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 | JAK2
Janus kinase 2 | The human orthologue of this gene is associated
with the following human diseases: |
| Gene | | Official Symbol | JAK2 | | Official Full Name | Janus kinase 2 | | CGNC ID | 11173 | | also known as | JAK-2, tyrosine-protein kinase JAK2|Janus kinase 2 (a protein tyrosine kinase)|tyrosine kinase | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | ATP binding, heme binding, histone binding, histone kinase activity (H3-Y41 specific), more...non-membrane spanning protein tyrosine kinase activity, protein tyrosine kinase activity | | Biological Process | activation of JAK2 kinase activity, cytokine-mediated signaling pathway, erythrocyte differentiation, more...histone H3-Y41 phosphorylation, JAK-STAT cascade involved in growth hormone signaling pathway, protein autophosphorylation, signal transduction | | Cellular Component | cytoskeleton, endomembrane system, membrane, nucleus |
| | Links to other databases | |
Entry 1| GEISHA Id | JAK2.UApcr | Data Source | GEISHA ISH Analysis | | Forward cDNA Template Primer | TCTGAGTCCTTCTTTGAGGCAGC | | Reverse cDNA Template Primer | AATTAACCCTCACTAAAGGTTATCCTGTAGGGGGTCATACCG | cDNA Template Length | 851 | | Forward cDNA Template Probe | show CTCAACACCGGCCAAAGTTTCCCTTGCCAAGGTTGCTGTAAAAACTTAAGAATGTCTTTCTTCAAATTGTGTTGGGTCC
CGATCTTCAAAGGCCCCAGAAAATCCAAGAGCTCCAGTTCGTATATTTGGCAACATATCATTTTCTGTCAATAACTCAT
AATCAGGAGTGAACAAACTATTCAAGTCACGTATAATTGCCCTAAATGACGGCCTGAAATCTGGCTCATAATCCATACA
GTTGTTTATAAGGTTTGCTAGCTCTGTCCAGTTGGGGGCAGGAAGCTGGTGTCTATCTTCATAAAACTGTAGTTTTCTT
GAAGAATCGAGAGCACTCAGTGGTTTGTCTCCTCCACTGCAGATTTCCCATAAAGTGGTACCAAAACTCCACTTATCTG
TAGCTAGGCTTAGTTGTCTGGGGTTCTCAATACATTCAGGTGGAACCCATGGTATTCTCTCAAGAAGAATATCTCTTGG
CAAAACTGTGATACTGATGCCAGGGTCACTTAGTTTTATAAAAGGAAGGTTTCCAGACTTCCTGTCCTCCTCCCTGATA
AGCAAGATGTTCTTTGCACAGACATTCCCATGAACAAGGCCTTTATCCTCCAGGAAATGCATGGCTAGTGCCAACTGTT
TGGCAACTTCCAGCTTCCACAAGATATTA |
Entry 2| GEISHA Id | JAK2.Tao.2020 | Data Source | Publication | | Complete cDNA Template Probe | show CAGAGGCACAATGTCAGCCAGATGGTCTTTCACAAAATCCGGAATGAGGACTTGATTTTTGAAGAGAGTCTTGGGCAGG
GCACATTTACAAAGATTTTCAAAGGCATAAGGAAAGAAGTGGGAGACTACGGCCAGCTTCACCAAACTGAAGTTCTTTT
AAAGGTTTTGGATAAAGTGCATAGAAACTACTCTGAGTCCTTCTTTGAGGCAGCAAGTATGATGAGCCAGCTTTCTTAC
AAACATTTGGTATTAAATTATGGAGTCTGTGTGTGTGGAGAGGAGAATATCCTTGTACAAGAGTATGTGAAATTTGGAT
CTTTGGACACATATTTGAAAAAGAACAAAAACGTTATTAATATCTTGTGGAAGCTGGAAGTTGCCAAACAGTTGGCACT
AGCCATGCATTTCCTGGAGGATAAAGGCCTTGTTCATGGGAATGTCTGTGCAAAGAACATCTTGCTTATCAGGGAGGAG
GACAGGAAGTCTGGAAACCTTCCTTTTATAAAACTAAGTGACCCTGGCATCAGTATCACAGTTTTGCCAAGAGATATTC
TTCTTGAGAGAATACCATGGGTTCCACCTGAATGTATTGAGAACCCCAGACAACTAAGCCTAGCTACAGATAAGTGGAG
TTTTGGTACCACTTTATGGGAAATCTGCAGTGGAGGAGACAAACCACTGAGTG | | Citation | Tao Y, Zhou X, Liu Z, Zhang X, Nie Y, Zheng X, Li S, Hu X, Yang G, Zhao Q, Mou C.. Expression patterns of three JAK–STAT pathway genes in feather follicle development during chicken embryogenesis. Gene Expr Patterns. 2020 Jan;35:119078. doi: 10.1016/j.gep.2019.119078. Epub 2019 Nov 20. | | Copyright | Copyright © 2020 Elsevier B.V. or its licensors or contributors. | | Comments | The complete cDNA template sequence was obtained from the information from the publication as described in Tao et al. 2020. |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 25-30 |  | | stage 28 |
 | | stage 28 |
 | | stage 30 |
 | | stage 30 |
| Unlabeled
| | 31-36 |  | | stage 34 |
 | | stage 34 |
 | | stage 34 |
 | | stage 34 |
 | | stage 35 |
 | | stage 35 |
 | | stage 35 |
 | | stage 35 |
 | | stage 36 |
 | | stage 36 |
 | | stage 36 |
 | | stage 36 |
| Feathers/Scutae
| | all | | |
| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.954 |
MouseFrogFruit FlyZebra FinchZebrafish |
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