GEISHA - A Chicken Embryo Gene Expression Database
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_

ENG
endoglin

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolENG
Official Full Nameendoglin
CGNC ID56870
also known asendoglin|endoglin (Osler-Rendu-Weber syndrome 1)
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001080887
PolypeptideNP_001074356
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.31780
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human2022ENSG00000106991MIM:187300MIM:131195
Mouse13805ENSMUSG00000026814All phenotypic alleles (7):Targeted, knock-out(2) Targeted, other(4) Gene trapped(1) MGI:95392
Xenopus
Zebrafish
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene771557
Ensembl GeneENSGALG00000005060
KEGGgga:771557

Entry 1

GEISHA IdENG.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerCCCAGACAGCAGCAAAACAATC
Reverse cDNA Template PrimerAATTAACCCTCACTAAAGCCTTCACTTCCAAAACCTTCTCGcDNA Template Length991
Forward cDNA Template Probeshow
CTGGCCTCCGGAACCTACAAGATCCTGCACTTCCCCATGGACCCACGTAAAGGGGAGCTGCTGCCCGACACGGAGCAGG
GCCTCATTGCCAAAGCCTTTGAGAAGAACTACAGCATCATCGCCTCCTACTCCGTCATCCCCATCAGCCCCCACATCAC
ACTGAATATCCACGAGCGTGAGGTGCCGAAGAAGCTGCCTGTGGGGCCCACCTCGTCAGCCCCTAGCCCTGACGACGTG
TCTAGCAGTCTGCTCTTCACGCTCAGTCCCTGGAAGTGCACGGATGACACCATGGAAATCGTCATCGCCAGGTCCAACC
TGGAGCCCATCAAGGACGTGGTGAACATCACCCTGCGGGACATCAGCTGCCAGGCTGAGAAGAACGCCACACACTTCAT
GCTGCACACCCTGCTCAGCCACTGCGGCACCTCGCTGGAGAACCACGGCCATGCCAACAACGAGTTCGTCCTCAGCCTG
TCCAAGGGCTCGGTGCTCAGGAGCGTGCGGGTGGCCTTCCAGTGCCCGATCCCACGGGAGCTCTTCCTGCGCCTCTTCC
CCTCCGCCGCCTTCAAGGCACCGCAGACAGAGCTGGAGGTCAACAAGGAGGTGTTTGTGCAGGCATCCATGCACTTGGA
GGACTACCCGGCCGACCTGCAGCTCAAGGAGTGCTACCTGATGGCCCCCGGCATGGAGCCGCTGCTGCTGGTGCAGGGC
AACAAGGCGCAGAGCTCCAGCGTGGCCATGCTGGAGGAGCCCCCCAGCAACCGGGCCAGGAAGGTCTGGCGCTTCCGCT
TCACCTACACCGTCCCCGAGGGCAGGCACGTCCCCTTCTCCGCCACCCTCAAGTGCAAGGCTGGGCTGCAGAACAACAC
CATCTTCGAGAAGGTTTTGGA
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 5
stage 6
Area Opaca
Area Pellucida
Blood Islands
Hensen's Node
Primitive Streak
 
7-12
stage 7
stage 8
stage 8
stage 9
stage 9
stage 10
stage 10
stage 10
stage 11
stage 12
stage 12
Area Opaca
Area Pellucida
Blood Islands
Blood Vessels
Endocardium
Extraembryonic Blood Vessels
Hensen's Node
Primitive Streak
Ventral view.
13-18
stage 13
stage 14
stage 15
stage 17
stage 18
Blood Islands
Blood Vessels
Endocardium
Extraembryonic Blood Vessels
Ventral view.
19-24
stage 19
stage 21
stage 22
stage 22
stage 22
stage 23
Allantois
Blood Vessels
Endocardium
Extraembryonic Blood Vessels
 
25
stage 25
Allantois
Blood Vessels
Endocardium
Extraembryonic Blood Vessels
 

Entry 2

GEISHA IdEndoglin.Mercado-Pimentel.2007Data SourcePublication
Complete cDNA Template Probeshow
ATGTGCCGTCGGAGCTCTCCGCTGCTGCCGCTGCTGCTGGCGCTGCTCGGCCGTCCCGACCCCGCTCCAGCCGAGCACT
GCGACTTGCAGCCGGTGACAGCAGAGCCGCCCATCACGCTGTTCTACACCACCAGCACGGTGCTGCGGGGCTGCGTCAG
CAACAGCTCTACATTAGCCAGCCATGAAGTGCACGTCCTCAGCATCCAGTGGTCCAAGACCCCTGTCCCCATGCTGAAT
GTGTCCATCACGCCACGGGATGATGACTGCACCCGGCCAGCAGCACTCATCCTCCAGTGCACACAGTGCTTGGCCAGCA
TCACCCTCCCGTGCCAGAACCTCCTCATCCACACTGACGCCTCTCTGAGACCCAAGGTGCAGGGCAAGGAGCTGCCAAA
GGATGCCAAGGGACATCTGCTGGAGTGGGTGCAGAGGACCTATGGGGGCATCACATCCTACAGCGAGCTGAAGGACCCA
CAGAGGATCCACCTCCAGCTGGGCGAAAATAGCAACAGCCCCCAGAACTGCATTCCCCAGAAGGACTTCGATGCCACGC
CGCATCTCGAGGCTGAGGTCCTCTTCCGTGAGGTGAAGGGCTGTACCAGCAGCAGTGCCCAGAGTGCCGGGGCTGCCCA
CATTGTCCAGCTGCTGCACAAGCCCAGCTTGCCCATCACGGAGGTGAAGCTGACCCTGAACTGCCCCAGACAGCAGCAA
AACAATCAGATCCTCCTCCTGCAGGGCCCGGCCAACCTCACCTGGCTCCTGATGCTGAACAACTGCAGCCTTCAGTTCC
TGGCCTCCGGAACCTACAAGATCCTGCACTTCCCCATGGACCCACGTAAAGGGGAGCTGCTGCCCGACACGGAGCAGGG
CCTCATTGCCAAAGCCTTTGAGAAGAACTACAGCATCATCGCCTCCTACTCCGTCATCCCCATCAGCCCCCACATCACA
CTGAATATCCACGAGCGTGAGGTGCCGAAGAAGCTGCCTGTGGGGCCCACCTCGTCAGCCCCTAGCCCTGACGACGTGT
CTAGCAGTCTGCTCTTCACGCTCAGTCCCTGGAAGTGCACGGATGACACCATGGAAATCGTCATCGCCAGGTCCAACCT
GGAGCCCATCAAGGACGTGGTGAACATCACCCTGCGGGACATCAGCTGCCAGGCTGAGAAGAACGCCACACACTTCATG
CTGCACACCCTGCTCAGCCACTGCGGCACCTCGCTGGAGAACCACGGCCATGCCAACAACGAGTTCGTCCTCAGCCTGT
CCAAGGGCTCGGTGCTCAGGAGCGTGCGGGTGGCCTTCCAGTGCCCGATCCCACGGGAGCTCTTCCTGCGCCTCTTCCC
CTCCGCCGCCTTCAAGGCACCGCAGACAGAGCTGGAGGTCAACAAGGAGGTGTTTGTGCAGGCATCCATGCACTTGGAG
GACTACCCGGCCGACCTGCAGCTCAAGGAGTGCTACCTGATGGCCCCCGGCATGGAGCCGCTGCTGCTGGTGCAGGGCA
ACAAGGCGCAGAGCTCCAGCGTGGCCATGCTGGAGGAGCCCCCCAGCAACCGGGCCAGGAAGGTCTGGCGCTTCCGCTT
CACCTACACCGTCCCCGAGGGCAGGCACGTCCCCTTCTCCGCCACCCTCAAGTGCAAGGCTGGGCTGCAGAACAACACC
ATCTTCGAGAAGGTTTTGGAAGTGAAGGTGAAGGACGTCTGGCGGCTGCCCAACAACCAAGGGCTGGGGCTGTCCGCCG
TGCTGGGCATCACCTTTGGAGCCTTCCTCATCGGCGCACTCCTCACTGCTGGGCTCTGGTATATCTACTCGCATACCCG
TCCCATCTCCAAACTGCAGCCGGTTTCCACCACAGCACCAGCCTCGGAGAGCAGCAGCACCAACCACAGCATTGGCAGC
ACCCAGAGCACCCCCTGCTCCACCAGCAGCATGGCCTGA
CitationMercado-Pimentel ME, Hubbard AD, Runyan RB. Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation. Dev Biol. 2007 Apr 1;304(1):420-32.
CopyrightReprinted with permission from Elsevier. Copyright © 2007 Elsevier B.V. All rights reserved.
CommentsAuthors said:probe was made from a fragment of 488 bp of the chicken endoglin complete sequence AY702002 corresponding to base pairs 1033 to 152 (extracellular domain). The entire AY702002 is shown here.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 15
stage 16
stage 17
stage 17
stage 17
stage 18
Blood Vessels
Cardinal Veins
Endocardium
Outflow Tract
Proepicardium
 

Entry 3

GEISHA IdENDOGLIN.Alev.2010Data SourcePublication
Complete cDNA Template Probeshow
AGAACCTCCTCATCCACACTGACGCCTCTCTGAGACCCAAGGTGCAGGGCAAGGAGCTGCCAAAGGATGCCAAGGGACA
TCTGCTGGAGTGGGTGCAGAGGACCTATGGGGGCATCACATCCTACAGCGAGCTGAAGGACCCACAGAGGATCCACCTC
CAGCTGGGCGAAAATAGCAACAGCCCCCAGAACTGCATTCCCCAGAAGGACTTCGATGCCACGCCGCATCTCGAGGCTG
AGGTCCTCTTCCGTGAGGTGAAGGGCTGTACCAGCAGCAGTGCCCAGAGTGCCGGGGCTGCCCACATTGTCCAGCTGCT
GCACAAGCCCAGCTTGCCCATCACGGAGGTGAAGCTGACCCTGAACTGCCCCAGACAGCAGCAAAACAATCAGATCCTC
CTCCTGCAGGGCCCGGCCAACCTCACCTGGCTCCTGATGCTGAACAACTGCAGCCTTCAGTTCCTGGCCTCCGGAACCT
ACAAGATCCTGCACTTCCCCATGGACCCACGTAAAGGGGAGCTGCTGCCCGACACGGAGCAGGGCCTCATTGCCAAAGC
CTTTGAGAAGAACTACAGCATCATCGC
CitationAlev C, McIntyre BA, Ota K, Sheng G. Dynamic expression of Endoglin, a TGF-beta co-receptor, during pre-circulation vascular development in chick. Int J Dev Biol. 2010;54(4):737-42.
Copyright© UBC Press
CommentsThe cDNA template used to generate the probe was obtained by PCR as described in the paper.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 4
stage 4
stage 4
stage 6
Extraembryonic Mesoderm
Head Process
Hensen's Node
Stage 4+
7-12
stage 7
stage 7
stage 7
stage 7
stage 8
stage 8
stage 8
stage 8
stage 8
stage 10
stage 10
stage 10
stage 10
stage 10
stage 10
stage 10
stage 12
stage 12
stage 12
stage 12
stage 12
stage 12
stage 12
stage 12
Area Opaca
Blood
Blood Islands
Cardiovascular
Endocardium
Endothelial Cells
Extraembryonic Blood Vessels
Heart
Lateral Plate Mesoderm
Nephric Ducts
Paraxial Mesoderm
Splanchnic Mesoderm
Unlabeled
endocardial cell
endocardial precursors
lateral plate vessels
somatopleural vessels
13
stage 13
stage 13
stage 13
stage 13
Aorta
Blood Vessels
Endocardium
Extraembryonic Blood Vessels
Face Mesenchyme
Heart
Tail
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.31780

Mouse

EmageMGI:95392
EurexpressMGI:95392
MGI GXDMGI:95392

Frog

Xenbase

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFIN
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