GEISHA - A Chicken Embryo Gene Expression Database
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HOXA11
homeobox A11

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolHOXA11
Official Full Namehomeobox A11
CGNC ID49268
also known asGHOX1I, chox-1.9, ghox-1I, homeobox protein Hox-A11|Hox A11 variant 1|Hox A11 variant 2|homeo box A11|homeobox protein Hox-1.9|homeodomain-containing protein, Homeobox protein Hox-A11 , Ghox-1I, Chox-1.9
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204619
PolypeptideNP_989950
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.957
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human3207ENSG00000005073MIM:605432MIM:142958
Mouse15396ENSMUSG00000038210All phenotypic alleles (6):Targeted, knock-out(4) Targeted, other(2) MGI:96172
Xenopus100485262, 398250483241
Zebrafish30382, 58061ENSDARG00000009045ZDB-GENE-990415-4, ZDB-GENE-000823-8ZFIN:ZDB-GENE-990415-4, ZFIN:ZDB-GENE-000823-8
Gene Ontology
Molecular Functionsequence-specific DNA binding, sequence-specific DNA binding transcription factor activity
Biological Processanterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, more...cartilage development involved in endochondral bone morphogenesis, developmental growth, dorsal/ventral pattern formation, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic skeletal joint morphogenesis, mesodermal cell fate specification, metanephros development, organ induction, positive regulation of cell development, positive regulation of chondrocyte differentiation, positive regulation of transcription, DNA-templated, proximal/distal pattern formation, transcription, DNA-templated
Cellular Componentcytoplasm, nucleolus, protein-DNA complex, transcription factor complex
Links to other databases
Entrez Gene395327
Ensembl GeneENSGALG00000023130
KEGGgga:395327

Entry 1

GEISHA IdHOXA-11.Reid.2002Data SourcePublication
Complete cDNA Template Probeshow
CTTCTTCAGTGTCTACATAAACAAAGAGAAACGCCTCCAGCTCTCCCGAATGCTCAATCTGACCGACCGCCAAGTAAAA
ATATGGTTTCAAAACAGAAGAATGAAAGAAAAAAAAATTAACAGGGACCGATTACAATATTACTCAGCTAATCCACTAC
TTTAAAACTCGTAGCGTTTTTCAAGACGAGATTAAATTCAGATTTCGCCCTTGACAAGGTCAAGCCACGAGGTTACGTG
GAGGAAGGAGGTGTGTATCTGACGGGACTCGAAGAACCCGAGGTTTTCCGTACATGTAAATCTGCTCTGGACCTTCCGT
GACGGTTTATTGTTTTGTCTATATATTTACGTACCAACTGGAATCGGTTTGATTTTCGCACACGTGGCGTCCATCCATT
TCCACCGCGCGCGTCACCTCCGAGCGCCCGGCCCAACGCCTCTCACCTTCCCGGGCACCGCGGCTCCGGGAGGGGACGG
GGGTGTCCCCGTGTCCCGCTGCCCCC
CitationReid AI, Gaunt SJ. Colinearity and non-colinearity in the expression of Hox genes in developing chick skin. Int J Dev Biol. 2002 Mar
CopyrightCopyright © 2007 UBC Press
CommentsHoxa-11, a ca. 500 base probe extending 3' of nucleotide 55 in the homeobox. This probe was estimated (nt 764-1264) from NM_204619 after mapping the homeobox to nt 709-924 of NM_204619.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 30
Dermis
Leg
Spinal Cord
Surface Ectoderm
 
31-44
stage 44
  

Entry 2

GEISHA IdHOXA11.Mercader.2000Data SourcePublication
Complete cDNA Template Probeshow
GAGAGGCGGAGGCGGCCGGAGAGCGGCAGCAGCCCCGAGTCATCTTCCGGCAACAATGAGGAGAAATCCGGCAGCTCCA
GTGGACAACGGACCCGTAAAAAGAGATGCCCCTACACCAAATATCAGATTAGAGAGCTAGAAAGGGAATTCTTCTTCAG
TGTCTACATAAACAAAGAGAAACGCCTCCAGCTCTCCCGAATGCTCAATCTGACCGACCGCCAAGTAAAAATATGGTTT
CAAAACAGAAGAATGAAAGAAAAAAAAATTAACAGGGACCGATTACAATATTACTCAGCTAATCCACTACTTTAAAACT
CGTAGCGTTTTTCAAGACGAGATTAAATTCAGATTTCGCCCTTGACAAGGTCAAGCCACGAGGTTACGTGGAGGAAGGA
GGTGTGTATCTGACGGGACTCGAAGAACCCGAGGTTTTCCGTACATGTAAATCTGCTCTGGACCTTCCGTGACGGTTTA
TTGTTTTGTCTATATATTTACGTACCAACTGGAATCGGTTTGATTTTCGCACACGTGGCGTCCATCCATTT
CitationMercader N, Leonardo E, Piedra ME, Martínez-A C, Ros MA, Torres M. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development. 2000 Sep;127(18):3961-70.
Copyright© The Company of Biologists Limited 2000
CommentsThe sequence below was obtained from NCBI (acc #:NM_204619.1- Showing 545 bp region from base 616 to 1160) using the information provided in the publication.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-23
stage 22
stage 22
stage 23
stage 23
stage 23
Limb Buds
Stage 22 embryo + 18 hours
Stage 22 embryo + 5 hours
Stage 23 embryo + 24 hours
control embryo = left side

Entry 3

GEISHA IdHoxa-11.Nelson.1996Data SourcePublication
Complete cDNA Template Probeshow
CTCAGCTAATGCGGAGAAGCCGAGGTAGCCCTAATGATGGATTTTGATGAGCGTGTTCCTTGTTCCTCTAACATGTATT
TGCCAAGTTGTACGTACTACGTCTCGGGTCCTGATTTCTCCAGCCTCCCTTCTTTTCTGCCCCAGACCCCGTCTTCTCG
CCCTATGACATACTCCTACTCCTCCAACCTGCCCCAGGTCCAACCCGTGAGAGAAGTGACCTTCAGGGAATATGCCATT
GATCCCTCCAGTAAATGGCACCCCCGGAACAACCTGCCCCACTGCTACTCCGCAGAGGAGATCATGCACAGAGACTGCT
TGCCTTCCACCACCACCGCCAGCATGGGCGAGGTGTTCGGCAAAAGCACCGCGAACGTCTACCACCACCCCAGCGCCAA
CGTCTCCTCCAATTTCTATAGCACGGTGGGCAGGAACGGGGTCCTGCCGCAGGCTTTCGACCAGTTTTTCGAGACGGCG
TACGGCACGGCGGAGAACCCGTCCTCCGCGGACTATCCGCCGGACAAGAGCGGCGAGAAGGCGCCCGCGGCCGCCGGGG
CGACGGCGGCAACTTCAAGTTCGGAGGGCGGCTGCGGCGGGGCGGCGGCGGCGGCGGGGAAGGAGAGGCGGAGGCGGCC
GGAGAGCGGCAGCAGCCCCGAGTCATCTTCCGGCAACAATGAGGAGAAATCCGGCAGCTCCAGTGGACAACGGACCCGT
AAAAAGAGATGCCCCTACACCAAATATCAGATTAGAGAGCTAGAAAGGGAATTCTTCTTCAGTGTCTACATAAACAAAG
AGAAACGCCTCCAGCTCTCCCGAATGCTCAATCTGACCGACCGCCAAGTAAAAATATGGTTTCAAAACAGAAGAATGAA
AGAAAAAAAAATTAACAGGGACCGATTACAATATTACTCAGCTAATCCACTACTTTAAAACTCGTAGCGTTTTTCAAGA
CGAGATTAAATTCAGATTTCGCCCTTGACAAGGTCAAGCCACGAGGTTACGTGGAGGAAGGAGGTGTGTATCTGACGGG
ACTCGAAGAACCCGAGGTTTTCCGTACATGTAAATCTGCTCTGGACCTTCCGTGACGGTTTATTGTTTTGTCTATATAT
TTACGTACCAACTGGAATCGGTTTGATTTTCGCACACGTGGCGTCCATCCATTTCCACCGCGCGCGTCACCTCCGAGCG
CCCGGCCCAACGCCTCTCACCTTCCCGGGCACCGCGGCTCCGGGAGGGGACGGGGGTGTCCCCGTGTCCCGCTGCCCCC
TCGGAGCGTGGCGTGGGCACCGGCACCGCGAGCGGCCGCAGCCGGGACGCAAACTTTGGGAAACGATCTCTCTTCCTTC
CCGGAGGAAAAACGTCTGTGGTTGAGGCAGTGCGCCATTGCCCATGGGTTTGAAAGGGGAATTAAGGGAGGGGGGAGAG
AAGTAAAGGGGAGGGGGGGGGGGGGCGACGTGCCTACACCTTCACGAGGCCGACCACGAGCAGTTGTAACGTGGATGTA
GCGATGGGTACGATAGTGTTTCCTTTGGGGTGGGAGGAAGCGGGGAAGGGGGTGGGAAGAGAAAGAACCGAAAGACTGA
AATATTTACTTTAAAAAGAAAAAAAAATCAGGTATAAATTTTGCCATACATCGCAAGGAAACAATCACTGAAAAGGCAA
AGAAAAGAAAAACAAAGCGAAGATTTCTCCAGTTGTAACTAGCTCTCGTTTTATTTATGACAACGGCCTGCGCGTTGCC
ATCTTTTCGGAGACAAATCATATTTAAATGCTAAAAATAAAGCGTCAAAGGGGGGGAAAAAAAAGAAGTGTGAATTTCA
GCGTTTTTAAAGAAAAAAAAATAAGGAGAGGAAACGAACCTCCCGGCTTCTGGCTCGCAAACTTTCTTCAGGAAATACC
TGTGGAGAACGACAGTTTAGCAAATACCACACAACACTTAATTGAAACTTGGAGTTGTGCAATGCGCTAACGTTGGGTC
ATTAAAATAACTCAATCGCATGCTCTTGTAAAGGTGACCAGTGAGGAGTCGAATCAGAAGCCAAACAGTGTAAATACGG
TCGTTTTGTTGTCGTCTACTTTAAATGTCACGAGCTCTACTTTGTCGCCCAGCCGACGTATGCAAAGAACGGAGAGTTG
TTCGGAGTTATTTTAAGTATCTATAAATATATATATTTCCCTGCAGGAACCAAAGCGTGAAAAAATAAAAAAAAAAAAA
CitationNelson CE, Morgan BA, Burke AC, Laufer E, DiMambro E, Murtaugh LC, Gonzales E, Tessarollo L, Parada LF, Tabin C. Analysis of Hox gene expression in the chick limb bud. Development. 1996 May;122(5):1449-66.
CopyrightCopyright © 1996 by Company of Biologists
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204619 ).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 19
stage 19
stage 23
stage 23
Leg
Wing
 
25-30
stage 25
stage 25
stage 25
stage 28
stage 28
Leg
Wing
 
31-44
stage 44
stage 44
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.957

Mouse

EmageMGI:96172
EurexpressMGI:96172
MGI GXDMGI:96172

Frog

Xenbase483241

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-990415-4, ZDB-GENE-000823-8
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