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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow

The human orthologue of this gene is associated
with the following human disease:

Cardiomyopathy, familial hypertrophic, 8

Gene

Official Symbol	MYL3
Official Full Name	myosin, light chain 3, alkali; ventricular, skeletal, slow
CGNC ID	49636
also known as	MLC, MLC1c/1s, myosin light chain 1, cardiac muscle\|cardiac muscle\|light polypeptide 3\|myosin alkali light chain\|myosin light chain A1\|myosin light chain alkali 1\|myosin, light polypeptide 3, alkali; ventricular, skeletal, slow\|slow skeletal ventricular myosin alkali light chain 3
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205159
Polypeptide	NP_990490
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4198

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	4634	ENSG00000160808	MIM:608751	MIM:160790
Mouse	17897	ENSMUSG00000059741	All phenotypic alleles (2):Targeted, other(2)	MGI:97268
Xenopus	394608, 398607, 398606, 100124786, 373844			946569, 977610
Zebrafish	100148520, 574004	ENSDARG00000011519	ZDB-GENE-050626-112	ZFIN:ZDB-GENE-050626-112

Gene Ontology

Molecular Function	calcium ion binding
Biological Process
Cellular Component	myosin complex

Links to other databases

Entrez Gene	396067
Ensembl Gene	ENSGALG00000005448
KEGG	gga:396067

Entry 1

GEISHA Id	MYL3.Anderson.2022	Data Source	Publication
Complete cDNA Template Probe	show CTCTTGCCTGTCTGTGCCCTTCTTTCCAAAAGCAGCCCACCAGCAAGCACCATGCCTCCAAAGAAGCCTGAACCTAAGA AGGCGCCTGAACCCAAGAAGGAAGAACCCAAACCAGCACCTAAGCCAGCAGAACCAGAGCCCAAAAAAGAAGTTGAATT TAACCCAGCTTCTATCAAAGTTGAATTCACCCCTGATCAGATTGAAGAATTTAAGGAAGCGTTCTCACTTTTTGACCGT ACTCCCAAATCTGAGATGAAGATCACATATGCGCAATGTGGAGATGTCTTGAGGGCTTTGGGGCAGAATCCAACCCAGG CTGAGGTCATGAAGGTGCTTGGCAGACCCAAACAAGAAGAGATGAACTCCAAGATGATTGACTTTGAGACCTTCCTGCC CATGCTCCAGCACATTTCCAAGACAAAAGACACAGGCACCTACGAGGACTTTGTGGAAGGTCTGCGTGTGTTTGACAAG GAGGGAAATGGAACAGTGATGGGGGCTGAACTTCGCCATGTTCTGGCTACGCTGGGTGAAAGGTTGACTGAAGAGGAAG TTGATAAGCTAATGGCTGGCCAGGAAGATGCCAATGGTTGTATCAACTATGAAGCTTTTGTGAAACATATCATGGCTAA CTGAACACCAGCTTTGGAAGACACCACCTTTAACATGTGAGATGTAACGGATGAACAACACAAAACAAAGGTGAATGCT TTACTGCTAGAATGCATCCCTTCTCTCTGTTCTCCAAAAGGATATATTCTCCTTTTAACAGTCTGGTCTATGACAAATG AACTGTTTTATTTTTCCCAATGAAAACTTGAAATTGTTCCATTATGTATTTCCTGGCCCTGTTTTTCTTGCAGTAAAAC ATGGGATTCTTTGGCAAAAA
Citation	Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Copyright	Copyright © 2019 Elsevier Inc. All rights reserved.
Comments	Images and probe sequence provided by Claire Anderson. The probe was synthesized from cDNA clone ChEST220a4. Related paper: Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Extraembryonic Mesoderm
Lateral Plate Mesoderm

7-12

stage 7

stage 8

stage 9

stage 10

stage 12

Atria
Extraembryonic Mesoderm
Outflow Tract
Ventricles

Entry 2

GEISHA Id	MYL3.Anderson.2019	Data Source	Publication
Complete cDNA Template Probe	show CTCTTGCCTGTCTGTGCCCTTCTTTCCAAAAGCAGCCCACCAGCAAGCACCATGCCTCCAAAGAAGCCTGAACCTAAGA AGGCGCCTGAACCCAAGAAGGAAGAACCCAAACCAGCACCTAAGCCAGCAGAACCAGAGCCCAAAAAAGAAGTTGAATT TAACCCAGCTTCTATCAAAGTTGAATTCACCCCTGATCAGATTGAAGAATTTAAGGAAGCGTTCTCACTTTTTGACCGT ACTCCCAAATCTGAGATGAAGATCACATATGCGCAATGTGGAGATGTCTTGAGGGCTTTGGGGCAGAATCCAACCCAGG CTGAGGTCATGAAGGTGCTTGGCAGACCCAAACAAGAAGAGATGAACTCCAAGATGATTGACTTTGAGACCTTCCTGCC CATGCTCCAGCACATTTCCAAGACAAAAGACACAGGCACCTACGAGGACTTTGTGGAAGGTCTGCGTGTGTTTGACAAG GAGGGAAATGGAACAGTGATGGGGGCTGAACTTCGCCATGTTCTGGCTACGCTGGGTGAAAGGTTGACTGAAGAGGAAG TTGATAAGCTAATGGCTGGCCAGGAAGATGCCAATGGTTGTATCAACTATGAAGCTTTTGTGAAACATATCATGGCTAA CTGAACACCAGCTTTGGAAGACACCACCTTTAACATGTGAGATGTAACGGATGAACAACACAAAACAAAGGTGAATGCT TTACTGCTAGAATGCATCCCTTCTCTCTGTTCTCCAAAAGGATATATTCTCCTTTTAACAGTCTGGTCTATGACAAATG AACTGTTTTATTTTTCCCAATGAAAACTTGAAATTGTTCCATTATGTATTTCCTGGCCCTGTTTTTCTTGCAGTAAAAC ATGGGATTCTTTGGCAAAAA
Citation	Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Copyright	Copyright © 2019 Elsevier Inc. All rights reserved.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Anderson et al. 2019.