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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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MITF
melanogenesis associated transcription factor

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	MITF
Official Full Name	melanogenesis associated transcription factor
CGNC ID	49531
also known as	CMI9, microphthalmia-associated transcription factor, Mitf, microphthalmia-associated transcription factor
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_205029
Polypeptide	NP_990360

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	4286	ENSG00000187098	MIM:103500	MIM:156845
Mouse	17342	ENSMUSG00000035158	All phenotypic alleles (31):Targeted, other(5) Transgenic(2) Spontaneous(13) Chemically induced(7) Radiation induced(3) Other(1)	MGI:104554
Xenopus	100101790, 373794, 100337579			484961
Zebrafish	100332720, 30080, 114833	ENSDARG00000003732, ENSDARG00000037833	ZDB-GENE-990910-11, ZDB-GENE-010919-1	ZFIN:ZDB-GENE-990910-11, ZFIN:ZDB-GENE-010919-1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	395886
Ensembl Gene
KEGG	gga:395886

Entry 1

GEISHA Id	ChEST504n18	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show TGTGGGCGTGCGGGAGCTGAGCGGCTCCGAGCGGCGCGGCGGTCACCTCGCGGCTCTCCTCTCGCGGCGGCGACGATGC AGGCGGAGTCGGGGATCGTGCCGGACTTCGAGGTGGGCGAGGAGTTCCACGAGGAGCCCAAGACGTACTACGAGCTGAA GAGTCAGCCCCTCAAGAGCAGCAATTCCGAGCATCCTGGCGCTTCCAAGCCTCCCTTAAGCTCCTCCAGCATGACCTCA CGAATCCTGCTACGGCAGCAGCTCATGCGTGAGCAGATGCAGGAGCAGGAGCGTCGGGAGCAGCAGCAGAAGCAGCAAG CAGCCCAGTTCATGCAACAGAGAGTTCCCGTCAGCCAGACACCTGCCATCAACGTCAGCGTGCCCGCCAGCCTGCCCCC TGCCACGCAGGTACCCATGGAGGTCCTCAAGGTGCAGACTCACCTTGAGAATCCAACCAAATACCATATTCAGCAAGCT CAGCGGCAGCAGGTAAAGCAGTACCTCTCTACCACTCTAGCAAATAAACACGCCAACCAAGCCCTGAGCTTGCCATGTC CAAACCAGCCCGGTGATCATGTCATGCCGCCTGGAACTGGAAGCAGTGCGCCCAACAGTCCGATGGCTATGCTCACCCT CAACTCCAACTGTG

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 6

Extraembryonic
Surface Ectoderm

7-12

stage 11

Extraembryonic

13-18

stage 13

stage 16

stage 17

Blood Vessels
Extraembryonic
Head Mesenchyme
Lateral Plate Mesoderm
Paraxial Mesoderm
Surface Ectoderm

19-21

stage 19

stage 21

Amnion
Lateral Plate Mesoderm
Limb Buds
Paraxial Mesoderm
Pharyngeal Arches and Clefts
Surface Ectoderm
Widespread Expression

Entry 2

GEISHA Id	Mitf.Canto-Soler.2006	Data Source	Publication
Complete cDNA Template Probe	show GGATTCTGCTCTGCGGTTCTGCAAACCCTGAGAGCAATGGAGCCCCTGGTAGAAGCTGAGCCGTCTCTCTCTGCTCTTC CCACAGCAATTCCGAGCATCCTGGCGCTTCCAAGCCTCCCTTAAGCTCCTCCAGCATGACCTCACGAATCCTGCTACGG CAGCAGCTCATGCGTGAGCAGATGCAGGAGCAGGAGCGTCGGGAGCAGCAGCAGAAGCAGCAAGCAGCCCAGTTCATGC AACAGAGAGTTCCCGTCAGCCAGACACCTGCCATCAACGTCAGCGTGCCCGCCAGCCTGCCCCCTGCCACGCAGGTACC CATGGAGGTCCTCAAGGTGCAGACTCACCTTGAGAATCCAACCAAATACCATATTCAGCAAGCTCAGCGGCAGCAGGTA AAGCAGTACCTCTCTACCACTCTAGCAAATAAACACGCCAACCAAGCCCTGAGCTTGCCATGTCCAAACCAGCCCGGTG ATCATGTCATGCCGCCTGGAACTGGAAGCAGTGCGCCCAACAGTCCGATGGCTATGCTCACCCTCAACTCCAACTGTGA AAAAGAGGGATTTTATAAATTTGAAGAGCAAAGCAGGGTCGAGAGTGAGTGCCCGGCTCTGAATACCCACTCACGAGCA TCATGCATGCAGATGGATGATGTGATTGATGACATAATTAGTCTGGAATCAAGTTACAATGAAGAAATCCTTGGCTTGA TGGACCCAGCCTTGCAAATGGCAAATACGTTACCAGTGTCTGGGAATTTGATTGACCTTTATGGCAACCAAAGCATGCC TCCTCCAGGACTTAACATCAGCAACTCCTGTCCAGCTAATCTTCCTAATATAAAAAGGGAGCTCACAGAGTCAGAAGCG AGAGCACTGGCTAAGGAGAGGCAAAAGAAAGACAATCACAACTTGATTGAACGAAGAAGAAGATTTAATATTAATGACC GTATAAAAGAACTGGGCACCTTGATACCCAAATCAAACGACCCGGATATGCGCTGGAATAAGGGAACTATTCTAAAAGC ATCAGTGGACTACATCCGTAAGCTGCAAAGAGAGCAGCAACGCACGAAGGAACTTGAGAACAGACAGAAGAAATTGGAA CACGCCAACAGGCACCTGCTGCTCAGAATACAGGAACTTGAGATGCAAGCTCGGGCACATGGACTGTCCCTTGTTCCAT CCACAGGCATTTGCTCCCCTGATATGGTCAACAGGGTCATCAAACAAGAACCTGTGCTGGACAACTGCAACCAAGACCT CATGCCGCACCACACAGACCTGTCTTGCACTACCACCCTTGATCTCACTGATGGTACCATCACCTTCAGTGACAACCTC GGAAATGTGACTGAACCAACTGGCACTTACAGTGTTCCTGCAAAAATGGGATCCAAACTGGAAGACATCTTGATGGACG ATACCCTCTCCCCCGTAGGAGTAACTGACCCACTGCTTTCCTCTGTGTCTCCTGGAGCATCGAAAACGAGTAGCAGGCG GAGCAGCGTGAGCATGGAGGACACTGATCATGCTTGTTAGCAAATACTTGGCACGCCTTTCATAAACTGCTTTGGTTCT TGATCAGTAGATTAAATATTTTGCCTTTTGTAGAATTTTTTTGATTTTTTTTTTCTTGTGCTTCATCGGTAGCCCAGTG TGTGCGTGTGTGTATATATTATATATATAGGATTTTTTTTAGAATTTTTGTGAAGAAACTTGTAAATTCTATTTTAAAA CTACCAATGCCTCCAATTATATTGTACAGCATATGTACAGTATCTGTGAACTGGATTCGACAAGAACTTTGAACTGGTC AAATCTACTCAAAGCAATAGAATTACAAATGAAGAGTCTGCTTCTATTTGGGGGGAAGGGGGAATCATAGAATTGTAAA TGCAACCTATTTACGTGGAGACAAAATGTAAAGTTACAGAATGTAAAGATACCAAAAAAGAAGTCCAATTTGTAATTGT ATTGATTTAATAGTGCTGCCTTAAAGATACAGTGTCTCTCAAACTTTGATCCTTATAGACAAGTGTTTAGGGAAGAAAA AAAGCAAACCACTCCGTTCCATTCAGAATACCAGTAATGACAAAAGTGTTAAGAAATCCTCTTTGTGTTGATGGTGATA TAAAAAGCTCTTGCTGAAAATGAAATAGAAATTGCAGGGAGATGCGAGTCCCTTCCTCAGAGTGCTCTTTGATTTTACT CTGAGCTGATTTGGGTTTTCCTTTTGATCATGGTACAACTTTCTTTTAGGCTTTAGTTTTGTTTTGTAACAGACGTTGA TGGCTTGCCACCAATAAACCGAGAAAGGAGCACTATAGGTTGGTATGCACTCTTTGGACGATAATAATCGATAGGTTTT AACAGCTGGGCACATGACGTTGTACATATCTAATTGGCTTTATTTTTTTTTTAATTGCATTGTACAGTTTATTCTGATT TGCATGGGTTCCTCAGTTACCTTCAGCCTTTCGTTTTAAATATATTTGTATTTCCTTTGTAAGAATTTGCCTCTTAATA TTGCAGCATTTCTTTTTGACATTTTAAAAACTCATTGGAAGTTTTCTGCGTTCTTTGTAAACACTTGAAAGGAAGCTTT TATGCTGGGTTCTGTGTTTTAAGAGAGATTCTGAGAATATTTTGTATATTACAGTCTCACTTTGAAAATGTTTTTAAAC ACGTTTAAGGTAGAGTTCAAATGTAGATTAGGTAATAAAACGACTTGTAGAGAAACTGAACTTACATATTTATTTTTAG TGATACAGAAGAAATAGTGATATGCTTGGAAACATAACTATGTAGTAGATATACCCGTCATAGTAATTTGTGTTTTATT TCAGCACTGGCGCTGACAT
Citation	Canto-Soler MV, Adler R. Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window. Dev Biol. 2006 Jun 1;294(1):119-32. Epub 2006 Mar 27.
Copyright	Reprinted from Developmental Biology, 294, Issue 1, M. Valeria Canto-Soler and Ruben Adler, Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window, 119-132, 2006, with permission from Elsevier. Copyright © 2006 Elsevier B.V. All rights
Comments	The authors said: Probes were generated from cDNAs generously provided by the following investigators: cMitf (Makoto Mochii, National Institute for Basic Biology, Okazaki, Japan). As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205029).

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Retina

Entry 3

GEISHA Id	MITF.Halilagic.2007	Data Source	Publication
Complete cDNA Template Probe	show GGATTCTGCTCTGCGGTTCTGCAAACCCTGAGAGCAATGGAGCCCCTGGTAGAAGCTGAGCCGTCTCTCTCTGCTCTTC CCACAGCAATTCCGAGCATCCTGGCGCTTCCAAGCCTCCCTTAAGCTCCTCCAGCATGACCTCACGAATCCTGCTACGG CAGCAGCTCATGCGTGAGCAGATGCAGGAGCAGGAGCGTCGGGAGCAGCAGCAGAAGCAGCAAGCAGCCCAGTTCATGC AACAGAGAGTTCCCGTCAGCCAGACACCTGCCATCAACGTCAGCGTGCCCGCCAGCCTGCCCCCTGCCACGCAGGTACC CATGGAGGTCCTCAAGGTGCAGACTCACCTTGAGAATCCAACCAAATACCATATTCAGCAAGCTCAGCGGCAGCAGGTA AAGCAGTACCTCTCTACCACTCTAGCAAATAAACACGCCAACCAAGCCCTGAGCTTGCCATGTCCAAACCAGCCCGGTG ATCATGTCATGCCGCCTGGAACTGGAAGCAGTGCGCCCAACAGTCCGATGGCTATGCTCACCCTCAACTCCAACTGTGA AAAAGAGGGATTTTATAAATTTGAAGAGCAAAGCAGGGTCGAGAGTGAGTGCCCGGCTCTGAATACCCACTCACGAGCA TCATGCATGCAGATGGATGATGTGATTGATGACATAATTAGTCTGGAATCAAGTTACAATGAAGAAATCCTTGGCTTGA TGGACCCAGCCTTGCAAATGGCAAATACGTTACCAGTGTCTGGGAATTTGATTGACCTTTATGGCAACCAAAGCATGCC TCCTCCAGGACTTAACATCAGCAACTCCTGTCCAGCTAATCTTCCTAATATAAAAAGGGAGCTCACAGAGTCAGAAGCG AGAGCACTGGCTAAGGAGAGGCAAAAGAAAGACAATCACAACTTGATTGAACGAAGAAGAAGATTTAATATTAATGACC GTATAAAAGAACTGGGCACCTTGATACCCAAATCAAACGACCCGGATATGCGCTGGAATAAGGGAACTATTCTAAAAGC ATCAGTGGACTACATCCGTAAGCTGCAAAGAGAGCAGCAACGCACGAAGGAACTTGAGAACAGACAGAAGAAATTGGAA CACGCCAACAGGCACCTGCTGCTCAGAATACAGGAACTTGAGATGCAAGCTCGGGCACATGGACTGTCCCTTGTTCCAT CCACAGGCATTTGCTCCCCTGATATGGTCAACAGGGTCATCAAACAAGAACCTGTGCTGGACAACTGCAACCAAGACCT CATGCCGCACCACACAGACCTGTCTTGCACTACCACCCTTGATCTCACTGATGGTACCATCACCTTCAGTGACAACCTC GGAAATGTGACTGAACCAACTGGCACTTACAGTGTTCCTGCAAAAATGGGATCCAAACTGGAAGACATCTTGATGGACG ATACCCTCTCCCCCGTAGGAGTAACTGACCCACTGCTTTCCTCTGTGTCTCCTGGAGCATCGAAAACGAGTAGCAGGCG GAGCAGCGTGAGCATGGAGGACACTGATCATGCTTGTTAGCAAATACTTGGCACGCCTTTCATAAACTGCTTTGGTTCT TGATCAGTAGATTAAATATTTTGCCTTTTGTAGAATTTTTTTGATTTTTTTTTTCTTGTGCTTCATCGGTAGCCCAGTG TGTGCGTGTGTGTATATATTATATATATAGGATTTTTTTTAGAATTTTTGTGAAGAAACTTGTAAATTCTATTTTAAAA CTACCAATGCCTCCAATTATATTGTACAGCATATGTACAGTATCTGTGAACTGGATTCGACAAGAACTTTGAACTGGTC AAATCTACTCAAAGCAATAGAATTACAAATGAAGAGTCTGCTTCTATTTGGGGGGAAGGGGGAATCATAGAATTGTAAA TGCAACCTATTTACGTGGAGACAAAATGTAAAGTTACAGAATGTAAAGATACCAAAAAAGAAGTCCAATTTGTAATTGT ATTGATTTAATAGTGCTGCCTTAAAGATACAGTGTCTCTCAAACTTTGATCCTTATAGACAAGTGTTTAGGGAAGAAAA AAAGCAAACCACTCCGTTCCATTCAGAATACCAGTAATGACAAAAGTGTTAAGAAATCCTCTTTGTGTTGATGGTGATA TAAAAAGCTCTTGCTGAAAATGAAATAGAAATTGCAGGGAGATGCGAGTCCCTTCCTCAGAGTGCTCTTTGATTTTACT CTGAGCTGATTTGGGTTTTCCTTTTGATCATGGTACAACTTTCTTTTAGGCTTTAGTTTTGTTTTGTAACAGACGTTGA TGGCTTGCCACCAATAAACCGAGAAAGGAGCACTATAGGTTGGTATGCACTCTTTGGACGATAATAATCGATAGGTTTT AACAGCTGGGCACATGACGTTGTACATATCTAATTGGCTTTATTTTTTTTTTAATTGCATTGTACAGTTTATTCTGATT TGCATGGGTTCCTCAGTTACCTTCAGCCTTTCGTTTTAAATATATTTGTATTTCCTTTGTAAGAATTTGCCTCTTAATA TTGCAGCATTTCTTTTTGACATTTTAAAAACTCATTGGAAGTTTTCTGCGTTCTTTGTAAACACTTGAAAGGAAGCTTT TATGCTGGGTTCTGTGTTTTAAGAGAGATTCTGAGAATATTTTGTATATTACAGTCTCACTTTGAAAATGTTTTTAAAC ACGTTTAAGGTAGAGTTCAAATGTAGATTAGGTAATAAAACGACTTGTAGAGAAACTGAACTTACATATTTATTTTTAG TGATACAGAAGAAATAGTGATATGCTTGGAAACATAACTATGTAGTAGATATACCCGTCATAGTAATTTGTGTTTTATT TCAGCACTGGCGCTGACAT
Citation	Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M. Retinoids control anterior and dorsal properties in the developing forebrain. Dev Bio 2007 Mar 1;303(1):244-58
Copyright	Reprinted with permission from Elsevier. Copyright © 2007 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_205029.1). Images are quail, but sequence and map shown are chick.