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NKX6-1 NK6 homeobox 1Gene | Official Symbol | NKX6-1 | Official Full Name | NK6 homeobox 1 | CGNC ID | 49457 | also known as | NKX-6.1, homeobox protein Nkx-6.1|LOW QUALITY PROTEIN: homeobox protein Nkx-6.1, NKX6.2 | gene type | protein-coding |
| Genomic Map | | Sequence Information | | Gene Expression | | Orthology | | Entrez Gene | Ensembl Gene | Genetic Phenotypes | MOD | Fruit Fly | | | | | Human | | | | | Mouse | | | | | Xenopus | | | | | Zebrafish | | | | |
| Gene Ontology | Molecular Function | | Biological Process | | Cellular Component | |
| Links to other databases | |
Entry 1GEISHA Id | NKX6-1.Gimeno.2007 | Data Source | Publication | Complete cDNA Template Probe | show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC ACACGCGGCCCACGTTCTCCGGGCAGCAGATTTTCGCTCTGGAGAAGACTTTCGAGCAGACCAAGTACCTGGCGGGCCC CGAGCGGGCGCGGCTCGCCTACTCGCTGGGCATGACCGAGAGCCAGGTGAAGGTGTGGTTCCAGAACCGGCGGACCAAG TGGCGGAAGAAACACGCGGCCGAGATGGCGACGGCCAAGAAGAAGCAGGACTCGGAGACGGAGCGGCTGAAGGGCGCCT CGGACAACGAGGACGACGACGACGACTACAACAAACCCCTCGACCCCAACTCCGACGACGAGAAGATCGCGCAGCTGCT CAAGAAACACAAACCGGGCGCCGGGGGGCTGCTGCCGCACCCCGCCGAGGGCGAGGCCTCCGCGTAGCCCGCGCACATG TACAGATCTATTTTTCTACGCTCCGAGCGGCCGGAGCCGGACTGCGGGCTCGCGTCGTCGTAGGCTCGCCGGATGCGGC CGAGCCGGGCCGGACCGCGGCGTCGTTATGGTAGGGTCGCCGGCGGCGGGGCCACCTGTTGAAGGCTCTTTGTAAATAC CCCGCGGGTCCCGGCTGTGAATAGCGCCCGTGTACGATACCTTCGTTGTTTTTTGTACGGCCGCCGGGCCCCGCGGACC GGGGGGGGACCGCCCGCGTGGCGGTGGGCTGCGGTGCCCGAGGCCGCGCCCGTAGGGAAGGAGGAAGGAAGGCAGAAAG CCCCGCAGGGCCAAACTCGCGCCGGTGGGAACCGGCGCAGCCACTTTCGGGCGGAATATAAAAACCCATTTAGTTGCTG TCATTGAATTTAAGGTGTGTTTTCCTTTTGTATCATACGGAATACTATAGAATGTAAATTGTTTTCTTCTTTCTTTTTT TTTTTTTAAAACGATGATCTATCGTGACATAGCGTCTTAACCTTTATTAATTTATATTAAAACCAATTCGGTTTGTAAA GAGAAGGAAAACCCTTTGCAACCCCGTTCGATGTAATGCACTTTCTGTTCGCAAACAAAACAACGATAAACCAATTAAA CCCTAAAAAAAAA | Citation | Gimeno L, Martinez S. Expression of chick Fgf19 and mouse Fgf15 orthologs is regulated in the developing brain by Fgf8 and Shh. Dev Dyn. 2007 Aug;236(8):2285-97. | Copyright | Copyright © 2007 Wiley-Liss, Inc. | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AF102991). |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 19-20 |
| stage 20 | | Hindbrain Midbrain
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Entry 2GEISHA Id | Nkx6.1.Politis.2007 | Data Source | Publication | Complete cDNA Template Probe | show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC ACACGCGGCCCACGTTCTCCGGGCAGCAGATTTTCGCTCTGGAGAAGACTTTCGAGCAGACCAAGTACCTGGCGGGCCC CGAGCGGGCGCGGCTCGCCTACTCGCTGGGCATGACCGAGAGCCAGGTGAAGGTGTGGTTCCAGAACCGGCGGACCAAG TGGCGGAAGAAACACGCGGCCGAGATGGCGACGGCCAAGAAGAAGCAGGACTCGGAGACGGAGCGGCTGAAGGGCGCCT CGGACAACGAGGACGACGACGACGACTACAACAAACCCCTCGACCCCAACTCCGACGACGAGAAGATCGCGCAGCTGCT CAAGAAACACAAACCGGGCGCCGGGGGGCTGCTGCCGCACCCCGCCGAGGGCGAGGCCTCCGCGTAGCCCGCGCACATG TACAGATCTATTTTTCTACGCTCCGAGCGGCCGGAGCCGGACTGCGGGCTCGCGTCGTCGTAGGCTCGCCGGATGCGGC CGAGCCGGGCCGGACCGCGGCGTCGTTATGGTAGGGTCGCCGGCGGCGGGGCCACCTGTTGAAGGCTCTTTGTAAATAC CCCGCGGGTCCCGGCTGTGAATAGCGCCCGTGTACGATACCTTCGTTGTTTTTTGTACGGCCGCCGGGCCCCGCGGACC GGGGGGGGACCGCCCGCGTGGCGGTGGGCTGCGGTGCCCGAGGCCGCGCCCGTAGGGAAGGAGGAAGGAAGGCAGAAAG CCCCGCAGGGCCAAACTCGCGCCGGTGGGAACCGGCGCAGCCACTTTCGGGCGGAATATAAAAACCCATTTAGTTGCTG TCATTGAATTTAAGGTGTGTTTTCCTTTTGTATCATACGGAATACTATAGAATGTAAATTGTTTTCTTCTTTCTTTTTT TTTTTTTAAAACGATGATCTATCGTGACATAGCGTCTTAACCTTTATTAATTTATATTAAAACCAATTCGGTTTGTAAA GAGAAGGAAAACCCTTTGCAACCCCGTTCGATGTAATGCACTTTCTGTTCGCAAACAAAACAACGATAAACCAATTAAA CCCTAAAAAAAAA | Citation | Politis PK, Rohrer H, Matsas R (2007). Expression pattern of BM88 in the developing nervous system of the chick and mouse embryo. Gene Expr Patterns. 2007 Jan;7(1-2):165-77. Epub 2006 Jul 4 | Copyright | Reprinted with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights reserved. | Comments | According to authors , "The following probes were used: ... cNkx6.1 (kindly provided by James Briscoe) .... As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # AF102991) |
Entry 3GEISHA Id | NKX6-1.Pedersen.2005 | Data Source | Publication | Complete cDNA Template Probe | show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC ACACGCGGCCCACGTTCTCCGGGCAGCAGATTTTCGCTCTGGAGAAGACTTTCGAGCAGACCAAGTACCTGGCGGGCCC CGAGCGGGCGCGGCTCGCCTACTCGCTGGGCATGACCGAGAGCCAGGTGAAGGTGTGGTTCCAGAACCGGCGGACCAAG TGGCGGAAGAAACACGCGGCCGAGATGGCGACGGCCAAGAAGAAGCAGGACTCGGAGACGGAGCGGCTGAAGGGCGCCT CGGACAACGAGGACGACGACGACGACTACAACAAACCCCTCGACCCCAACTCCGACGACGAGAAGATCGCGCAGCTGCT CAAGAAACACAAACCGGGCGCCGGGGGGCTGCTGCCGCACCCCGCCGAGGGCGAGGCCTCCGCGTAGCCCGCGCACATG TACAGATCTATTTTTCTACGCTCCGAGCGGCCGGAGCCGGACTGCGGGCTCGCGTCGTCGTAGGCTCGCCGGATGCGGC CGAGCCGGGCCGGACCGCGGCGTCGTTATGGTAGGGTCGCCGGCGGCGGGGCCACCTGTTGAAGGCTCTTTGTAAATAC CCCGCGGGTCCCGGCTGTGAATAGCGCCCGTGTACGATACCTTCGTTGTTTTTTGTACGGCCGCCGGGCCCCGCGGACC GGGGGGGGACCGCCCGCGTGGCGGTGGGCTGCGGTGCCCGAGGCCGCGCCCGTAGGGAAGGAGGAAGGAAGGCAGAAAG CCCCGCAGGGCCAAACTCGCGCCGGTGGGAACCGGCGCAGCCACTTTCGGGCGGAATATAAAAACCCATTTAGTTGCTG TCATTGAATTTAAGGTGTGTTTTCCTTTTGTATCATACGGAATACTATAGAATGTAAATTGTTTTCTTCTTTCTTTTTT TTTTTTTAAAACGATGATCTATCGTGACATAGCGTCTTAACCTTTATTAATTTATATTAAAACCAATTCGGTTTGTAAA GAGAAGGAAAACCCTTTGCAACCCCGTTCGATGTAATGCACTTTCTGTTCGCAAACAAAACAACGATAAACCAATTAAA CCCTAAAAAAAAA | Citation | Pedersen JK, Nelson SB, Jorgensen MC, Henseleit KD, Fujitani Y, Wright CV, Sander M, Serup P; Beta Cell Biology Consortium. Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol. 2005 Dec 15;288(2):487-501. | Copyright | Copyright © 2005 Elsevier Inc. All rights reserved. | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AF102991). |
Entry 4GEISHA Id | NKX6.1.Lorente-Cánovas.2012 | Data Source | Publication | Complete cDNA Template Probe | show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC ACACGCGGCCCACGTTCTCCGGGCAGCAGATTTTCGCTCTGGAGAAGACTTTCGAGCAGACCAAGTACCTGGCGGGCCC CGAGCGGGCGCGGCTCGCCTACTCGCTGGGCATGACCGAGAGCCAGGTGAAGGTGTGGTTCCAGAACCGGCGGACCAAG TGGCGGAAGAAACACGCGGCCGAGATGGCGACGGCCAAGAAGAAGCAGGACTCGGAGACGGAGCGGCTGAAGGGCGCCT CGGACAACGAGGACGACGACGACGACTACAACAAACCCCTCGACCCCAACTCCGACGACGAGAAGATCGCGCAGCTGCT CAAGAAACACAAACCGGGCGCCGGGGGGCTGCTGCCGCACCCCGCCGAGGGCGAGGCCTCCGCGTAGCCCGCGCACATG TACAGATCTATTTTTCTACGCTCCGAGCGGCCGGAGCCGGACTGCGGGCTCGCGTCGTCGTAGGCTCGCCGGATGCGGC CGAGCCGGGCCGGACCGCGGCGTCGTTATGGTAGGGTCGCCGGCGGCGGGGCCACCTGTTGAAGGCTCTTTGTAAATAC CCCGCGGGTCCCGGCTGTGAATAGCGCCCGTGTACGATACCTTCGTTGTTTTTTGTACGGCCGCCGGGCCCCGCGGACC GGGGGGGGACCGCCCGCGTGGCGGTGGGCTGCGGTGCCCGAGGCCGCGCCCGTAGGGAAGGAGGAAGGAAGGCAGAAAG CCCCGCAGGGCCAAACTCGCGCCGGTGGGAACCGGCGCAGCCACTTTCGGGCGGAATATAAAAACCCATTTAGTTGCTG TCATTGAATTTAAGGTGTGTTTTCCTTTTGTATCATACGGAATACTATAGAATGTAAATTGTTTTCTTCTTTCTTTTTT TTTTTTTAAAACGATGATCTATCGTGACATAGCGTCTTAACCTTTATTAATTTATATTAAAACCAATTCGGTTTGTAAA GAGAAGGAAAACCCTTTGCAACCCCGTTCGATGTAATGCACTTTCTGTTCGCAAACAAAACAACGATAAACCAATTAAA CCCTAAAAAAAAA | Citation | Lorente-Cánovas B, Marín F, Corral-San-Miguel R, Hidalgo-Sánchez M, Ferrán JL, Puelles L, Aroca P. Multiple origins, migratory paths and molecular profiles of cells populating the avian interpeduncular nucleus. Dev Biol. 2012 Jan 1;361(1):12-26. | Copyright | Copyright © 2011 Elsevier Inc. | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # AF102991.1). |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 25-30 | | stage 27 | | stage 27 | | Rhombomeres
| 31-39 | | stage 31 | | stage 34 | | stage 35 | | stage 35 | | stage 39 | | stage 39 | | Isthmus/MHB Rhombomeres
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Entry 5GEISHA Id | NKX6.1.Chambers.2007 | Data Source | Publication | Complete cDNA Template Probe | show ATGGCGGCGGGAGCGCGCTGTGGCCGGGCGCGGCGCTGGCAGCCCCGTCAGGGGGCGCGGAGCCGGCCGCGTCCCCGCC GCCGCGGTGTCCAGGTGCGCCCGCCGCCGGGCCGGCCCTCCCTTCTGTTGCTGGGCGGAGCGGGGCCGGCGCTGCCCGC CCCCGCGGCACCTGCGCTGCCCGTGGAGCCGCGCTCCCGGCCTGCAGGTCGGGCTGACGCGCGGGCGTCGCTCGTCTCA CCTCACGGGACAGACAGAGCTTCACTCGGGGTGCGCGCTGTAAGTGGCGGGCAGCCGGCAGGAAGCACGGAAGGCAAAA GCTACAGCCACGCTCCGGAGGGCTGCCCCGTGAGGCGCCGGGCTCCTGGGACCGGGCGCTGCCCCCGGCGCGGGGACGA GGGCCGTGGCTGCCCCCCAGAGCCGCGCGGGGATCGGTGCCCGCGGAGCGCTGCGCCCTTCCCGGCTGCACAGCAGCCC CTGGCGGCACCGGGCGCGCTCGGCGTCGGGGACGCGCGGGGAGCGGAGGGCTCCGTGCTGCGTTCCGCGCCGCAGCGAC GGGAGCGAGACGTCTTGAAAAAGCGTGGCACCTTGACGACGAGTTGGAATCAGCACGCAGCAAAGCGCTGGCACTTCCC GGCTCGGTCCTTTTCCCAGCACAGGGAGGACCACGAGCGATTCGGTGCCCGCACGGTGCCCGAATGCCGCCCGGCACTC TCAGGGGGTGGCTGGCGAACAGCGCTCGGTGACGGCGGAGCGCTGTATGCGCCGAACAAAGCGGCCGCTCCGCTGAGGT CCCCCCCGGGCCCCGCGCTCTTCGCTACCGGCTGCCGCGGCGGTTCCCGAAGAGCCGCGCTCGTCCCCGTGCTGAGTGC CAAACGCAGCAGCAAAGCCCCGCGGGTCGCTCCCAGCCGCGCTGCTCCCGCCCGCCTCTCCCTTCGTCTCCCGGCCGCG CGGCCCCGCAGACCCGAACGGGTCGGGCCGTGCCGAGGTTTTTCCCTCCGGGCCGGGGCTGCCCGGGGACGGCGGCAGC GGGAAGGGCCAGGCCCGGGGCAGCGCAGCGGCTCCGCTCCGAAGCCGCCGCCCGCCGCCGCCCCGCCGCCTCCCGCCGG CCCCGCCGCGCTGCTGGCCGCGCTGCCGCGCTTCGGCAGCCTCAGCCCGCCGCCGCCGCCGCCGCCGCCGCCCGCGCTC TACTTCGGCGCCGCCGCCGCCGTGGCCGCCGCCGGGCGCTACACGAAGCCGCTGGCCGAGCTGCCCGGGCGGGCGCCCA TCTTCTGGCCCGGCGTGGTGCAGGGCCCGCCATGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCT GCTGGACAAGGACGGCAAGAGGAAGCACACGCGGCCCACGTTCTCCGGGCAGCAGATTTTCGCTCTGGAGAAGACTTTC GAGCAGACCAAGTACCTGGCGGGCCCCGAGCGGGCGCGGCTCGCCTACTCGCTGGGCATGACCGAGAGCCAGGTGAAGG TGTGGTTCCAGAACCGGCGGACCAAGTGGCGGAAGAAACACGCGGCCGAGATGGCGACGGCCAAGAAGAAGCAGGACTC GGAGACGGAGCGGCTGAAGGGCGCCTCGGACAACGAGGACGACGACGACGACTACAACAAACCCCTCGACCCCAACTCG GACGACGAGAAG | Citation | Chambers D, Wilson L, Maden M, Lumsden A. RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1. Development. 2007 Apr;134(7):1369-83. | Copyright | © 2007 | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # XM_003641196.1). |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 13-16 | | stage 16 | | stage 16 | | stage 16 | | Hindbrain Neural Plate/Tube
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Entry 6GEISHA Id | NKX6.1.GarciaCampmany.2007 | Data Source | Publication | Complete cDNA Template Probe | show ATGGCGGCGGGAGCGCGCTGTGGCCGGGCGCGGCGCTGGCAGCCCCGTCAGGGGGCGCGGAGCCGGCCGCGTCCCCGCC GCCGCGGTGTCCAGGTGCGCCCGCCGCCGGGCCGGCCCTCCCTTCTGTTGCTGGGCGGAGCGGGGCCGGCGCTGCCCGC CCCCGCGGCACCTGCGCTGCCCGTGGAGCCGCGCTCCCGGCCTGCAGGTCGGGCTGACGCGCGGGCGTCGCTCGTCTCA CCTCACGGGACAGACAGAGCTTCACTCGGGGTGCGCGCTGTAAGTGGCGGGCAGCCGGCAGGAAGCACGGAAGGCAAAA GCTACAGCCACGCTCCGGAGGGCTGCCCCGTGAGGCGCCGGGCTCCTGGGACCGGGCGCTGCCCCCGGCGCGGGGACGA GGGCCGTGGCTGCCCCCCAGAGCCGCGCGGGGATCGGTGCCCGCGGAGCGCTGCGCCCTTCCCGGCTGCACAGCAGCCC CTGGCGGCACCGGGCGCGCTCGGCGTCGGGGACGCGCGGGGAGCGGAGGGCTCCGTGCTGCGTTCCGCGCCGCAGCGAC GGGAGCGAGACGTCTTGAAAAAGCGTGGCACCTTGACGACGAGTTGGAATCAGCACGCAGCAAAGCGCTGGCACTTCCC GGCTCGGTCCTTTTCCCAGCACAGGGAGGACCACGAGCGATTCGGTGCCCGCACGGTGCCCGAATGCCGCCCGGCACTC TCAGGGGGTGGCTGGCGAACAGCGCTCGGTGACGGCGGAGCGCTGTATGCGCCGAACAAAGCGGCCGCTCCGCTGAGGT CCCCCCCGGGCCCCGCGCTCTTCGCTACCGGCTGCCGCGGCGGTTCCCGAAGAGCCGCGCTCGTCCCCGTGCTGAGTGC CAAACGCAGCAGCAAAGCCCCGCGGGTCGCTCCCAGCCGCGCTGCTCCCGCCCGCCTCTCCCTTCGTCTCCCGGCCGCG CGGCCCCGCAGACCCGAACGGGTCGGGCCGTGCCGAGGTTTTTCCCTCCGGGCCGGGGCTGCCCGGGGACGGCGGCAGC GGGAAGGGCCAGGCCCGGGGCAGCGCAGCGGCTCCGCTCCGAAGCCCGCCGGCCCCGCCGCGCTGCTGGCCGCGCTGCC GCGCTTCGGCAGCCTCAGCCCGCCGCCGCCGCCGCCGCCGCCGCCCGCGCTCTACTTCGGCGCCGCCGCCGCCGTGGCC GCCGCCGGGCGCTACACGAAGCCGCTGGCCGAGCTGCCCGGGCGGGCGCCCATCTTCTGGCCCGGCGTGGTGCAGGGCC CGCCATGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGCA CACGCGGCCCACGTTCTCCGGGCAGCAGATTTTCGCTCTGGAGAAGACTTTCGAGCAGACCAAGTACCTGGCGGGCCCC GAGCGGGCGCGGCTCGCCTACTCGCTGGGCATGACCGAGAGCCAGGTGAAGGTGTGGTTCCAGAACCGGCGGACCAAGT GGCGGAAGAAACACGCGGCCGAGATGGCGACGGCCAAGAAGAAGCAGGACTCGGAGACGGAGCGGCTGAAGGGCGCCTC GGACAACGAGGACGACGACGACGACTACAACAAACCCCTCGACCCCAACTCGGACGACGAGAAG | Citation | García-Campmany L, Martí E. The TGFbeta intracellular effector Smad3 regulates neuronal differentiation and cell fate specification in the developing spinal cord. Development. 2007 Jan;134(1):65-75. Epub 2006 Nov 30. | Copyright | Copyright by the authors. Published by the Company of Biologists Ltd. | Comments | As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI XM_003641196.2 |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 7-12 | | stage 12 | | stage 12 | | Spinal Cord
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| Data from NCBI Unigene EST Profile Unigene ID: Gga.4083 |
MouseFrogFruit FlyZebra FinchZebrafish
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