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EFNA2 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol EFNA2 Official Full Name ephrin A2 CGNC ID 49502 also known as ELF-1, ephrin-A2|EPH-related receptor tyrosine kinase ligand 6|Eph ligand family-1|LERK-6 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Entrez Gene Ensembl Gene Genetic Phenotypes MOD Fruit Fly Human Mouse Xenopus Zebrafish
Gene Ontology Links to other databases
Entry 1 GEISHA Id EFNA2.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer TTATAAAAGCTTGCGGCCGCAGAATATACCGCTACGCCGTCTATTGG Reverse cDNA Template Primer GCTCTAGAAATTAACCCTCACTAAAGGAGTTGTTGCTGGTGAAGATGGG cDNA Template Length 444 Forward cDNA Template Probe show AACGCAGCAACCCCAGGGTTCACCGGNGGGGGATTACACCGNTGGAGGTGAGCATCAATGACTACCTGGGACATCTACT
Entry 2 GEISHA Id EphrinA2.Baker.2003 Data Source Publication Complete cDNA Template Probe show CCGCGCTGGGAGGCGGCCGCGCTGCTCGCCGCGATCGTCGGCGTCTGCGTGTGGAGCGACGACCCCGGCAAAGTGATCT
Citation Baker RK, Antin PB. Ephs and ephrins during early stages of chick embryogenesis Dev Dyn. 2003 Sep;228(1):128-42. Copyright 2003 Wiley-Liss, Inc. Comments EphrinA2 transcripts are present throughout the mesoderm (as determined from sectioned embryos, not shown) during stages 4-7; during this period, low levels of transcripts are also present in the primitive streak (Fig. 1A-C). Between stages 7 and 12, ephrinA2 is strongly expressed throughout the neurogenic ectoderm, particularly in the posterior half of the mesencephalon (the prospective midbrain). After stage 7, ephrinA2 expression continues in the head mesenchyme and cardiogenic mesoderm but is down-regulated in the mesoderm posterior to the heart-forming region.
Entry 3 GEISHA Id ELF-1.Dube.2007 Data Source Publication Complete cDNA Template Probe show CCGCCGCCCGCTGAGCCGCTCCGCTCCGCCGGGACGATGCCGCGCTGGGAGGCGGCCGCGCTGCTCGCCGCGATCGTCG
Citation Dube A, Thai S, Gaspar J, Rudders S, Libermann TA, Iruela-Arispe L, Oettgen P.
Elf-1 is a transcriptional regulator of the Tie2 gene during vascular development.
Circ Res. 2001 Feb 2;88(2):237-44. Copyright Copyright © 2007 UBC Press Comments Authors said The cELF-1 cDNA fragment used to generate the probe is 700 bp in length and encodes the first 100 amino acids of the cELF-1 protein and 100 bp of the 5' untranslated region. The sequence listed above is NCBI Acc# NM_204983.
Entry 4 GEISHA Id EPHRINA2.Takahashi.2003 Data Source Publication Complete cDNA Template Probe show AGCGACGACCCCGGCAAAGTGATCTCGGACCGCTACGCCGTCTATTGGAACCGCAGCAACCCCAGGTTCCACCGCGGGG
Citation Takahashi H, Shintani T, Sakuta H, Noda M. CBF1 controls the retinotectal topographical map along the anteroposterior axis through multiple mechanisms. Development. 2003 Nov;130(21):5203-15. Epub 2003 Sep 3. Copyright Published by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Comments Authors indicated the probe was the 541 bp fragment of chick ephrin A2 (94-634; L40932).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 18
stage 18
stage 18
stage 18
Retina 19-24 stage 23
Retina 31-34 stage 34
stage 34
stage 34
stage 34
stage 34
stage 34
stage 34
Retina
Entry 5 Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-15 stage 13
stage 13
stage 13
stage 15
stage 15
Eye Head Mesenchyme Midbrain all
Entry 6 GEISHA Id ephrin‐A2.Iwamasa.1999 Data Source Publication Complete cDNA Template Probe show CCGCCGCCCGCTGAGCCGCTCCGCTCCGCCGGGACGATGCCGCGCTGGGAGGCGGCCGCGCTGCTCGCCGCGATCGTCG
Citation Iwamasa H, Ohta K, Yamada T, Ushijima K, Terasaki H, Tanaka H. Expression of Eph receptor tyrosine kinases and their ligands in chick embryonic motor neurons and hindlimb muscles. Dev Growth Differ. 1999 Dec;41(6):685-98. Copyright Copyright © 1999 John Wiley & Sons, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204983.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-27 stage 27
stage 27
stage 27
stage 27
Spinal Cord
Data from NCBI Unigene EST ProfileGga.2416
Mouse Frog Fruit Fly Zebra Finch Zebrafish
