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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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LINGO1
leucine rich repeat and Ig domain containing 1

Gene

Official Symbol	LINGO1
Official Full Name	leucine rich repeat and Ig domain containing 1
CGNC ID	1953
also known as	LINGO-1, LRRN6A, leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1\|cLINGO-1\|leucine rich repeat neuronal 6A, leucine rich repeat neuronal 6A, LINGO-1, LRRN6A
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001024577
Polypeptide	NP_001019748
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.13113

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	84894	ENSG00000169783		MIM:609791
Mouse	235402	ENSMUSG00000049556	All phenotypic alleles (4):Targeted, knock-out(2) Targeted, other(2)	MGI:1915522
Xenopus	100101739			921956
Zebrafish	564943, 447837	ENSDARG00000035899	ZDB-GENE-080327-16, ZDB-GENE-040912-136	ZFIN:ZDB-GENE-080327-16, ZFIN:ZDB-GENE-040912-136

Gene Ontology

Molecular Function	epidermal growth factor receptor binding
Biological Process	central nervous system neuron development, negative regulation of oligodendrocyte differentiation, more...
Cellular Component	integral component of membrane, plasma membrane

Links to other databases

Entrez Gene	415344
Ensembl Gene
KEGG	gga:415344

Entry 1

GEISHA Id	LINGO-1.Okafuji.2005	Data Source	Publication
Complete cDNA Template Probe	show CTGCAGGAGATCCAGCTGGTGGGAGGGCAGCTCACCACGGTCGAGCCCTTTGCCTTCCGTGGCCTCAATTACCTGCGCA TCCTGAACGTGTCAGGAAACTTGCTGACCACTCTGGAAGAGTCGGCCTTCCACTCGGTGGGCAACCTGGAGACGCTCAT CCTCGACAACAACCCCTTGGCCTGCGACTGTCGGCTGCTGTGGGTGTTCCGACGGCGATGGAGGTTGAACTTCAATAAG CAGCAGCCCACCTGCTCTACCCCCGAGTTCGTCCAGGGCAAGGAGTTCAAAGACTTCCCTGACGTCCTCCTGCCCAACT ACTTCACCTGCCGCCGAGCTCGGATACGGGACCGCAAACCTCAGCAGATCTTTGTGGACGAAGGCCACACGGTGCATTT TGTCTGTCGGGCAGACGGGGATCCGCCACCCGCCATCATGTGGCTCTCTCCCCGGAAGCACCTCATCTCCACCAAAACC AACGGGCGGCTCACTGTCTTCCCTGACGGCACGCTGGAGGTGCGCTACGCCCAGATCCAGGACAACGGCACCTACCTAT GCATTGCCAGCAACGCGGGTGGCAACGACACCATGCTGGCCCACCTGCACGTGCGCAGCTACTCCCCAGACTGGCCCCA CCAGCCCAACAAGACCTTCGCGTTCATCTCCAACCAGCCCAACGAGAGCGATGCCAACAGCACACGTGCCACCGTGCCT TTTCCCTTTGACATCAAGACTCTCATCATCGCCACCACCATGGGCTTCATTTCTTTCCTGGGCGTCGTGCTCTTCTGTC TGGTGCTCCTCTTCCTGTGGAGCCGGGGGAAAGGCAACACCAAGCACAACATTGAAATCGAGTACGTGCCACGCAAGTC CGACGCGGGCATCAGCTCTGCCGACGCACCGCGCAAATTCAATATGAAGATGATTTAACCAGGCAACAATTTG
Citation	Okafuji T, Tanaka H. Expression pattern of LINGO-1 in the developing nervous system of the chick embryo. Gene Expr Patterns. 2005 Dec;6(1):57-62. Epub 2005 Jul 18.
Copyright	Reprinted with permission from Elsevier. Copyright © 2005 Elsevier B.V. All rights reserved.
Comments	The template for the cLINGO-1 probe was a 942-bp fragment coding 3′ of ORF (1287-2228). The sequence for this was extracted from Acc# NM_001024577.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 9

stage 12

Eye
Forebrain
Hindbrain
Midbrain
Telencephalon

13-18

stage 17

Cranial Nerve
Hindbrain
Midbrain
Retina
Telencephalon

facial nerve
trigeminal nerve

19-24

stage 19

stage 23

Forebrain
Hindbrain
Midbrain
Spinal Cord
Spinal Ganglia and Nerves

cerebellum

25-28

stage 25

stage 27

stage 28

Spinal Cord
Spinal Ganglia and Nerves

Entry 2

GEISHA Id	LINGO1.Anderson.2021	Data Source	Direct Submission
Complete cDNA Template Probe	show CTCATTACCTGCGCATCCTGAACGTGTCAGGAAACTTGCTGACCACTCTGGAAGAGTCGGCCTTCCACTCGGTGGGCAA CCTGGAGACGCTCATCCTCGACAACAACCCCTTGGCCTGCGACTGTCGGCTGCTGTGGGTGTTCCGACGGCGATGGAGG TTGAACTTCAATAAGCAGCAGCCCACCTGCTCTACCCCCGAGTTCGTCCAGGGCAAGGAGTTCAAAGACTTCCCTGACG TCCTCCTGCCCAACTACTTCACCTGCCGCCGAGCTCGGATACGGGACCGCAAACCTCAGCAGATCTTTGTGGACGAAGG CCACACGGTGCATTTTGTCTGTCGGGCAGACGGGGATCCGCCACCCGCCATCATGTGGCTCTCTCCCCGGAAGCACCTC ATCTCCACCAAAACCAACGGGCGGCTCACTGTCTTCCCTGACGGCACGCTGGAGGTGCGCTACGCCCAGATCCAGGACA ACGGCACCTACCTATGCATTGCCAGCAACGCGGGTGGCAACGACACCATGCTGGCCCACCTGCACGTGCGCAGCTACTC CCCAGACTGGCCCCACCAGCCCAACAAGACCTTCGCGTTCATCTCCAACCAGCCCAACGAGAGCGATGCCAACAGCACA CGTGCCACCGTGCCTTTTCCCTTTGACATCAAGACTCTCATCATCGCCACCACCATGGGCTTCATTTCTTTCCTGGGCG TCGTGCTCTTCTGTCTGGTGCTCCTCTTCCTGTGGAGCCGGGGGAAAGGCAACACCAAGCACAACATTGAAATCGAGTA CGTGCCACGCAAGTCCGACGCGGGCATCAGCTCTGCCGACGCACCGCGCAAATTCAATATGAAGATGATTTAACCAGGC AACAATTTGCAAATAGTTTTGGGGTTTTGTTTTTTGNTTTTTNTTNTTTAAACAAANGAGAACCTAATGAACAAATAAA
Comments	Images and probe sequence provided by Claire Anderson. The probe was synthesized from cDNA clone ChEST905c4. Related paper: Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 12

Dermomyotome
Ear/Otic Placode
Eye
Forebrain
Foregut
Gut
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Somatic Mesoderm
Splanchnic Mesoderm

section 32
section 43

Entry 3

GEISHA Id	LINGO1.Anderson.2019	Data Source	Publication
Complete cDNA Template Probe	show CTCAATTACCTGCGCATCCTGAACGTGTCAGGAAACTTGCTGACCACTCTGGAAGAGTCGGCCTTCCACTCGGTGGGCA ACCTGGAGACGCTCATCCTCGACAACAACCCCTTGGCCTGCGACTGTCGGCTGCTGTGGGTGTTCCGACGGCGATGGAG GTTGAACTTCAATAAGCAGCAGCCCACCTGCTCTACCCCCGAGTTCGTCCAGGCAAGGAGTTCAAAGACTTCCCTGACG TCCTCCTGCCCAACTACTTCACCTGCCGCCGAGCTCGGATACGGGACCGCAAACCTCAGCAGATCTTTGTGGACGAAGG CCACACGGTGCATTTTGTCTGTCGGGCAGACGGGGATCCGCCACCCGCCATCATGTGGCTCTCTCCCCGGAAGCACCTC ATCTCCACCAAAACCAACGGGCGGCTCACTGTCTTCCCTGACGGCACGCTGGAGGTGCGCTACGCCCAGATCCAGGACA ACGGCACCTACCTATGCATTGCCAGCAACGCGGGTGGCAACGACACCATGCTGGCCCACCTGCACGTGCGCAGCTACTC CCCAGACTGGCCCCACCAGCCCAACAAGACCTTCGCGTTCATCTCCAACCAGCCCAACGAGAGCGATGCCAACAGCACA CGTGCCACCGTGCCTTTTCCCTTTGACATCAAGACTCTCATCATCGCCACCACCATGGGCTTCATTTCTTTCCTGGGCG TCGTGCTCTTCTGTCTGGTGCTCCTCTTCCTGTGGAGCCGGGGGAAAGGCACACCAAGCACAACCATTGAAATCGAGTA CGTGCCACGCAAGTCC
Citation	Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Copyright	Copyright © 2019 Elsevier Inc. All rights reserved.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Anderson et al. 2019.