACGCTCTGGCCAGGAAACCCAAACGGAT CCGTACAGCTTTCTCCCCGTCCCAATTACTGAGACTGGAACATGCCTTTGAGAAGAACCATTATGTGGTGGGAGCGGAG AGAAAGCAGCTGGCACACAGCCTCAGCCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACAGAAGGACAAAGTTCA AGCGGCAAAAGTTGGAAGAGGAAGGTTCGGACTCACAACAGAAGAAAAAAGGGACTCATCACATTAACCGGTGGAGAAT CGCCACCAAACAAGCCAGTCCAGAAGAAATCGACGTCACGTCGGACGATTAAAAAACTGGCACTTTGGGACTTTTCAAG CCAGCCAACGCATCGAGAGAAAGTGTTAAAGGCTCCCTCACCCCGGCGTGGCGGTGCGGGGAAGGGACACGGAGAGCTT CATCCAAACGCGATTCCCGTCTGGAGGGCGGCGGCGAACGGCGGGGGCAGAGCGCGAGGTGCGGAGCGCGGCGCTGCCG GCGCGGCCCTGGCACGGGGATCTGCCGGGCAGAGCCCAGCGCCGGGACGAGGGAATGACTGACTGACTGACTGACTGAC AGGTATTCCGTTTCTCGCAGTCCACTTTTAAAAACATAACGTCAAAAAAAAAAAAAAAAAAAAAA
Citation	Malashichev Y, Borkhvardt V, Christ B, Scaal M. Differential regulation of avian pelvic girdle development by the limb field ectoderm. Anat Embryol (Berl). 2005 Oct;210(3):187-97. Epub 2005 Oct 18.
Copyright	© Springer, Part of Springer Science+Business Media
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (Acc. # XM_421783.3).