GEISHA - A Chicken Embryo Gene Expression Database
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MBNL1
muscleblind like splicing regulator 1

Gene
Official SymbolMBNL1
Official Full Namemuscleblind like splicing regulator 1
CGNC ID52321
also known asmuscleblind-like protein 1|muscleblind-like 1
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001031322
PolypeptideNP_001026493
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.4840
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly36945FBgn0261642
Human4154ENSG00000152601MIM:606516
Mouse56758ENSMUSG00000027763All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2) MGI:1928482
Xenopus1004986486035556
Zebrafish767696ZDB-GENE-060929-704ZFIN:ZDB-GENE-060929-704
Gene Ontology
Molecular Functionmetal ion binding, RNA binding
Biological ProcessmRNA processing, RNA splicing
Cellular Componentcytoplasm, nucleus
Links to other databases
Entrez Gene425033
Ensembl GeneENSGALG00000010361
KEGGgga:425033

Entry 1

GEISHA IdMBNL1.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerAACCCCCTCAGCAGTAAGACATC
Reverse cDNA Template PrimerAATTAACCCTCACTAAAGGCTACGCTAATCAACACCTCCGCcDNA Template Length944
Forward cDNA Template Probeshow
TTTGGTTCGTCATGCATCTGACCCAGTGCTTCTGCCGCCTTAGTTTAGAGTCACCAGTTAAGGCGTGACTGTGCGAAGG
GAAGGCGCAGCCCGTCTGCAGAGCGTTTAGAGTCCTTTGACTTCTGACAGAGGCTGTGCAGAGAAGCAGAAGTAGTTCC
TCAGACATTTGTCGCCGCGTCTCAGAAATGGCTTTTCCCTTTCCGGCAGCACAGCGAGCGCCATTTCTGAGACGGCTTT
GGTTTGGAAACAGAACGGTGCCCTTTGACTGATCGGTACGAGCAAGGTAAGCGAAAACGTGGTTCTGAAAATAACACTG
CAAAATAACACTCTGGTCTGCTGTACAGTCTATGGCACTTCATGAGAATCCGTAACAATGTGGTACTTAAAGCCATCGA
CGTGCTTTAAAATAGACACGGTTGTGGTTTTGCTTGGCACATTCATCTCTGTCAGATACCTCTCTTACCGCTTCTTACA
ATCCATTACATTAAAAATATTACTCTTAAACAAAAATTACTGTGCATGCACGCTCTCATCTATAATGGCAATTTTAAAT
ACAAGGTGCACCTTTGTTATTTGTAAACCTTGAAAGAAATAAACTTACTTTAAAAAATTATATCTTGGTCTACAGACGT
ACCAATACATAATAGATTCATGGTTACACCATAGTCTGTCTTTTCAAGGTGACATACACGGTTATGTAGGAAATTGGCC
GCACACGCGAATCCGAGCGCGTACGCGCGCTCCTGCGCTAGAAAAGATAGACAATGTTGTAGTTCTTAGACAAGAAGAT
CACCTCAGCACAAATATCAATTAAATGTACAAAGTATATAGGCAACAGTGTGCAGTGGATTCCCAAGTTCTCGTTCGTC
TCCTTAACATGCAATGGTGTGGATGTCTTACTG
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 5
Unlabeled
 
7-12
stage 8
stage 9
stage 11
stage 11
Anterior Intestinal Portal
Blood Islands
Extraembryonic Mesoderm
Forebrain
Heart
Hindbrain
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
 
13-18
stage 15
stage 15
stage 15
stage 16
Blood Islands
Dermomyotome
Eye
Head Mesenchyme
Heart
Hindbrain
Intermediate Mesoderm
Midbrain
Myotome
Neural Plate/Tube
Notochord
Pharyngeal Arches and Clefts
Sinus Venosus
Somites
Yolk Sack or Stalk
 
19-24
stage 20
stage 20
stage 20
stage 20
Allantois
Ear/Otic Placode
Eye
Foregut
Head Mesenchyme
Leg Mesenchyme
Liver
Lung
Nasal Placode/Nerve
Notochord
Pharyngeal Arches and Clefts
Sclerotome
Wing Mesenchyme
 
25-26
stage 26
stage 26
stage 26
stage 26
Foregut
Leg Mesenchyme
Liver
Lung
Mesonephros
Nasal Placode/Nerve
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Tail
Ventricles
Wing Mesenchyme
 

Entry 2

GEISHA IdMBNL1.Vajda.2009Data SourcePublication
Complete cDNA Template Probeshow
ATGGCCGTCAGCGTCACGCCCATCCGCGACACCAAGTGGCTCACGCTGGAGGTGTGCCGGGAGTTCCAGAGGGGGACGT
GCTCACGGCCGGACACGGAATGTAAATTTGCACACCCGTCGAAAAGCTGCCAGGTGGAGAACGGACGTGTCATCGCCTG
CTTCGACTCATTGAAAGGGCGATGTTCGAGGGAGAACTGCAAGTACCTTCACCCGCCGCCGCACTTAAAAACGCAGCTG
GAGATCAATGGCCGCAATAACCTGATCCAGCAGAAGAACATGGCCATGCTGGCCCAGCAGATGCAGCTTGCCAATGCCA
TGATGCCCGGAGCCCCGCTGCAGCCTGTGCCCATGTTCTCCGTTGCGCCCAGCCTAGCCACCAATGCCTCGGCTGCCTT
CAACCCCTACCTGGGGCCCGTGTCCCCAGGGCTGGTGCCGGCGGAGATCCTGCCCACCGCGCCCATGCTGGTGGCGGGC
AACCCTGGTGTCCCGGTGCCTGCTGCCGCCGCTGCTGCTGCGCAGAAGCTGATGAGGACGGACAGGCTGGAGGTGTGTC
GGGAGTACCAACGCGGGAACTGCAACCGGGGCGAGAACGACTGCCGGTTCGCTCACCCCGCCGACAGCGCCATGATCGA
CACCAACGATAACACCGTTACGGTCTGCATGGATTACATCAAAGGGAGATGCTCACGGGAAAAGTGCAAATACTTCCAC
CCTCCAGCACATCTGCAAGCCAAGATCAAGGCTGCCCAGTACCAGGTTAACCAGGCTGCAGCTGCCCAGGCAGCAGCGA
CGGCGGCTGCCATGACTCAGTCGGCTGTCAAATCACTGAAGCGACCCCTCGAGGCAACCTTTGACCTGGGAATTCCTCA
AGCTGTACTTCCCCCATTACCAAAGAGGCCTGCGCTTGAAAAAACCAATGGTGCCACCGCAGTGTTCAATACTGGTATT
TTCCAATACCAGCAAGCTCTTGCCAACATGCAGCTGCAGCAGCACACAGCCTTTCTCCCACCAGGCTCAATATTGTGCA
TGACACCCGCTACAAGTGTTGTTCCCATGGTGCACGGTGCTACGCCAGCCACTGTGTCTGCAGCAACAACATCTGCCAC
AAGTGTTCCCTTCGCTGCAACAGCCACAGCCAACCAGATACCCATAATATCTGCCGAACATCTGACTAGCCACAAGTAT
GTTACACAGATGTAG
CitationVajda NA, Brimacombe KR, LeMasters KE, Ladd AN. Muscleblind-like 1 is a negative regulator of TGF-β-dependent epithelial-mesenchymal transition of atrioventricular canal endocardial cells. Dev Dyn. 2009 December; 238(12): 3266–3272.
CopyrightCopyright © 2009 Wiley-Liss, Inc.
CommentsThe probe was amplified by PCR using the following primers: 5_-ATGGCCGTCAGCGTCACGCCCATC-3_ and 5_-CTACA TCTGTGTAACATACTTGTG-3_ and was extracted from NCBI Acc# NM_001163324.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 14
stage 18
stage 18
Limb Buds
Myocardium
Valves
Ventricles
 
19-23
stage 23
stage 23
Atria
Myocardium
Valves
Ventricles
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.4840

Mouse

EmageMGI:1928482
EurexpressMGI:1928482
MGI GXDMGI:1928482

Frog

Xenbase6035556

Fruit Fly

BDGPFBgn0261642

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-060929-704
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