GEISHA - A Chicken Embryo Gene Expression Database
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PCDH8
protocadherin 8

Gene
Official SymbolPCDH8
Official Full Nameprotocadherin 8
CGNC ID53254
also known asprotocadherin-8, protocadherin-8|paraxial protocadherin 8 short isoform
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001098609
PolypeptideNP_001092079
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.30329
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human5100ENSG00000136099MIM:603580
Mouse18530ENSMUSG00000036422All phenotypic alleles (1):Targeted, knock-out(1) MGI:1306800
Xenopus448128, 3793805887885
Zebrafish100002026, 30456ENSDARG00000006467ZDB-GENE-980526-242ZFIN:ZDB-GENE-980526-242
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene428065
Ensembl Gene
KEGGgga:428065

Entry 1

GEISHA IdProcad8Data SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
ACGGTGTGTGGAGTTGAGTGCAGTCCCCGCACCGCGTCCCCTCTCTGAGTCCCGCGCAGGTGCCATGAGCCCCCTGCGG
CTGCTGGCCGCCGGCTGCCTGCTGGCCCTGTCCCACTGCAAGACGGTGCGCTACCGCACCGACGAGGAAGGCGCGCCGG
GCACGGTGATCGGCACGCTGGCCGACGAGATGCCGGTGAAGGCTCCGGGGGAGATGAGCTTCCGACTGATGCGGCAGTT
CAGCAACAGCTCGCTGGTGCGGGTGCGGGAGGAGGACGGGCAGCTGAGCATCGGCGAGGCTGGGCTGGACCGGGAGCGG
CTGTGCGGGCAGGCCCCGCAGTGCGTGCTGGCCTTCGACGTGGTGAGCTGCTGGCGGGAGCGCTACCGCCTGGTGCACG
TGGAGCTGGAGGTGCGAGACATCAACGACAACGCGCCCCACTTCCCCCGTGCCCAGATGGCGCTGGAGGTGTCGGAGAG
CGCCGCTCCTGGCACTCGCCTCCCACTCGAGGTGGCCGTGGACGAGGATGTGGGCTCCAACTCCATCCAGAGCTTCCAG
GTCTCCCTCAACAGCCACTTCGGTGTGGAAGCGCAGACGCGGGCAGACGGGGCGCGCTGCGCGGATCTGGTGCTGCTGC
AGGAGCTGGACCGCGAGCGCCAGCCTTCCTACACCCTGGAGCTGGTGGCCAAGGACGGCGGCAGCCCTGCACGCTCAGG
CACAGCCACGGTGCACGTCCGCGTCCTCGATGCCAACGACAACAGCCCCACTTTTGCCCGGAGCTCTGTGACAGTGGAG
CTGCCGGAAGACGCGCCGCCTGGCTCCCTGCTGCTTGACCTGGATGCCGAAGACCCCGACGAGGGCCCCAACGGAGAGG
TCGTCTATGCCTTTGGCAGTCAGGTGCCCCCTGAGGCACGGCGGCTCTTCCGCCTAGACCCACGCTCAGGCCGCCTGAC
GCTGGAGGCTGCCGTGGACTATGAGCGTACCCGCACCTACGAGCTGGACGTGCGGGCCCAGGATCGCGGTGCCAGCCCC
AGGACCGCGACCTGCACCGTCGTGGTGCGCCTTACCGACGTCAACGACAACGCGCCACGCATCAGCATCAGCGCCCTGC
GTGGTGCCGGCAGCGCCGCCGGCGTGGCCTACGTCAGCGAGGCGGCTGCCAGTGAGAGCTTCGTGGCCCTCGTCAGCGC
TTCCGACCGTGACTCTGGCACCAACGGGCAGGTGCGCTGCAGCCTGCGAGGCCACGACCACTTTGCCCTGCAGCGGGCC
TACGAGGACAGCTACATGATCGTCACCACGGCGGCGCTGGATCGCGAGCGCATCCCCGAGTACAATCTCACCGTGGTGG
CCGAGGACCTGGGCTCCCCGCCCTTCAAGACCGTCCGCCAGTACACGGTGCGGGTGAGCGACGAGAACGACAACGCGCC
GCTCTTTGCCAAGCCCCTCTATGAGGTGGCTGTGCCGGAGAACAACCCGCCAGGTGCCTACATCACCACTGTGGTGGCC
CGTGACCCTGATCTTGGCCACAATGGGAAGGTCACCTACCGGCTGCTGGAGACCCAAGTCATGGGGGCCCCAATCTCTA
CCTACGTCTCGGTTGACCCTGCCACTGGGGCCATCTATGCCCTCAGAACGTTCAACTATGAGATCCTCAAGCAGCTTGA
CCTGAGGATCCAGGCCACTGATGGAGGCTCCCCGCAGCTCTCCAGCAGCACGCTTGTCAAGGTGAGGATGGTGGACCAG
AATGACAACCCTCCAATCATCATCCACCCAGTGCTCACCAATGGGTCGGTGGAAATCAGTGTCTCCAGCAAGACCTCCC
GTGATGCCTTGGTGGCCCAGATCAAAGCCCGCGATGCAGATGATGGGGCCAACGCTGAGCTTACCTTTGCCTTCCTGGA
AGAACCCCAGCAGGACCTTTTTGCCATCAACCCAAGCACTGGAGACATCGTGCTGAGGGGTGACCTCTCTGAAGAGCTG
GGGCAGCTGTTCAAGGTCATCCTCACTGTGACAGATAATGGGAGGCCCCCTCTGGCCACAACTGCCACTGTTAACTTCC
TGGTGACCGCCACTGCTCCTTCCAGCATCCAGGAGGTAGCCAAGCCCAGCTCCTGGCAAGGAAAGGCCTTGCAGTGGGA
CATCCCTCTGATTGTGATCATCGTCCTGGCGGGCAGCTGCACCCTCCTCCTGGTGGCCATCATCACCATCGCCACCACC
TGCAACAGGCGCAAGAAAGGGAACGAGATCAAAAACAACAGTCCCCTGAAGGAGCAGATCGACATTTCCCACCTGGAGA
AGGGTCGGCAGGAGGACAGCAGCCAGAGGGGAAACGTGTTCGAGGTACGAACCTTCCCCAGCAAAACCCCTTTCAGCGG
CCCCGACCCCCCTTCAGCAGCTGAGGAGATCTCCACCGCGGAGAGCAGCAGCGACAGCGCCTGCCTCTACGACGGTCAG
AAGCGGCTCAGAGGAGCCGGCGGGGAGGGTTTCACCGCCGCTCCGAGCTTCGGCAAAGAGCCCGCTCCCCCCGTGGCCA
TTTGGAAGGGGCACTCCTTTAATACCATCTCGGGCCGGGAGGCAGAGAAGTTCAGCGGCAAGGACAGTGGCAAAGGCGA
CAGCGATTTCAACGACAGCGACTCGGACATCAGCGGGGATGCCCTGAAGAAGGACCTCATCACACACATGCAGAACGGT
CTGTGGGCTTGTACGGCCGAGTGCAAGATCCTGGGCCATTCGGACCGCTGCTGGAGCCCCTCCTGTGGCCGAGCCAACC
CGCATCCCTCTCCCCACCCTCCGGCGCCTCTCTCCACCTTCTGCAAAAGCACATCCTTGCCCCGGGACCCTCTCCGCAG
GGACAACTTTTACCAGGCCCAGCTGCCAAAGACAGTGGGGCTGCAGAGCGTCTATGAGAAGGTGTTGCACAGGGACTTT
GACCGGACGATCACGCTGCTGTCCCCTCCGCGTCCCGCTCGGCTCCCTGACCTCCAGGAGATTGGGGTGCCCCTCTACC
CGGCCCCCTCAACCAGATTCCTTGGCCCCCAGACTGATGCCACTGAGAAAGCATAACCTCCCCACCCCTGGCCCCATCC
GCACGACTCAGTTGCTCCTGGGAGCCTTTAAGTTATTGACCAGACCCGGTGTTGTACGTGTAAATATGCAAGATGTGCC
TTAAAACATGAAGGTGTTGGGAAAGATTTCCCGTCGGTACTGTTTGGTATTTGCAAACAACAGCAACAACAAAAATTGT
TTGTAGTTCATGTAATTTTTATGAAATGTGCAGTATTTAATTTTTTTTTTCCCCCTTTGTTTTCTACATGGTTTTCTTT
GCGTTTGGTTTGCCCATGGCCTGCCATTTTTGTAGTGTTTTTAACCTGTACAGTGTGTAATGTAATGTTTGTACATAAT
GAGAATTGGTTATATTTTTATATAATAAAAGCTTAAATAATGGGAATTCTTGCCAAAGGAACTGTCTGAGAGACACAAT
AATTATTATTAATATCCTGCATATGTAGAATCTTGTAAGGGAAATTCCTCTTCCGTAGTGTAATAGTAACCCAAGCAAC
ACAGTGTGCGGAGACGTTTGCCTTGCCAAATGTGATTTGTATCTCTTGAATCTGTAGTCGGTTTAAAGTTAAATGTTAT
TTAATTGCCTTTGGTTCCTGTAATCTGTGTCACTGATAAACACTAATAAAGGTTTTGTGATGTGTTGG
Commentsprobe not sequenced yet, this clone is supposed to be the NCBI long form: acc # XM_425623
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 5
Paraxial Mesoderm
Trunk Mesenchyme
Unlabeled
 
7-12
stage 7
stage 8
stage 9
stage 11
stage 11
Lateral Plate Mesoderm
Neural Crest
Paraxial Mesoderm
Somites
 
13-14
stage 13
stage 14
stage 14
Heart
Heart Tube
Hindbrain
Paraxial Mesoderm
Somites
Spinal Cord
 

Entry 2

GEISHA IdPCDH8.Watanabe.2009Data SourcePublication
Complete cDNA Template Probeshow
CAGCGGCAAGGACAGTGGCAAAGGCGACAGCGATTTCAACGACAGCGACTCGGACATCAGCGGGGATGCCCTGAAGAAG
GACCTCATCACACACATGCAGAACGGTCTGTGGGCTTGTACGGCCGAGTGCAAGATCCTGGGCCATTCGGACCGCTGCT
GGAGCCCCTCCTGTGGCCGAGCCAACCCGCATCCCTCTCCCCACCCTCCGGCGCCTCTCTCCACCTTCTGCAAAAGCAC
ATCCTTGCCCCGGGACCCTCTCCGCAGGGACAACTTTTACCAGGCCCAGCTGCCAAAGACAGTGGGGCTGCAGAGCGTC
TATGAGAAGGTGTTGCACAGGGACTTTGACCGGACGATCACGCTGCTGTCCCCTCCGCGTCCCGCTCGGCTCCCTGACC
TCCAGGAGATTGGGGTGCCCCTCTACCCGGCCCCCTCAACCAGATTCCTTGG
CitationWatanabe T, Sato Y, Saito D, Tadokoro R, Takahashi Y. EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation. Proc Natl Acad Sci U S A. 2009 May 5; 106(18): 7467–7472.
CopyrightCopyright 2009 national Academy of Sciences USA
CommentsThe probe was amplified by PCR using the following primers: 5′-GACAGCGGCAAGGAGACAGTGATTTCAATGACAGTGACTCGG-3′ and 5′-CCAAGGAATGTGGTTGAGGGGCCGGGTAGAGGGGCACCCC-3′ and was extracted from NCBI Acc# NM_001098609.1.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 12
stage 12
Somites
 

Entry 3

GEISHA IdPCDH8.Lin.2012Data SourcePublication
Complete cDNA Template Probeshow
TCGCGAGCGCCAGCCTTCCTACACCCTGGAGCTGGTGGCCAAGGACGGCGGCAGCCCTGCACGCTCAGGCACAGCCACG
GTGCACGTCCGCGTCCTCGATGCCAACGACAACAGCCCCACTTTTGCCCGGAGCTCTGTGACAGTGGAGCTGCCGGAAG
ACGCGCCGCCTGGCTCCCTGCTGCTTGACCTGGATGCCGAAGACCCCGACGAGGGCCCCAACGGAGAGGTCGTCTATGC
CTTTGGCAGTCAGGTGCCCCCTGAGGCACGGCGGCTCTTCCGCCTAGACCCACGCTCAGGCCGCCTGACGCTGGAGGCT
GCTGTGGACTACGAGCGTACCCGCACCTACGAGCTGGACGTGCGGGCCCAGGATCGCGGTGCCAGCCCCAGGACCGCGA
CCTGCACCGTCGTGGTGCGCCTTACCGACATCAACGACAACGCGCCACGCATCAGCATCAGCGCCCTGCGTGGTGCCGG
CAGCGCCGCCGGCGTGGCCTACGTCAGCGAGGCGGCTGCCAGTGAGAGCTTCGTGGCCCTCGTCAGCGCTTCCGACCGT
GACTCTGGCACCAACGGGCAGGTGCGCTGCAGCCTGCGAGGCCACGACCACTTTGCCCTGCAGCGGGCCTACGAGGACA
GCTACATGATCGTCACCACGGCGGCGCTGGATCGCGAGCGCATCCCCGAGTACAATCTCACCGTGGTGGCCGAGGACCT
GGGCTCCCCGCCCTTCAAGACCGTCCGCCAGTACACGGTGCGGGTGAGCGACGAGAACGACAACGCGCCGCTCTTTGCC
AAGCCCCTCTATGAGGTGGCTGTGCCGGAGAACAACCCGCCAGGTGCCTACATCACCACTGTGGTGGCCCGTGACCCTG
ATCTTGGCCACAATGGGAAGGTCACCTACCGGCTGCTGGAGACCCAAGTCATGGGGGCCCCAATCTCTACCTACGTCTC
GGTTGACCCTGCCACTGGGGCCATCTATGCCCTCAGAACGTTCAACTATGAGATCCTCAAGCAGCTTGACCTGAGGATC
CAGGCCACTGATGGGGGCTCCCCGCAGCTCTCCAGCAGCACGCTTGTCAAGGTGAGGATGGTGGACCAGAATGACAACC
CTCCAATCATCATCCACCCAGTGCTCACCAATGGGTCGGTGGAAATCAGTGTCTCCAGCAAGACCTCCCGTGATGCCTT
GGTGGCCCAGATCAAAGCCCGCGATGCAGATGATGGGGCCAACGCTGAGCTTACCTTTGCCTTCCTGGAAGAACCCCAG
CAGGACCTTTTTGCCATCAACCCAAGCACTGGAGACATCGTGCTGAGGGGTGACCTCTCTGAAGAGCTGGGGCAGCTGT
TCAAGGTCATCCTCACTGTGACAGATAATGGGAGGCCCCCTCTGGCCACAACTGCCACTGTTAACTTCCTGGTGACCGC
CACTGCTCCTTCCAGCATCCAGGAGGTAGCCAAGCCCAGCTCCTGGCAAGGAAAGGCCTTGCAGTGGGACATCCCTCTG
ATTGTGATCATTGTCCTGGCGGGCAGCTGCACCCTCCTCCTGGTGGCCATCATCACCATCGCCACCACCTGCAACAGGC
GCAAGAAAGGGAACGAGATCAAAAACAACAGTCCCCTGAAGGAGCAGATCGACATTTCCCACCTGGAGAAGGGTCGGCA
GGAGGACAGCAGCCAGAGGGGAAACGTGTTCGAGGTACGAACCTTCCCCAGCAAAACCCCTTTCAGCGGCCCCGACCCC
CCTTCAGCAGCTGAGGAGATCTCCACCGCGGAGAGCAGCAGCGACAGCGCCTGCCTCTACGACGGTCAGAAGCGGCTCA
GAGGAGCCAGCGGGGAGCAGG
CitationLin J, Wang C, Redies C Expression of delta-protocadherins in the spinal cord of the chicken embryo. J Comp Neurol. 2012 May 1;520(7):1509-31.
CopyrightCopyright © 2011 Wiley Periodicals, Inc.
CommentsThe cDNA template used to generate the probe was obtained by PCR as described in the paper.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 18
stage 18
Spinal Cord
 
19-24
stage 20
stage 24
stage 24
stage 24
stage 24
stage 24
stage 24
stage 24
stage 24
stage 24
Notochord
Spinal Cord
Spinal Ganglia and Nerves
Cdh7: green
Higher magnification of boxed area in C.
Pax3: red
Pcdh10: green
Pcdh18: red
Pcdh7: red
Pcdh8: green
Pcdh8: red
ncc, neural crest cells
25-30
stage 29
stage 29
stage 30
stage 30
stage 30
stage 30
stage 30
stage 30
stage 30
stage 30
stage 30
stage 30
Spinal Cord
Spinal Ganglia and Nerves
Cervical section of the spine.
Higher magnification of boxed are in E.
Higher magnification of boxed area in G.
Immunostaining: Islet1 in red
In situ hybridization: PC8 in green
Lumbar section of the spine.
PC8: green fluorescence
Sacral section of the spine.
Thoracic section of the spine.
dh, dorsal horn
31-36
stage 34
stage 34
stage 36
stage 36
Spinal Cord
Spinal Ganglia and Nerves
Higher magnification of boxed area in I.
Higher magnification of the boxed area in K.
lm, lateral motor column
me, meninges
rp, roof plate

Entry 4

GEISHA IdPCDH8.Lin.2013Data SourcePublication
Complete cDNA Template Probeshow
TCGCGAGCGCCAGCCTTCCTACACCCTGGAGCTGGTGGCCAAGGACGGCGGCAGCCCTGCACGCTCAGGCACAGCCACG
GTGCACGTCCGCGTCCTCGATGCCAACGACAACAGCCCCACTTTTGCCCGGAGCTCTGTGACAGTGGAGCTGCCGGAAG
ACGCGCCGCCTGGCTCCCTGCTGCTTGACCTGGATGCCGAAGACCCCGACGAGGGCCCCAACGGAGAGGTCGTCTATGC
CTTTGGCAGTCAGGTGCCCCCTGAGGCACGGCGGCTCTTCCGCCTAGACCCACGCTCAGGCCGCCTGACGCTGGAGGCT
GCTGTGGACTACGAGCGTACCCGCACCTACGAGCTGGACGTGCGGGCCCAGGATCGCGGTGCCAGCCCCAGGACCGCGA
CCTGCACCGTCGTGGTGCGCCTTACCGACATCAACGACAACGCGCCACGCATCAGCATCAGCGCCCTGCGTGGTGCCGG
CAGCGCCGCCGGCGTGGCCTACGTCAGCGAGGCGGCTGCCAGTGAGAGCTTCGTGGCCCTCGTCAGCGCTTCCGACCGT
GACTCTGGCACCAACGGGCAGGTGCGCTGCAGCCTGCGAGGCCACGACCACTTTGCCCTGCAGCGGGCCTACGAGGACA
GCTACATGATCGTCACCACGGCGGCGCTGGATCGCGAGCGCATCCCCGAGTACAATCTCACCGTGGTGGCCGAGGACCT
GGGCTCCCCGCCCTTCAAGACCGTCCGCCAGTACACGGTGCGGGTGAGCGACGAGAACGACAACGCGCCGCTCTTTGCC
AAGCCCCTCTATGAGGTGGCTGTGCCGGAGAACAACCCGCCAGGTGCCTACATCACCACTGTGGTGGCCCGTGACCCTG
ATCTTGGCCACAATGGGAAGGTCACCTACCGGCTGCTGGAGACCCAAGTCATGGGGGCCCCAATCTCTACCTACGTCTC
GGTTGACCCTGCCACTGGGGCCATCTATGCCCTCAGAACGTTCAACTATGAGATCCTCAAGCAGCTTGACCTGAGGATC
CAGGCCACTGATGGGGGCTCCCCGCAGCTCTCCAGCAGCACGCTTGTCAAGGTGAGGATGGTGGACCAGAATGACAACC
CTCCAATCATCATCCACCCAGTGCTCACCAATGGGTCGGTGGAAATCAGTGTCTCCAGCAAGACCTCCCGTGATGCCTT
GGTGGCCCAGATCAAAGCCCGCGATGCAGATGATGGGGCCAACGCTGAGCTTACCTTTGCCTTCCTGGAAGAACCCCAG
CAGGACCTTTTTGCCATCAACCCAAGCACTGGAGACATCGTGCTGAGGGGTGACCTCTCTGAAGAGCTGGGGCAGCTGT
TCAAGGTCATCCTCACTGTGACAGATAATGGGAGGCCCCCTCTGGCCACAACTGCCACTGTTAACTTCCTGGTGACCGC
CACTGCTCCTTCCAGCATCCAGGAGGTAGCCAAGCCCAGCTCCTGGCAAGGAAAGGCCTTGCAGTGGGACATCCCTCTG
ATTGTGATCATTGTCCTGGCGGGCAGCTGCACCCTCCTCCTGGTGGCCATCATCACCATCGCCACCACCTGCAACAGGC
GCAAGAAAGGGAACGAGATCAAAAACAACAGTCCCCTGAAGGAGCAGATCGACATTTCCCACCTGGAGAAGGGTCGGCA
GGAGGACAGCAGCCAGAGGGGAAACGTGTTCGAGGTACGAACCTTCCCCAGCAAAACCCCTTTCAGCGGCCCCGACCCC
CCTTCAGCAGCTGAGGAGATCTCCACCGCGGAGAGCAGCAGCGACAGCGCCTGCCTCTACGACGGTCAGAAGCGGCTCA
GAGGAGCCAGCGGGGAGCAGG
CitationLin J, Wang C, Redies C. Expression of multiple delta-protocadherins during feather bud formation. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):57-65. Epub 2013 Jan 11.. DIO: 10.1016/j.gep.2013.01.001.
CopyrightCopyright © 2013 Elsevier B.V. All rights reserved.
CommentsThe complete cDNA template sequence was obtained from the information from the publication as described in Lin et al. 2013.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-36
stage 34
stage 35
stage 35
stage 35
stage 36
Surface Ectoderm
ib, interbud region
in situ (red): PCDH8
all
 
 
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.30329

Mouse

EmageMGI:1306800
EurexpressMGI:1306800
MGI GXDMGI:1306800

Frog

Xenbase5887885

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-980526-242
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