GEISHA - A Chicken Embryo Gene Expression Database
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NKX2-6
NK2 homeobox 6

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolNKX2-6
Official Full NameNK2 homeobox 6
CGNC ID49622
also known asNKX2.8, homeobox protein Nkx-2.6|NK2 transcription factor related, locus 6|homeobox protein Nkx-2.8
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205137
PolypeptideNP_990468
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.610
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human137814ENSG00000180053MIM:217095MIM:611770
Mouse18092ENSMUSG00000044186All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2) MGI:97351
Xenopus100038094, 373736486950
Zebrafish30694ENSDARG00000021232ZDB-GENE-990415-179ZFIN:ZDB-GENE-990415-179
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene396037
Ensembl Gene
KEGGgga:396037

Entry 1

GEISHA IdNKX2.6.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerTGCCACCACCCCAAGCAAC
Reverse cDNA Template PrimerAATTAACCCTCACTAAAGTCCGCAGCACCAGAAGTCCcDNA Template Length
Forward cDNA Template Probeshow
AACTCCCTTTCTTGGGCTGGTTGGTGAGGTTGGACGCACCACCTGGCTGTCCATTACGACTCCGGATGCCCCCATCCCT
TTCCTGGGCCACATCTCAACTGGTGCTGAGCCCAAGCTCATGGTGTGAGCACCCCAGTATATCCCACCCCATAGCTCAC
CCCGTAGGCACTGTAGTAGGTGCTATAGGAGTAGGGGCTGACGGTGATCCCATAAGGAGCCAGGTGGGGTTGGGACCCC
TCAAAGCAAGGCTTGCCATCTCTGACCAGCACCGGAACAGCCACTCTACGTGGTGGCAGTGGGTAGGTGGCCATCTCCA
GGGATCTATCCTGCCTCTGCCTCTTGCATTTGTAGCGCCGGTTCTGGAACCAGATTTTCACCTGGGTGGAGGTGAGCTG
GAGCACGTTGGCCAGGTGTTCCCTTTCCAGTGCAGAGAGGTATTTCTGCTGCTTGAATCGCCGCTCCAACTCCAACACC
TGAGTTTGGGAGAACAAAACGCGGGGTTTGCGCCGCTGCGGTTGCTTGGGGTGGTGGCAANA
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 6
Unlabeled
Stages 5 & 6.
7-12
stage 7
stage 8
stage 9
stage 10
Anterior Intestinal Portal
Anterior/Second Heart Field
Extraembryonic Mesoderm
Heart Tube
Lateral Plate Mesoderm
 
13-18
stage 13
stage 13
stage 14
stage 14
stage 14
stage 14
stage 16
stage 18
Anterior/Second Heart Field
Foregut
Heart
Heart Tube
Outflow Tract
Pharyngeal Arches and Clefts
Pharynx
Sinus Venosus
Spinal Cord
 
19-24
stage 20
stage 20
stage 24
Anterior/Second Heart Field
Eye
Head Mesenchyme
Outflow Tract
Pharyngeal Arches and Clefts
Trunk Mesenchyme
 
25
stage 25
Anterior/Second Heart Field
Eye
Forebrain
Head Mesenchyme
Outflow Tract
Trunk Mesenchyme
 

Entry 2

GEISHA IdNKx2–8.Brand.1997Data SourcePublication
Complete cDNA Template Probeshow
CACCGATCCCCCCCCGGAGGATGCTGCCCACCCCTTTCTCCGTCGAGGATATCCTCAGCCTGGAGCAGAGCAGCGCTCC
CGGAGCCCCCCGGGGTCCGCCGCAGCCCTTCCGTGGAGGAGGAACCGCCGTCGGACAATGTCTGCTCTCCCAGCCCTTG
CAGGCAGACCAGCAGCAAACTGACCCCTGCCACCACCCCAAGCAACCGCAGCGGCGCAAACCCCGCGTTTTGTTCTCCC
AAACTCAGGTGTTGGAGTTGGAGCGGCGATTCAAGCAGCAGAAATACCTCTCTGCACTGGAAAGGGAACACCTGGCCAA
CGTGCTCCAGCTCACCTCCACCCAGGTGAAAATCTGGTTCCAGAACCGGCGCTACAAATGCAAGAGGCAGAGGCAGGAT
AGATCCCTGGAGATGGCCACCTACCCACTGCCACCACGTAGAGTGGCTGTTCCGGTGCTGGTCAGAGATGGCAAGCCTT
GCTTTGAGGGGTCCCAACCCCACCTGGCTCCTTATGGGATCACCGTCAGCCCCTACTCCTATAGCACCTACTCAGTGCC
TACGGGGGTGAGCTATGGGGTGGGATATACTGGGGTGCTCACACCATGAGCTTGGGCTCAGCACCAGTTGAGATGTGGC
CCAGGAAAGGGATGGGGGCATCCGGAGTCGTAATGGACAGCAGGTGGTGCGTCCAACCTCACCAACCAGCCCAAGGAAA
GGGACTTCTGGTGCTGCGGGATTTGGGGACCTCAGTGCAGGGGCATTTATTTATTTGGGCACAAACATGGAGTCCATCC
CATCTCACCCCATAGGGATGGTCCTGTGGGATGCATAGGGATGGGATGCTGCTCTTCTTCCTAAGGAAACAGGGTCTGT
GCACACCACTGCGCCTTTGCTTTTCCATGAACACTCTATTTAAGGCTTTGAGTTCCTCTCATCTTTTGGGATATTCATA
TTTCTTAATGACTTAAAAGCACAGGTGTTCGTTTCTGTCTTGGTTATTGTTATTATTTGCAATTAAAAAAAAATAAGGT
GGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
CitationBrand T, Andrée B, Schneider A, Buchberger A, Arnold HH. Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development. Mech Dev. 1997 Jun;64(1-2):53-9.
CopyrightCopyright © 1997 Published by Elsevier Ireland Ltd.
CommentsThe complete cDNA template sequence was obtained from the information in the publication as described in Brand et al. 1997. NKX2-8 is also known as NKX2-6 in NCBI.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 6
Foregut
 
7-12
stage 9
stage 9
stage 10
stage 10
stage 11
stage 11
stage 12
stage 12
stage 12
Foregut
Heart Tube
Myocardium
Pharyngeal Arches and Clefts
Sinus Venosus
 
13-18
stage 18
stage 18
stage 18
Heart
Pharyngeal Arches and Clefts
 
31-44
stage 44
stage 44
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.610

Mouse

EmageMGI:97351
EurexpressMGI:97351
MGI GXDMGI:97351

Frog

Xenbase486950

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-990415-179
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