Quick Search
X XI XII XIII XIV 1 2 3 4 5 6 7 8 9 10 11 12
13 14 15 16 17 18 19 20 21 22 23 24
25 26 27 28 29 30 31 32 33 34 35 36
37 38 38 40 41 42 43 44
Gene Family QuickSearch
Human Disease Gene Search
PAX6 The human orthologue of this gene is associated
Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol PAX6 Official Full Name paired box 6 CGNC ID 49564 also known as PAX-6, paired box protein Pax-6|paired box gene 6, Pax-6 ,
paired box gene 6 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Links to other databases
Entry 1 GEISHA Id Pax6.Jensen.2005 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Jensen A. Potential Roles for BMP and Pax Genes in the Development of Iris Smooth Muscle. Dev Dyn. 2005 Feb;232(2):385-92. Copyright Copyright © 2005 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_205066)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-39
stage 31
stage 36
stage 39
Eye Retina
Entry 2 GEISHA Id PAX6.Gimeno.2007 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Gimeno L, Martinez S. Expression of chick Fgf19 and mouse Fgf15 orthologs is regulated in the developing brain by Fgf8 and Shh. Dev Dyn. 2007 Aug;236(8):2285-97. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Entry 3 GEISHA Id PAX6.Ohuchi.2007 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Ohuchi H, Hayashibara Y, Matsuda H, Onoi M, Mitsumori M, Tanaka M, Aoki J, Arai H, Noji S. Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development. Dev Dyn. 2007 Apr;236(4):1134-43. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Entry 4 GEISHA Id PAX6.Garcia-Calero.2006 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation García-Calero E, Garda AL, Marín F, Puelles L. Expression of Lrrn1 marks the prospective site of the zona limitans thalami in the early embryonic chicken diencephalon. Gene Expr Patterns. 2006 Oct;6(8):879-85. Epub 2006 Feb 28. Copyright Reprinted with permission from Elsevier. Copyright © 2006 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Entry 5 GEISHA Id Pax6.Bhattacharyya.2004 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Bhattacharyya S, Bailey AP, Bronner-Fraser M, Streit A. Segregation of lens and olfactory precursors from a common territory: cell sorting and reciprocity of Dlx5 and Pax6 expression. Dev Biol. 2004 Jul 15;271(2):403-14. Copyright Reprinted from Developmental Biology, Volume 271, Issue 2, Sujata Bhattacharyya, Andrew P. Bailey, Marianne Bronner-Fraser, and Andrea Streit, Segregation of lens and olfactory precursors from a common territory: cell sorting and reciprocity of Dlx5 and Pax6 expression, Pages 403-414, Copyright 2004, with permission from Elsevier.
Copyright © 2004 Elsevier B.V. All rights reserved. Comments Authors indicate that the cDNAs for Pax6 came from Goulding et al., 1993), and they said:a 520 bp fragment spanning both the homeobox and paired box was used for Pax-6. As information provided is insufficient to verify exact sequence used to synthesize the probe, the sequence below was obtained from NCBI (Acc# NM_205066.1)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 7
stage 7
stage 8
stage 10
stage 10
Neural Plate/Tube Surface Ectoderm
Entry 6 GEISHA Id PAX6.Agarwala.2005 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Agarwala S, Aglyamova GV, Marma AK, Fallon JF, Ragsdale CW. Differential susceptibility of midbrain and spinal cord patterning to floor plate defects in the talpid2 mutant. Dev Biol. 2005 Dec 1;288(1):206-20. Epub 2005 Oct 21. Copyright Copyright © 2005 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-28 stage 26
stage 28
stage 28
Forebrain Midbrain
Entry 7 GEISHA Id Pax6.Maden.2007 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A. (2007). Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo. Int J Dev Biol. 2007;51(3):191-200. Copyright "Reprinted from Int. J. Dev. Biol., 51, Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A, Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo, 191-200, Copyright (2007), with permission from Copyright © 2007 UBC Press". All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_205066). Thus images are from Quail, but sequence shown and map are the chick homolog.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-14 stage 14
Eye
Entry 8 GEISHA Id PAX6.Vieira.2005 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Vieira C, Garda AL, Shimamura K, Martinez S. Thalamic development induced by Shh in the chick embryo. Dev Biol. 2005 Aug 15;284(2):351-63. Copyright Copyright © 2005 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-23 stage 23
Diencephalon Midbrain
Entry 9 GEISHA Id PAX6.Bell.2001 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Bell E, Ensini M, Gulisano M, Lumsden A. Dynamic domains of gene expression in the early avian forebrain. Dev Biol. 2001 Aug 1;236(1):76-88. Copyright Copyright © 2001 Academic Press All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 8
stage 9
stage 10
stage 11
stage 12
Diencephalon Forebrain Rhombomeres 13-18 stage 13
19-20 stage 20
stage 20
stage 20
Telencephalon
Entry 10 GEISHA Id PAX6.Zhang.2001 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Zhang XM, Yang XJ (2001). Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis. Dev Biol. 2001 May 15;233(2):271-90. Copyright Copyright © 2001 Academic Press. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 22
stage 22
stage 24
stage 24
Eye Lens Retina
Entry 11 GEISHA Id PAX6.Spieler.2004 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Spieler D, Bäumer N, Stebler J, Köprunner M, Reichman-Fried M, Teichmann U, Raz E, Kessel M, Wittler L. Involvement of Pax6 and Otx2 in the forebrain-specific regulation of the vertebrate homeobox gene ANF/Hesx1. Dev Biol. 2004 May 15;269(2):567-79. Copyright Copyright © 2004 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-8 stage 8
stage 8
stage 8
Neural Plate/Tube
Entry 12 GEISHA Id PAX6.Bhattacharyya.2008 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Entry 13 GEISHA Id PAX6.Bailey.2006 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Bailey AP, Bhattacharyya S, Bronner-Fraser M, Streit A. Lens specification is the ground state of all sensory placodes, from which FGF promotes olfactory identity. Dev Cell. 2006 Oct;11(4):505-17. Copyright Copyright © 2006, Elsevier Comments Insufficient information provided in publication to verify exact sequence to synthesize probe. Sequence below was obtained from NCBI (NM_205066).
Entry 14 GEISHA Id Pax6.Garcia-Lopez.2009 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation García-López R, Soula C, Martínez S. Expression analysis of Sulf1 in the chick forebrain at early and late stages of development. Dev Dyn. 2009 Sep;238(9):2418-29. Copyright Copyright © 2009 John Wiley & Sons, Inc. All Rights Reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205066.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-26 stage 26
Neural Plate/Tube
Entry 15 GEISHA Id PAX6.Agarwala.2002 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Agarwala S, Ragsdale CW. A role for midbrain arcs in nucleogenesis. Development. 2002 Dec;129(24):5779-88. Copyright Published by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Permission granted by Dr. Ragsdale. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (NM_205066).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 10
stage 12
Isthmus/MHB Midbrain
Entry 16 GEISHA Id PAX6.Sanders.2002 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Sanders TA, Lumsden A, Ragsdale CW. Arcuate plan of chick midbrain development. J Neurosci. 2002 Dec 15;22(24):10742-50. Copyright Copyright © 2002-2011 by the Society for Neuroscience Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_205066.1)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 19
stage 19
Midbrain 25-26 stage 26
stage 26
stage 26
stage 26
Midbrain
Entry 17 GEISHA Id PAX6.Ohuchi.2010 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTTTTAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGTAACGGCCCCTC
Citation Ohuchi H, Fukui H, Matsuyo A, Tomonari S, Tanaka M, Arai H, Noji S, Aoki J. Autotaxin controls caudal diencephalon-mesencephalon development in the chick. Dev Dyn. 2010 Oct;239(10):2647-58. Copyright Copyright © 19992011 John Wiley & Sons, Inc. All Rights Reserved.
Entry 18 GEISHA Id PAX6.Halilagic.2007 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M. Retinoids control anterior and dorsal properties in the developing forebrain. Dev Bio 2007 Mar 1;303(1):244-58 Copyright Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_205066). Images are quail, but sequence and map shown are chick.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19 stage 19
stage 19
stage 19
stage 19
Diencephalon Eye Telencephalon
Entry 19 GEISHA Id PAX6.Merchan.2011 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Merchán,P, Bardet, SM, Puelles, L, Ferran, JL, Comparison of Pretectal Genoarchitectonic Pattern between Quail and Chicken Embryos. Front Neuroanat. 2011; 5: 23. Prepublished online 2010 December 29. Published online 2011 April 5 Copyright Copyright © 2011 Merchán, Bardet, Puelles and Ferran.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-26 stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
Diencephalon Midbrain
Entry 20 GEISHA Id PAX6.BeleckyAdams.1997 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Belecky-Adams T, Tomarev S, Li HS, Ploder L, McInnes RR, Sundin O, Adler R. Pax-6, Prox 1, and Chx10 homeobox gene expression correlates with phenotypic fate of retinal precursor cells. Invest Ophthalmol Vis Sci. 1997 Jun;38(7):1293-303. Copyright Copyright Association for Research in Vision and Ophthalmology Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205066.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 26
stage 26
Retina 31-44 stage 34
stage 41
stage 41
stage 44
stage 44
Retina
Entry 21 GEISHA Id PAX6.Golden.1999 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Golden JA, Bracilovic A, McFadden KA, Beesley JS, Rubenstein JL, Grinspan JB. Ectopic bone morphogenetic proteins 5 and 4 in the chicken forebrain lead to cyclopia and holoprosencephaly. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2439-44. Copyright Copyright © 2012 National Academy of Sciences. All rights reserved.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-23 stage 23
Eye Forebrain
Entry 22 GEISHA Id PAX6.Davey.2006 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Davey MG, Paton IR, Yin Y, Schmidt M, Bangs FK, Morrice DR, Smith TG, Buxton P, Stamataki D, Tanaka M, Münsterberg AE, Briscoe J, Tickle C, Burt DW. The chicken talpid3 gene encodesa novel protein essentialfor Hedgehog signaling. Genes Dev. 2006 May 15; 20(10): 13651377. Copyright Copyright © 2006, Cold Spring Harbor Laboratory Press Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_205066.1 ).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-20 stage 20
stage 20
Spinal Cord
Entry 23 GEISHA Id PAX6.Schubert.2005 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Schubert FR, Lumsden A. Transcriptional control of early tract formation in the embryonic chick midbrain. Development. 2005 Apr;132(8):1785-93. Epub 2005 Mar 16. Copyright copyright 2005 by the authors. Published by the Company of Biologists Ltd. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_205066.1 ).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 20
stage 21
stage 21
Mesencephalon 25 stage 25
stage 25
Mesencephalon
Entry 24 GEISHA Id PAX6.Frowein.2002 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Frowein J, Campbell K, Götz M. Expression of Ngn1, Ngn2, Cash1, Gsh2 and Sfrp1 in the developing chick telencephalon. Mech Dev. 2002 Jan;110(1-2):249-52. Copyright Copyright © 2002 Elsevier Science Ireland Ltd. All rights reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (NM_205066.1)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31 stage 31
stage 31
Telencephalon
Entry 25 GEISHA Id PAX6.Bertrand.2000 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Bertrand N, Médevielle F, Pituello F FGF signalling controls the timing of Pax6 activation in the neural tube. Development. 2000 Nov;127(22):4837-43. Copyright copyright held by the authors. Published by the Company of Biologists, Ltd. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_205066.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
stage 10
Neural Plate/Tube
Entry 26 GEISHA Id PAX6.Ferran.2007 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Ferran JL, Sánchez-Arrones L, Sandoval JE, Puelles L. A model of early molecular regionalization in the chicken embryonic pretectum. J Comp Neurol. 2007 Dec 1;505(4):379-403. Copyright Copyright © 19992012 John Wiley & Sons, Inc. All Rights Reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. #NM_205066.1).
Entry 27 GEISHA Id PAX6.Mercier.2012 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Mercier S, David V, Ratié L, Gicquel I, Odent S, Dupé V.. NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos. Dis Model Mech. 2013 March; 6(2): 537543. Published online 2012 December 20. Copyright Copyright © 2013. Published by The Company of Biologists Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-ncsa/ 3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_205066.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Head Mesenchyme
Entry 28 GEISHA Id PAX6.Christophorou.2009 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Christophorou NA, Bailey AP, Hanson S, Streit A. Activation of Six1 target genes is required for sensory placode formation. Dev Biol. 2009 Dec 15;336(2):327-36. doi: 10.1016/j.ydbio.2009.09.025. Epub 2009 Sep 23. Copyright Copyright © 2013 Elsevier B.V. All rights reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_205066.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 4 stage 4
stage 4
Neural Plate/Tube
Entry 29 GEISHA Id PAX6.Tsukiji.2009 Data Source Publication Complete cDNA Template Probe show CCCGCTGCCCCGGCCCACCATGCAGAACAGTCACAGCGGCGTGAACCAGCTCGGCGGGGTGTTCGTCAACGGGAGGCCG
Citation Tsukiji N, Nishihara D, Yajima I, Takeda K, Shibahara S, Yamamoto H. Mitf functions as an in ovo regulator for cell differentiation and proliferation during development of the chick RPE. Dev Biol. 2009 Feb 15;326(2):335-46. doi: 10.1016/j.ydbio.2008.11.029. Epub 2008 Dec 7. Copyright Copyright © 2013 Elsevier B.V. All rights reserved. Comments The probe was amplified by PCR using the following primers:
5'-CCCGCTGCCCCGGCCCACCATGC-3' and 5'-GGATCGGCTGGTAAACGCTTGT-3' and was extracted from NCBI Acc# NM_205066.1.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-22 stage 22
stage 22
Eye
Entry 30 GEISHA Id PAX6.Hirashima.2008 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Hirashima M, Kobayashi T, Uchikawa M, Kondoh H, Araki M. Anteroventrally localized activity in the optic vesicle plays a crucial role in the optic development. Dev Biol. 2008 May 15;317(2):620-31. doi: 10.1016/j.ydbio.2008.03.010. Epub 2008 Mar 20. Copyright Copyright © 2008 Elsevier Inc. All rights reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_205066.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-11 stage 11
stage 11
Eye
Entry 31 GEISHA Id PAX6.Marcucio.2005 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Marcucio RS, Cordero DR, Hu D, Helms JA. Molecular interactions coordinating the development of the forebrain and face. Dev Biol. 2005 Aug 1;284(1):48-61. Copyright Copyright © 2005 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_205066.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-22 stage 22
Telencephalon all
Entry 32 GEISHA Id Pax6.Joshi.2019 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Piyush Joshi, Andrew J Darr, Isaac Skromne. CDX4 regulates the progression of neural maturation in the spinal cord. Dev Biol. 2019 May 15;449(2):132-142. Epub 2019 Feb 28. DOI: 10.1016/j.ydbio.2019.02.014. Copyright Copyright © 2019 Elsevier Inc. Comments Authors indicated the probe was made from Pax6 gene construct provided by Dr. Martyn Gouldin. As insufficient information is provided in publication to verify exact sequence used to synthesize probe, above sequence was obtained from NCBI (NM_205066.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-11 stage 11
Neural Plate/Tube all
Entry 33 GEISHA Id PAX6.Olivera-Martinez.2014 Data Source Publication Complete cDNA Template Probe show TTCCGGCGTAGGAATCGCCGAGCGGAGCCGCCAGGTGCCTCCTCGGGCCGCCGCGCCGCCGGACAGGACCTCGGCATCG
Citation Isabel Olivera-Martinez, Nick Schurch, Roman A Li, Junfang Song, Pamela A Halley, Raman M Das, Dave W Burt, Geoffrey J Barton, Kate G Storey. Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo. Development 2014 Aug;141(16):3266-76. Epub 2014 Jul 25. DOI: 10.1242/dev.112623. Copyright Copyright © 2014. Published by The Company of Biologists Ltd. Comments Authors indicated the probe was made from gene construct provided by J. Briscoe. As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_205066.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
Neural Plate/Tube all
Data from NCBI Unigene EST ProfileGga.556
Mouse Frog Fruit Fly Zebra Finch Zebrafish
