GEISHA - A Chicken Embryo Gene Expression Database
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PITX1
paired like homeodomain 1

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolPITX1
Official Full Namepaired like homeodomain 1
CGNC ID4791
also known asPTX1, pituitary homeobox 1|cPTX1|homeobox protein PITX1|paired-like homeodomain transcription factor 1, Pituitary homeobox 1
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001167684
PolypeptideNP_001161156
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.962
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human5307ENSG00000069011MIM:119800MIM:602149
Mouse18740ENSMUSG00000021506All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2) MGI:107374
Xenopus493226, 394310485440
Zebrafish678598ZDB-GENE-060421-3623ZFIN:ZDB-GENE-060421-3623
Gene Ontology
Molecular Functionsequence-specific DNA binding, sequence-specific DNA binding transcription factor activity
Biological Processmulticellular organismal development, transcription, DNA-templated
Cellular Componentnucleus
Links to other databases
Entrez Gene374201
Ensembl Gene
KEGGgga:374201

Entry 1

GEISHA IdChEST656i21Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
CACTTTCCTGCCTATGCGGCCGGACTGCCGTGCCTCTCCCCGCGCAGAGCCCGGCGGCTTCCAGGCGCTGCCCAGATCT
CTTCCTCCGACACCCTTAAAATAATACTGTTAGTAATAAGTGGATTTGCTTTTGTTTTTTGTTGTGTTTTGTTGTGTTT
TTTTTTTTCCCTTAAAGAACAAAAAGGAAAAAAAAAGAGAGAAAAATATATATATATTAAAAAAAAGCTCCTTGTTCCT
TTCTGTGTGGAATAAACACCTGCAAACTCCCCCAGGCAGCCCGGCGCCCCCGCCATGGATTCCTTTAAAGGTGGAATGA
ATTTGGAGAGACTGCCCGAGAGCTTGAGACCCCAACCCTCCCATGACATGGCTTCCAGCTTCCATTTGCAAAGATCCTC
GGAGCCCAGAGACCCGATCGAGAACTCGGCCAGTGAATCCTCCGACACGGAGGTGCCAGAAAAAGAGAGAAGCGGAGAG
CAGAAAAACGAGGACGGGGCCGCCGACGACCCGGCGAAGAAGAAGAAGCAACGGAGGCAGCGGACCCACTTCACCAGCC
AGCAGCTGCAGGAGCTGGAGGCCACCTTCCAGCGGAACCGCTACCCCGATATGAGCATGCGGGAGGAGATCGCCGTGTG
GACGAACCTCACCGAGCCCCGCGTCCGGGTGTGGTTCAAGAACCGCCGAGCCAAGTGGAGAAAGCGGGAGCGGAACCAG
CAGATGGACCTGTGCAAGAACCGCTACTTGCCGCAGTTCACCGGGCTGAATGCACCCTACAACGACATGTACGCCGGGT
ACCCCTAAAAAAACTGGGCCACCAAGAACCTAAACCCGGGGCCGCTTTCCACAAAAAGCTTAACTTTCTTCAATTCCGT
AACCCCCCTTCCCTCGAATTCCATGTTTTCGGCCCCCAAAAGAATCTCCTCAAAAAAAAGCCCTCCGGGAAGGGCCATT
TAGCCTTGTGGGGATGGACAAATTCGGGCTCAAAAAATAAAAAAAATAAGAGCTCCTCGTAAACTT
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 5
stage 6
stage 6
Area Opaca
Lateral Plate Mesoderm
 
7-12
stage 7
stage 7
stage 9
stage 9
stage 9
stage 10
stage 10
stage 12
stage 12
stage 12
stage 12
stage 12
Area Opaca
Endoderm
Extraembryonic
Extraembryonic Blood Vessels
Forebrain
Foregut
Head Process
Headfold
Lateral Plate Mesoderm
Oral Pharynx
Pharynx
Pituitary (Rudiment)
extraembryonic ectoderm
extraembryonic endoderm
Dorsal
NOTE: real stain at base of AIP
Ventral
13-18
stage 14
stage 14
stage 14
stage 14
stage 15
stage 15
stage 16
stage 18
stage 18
Allantois
Amnion
Endoderm
Extraembryonic
Eye
Foregut
Lateral Plate Mesoderm
Leg Mesenchyme
Midgut
Oral Pharynx
Pharyngeal Arches and Clefts
Pharynx
extraembryonic ectoderm
extraembryonic endoderm
optic cup
25
stage 25
stage 25
stage 25
stage 25
stage 25
Allantois
Dermomyotome
Eye
Face Mesenchyme
Gut
Hindgut
Leg
Leg Mesenchyme
Midgut
Oral Pharynx
Pharyngeal Arches and Clefts
Spinal Cord
Spinal Ganglia and Nerves
Wing Mesenchyme
 

Entry 2

GEISHA IdPitx1.Holleville.2007Data SourcePublication
Complete cDNA Template Probeshow
CACTTTCCTGCCTATGCGGCCGGACTGCCGTGCCTCTCCCCGCGCAGAGCCCGGCGGCTTCCAGGCGCTGCCCAGATCT
CTTCCTCCGACACCCTTAAAATAATACTGTTAGTAATAAGTGGATTTGCTTTTGTTTTTTGTTGTGTTTTGTTGTGTTT
TTTTTTTTTCCCTTAAAGAACAAAAAGGAAAAAAAAAGAGAGAAAAATATATATATATTAAAAAAAAGCTCCTTGTTCC
TTTCTGTGTGGAATAAACACCTGCAAACTCCCCCAGGCAGCCCGGCGCCCCCGCCATGGATTCCTTTAAAGGTGGAATG
AATTTGGAGAGACTGCCCGAGAGCTTGAGACCCCAACCCTCCCATGACATGGCTTCCAGCTTCCATTTGCAAAGATCCT
CGGAGCCCAGAGACCCGATCGAGAACTCGGCCAGTGAATCCTCCGACACGGAGGTGCCAGAAAAAGAGAGAAGCGGAGA
GCAGAAAAACGAGGACGGGGCCGCCGACGACCCGGCGAAGAAGAAGAAGCAACGGAGGCAGCGGACCCACTTCACCAGC
CAGCAGCTGCAGGAGCTGGAAGCCACTTTCCAGCGGAACCGCTACCCCGATATGAGCATGCGGGAGGAGATCGCCGTGT
GGACGAACCTCACCGAGCCCCGCGTCCGGGTGTGGTTCAAGAACCGCCGAGCCAAGTGGAGAAAGCGGGAGCGGAACCA
GCAGATGGACCTGTGCAAGAACGGCTACGTGCCGCAGTTCAGCGGGCTGATGCAGCCCTACGACGACATGTACGCCGGG
TACCCCTACAACAAATGGGCCACCAAAAGCCTCACCCCGGCGCCGCTCTCCACCAAGAGCTTCACCTTCTTCAACTCCA
TGAGCCCCCTCTCCTCGCAGTCCATGTTCTCGGCTCCCAGCAGCATCTCCTCCATGAACATGCCCTCCGGGATGGGCCA
CTCGGCCGTGCCGGGCATGGCCAACTCCGGCCTCAACAACATCAACAACATCAGCGGCTCCTCGCTCAACTCGGCCATG
TCCTCGCCCGCTTGTCCCTATGGGCCGCCGGGCTCTCCCTACAGCGTGTACCGGGACACTTGTAACTCCAGCCTGGCCA
GCCTCAGACTGAAATCAAAGCAGCACTCCAGTTTCGGCTACAGCAGTTTGCAGAGCCCCGGCTCCAGCCTAAACGCCTG
TCAGTACAACAGTTGACGGACTTGACACGAACCACCTCCGACGAACACCGCCGACAAAGCAAAAAATACTAAGAAAAAA
TAAAAAACAAAGCAGAAACAAAGCGACGTTTAACGGAAATGAATATTTATATATATATGTATGTATGTAGAAACCCGAT
GATGTGTAAAAGCAAAACCCGAGCAAGTGAGAGAGGGAAAGAAACAGCACAAAAAGAAAGCAAAAAGGCAAAACAATGA
TGATGATAATGATAATAAAACAAAACCCGAAAGCTCTGCGGACTTCGATTGTCTAAAAGATAATAATAATAAACAAAAA
CAAATGAATAGAAAAAGAGATCCGACGACACAACCAACAAAGCAGCGCTTTAAAAACAAACCATTTGTAACCATTAAAA
AGCAAACCACCAAAAAAAATTAAAAAAAATAAATAAAAATAAAAAACCAAAAAAACGGAAAAGGACCAGAAAACTTTTG
CAAGAGACACCGAAATCTGGTACATGGATGAGTTGCAATTTTTCTCTGGATGATGCGGGTTGTATGTGTTTACTTGAAC
TTGCACAGGAGGTGGTAAGGCGGCCGCTCCCCGCGGCAGCGCGGCCATTGGGGACGGCCCGGGGGGAGCGCTGGGGGCG
GCGGCGGCCGCGGGCGCACGGGGGTGGGGGGTAGGGAGGGGAGGGGGGAAGTTCGGGTGATGTTTACCACTGAGAAACG
GAATCACGCTCCAAAAAGGAAAAAAAAAAAAAAAGAAAAAAAGAAGG
CitationHolleville N, Matéos S, Bontoux M, Bollerot K, Monsoro-Burq AH. Dlx5 drives Runx2 expression and osteogenic differentiation in developing cranial suture mesenchyme. Dev Biol. 2007 Apr 15;304(2):860-74.
CopyrightReprinted with permission from Elsevier. Copyright © 2007 Elsevier B.V. All rights reserved.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # XM_414626.2).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-38
stage 38
Face Mesenchyme
 

Entry 3

GEISHA IdPITX1.Parkinson.2010Data SourcePublication
Complete cDNA Template Probeshow
CACTTTCCTGCCTATGCGGCCGGACTGCCGTGCCTCTCCCCGCGCAGAGCCCGGCGGCTTCCAGGCGCTGCCCAGATCT
CTTCCTCCGACACCCTTAAAATAATACTGTTAGTAATAAGTGGATTTGCTTTTGTTTTTTGTTGTGTTTTGTTGTGTTT
TTTTTTTTTCCCTTAAAGAACAAAAAGGAAAAAAAAAGAGAGAAAAATATATATATATTAAAAAAAAGCTCCTTGTTCC
TTTCTGTGTGGAATAAACACCTGCAAACTCCCCCAGGCAGCCCGGCGCCCCCGCCATGGATTCCTTTAAAGGTGGAATG
AATTTGGAGAGACTGCCCGAGAGCTTGAGACCCCAACCCTCCCATGACATGGCTTCCAGCTTCCATTTGCAAAGATCCT
CGGAGCCCAGAGACCCGATCGAGAACTCGGCCAGTGAATCCTCCGACACGGAGGTGCCAGAAAAAGAGAGAAGCGGAGA
GCAGAAAAACGAGGACGGGGCCGCCGACGACCCGGCGAAGAAGAAGAAGCAACGGAGGCAGCGGACCCACTTCACCAGC
CAGCAGCTGCAGGAGCTGGAAGCCACTTTCCAGCGGAACCGCTACCCCGATATGAGCATGCGGGAGGAGATCGCCGTGT
GGACGAACCTCACCGAGCCCCGCGTCCGGGTGTGGTTCAAGAACCGCCGAGCCAAGTGGAGAAAGCGGGAGCGGAACCA
GCAGATGGACCTGTGCAAGAACGGCTACGTGCCGCAGTTCAGCGGGCTGATGCAGCCCTACGACGACATGTACGCCGGG
TACCCCTACAACAAATGGGCCACCAAAAGCCTCACCCCGGCGCCGCTCTCCACCAAGAGCTTCACCTTCTTCAACTCCA
TGAGCCCCCTCTCCTCGCAGTCCATGTTCTCGGCTCCCAGCAGCATCTCCTCCATGAACATGCCCTCCGGGATGGGCCA
CTCGGCCGTGCCGGGCATGGCCAACTCCGGCCTCAACAACATCAACAACATCAGCGGCTCCTCGCTCAACTCGGCCATG
TCCTCGCCCGCTTGTCCCTATGGGCCGCCGGGCTCTCCCTACAGCGTGTACCGGGACACTTGTAACTCCAGCCTGGCCA
GCCTCAGACTGAAATCAAAGCAGCACTCCAGTTTCGGCTACAGCAGTTTGCAGAGCCCCGGCTCCAGCCTAAACGCCTG
TCAGTACAACAGTTGACGGACTTGACACGAACCACCTCCGACGAACACCGCCGACAAAGC
CitationParkinson N, Collins MM, Dufresne L, Ryan AK. Expression patterns of hormones, signaling molecules, and transcription factors during adenohypophysis development in the chick embryo. Dev Dyn. 2010 Apr;239(4):1197-210.
CopyrightCopyright © 2010 Wiley-Liss, Inc.
CommentsAs insufficient information is provided in publication to verify the exact sequence used to synthesize the probes, the sequence below was obtained from NCBI (acc# NM_001167684.1)
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 21
Pituitary (Rudiment)
 
25-30
stage 27
Pituitary (Rudiment)
 
31-36
stage 32
stage 36
stage 36
Pituitary (Rudiment)
 

Entry 4

GEISHA IdPITX1.Brito.2006Data SourcePublication
Complete cDNA Template Probeshow
CACTTTCCTGCCTATGCGGCCGGACTGCCGTGCCTCTCCCCGCGCAGAGCCCGGCGGCTTCCAGGCGCTGCCCAGATCT
CTTCCTCCGACACCCTTAAAATAATACTGTTAGTAATAAGTGGATTTGCTTTTGTTTTTTGTTGTGTTTTGTTGTGTTT
TTTTTTTTTCCCTTAAAGAACAAAAAGGAAAAAAAAAGAGAGAAAAATATATATATATTAAAAAAAAGCTCCTTGTTCC
TTTCTGTGTGGAATAAACACCTGCAAACTCCCCCAGGCAGCCCGGCGCCCCCGCCATGGATTCCTTTAAAGGTGGAATG
AATTTGGAGAGACTGCCCGAGAGCTTGAGACCCCAACCCTCCCATGACATGGCTTCCAGCTTCCATTTGCAAAGATCCT
CGGAGCCCAGAGACCCGATCGAGAACTCGGCCAGTGAATCCTCCGACACGGAGGTGCCAGAAAAAGAGAGAAGCGGAGA
GCAGAAAAACGAGGACGGGGCCGCCGACGACCCGGCGAAGAAGAAGAAGCAACGGAGGCAGCGGACCCACTTCACCAGC
CAGCAGCTGCAGGAGCTGGAAGCCACTTTCCAGCGGAACCGCTACCCCGATATGAGCATGCGGGAGGAGATCGCCGTGT
GGACGAACCTCACCGAGCCCCGCGTCCGGGTGTGGTTCAAGAACCGCCGAGCCAAGTGGAGAAAGCGGGAGCGGAACCA
GCAGATGGACCTGTGCAAGAACGGCTACGTGCCGCAGTTCAGCGGGCTGATGCAGCCCTACGACGACATGTACGCCGGG
TACCCCTACAACAAATGGGCCACCAAAAGCCTCACCCCGGCGCCGCTCTCCACCAAGAGCTTCACCTTCTTCAACTCCA
TGAGCCCCCTCTCCTCGCAGTCCATGTTCTCGGCTCCCAGCAGCATCTCCTCCATGAACATGCCCTCCGGGATGGGCCA
CTCGGCCGTGCCGGGCATGGCCAACTCCGGCCTCAACAACATCAACAACATCAGCGGCTCCTCGCTCAACTCGGCCATG
TCCTCGCCCGCTTGTCCCTATGGGCCGCCGGGCTCTCCCTACAGCGTGTACCGGGACACTTGTAACTCCAGCCTGGCCA
GCCTCAGACTGAAATCAAAGCAGCACTCCAGTTTCGGCTACAGCAGTTTGCAGAGCCCCGGCTCCAGCCTAAACGCCTG
TCAGTACAACAGTTGACGGACTTGACACGAACCACCTCCGACGAACACCGCCGACAAAGC
CitationJosé M. Brito, Marie-Aimée Teillet, Nicole M. Le Douarin. An early role for Sonic hedgehog from foregut endoderm in jaw development: Ensuring neural crest cell survival. Proc Natl Acad Sci U S A. 2006 August 1; 103(31): 11607–11612.
CopyrightCopyright © 2006 by The National Academy of Sciences of the USA
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-21
stage 21
stage 21
Pharyngeal Arches and Clefts
 

Entry 5

GEISHA IdPITX1.Szeto.1999Data SourcePublication
Complete cDNA Template Probeshow
CACTTTCCTGCCTATGCGGCCGGACTGCCGTGCCTCTCCCCGCGCAGAGCCCGGCGGCTTCCAGGCGCTGCCCAGATCT
CTTCCTCCGACACCCTTAAAATAATACTGTTAGTAATAAGTGGATTTGCTTTTGTTTTTTGTTGTGTTTTGTTGTGTTT
TTTTTTTTTCCCTTAAAGAACAAAAAGGAAAAAAAAAGAGAGAAAAATATATATATATTAAAAAAAAGCTCCTTGTTCC
TTTCTGTGTGGAATAAACACCTGCAAACTCCCCCAGGCAGCCCGGCGCCCCCGCCATGGATTCCTTTAAAGGTGGAATG
AATTTGGAGAGACTGCCCGAGAGCTTGAGACCCCAACCCTCCCATGACATGGCTTCCAGCTTCCATTTGCAAAGATCCT
CGGAGCCCAGAGACCCGATCGAGAACTCGGCCAGTGAATCCTCCGACACGGAGGTGCCAGAAAAAGAGAGAAGCGGAGA
GCAGAAAAACGAGGACGGGGCCGCCGACGACCCGGCGAAGAAGAAGAAGCAACGGAGGCAGCGGACCCACTTCACCAGC
CAGCAGCTGCAGGAGCTGGAAGCCACTTTCCAGCGGAACCGCTACCCCGATATGAGCATGCGGGAGGAGATCGCCGTGT
GGACGAACCTCACCGAGCCCCGCGTCCGGGTGTGGTTCAAGAACCGCCGAGCCAAGTGGAGAAAGCGGGAGCGGAACCA
GCAGATGGACCTGTGCAAGAACGGCTACGTGCCGCAGTTCAGCGGGCTGATGCAGCCCTACGACGACATGTACGCCGGG
TACCCCTACAACAAATGGGCCACCAAAAGCCTCACCCCGGCGCCGCTCTCCACCAAGAGCTTCACCTTCTTCAACTCCA
TGAGCCCCCTCTCCTCGCAGTCCATGTTCTCGGCTCCCAGCAGCATCTCCTCCATGAACATGCCCTCCGGGATGGGCCA
CTCGGCCGTGCCGGGCATGGCCAACTCCGGCCTCAACAACATCAACAACATCAGCGGCTCCTCGCTCAACTCGGCCATG
TCCTCGCCCGCTTGTCCCTATGGGCCGCCGGGCTCTCCCTACAGCGTGTACCGGGACACTTGTAACTCCAGCCTGGCCA
GCCTCAGACTGAAATCAAAGCAGCACTCCAGTTTCGGCTACAGCAGTTTGCAGAGCCCCGGCTCCAGCCTAAACGCCTG
TCAGTACAACAGTTGACGGACTTGACACGAACCACCTCCGACGAACACCGCCGACAAAGC
CitationSzeto DP, Rodriguez-Esteban C, Ryan AK, O'Connell SM, Liu F, Kioussi C, Gleiberman AS, Izpisúa-Belmonte JC, Rosenfeld. Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev. 1999 February 15; 13(4): 484–494.
CopyrightCopyright © 1999, Cold Spring Harbor Laboratory Press
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_001167684.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 16
stage 17
Leg
 
19-24
stage 20
stage 22
stage 24
Leg
 
25-29
stage 25
stage 29
stage 29
Leg
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.962

Mouse

EmageMGI:107374
EurexpressMGI:107374
MGI GXDMGI:107374

Frog

Xenbase485440

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-060421-3623
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