GEISHA - A Chicken Embryo Gene Expression Database
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APOA1
apolipoprotein A1

Gene
Official SymbolAPOA1
Official Full Nameapolipoprotein A1
CGNC ID49860
also known asapolipoprotein A-I|apo-AI|apoA-I, Apo-AI, Apolipoprotein A-I precursor
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205525
PolypeptideNP_990856
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.34313
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human
Mouse
Xenopus
Zebrafish
Gene Ontology
Molecular Functionapolipoprotein A-I receptor binding, beta-amyloid binding, cholesterol binding, more...cholesterol transporter activity, enzyme binding, high-density lipoprotein particle binding, high-density lipoprotein particle receptor binding, identical protein binding, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding
Biological Processadrenal gland development, blood vessel endothelial cell migration, cholesterol biosynthetic process, more...cholesterol efflux, cholesterol homeostasis, cholesterol import, endothelial cell proliferation, glucocorticoid metabolic process, G-protein coupled receptor signaling pathway, high-density lipoprotein particle assembly, lipid storage, lipoprotein biosynthetic process, myoblast differentiation, negative regulation of cell adhesion molecule production, negative regulation of cytokine secretion involved in immune response, negative regulation of heterotypic cell-cell adhesion, negative regulation of hydrolase activity, negative regulation of inflammatory response, negative regulation of interleukin-1 beta secretion, negative regulation of tumor necrosis factor-mediated signaling pathway, negative regulation of very-low-density lipoprotein particle remodeling, peptidyl-methionine modification, phosphatidylcholine biosynthetic process, phospholipid efflux, phospholipid homeostasis, positive regulation of cholesterol esterification, positive regulation of hydrolase activity, positive regulation of transferase activity, protein oxidation, protein stabilization, regulation of Cdc42 protein signal transduction, regulation of intestinal cholesterol absorption, regulation of protein phosphorylation, reverse cholesterol transport, triglyceride homeostasis
Cellular Componentendocytic vesicle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle
Links to other databases
Entrez Gene396536
Ensembl GeneENSGALG00000007114
KEGGgga:396536

Entry 1

GEISHA IdR49Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GGAGCAGTGCGGAGCAGCGGCAGGAGAGCGCCGGTTCAGCGCGAAGATGAGAGGCGTGCTGGTGACCCTCGCTGTGCTC
TTCCTGACGGGCACCCAGGCCCGCTCCTTCTGGCAGCACGATGAGCCCCAGACGCCCCTGGACCGCATTCGGGATATGG
TGGACGTCTACCTGGAGACGGTGAAGGCCAGCGGCAAGGATGCCATCGCCCAGTTCGAGTCCTCTGCTGTGGGCAAACA
GCTTGACCTGAAGCTGGCTGACAACCTGGACACGCTGAGTGCCGCGGCTGCCAAGCTGCGTGAGGACATGGCTCCCTAC
TACAAGGAGGTGCGCGAGATGTGGCTGAAGGACACCGAGGCTCTGCGTGCTGAGCTCACCAAGGACCTGGAGGAGGTGA
AGGAGAAGATCCGGCCCTTCCTGGACCAGTTCTCCGCCAAGTGGACGGAGGAGCTGGAGCAGTACCGNC
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
Area Opaca
Extraembryonic
 
7-12
stage 7
Area Opaca
Extraembryonic
 
13
stage 13
Anterior Intestinal Portal
Extraembryonic
 

Entry 2

GEISHA IdG39Data SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
GGCGGCAGGAGAGCGCCGGTTCAGCGCGAAGATGAGAGGCGTGCTGGTGACCCTCGCTGTGCTCTTCCTGACGGGCACC
CAGGCCCGCTCCTTCTGGCAGCACGATGAGCCCCAGACGCCCCTGGACCGCATTCGGGATATGGTGGACGTCTACCTGG
AGACGGTGAAGGCCAGCGGCAAGGATGCCATCGCCCAGTTCGAGTCCTCTGCTGTGGGCAAACAGCTTGACCTGAAGCT
GGCTGACAACCTGGACACGCTGAGTGCCGCGGCTGCCAAGCTGCGTGAGGACATGGCTCCCTACTACAAGGAGGTGCGC
GAGATGTGGCTGAAGGACACCGAGGCTCTGCGTGCTGAGCTCACCAAGGACCTGGAGGAGGTGAAGGAGAAGATCCGGC
CCTTCCTGGACCAGTTCTCCGCCAAGTGGACGGAGGAGCTGGAGCAGTACCGCCAGCGCCTGACGCCCGTGGCTCAGGA
GCTGAAGGAGCTCACCAAGCAGAAGGTGGAGCTGATGCAGGCCAAGCTGACCCCGGTGGCTGAGGAGGCGCGGGATCGT
CTGCGTGGGCACGTGGAGGAGCTGCGCAAGAACCTGGCGCCATACAGCGATGAGCTGCGGCAGAAGCTGAGCCAGAAGC
TGGAGGAGATCCGTGAGAAGGGCATCCCCCAGGCTTCCGAGTACCAGGCCAAGGTGATGGAGCAGCTCAGCAACCTGCG
TGAGAAGATGACGCCTCTGGTGCAGGAATTCAGGGAGCGCCTCACCCCCTATGCTGAGAACCTCAAGAACCGCTTGATC
TCCTTCCTGGACGAACTCCAGAAGTCCGTGGCCTGAGCTGCCGGCCCAGGGACTGACCCCAGGCCATGCTGGCCTCCGG
GAGTCCTCGGGGACCCCTCCTTAATCTCCTCTCCCCCCCCGACCCGGAGTCCGTCTCAACTTTGCCATTCTTTTGTCAA
ATAAACATGACCTGAAGT
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 5
stage 6
Area Opaca
Extraembryonic
ventral
7-12
stage 8
stage 10
stage 11
stage 11
Area Opaca
Endoderm, early
Extraembryonic
 
19-22
stage 20
stage 20
stage 22
Amnion
Yolk Sack or Stalk
 

Entry 3

GEISHA IdO39Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GGAGCAGTGCGGAGCAGCGGCAGGAGAGCGCCGGTTCAGCGCGAAGATGAGAGGCGTGCTGGTGACCCTCGCTGTGCTC
TTCCTGACGGGCACCCAGGCCCGCTCCTTCTGGCAGCACGATGAGCCCCAGACGCCCCTGGACCGCATTCGGGATATGG
TGGACGTCTACCTGGAGACGGTGAAGGCCAGCGGCAAGGATGCCATCGCCCAGTTCGAGTCCTCTGCTGTGGGCAAACA
GCTTGACCTGAAGCTGGCTGACAACCTGGACACGCTGAGTGCCGCGGCTGCCAAGCTGCGTGAGGACATGGCTCCCTAC
TACAAGGAGGTGCGCGAGATGTGGCTGAAGGACACCGAGGCTCTGCGTGCTGAGCTCACCAAGGACCTGGAGGAGGTGA
AGGAGAAGATCCGGCCCTTCCTGGACCAGTTCTCCGCCAAGTGGACGGAGGAGCTGGAGCAGTACCGCCAGCGCCTGAC
GCCCGTGGCTCAGGAGCTGAAGGAGCTCACCAAGCAGAAGGTGGAGCTGATGCAGGCCAAGCTGACCCCGGTGGCTGAG
GAGGCGCGGGATCGTCTGCG
Commentsolder stages not yet available
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 5
Area Opaca
Extraembryonic
 
7-9
stage 9
Area Opaca
Extraembryonic
 

Entry 4

GEISHA IdAPOA1.Bertocchini.2008Data SourcePublication
Complete cDNA Template Probeshow
TCGGGACGAGCAGTGCGGAGAGCGGCAGGAGAGCGCCGGTTCAGCACGAAGATGAGAGGCGTGCTGGTGACCCTCGCTG
TGCTCTTCCTGACGGGCACCCAGGCCCGCTCCTTCTGGCAGCACGATGAGCCCCAGACGCCCCTGGACCGCATTCGGGA
TATGGTGGACGTCTACCTGGAGACGGTGAAGGCCAGCGGCAAGGATGCCATCGCCCAGTTCGAGTCCTCTGCTGTGGGC
AAACAGCTTGACCTGAAGCTGGCTGACAACCTGGACACGCTGAGTGCCGCGGCTGCCAAGCTGCGTGAGGACATGGCTC
CCTACTACAAGGAGGTGCGCGAGATGTGGCTGAAGGACACCGAGGCTCTGCGTGCTGAGCTCACCAAGGACCTGGAGGA
GGTGAAGGAGAAGATCCGGCCCTTCCTGGACCAGTTCTCCGCCAAGTGGACGGAGGAGCTGGAGCAGTACCGCCAGCGC
CTGACGCCCGTGGCTCAGGAGCTGAAGGAGCTCACCAAGCAGAAGGTGGAGCTGATGCAGGCCAAGCTGACCCCGGTGG
CTGAGGAGGCGCGGGATCGTCTGCGTGGGCACGTGGAGGAGCTGCGCAAGAACCTGGCGCCATACAGCGATGAGCTGCG
GCAGAAGCTGAGCCAGAAGCTGGAGGAGATCCGTGAGAAGGGCATCCCCCAGGCTTCCGAGTACCAGGCCAAGGTGATG
GAGCAGCTCAGCAACCTGCGTGAGAAGATGACGCCTCTGGTGCAGGAATTCAGGGAGCGCCTCACCCCCTATGCTGAGA
ACCTCAAGAACCGCTTGATCTCCTTCCTGGACGAACTCCAGAAGTCCGTGGCCTGAGCTGCCGGCCCAGGGACTGACCC
CAGCCATGCTGGCCTCCGGGAGTCCTCGGGGACCCCTCCTTAATCTCCTCTCCCCCCCCGACCCGGAGTCCGTCTCAGC
TTTGCCATTCTTTTGTCAAATAAACATGACTTAAGTTATTGGAGCTC
CitationFederica Bertocchini, Claudio D Stern (2008). A differential screen for genes expressed in the extraembryonic endodermal layer of pre-primitive streak stage chick embryos reveals expression of Apolipoprotein A1 in hypoblast, endoblast and endoderm. Gene Expression Patterns, Volume 8, Issues 7-8, September 2008, Pages 477-480, ISSN 1567-133X, DOI: 10.1016/j.gep.2008.07.001.
CopyrightCopyright © 2008 Elsevier B.V. All rights reserved.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205525).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
X-XIV
stage XI
stage XI
stage XI
stage XI
stage XI
stage XI
Hypoblast
Endoblast
Endoblast, double labeled
Late XIII EG&K
Stage XI EG&K
Stage XII EG&K
Stage XII/XIII EG&K
Stage XIII EG&K
Stage XIV EG&K
1-3
stage 2
stage 3
stage 3
stage 3
Germinal Crescent
Hypoblast
Endoblast
Endoblast, double label
4-6
stage 4
stage 4
stage 5
stage 5
stage 6
Early Endoderm
Extraembryonic
extra-embryonic lower layer
extra-embryonic lower layer, double labeled
extraembryonic lower layer, double labeled
7-12
stage 8
stage 9
stage 12
Anterior Intestinal Portal
Early Endoderm
extra-embryonic lower layer
extra-embryonic lower layer
13-16
stage 13
stage 14
stage 16
Anterior Intestinal Portal
Endoderm
Liver
 

Entry 5

GEISHA IdAPOA1.Anderson.2020Data SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
TCGGGACGAGCAGTGCGGAGAGCGGCAGGAGAGCGCCGGTTCAGCACGAAGATGAGAGGCGTGCTGGTGACCCTCGCTG
TGCTCTTCCTGACGGGCACCCAGGCCCGCTCCTTCTGGCAGCACGATGAGCCCCAGACGCCCCTGGACCGCATTCGGGA
TATGGTGGACGTCTACCTGGAGACGGTGAAGGCCAGCGGCAAGGATGCCATCGCCCAGTTCGAGTCCTCTGCTGTGGGC
AAACAGCTTGACCTGAAGCTGGCTGACAACCTGGACACGCTGAGTGCCGCGGCTGCCAAGCTGCGTGAGGACATGGCTC
CCTACTACAAGGAGGTGCGCGAGATGTGGCTGAAGGACACCGAGGCTCTGCGTGCTGAGCTCACCAAGGACCTGGAGGA
GGTGAAGGAGAAGATCCGGCCCTTCCTGGACCAGTTCTCCGCCAAGTGGACGGAGGAGCTGGAGCAGTACCGCCAGCGC
CTGACGCCCGTGGCTCAGGAGCTGAAGGAGCTCACCAAGCAGAAGGTGGAGCTGATGCAGGCCAAGCTGACCCCGGTGG
CTGAGGAGGCGCGGGATCGTCTGCGTGGGCACGTGGAGGAGCTGCGCAAGAACCTGGCGCCATACAGCGATGAGCTGCG
GCAGAAGCTGAGCCAGAAGCTGGAGGAGATCCGTGAGAAGGGCATCCCCCAGGCTTCCGAGTACCAGGCCAAGGTGATG
GAGCAGCTCAGCAACCTGCGTGAGAAGATGACGCCTCTGGTGCAGGAATTCAGGGAGCGCCTCACCCCCTATGCTGAGA
ACCTCAAGAACCGCTTGATCTCCTTCCTGGACGAACTCCAGAAGTCCGTGGCCTGAGCTGCCGGCCCAGGGACTGACCC
CAGCCATGCTGGCCTCCGGGAGTCCTCGGGGACCCCTCCTTAATCTCCTCTCCCCCCCCGACCCGGAGTCCGTCTCAGC
TTTGCCATTCTTTTGTCAAATAAACATGACTTAAGTTATTGGAGCTC
CommentsImages Provided by Claire Anderson; Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_205525.4).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-15
stage 13
stage 15
Anterior Intestinal Portal
Endoderm
Liver
Somites
Yolk Sack or Stalk
extraembryonic endoderm
extraembryonic mesoderm
ventral
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.34313

Mouse

Emage
Eurexpress
MGI GXD

Frog

Xenbase

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFIN
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