GEISHA - A Chicken Embryo Gene Expression Database
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HDAC4
histone deacetylase 4

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolHDAC4
Official Full Namehistone deacetylase 4
CGNC ID49084
also known ashistone deacetylase 4|HD4|osteoblast regulatory factor 3A
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204313
PolypeptideNP_989644
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.3689
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly32278FBgn0041210
Human9759ENSG00000068024MIM:600430MIM:605314
Mouse208727ENSMUSG00000026313All phenotypic alleles (4):Targeted, knock-out(2) Targeted, other(1) Gene trapped(1) MGI:3036234
Xenopus100489340488766
Zebrafish568877ENSDARG00000041204ZDB-GENE-061013-95ZFIN:ZDB-GENE-061013-95
Gene Ontology
Molecular Functionhistone deacetylase activity, metal ion binding, more...NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), transcription factor binding
Biological ProcessB cell activation, B cell differentiation, chromatin modification, chromatin organization, more...histone deacetylation, inflammatory response, negative regulation of striated muscle tissue development, negative regulation of transcription, DNA-templated, nervous system development, transcription, DNA-templated
Cellular Componenthistone deacetylase complex
Links to other databases
Entrez Gene374207
Ensembl GeneENSGALG00000004288
KEGGgga:374207
GEISHA IdHDAC4.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerGAATGGATTTGCTGTTGTTCGG
Reverse cDNA Template PrimerATTAACCCTCACTAAAGGTGGGTTCATCATCAGGTCGCcDNA Template Length860
Forward cDNA Template Probeshow
AGCTGGCTTCCGCCTACCGACAGAANATGCCATGGGCTGGTCACTGTCTCAGCCTCTTCATTCTCACACTTCTGTGCCT
CAACCAGGGAGTAGCCCACTGTGGAGGCGTAGCGCTGGAGTGAATGCCAATACTTGCTGTGTATCTCAATCACTTTCTC
CATTGAATGCACCGCATTAGCATTTGCTCTCTGCTGGAGAACCTTTTCTGGAAGAGGGTCAAGCTCGTTTCCCAGCAAA
GCAGAAACACATGCTTCTGAGGCATCGCAAATGGCAGTCAGGTCGTGGCCTCCTTCGAGGGCCAGGACGACGCGGCCTC
CAGCCAGGCCCATCAGCTGCTTCGTCAGGTACCCAAAGCATTTTGCAGAGAGATTGTATCCTCCCAGAGGCGTAGGATG
GCCTTCCACTGCATCAAAACCAGATGACACGAGCACAACATCTGGGGCAAACTCATTGGCAATGGGCATTACGACCGTT
CTGAAAGCAGTCAAGTACTCTGTGTCTCCCATCGGCGGATCAAGGCCACCAGTAAATGCCATGTTAACATTGAACCCAA
CTCCTGCTCCTGTGCCAACCTCATCAGGAGCACCACTGCCTGGAAAGAAGTTCCCATCATCATAGCGATGTAGTGAAAT
ATAAAGAACATTAGGATCATTGTAGAAAGCTTGCTGAGTACCGTTCCCATGGTGTACATCCCAGTCCACTATGAGGATT
TTGCTAACATTCAGTCTTTGCTGGAGCAGCTTGGCTGCAATTGCCACGGAGTTAAAATAGCAGAAGCCCATGGGTGTGC
TTTCTTCTGCATGGTGACCTGGAGGCCGAACAACACAAAT
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
1-3
stage 3
Area Pellucida
Primitive Streak
Low level expression.
4-6
stage 4
stage 6
Area Pellucida
Extraembryonic Mesoderm
Headfold
Neural Plate/Tube
Primitive Streak
 
7-12
stage 8
stage 9
stage 9
stage 11
Extraembryonic Blood Vessels
Extraembryonic Mesoderm
Forebrain
Heart
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Primitive Streak
Somites
 
13-18
stage 14
stage 15
stage 15
Eye
Foregut
Head Mesenchyme
Lateral Plate Mesoderm
Liver
Notochord
Pharyngeal Arches and Clefts
Somatic Mesoderm
Somites
Spinal Cord
Trunk Mesenchyme
 
19-23
stage 21
stage 21
stage 21
stage 21
stage 21
stage 23
Endocardium
Extraembryonic
Eye
Gut
Head Mesenchyme
Leg Mesenchyme
Liver
Notochord
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Somites
Wing Mesenchyme
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.3689

Mouse

Emage
EurexpressMGI:3036234
MGI GXDMGI:3036234

Frog

Xenbase488766

Fruit Fly

BDGPFBgn0041210

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-061013-95
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