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NKX6-1 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol NKX6-1 Official Full Name NK6 homeobox 1 CGNC ID 49457 also known as NKX-6.1, homeobox protein Nkx-6.1|LOW QUALITY PROTEIN: homeobox protein Nkx-6.1, NKX6.2 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Entrez Gene Ensembl Gene Genetic Phenotypes MOD Fruit Fly Human Mouse Xenopus Zebrafish
Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id NKX6-1.Gimeno.2007 Data Source Publication Complete cDNA Template Probe show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC
Citation Gimeno L, Martinez S. Expression of chick Fgf19 and mouse Fgf15 orthologs is regulated in the developing brain by Fgf8 and Shh. Dev Dyn. 2007 Aug;236(8):2285-97. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AF102991).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-20
stage 20
Hindbrain Midbrain
Entry 2 GEISHA Id Nkx6.1.Politis.2007 Data Source Publication Complete cDNA Template Probe show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC
Citation Politis PK, Rohrer H, Matsas R (2007). Expression pattern of BM88 in the developing nervous system of the chick and mouse embryo. Gene Expr Patterns. 2007 Jan;7(1-2):165-77. Epub 2006 Jul 4 Copyright Reprinted with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights reserved. Comments According to authors , "The following probes were used: ... cNkx6.1 (kindly provided by James Briscoe) .... As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # AF102991)
Entry 3 GEISHA Id NKX6-1.Pedersen.2005 Data Source Publication Complete cDNA Template Probe show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC
Citation Pedersen JK, Nelson SB, Jorgensen MC, Henseleit KD, Fujitani Y, Wright CV, Sander M, Serup P; Beta Cell Biology Consortium. Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol. 2005 Dec 15;288(2):487-501. Copyright Copyright © 2005 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (AF102991).
Entry 4 GEISHA Id NKX6.1.Lorente-Cánovas.2012 Data Source Publication Complete cDNA Template Probe show CCGCCCTGGAGGGACGCCCGCATCGGCTGCGCGCCGCATCAAGGCTCGATCCTGCTGGACAAGGACGGCAAGAGGAAGC
Citation Lorente-Cánovas B, Marín F, Corral-San-Miguel R, Hidalgo-Sánchez M, Ferrán JL, Puelles L, Aroca P. Multiple origins, migratory paths and molecular profiles of cells populating the avian interpeduncular nucleus. Dev Biol. 2012 Jan 1;361(1):12-26. Copyright Copyright © 2011 Elsevier Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # AF102991.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 27
stage 27
Rhombomeres 31-39 stage 31
stage 34
stage 35
stage 35
stage 39
stage 39
Isthmus/MHB Rhombomeres
Entry 5 GEISHA Id NKX6.1.Chambers.2007 Data Source Publication Complete cDNA Template Probe show ATGGCGGCGGGAGCGCGCTGTGGCCGGGCGCGGCGCTGGCAGCCCCGTCAGGGGGCGCGGAGCCGGCCGCGTCCCCGCC
Citation Chambers D, Wilson L, Maden M, Lumsden A. RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1. Development. 2007 Apr;134(7):1369-83. Copyright © 2007 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # XM_003641196.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-16 stage 16
stage 16
stage 16
Hindbrain Neural Plate/Tube
Entry 6 GEISHA Id NKX6.1.GarciaCampmany.2007 Data Source Publication Complete cDNA Template Probe show ATGGCGGCGGGAGCGCGCTGTGGCCGGGCGCGGCGCTGGCAGCCCCGTCAGGGGGCGCGGAGCCGGCCGCGTCCCCGCC
Citation García-Campmany L, Martí E. The TGFbeta intracellular effector Smad3 regulates neuronal differentiation and cell fate specification in the developing spinal cord. Development. 2007 Jan;134(1):65-75. Epub 2006 Nov 30. Copyright Copyright by the authors. Published by the Company of Biologists Ltd. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI XM_003641196.2
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Spinal Cord
Data from NCBI Unigene EST ProfileGga.4083
Mouse Frog Fruit Fly Zebra Finch Zebrafish
